483 A Novel Metabolic Anti-cancer Therapy – Targeting Liver Tumors Through Mitochondrial Damage von Tesori, V, Piscaglia, A.C, Barba, M, Puglisi, M.A, Pani, G, Gasbarrini, G, Gasbarrini, A

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P.01.7 AMPK ACTIVATION IN COLON CANCER CELLS INHIBITS THE MALIGNANT PHENOTYPE INDUCING DIFFERENTIATION: POTENTIAL USE OF METFORMIN IN THE TREATMENT OF COLORECTAL CANCER von Tesori, V, Puglisi, M.A, Chiatamone Ranieri, S, Gasbarrini, G, Gasbarrini, A

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OC.10.6 NUTRIENTS AVAILABILITY AND DIFFERENTIATION REGULATE LGR5 RECEPTORS IN COLON CANCER: IMPLICATIONS FOR METABOLIC THERAPIES von Tesori, V, Puglisi, M.A, Lattanzi, W, Gasbarrini, G, Gasbarrini, A

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490 Role of Nitrogen Species in Gastrointestinal Cancer Stem Cells von Puglisi, M.A, Tesori, V, Lattanzi, W, Giorda, E, Carsetti, R, Cittadini, A, Gasbarrini, G.B, Michetti, F, Pani, G, Gasbarrini, A

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OC.08.5 NITRIC OXIDE IS ESSENTIAL IN REGULATING TUMOUR INITIATING PROPERTIES OF COLON CANCER STEM CELLS von Puglisi, M.A, Tesori, V, Ricci-Vitiani, L, Martini, M, Carsetti, R, Gasbarrini, G.B, Pani, G, Gasbarrini, A

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P.11.23 LOW CONTENT OF REACTIVE OXYGEN SPECIES (ROS) AS A MARKER OF HEPATIC CSC; IMPLICATIONS FOR NEW TARGETED THERAPIES von Tesori, V, Puglisi, M.A, Pani, G, Gasbarrini, G, Gasbarrini, A, Piscaglia, A.C

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OC.12.5 ROLE OF NITROGEN SPECIES IN COLON CANCER STEM CELLS von Puglisi, M.A, Tesori, V, Lattanzi, W, Giorda, E, Carsetti, R, Cittadini, A, Gasbarrini, G, Michetti, F, Pani, G, Gasbarrini, A

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F-40 A novel metabolic action for the multikinase inhibitor sorafenib: targeting tumor cells through mitochondrial damage von Tesori, V, Piscaglia, A.C, Barba, M, Puglisi, M.A, Gasbarrini, G, Pani, G, Gasbarrini, A

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OC.08.1 CD133 ANTIGEN IS ASSOCIATED WITH COLONY FORMATION AND INVASIVENESS ABILTY IN COLORECTAL CANCER CELLS BY MODULATION OF SPECIFIC GENE PROFILES von Puglisi, M.A, Corbi, M, Tesori, V, Lattanzi, W, Barba, M, Boninsegna, A, Michetti, F, Cittadini, A, Gasbarrini, G.B, Sgambato, A, Gasbarrini, A

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OC.08.3: IDENTIFICATION OF ENDOTHELIN-1 AND NR4A2 AS CD133-REGULATED GENES IN COLON CANCER CELLS von Puglisi, M.A, Sgambato, A, Barba, M, Errico, M.F, Giorda, E, Saulnier, N, Boninsegna, A, Piscaglia, A.C, Carsetti, R, Cittadini, A, Gasbarrini, G.B, Gasbarrini, A

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528 IN VITRO EVALUATION OF HEPATIC TRANSDIFFERENTIATION OF ADIPOSE- AND BONE MARROW-DERIVED STROMAL CELLS von Saulnier, N, Puglisi, M.A, Barba, M, Piscaglia, A.C, Novi, M, Lauritano, E.C, Alfieri, S, Leone, G, Gasbarrini, G, Gasbarrini, A

