Site-selective Suzuki-Miyaura coupling of heteroaryl halides - understanding the trends for pharmaceutically important classes von Almond-Thynne, Joshua, Blakemore, David C, Pryde, David C, Spivey, Alan C

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Structural basis for inhibition of a voltage-gated Ca2+ channel by Ca2+ antagonist drugs von Tang, Lin, Gamal El-Din, Tamer M., Swanson, Teresa M., Pryde, David C., Scheuer, Todd, Zheng, Ning, Catterall, William A.

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Prokaryotic NavMs channel as a structural and functional model for eukaryotic sodium channel antagonism von Bagnéris, Claire, DeCaen, Paul G., Naylor, Claire E., Pryde, David C., Nobeli, Irene, Clapham, David E., Wallace, B. A.

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G10 is a direct activator of human STING von Banerjee, Monali, Middya, Sandip, Shrivastava, Ritesh, Basu, Sourav, Ghosh, Rajib, Pryde, David C, Yadav, Dharmendra B, Surya, Arjun

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The discovery of potent small molecule activators of human STING von Pryde, David C., Middya, Sandip, Banerjee, Monali, Shrivastava, Ritesh, Basu, Sourav, Ghosh, Rajib, Yadav, Dharmendra B., Surya, Arjun

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The discovery of potent small molecule cyclic urea activators of STING von Basu, Sourav, Middya, Sandip, Banerjee, Monali, Ghosh, Rajib, Pryde, David C., Yadav, Dharmendra B., Shrivastava, Ritesh, Surya, Arjun

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Selection of a novel anti-nicotine vaccine: influence of antigen design on antibody function in mice von Pryde, David C, Jones, Lyn H, Gervais, David P, Stead, David R, Blakemore, David C, Selby, Matthew D, Brown, Alan D, Coe, Jotham W, Badland, Matthew, Beal, David M, Glen, Rebecca, Wharton, Yvonne, Miller, Gavin J, White, Phil, Zhang, Ningli, Benoit, Michelle, Robertson, Karen, Merson, James R, Davis, Heather L, McCluskie, Michael J

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Aldehyde Oxidase: An Enzyme of Emerging Importance in Drug Discovery von Pryde, David C, Dalvie, Deepak, Hu, Qiyue, Jones, Peter, Obach, R. Scott, Tran, Thien-Duc

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Selection, Optimization, and Pharmacokinetic Properties of a Novel, Potent Antiviral Locked Nucleic Acid-Based Antisense Oligomer Targeting Hepatitis C Virus Internal Ribosome Entr... von LAXTON, Carl, BRADY, Kevin, MOSCHOS, Sterghios, TURNPENNY, Paul, RAWAL, Jaiessh, PRYDE, David C, SIDDERS, Ben, CORBAU, Romu, PICKFORD, Chris, MURRAY, E. J

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Alkali-metal mediated zincation of N-heterocyclic substrates using the lithium zincate complex, (THF)Li(TMP)Zn( tBu) 2 and applications in in situ cross coupling reactions von Blair, Victoria L., Blakemore, David C., Hay, Duncan, Hevia, Eva, Pryde, David C.

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A pharmacological master key mechanism that unlocks the selectivity filter gate in K⁺ channels von Schewe, Marcus, Sun, Han, Mert, Ümit, Mackenzie, Alexandra, Pike, Ashley C. W., Schulz, Friederike, Constantin, Cristina, Vowinkel, Kirsty S., Conrad, Linus J., Kiper, Aytug K., Gonzalez, Wendy, Musinszki, Marianne, Tegtmeier, Marie, Pryde, David C., Belabed, Hassane, Nazare, Marc, de Groot, Bert L., Decher, Niels, Fakler, Bernd, Carpenter, Elisabeth P., Tucker, Stephen J., Baukrowitz, Thomas

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Ion Channels as Therapeutic Targets: A Drug Discovery Perspective von Bagal, Sharan K, Brown, Alan D, Cox, Peter J, Omoto, Kiyoyuki, Owen, Robert M, Pryde, David C, Sidders, Benjamin, Skerratt, Sarah E, Stevens, Edward B, Storer, R. Ian, Swain, Nigel A

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An Imidazopiperidine Series of CCR5 Antagonists for the Treatment of HIV: The Discovery of N-{(1S)-1-(3-Fluorophenyl)-3-[(3-endo)-3-(5-isobutyryl-2-methyl-4,5,6,7-tetrahydro-1H-imi... von Stupple, Paul A, Batchelor, David V, Corless, Martin, Dorr, Patrick K, Ellis, David, Fenwick, David R, Galan, Sébastien R. G, Jones, Rhys M, Mason, Helen J, Middleton, Donald S, Perros, Manos, Perruccio, Francesca, Platts, Michelle Y, Pryde, David C, Rodrigues, Deborah, Smith, Nicholas N, Stephenson, Peter T, Webster, Robert, Westby, Mike, Wood, Anthony

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Valproic acid interactions with the NavMs voltage-gated sodium channel von Zanatta, Geancarlo, Sula, Altin, Miles, Andrew J., Ng, Leo C. T., Torella, Rubben, Pryde, David C., DeCaen, Paul G., Wallace, B. A.

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Practical synthetic routes to carbon-substituted nucleosides von Pryde, David C., Middleton, Donald S., Stephenson, Peter T., Wainwright, Philip, Maddaford, Adrian, Zhang, Xiurong, Leese, David, Glen, Rebecca, Hart, James, Forrest, Neil, Guyot, Thierry

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Design and Identification of a Novel, Functionally Subtype Selective GABAA Positive Allosteric Modulator (PF-06372865) von Owen, Robert M, Blakemore, David, Cao, Lishuang, Flanagan, Neil, Fish, Rebecca, Gibson, Karl R, Gurrell, Rachel, Huh, Chan Woo, Kammonen, Juha, Mortimer-Cassen, Elisabeth, Nickolls, Sarah A, Omoto, Kiyoyuki, Owen, Dafydd, Pike, Andy, Pryde, David C, Reynolds, David S, Roeloffs, Rosemarie, Rose, Colin, Stead, Clara, Takeuchi, Mifune, Warmus, Joseph S, Watson, Christine

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A Series of Potent CREBBP Bromodomain Ligands Reveals an Induced-Fit Pocket Stabilized by a Cation-π Interaction von Rooney, Timothy P. C., Filippakopoulos, Panagis, Fedorov, Oleg, Picaud, Sarah, Cortopassi, Wilian A., Hay, Duncan A., Martin, Sarah, Tumber, Anthony, Rogers, Catherine M., Philpott, Martin, Wang, Minghua, Thompson, Amber L., Heightman, Tom D., Pryde, David C., Cook, Andrew, Paton, Robert S., Müller, Susanne, Knapp, Stefan, Brennan, Paul E., Conway, Stuart J.

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Design and Identification of a Novel, Functionally Subtype Selective GABA A Positive Allosteric Modulator (PF-06372865) von Owen, Robert M, Blakemore, David, Cao, Lishuang, Flanagan, Neil, Fish, Rebecca, Gibson, Karl R, Gurrell, Rachel, Huh, Chan Woo, Kammonen, Juha, Mortimer-Cassen, Elisabeth, Nickolls, Sarah A, Omoto, Kiyoyuki, Owen, Dafydd, Pike, Andy, Pryde, David C, Reynolds, David S, Roeloffs, Rosemarie, Rose, Colin, Stead, Clara, Takeuchi, Mifune, Warmus, Joseph S, Watson, Christine

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Antiviral applications of Toll-like receptor agonists von Horscroft, Nigel J., Pryde, David C., Bright, Helen

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TRPA1 ankyrin repeat six interacts with a small molecule inhibitor chemotype von Tseng, Wei Chou, Pryde, David C., Yoger, Katrina E., Padilla, Karen M., Antonio, Brett M., Han, Seungil, Shanmugasundaram, Veerabahu, Gerlach, Aaron C.

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