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399 BONE MARROW STEM CELLS EXPRESSING CD34 ARE MOBILIZED IN DIFFERENT HISTOTYPES OF LIVER CANCER von Novi, M, Rinninella, E, Piscaglia, A.C, Lauritano, E.C, Zocco, M.A, Saulnier, N, Puglisi, M.A, Giuliante, F, Barbaro, F, Serricchio, M.L, Rumi, C, Leone, G, Nuzzo, G, Ghirlanda, G, Gasbarrini, A

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ADIPOSE TISSUE DERIVED-MESENCHYMAL STEM CELLS INJECTION AMELIORATES DSS INDUCED COLITIS IN MICE von Scaldaferri, F, Puglisi, M.A, Saulnier, N, Papa, A, Fiore, F, Arena, V, Stigliano, E, Caristo, M.E, Gasbarrini, A

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508 HUMAN LIVER AS A SOURCE OF MESENCHYMAL-LIKE STEM CELLS von Colombo, F, Ratti, R, Saulnier, N, Porretti, L, Cattaneo, A, Puglisi, M.A, Rossi, G, Piccolo, G, Foglieni, B, Gasbarrini, A, Prati, D

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Characterization of mesenchymal stem cells-like in human liver von Ratti, R, Saulnier, N, Colombo, F, Porretti, L, Cattaneo, A, Puglisi, M.A, Rossi, G, Piccolo, G, Foglieni, B, Prati, D

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TUMOR-INITIATING CELLS IN COLON CANCER AND LIVER METASTASES: BIOLOGICAL AND MOLECULAR CHARACTERIZATION von Puglisi, M.A, Saulnier, N, Sgambato, A, Rafanelli, F, Barba, M, Piscaglia, A.C, Boninsegna, A, Giorda, E, Carsetti, R, Giuliante, F, Alfieri, S, Persiani, R, Cittadini, A, Gasbarrini, A

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In vitro evaluation of hepatic transdifferentiation of adipose- and bone marrow-derived stromal cells von Saulnier, N, Puglisi, M.A, Barba, M, Novi, M.L, Piscaglia, A.C, Zocco, M.A, Fiore, F, Alfieri, S, Leone, G, Doglietto, G.B, Gasbarrini, G, Gasbarrini, A

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Biological and molecular characterization of tumor-initiating cells in colon cancer and liver metastasis von Puglisi, M.A, Saulnier, N, Barba, M, Sgambato, A, Rafanelli, F, Boninsegna, A, Barbaro, F, Campanale, M.C, Rinninella, E, Giorda, E, Carsetti, R, Giuliante, F, Nuzzo, G, Persiani, R, Alfieri, S, Cittadini, A, Piscaglia, A.C, Gasbarrini, A

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OC3.06.4 HUMAN COLON CANCER OVEREXPRESSES A CD133+ SUBPOPULATION ENDOWING CHARACTERISTICS OF “TUMOR-INITIATING CELLS” von Puglisi, M.A, Saulnier, N, Sgambato, A, Barba, M, Rafanelli, F, Lauritano, E.C, Boninsegna, A, Piscaglia, A.C, Novi, M.L, Zocco, M.A, Barbaro, F, Fiore, F, Alfieri, S, Doglietto, G.B, Cittadini, A, Michetti, F, Gasbarrini, A

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OC3.01.4 CD133+: A NEW MARKER OF CANCER INITIATING CELLS IN HUMAN CHOLANGIOCARCINOMA? von Puglisi, M.A, Saulnier, N, Sgambato, A, Barba, M, Rafanelli, F, Novi, M.L, Boninsegna, A, Piscaglia, A.C, Lauritano, E.C, Zocco, M.A, Rinninella, E, Campanale, C, Fiore, F, Giuliante, F, Nuzzo, G, Cittadini, A, Michetti, F, Gasbarrini, A

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