Antiviral applications of Toll-like receptor agonists von Horscroft, Nigel J., Pryde, David C., Bright, Helen

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The discovery of a potent Nav1.3 inhibitor with good oral pharmacokinetics von Pryde, D C, Swain, NA, Stupple, P A, West, C W, Marron, B, Markworth, C J, Printzenhoff, D, Lin, Z, Cox, P J, Suzuki, R, McMurray, S, Waldron, G J, Payne, CE, Warmus, J S, Chapman, M L

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The discovery of a potent Na v 1.3 inhibitor with good oral pharmacokinetics von Pryde, D C, Swain, N A, Stupple, P A, West, C W, Marron, B, Markworth, C J, Printzenhoff, D, Lin, Z, Cox, P J, Suzuki, R, McMurray, S, Waldron, G J, Payne, C E, Warmus, J S, Chapman, M L

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The discovery of a potent series of carboxamide TRPA1 antagonists von Pryde, D. C., Marron, B., West, C. G., Reister, S., Amato, G., Yoger, K., Padilla, K., Turner, J., Swain, N. A., Cox, P. J., Skerratt, S. E., Ryckmans, T., Blakemore, D. C., Warmus, J., Gerlach, A. C.

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Ion Channels as Therapeutic Targets: A Drug Discovery Perspective von Bagal, Sharan K, Brown, Alan D, Cox, Peter J, Omoto, Kiyoyuki, Owen, Robert M, Pryde, David C, Sidders, Benjamin, Skerratt, Sarah E, Stevens, Edward B, Storer, R. Ian, Swain, Nigel A

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Site-selective Suzuki-Miyaura coupling of heteroaryl halides - understanding the trends for pharmaceutically important classes von Almond-Thynne, J, Blakemore, DC, Pryde, DC, Spivey, AC

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The discovery of a potent Nav1.3 inhibitor with good oral pharmacokineticsAll authors are, or were at the time of the work being undertaken, employees of Pfizer von Pryde, D. C, Swain, N. A, Stupple, P. A, West, C. W, Marron, B, Markworth, C. J, Printzenhoff, D, Lin, Z, Cox, P. J, Suzuki, R, McMurray, S, Waldron, G. J, Payne, C. E, Warmus, J. S, Chapman, M. L

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The discovery of a potent Nav1.3 inhibitor with good oral pharmacokinetics† †All authors are, or were at the time of the work being undertaken, employees of Pfizer von Pryde, D. C., Swain, N. A., Stupple, P. A., West, C. W., Marron, B., Markworth, C. J., Printzenhoff, D., Lin, Z., Cox, P. J., Suzuki, R., McMurray, S., Waldron, G. J., Payne, C. E., Warmus, J. S., Chapman, M. L.

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The discovery of a potent series of carboxamide TRPA1 antagonistsAll authors are either current or former employees of Pfizer.Electronic supplementary information (ESI) available:... von Pryde, D. C, Marron, B, West, C. G, Reister, S, Amato, G, Yoger, K, Padilla, K, Turner, J, Swain, N. A, Cox, P. J, Skerratt, S. E, Ryckmans, T, Blakemore, D. C, Warmus, J, Gerlach, A. C

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The discovery of a novel prototype small molecule TLR7 agonist for the treatment of hepatitis C virus infection von Pryde, David C., Tran, Thien-Duc, Jones, Peter, Parsons, Gemma C., Bish, Gerwyn, Adam, Fiona M., Smith, Mya C., Middleton, Donald S., Smith, Nick N., Calo, Frederick, Hay, Duncan, Paradowski, Michael, Proctor, Katie J. W., Parkinson, Tanya, Laxton, Carl, Fox, David N. A., Horscroft, Nigel J., Ciaramella, Giuseppe, Jones, Hannah M., Duckworth, Jonathan, Benson, Neil, Harrison, Anthony, Webster, Rob

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Analysis of differential efficacy and affinity of GABA(A) (alpha 1/alpha 2) selective modulators von Ain, QU, Owen, RM, Omoto, K, Torella, R, Bulusu, KC, Pryde, DC, Glen, RC, Fuchs, JE, Bender, A

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The Synthesis of Streptogramin Antibiotics: (−)-Griseoviridin and Its C-8 Epimer von Dvorak, Curt A., Schmitz, William D., Poon, Daniel J., Pryde, David C., Lawson, Jon P., Amos, Richard A., Meyers, Albert I.

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11th German Conference on Chemoinformatics (GCC 2015) : Fulda, Germany. 8-10 November 2015 von Torda, AE, Evers, A, Matter, H, Shea, J-E, Van den Broek, K, Kuhn, H, Truszkowski, A, Fraaije, JH, Bulusu, KC, Bender, A, Yosipof, A, Senderowitz, H, Schulz, R, Zimmermann, MO, Ruff, M, Heidrich, J, Onlia, I, Kirchner, B, Volkamer, A, Rippmann, F, Fulle, S, Saleh, N, Haensele, E, Whitley, DC, Bureau, R, Sandmann, A, Lanig, H, Hoffgaard, F, Frach, R, Rauh, D, Kohlbacher, O, Bodnarchuk, MS, Ross, GA, Husch, T, Schütter, C, Korth, M, Mbaze, LM, Simoben, CV, Lifongo, LL, Judson, P, Pisaková, H, Petrov, A, Pervov, VS, Achenbach, J, Renner, G, Schram, J, Fourches, D, Ibezim, A, Mbah, CJ, Adikwu, UM, Nwodo, NJ, Nagy, S, Baker, D, Dubrucq, K, Ain, QU, Owen, RM, Omoto, K, Spiwok, V, Firth, M, Bojarski, AJ, Naß, A, Hennig, S, Sievers-Engler, A, Böckler, FM, Montanari, F, Ecker, GF, Grebner, C, Ulander, J, Tyrchan, C, Kramer, C, Strohfeldt, S, Horinek, D, Rupp, B, Lisurek, M, Kühne, R, Mathea, M, Mohamad-Zobir, SZ, Fu, X, Fan, T-P, Polokoff, M, Ihlenfeldt, WD, Pretzel, J, Alhalabi, Z, Fraczkiewicz, R, Clark, RD, Kos, A, Himmler, H-J, Sticht, H, Dahlgren, M, Lin, T, Krilov, G, Abel, R, Sherman, W, Schomburg, KT, Jäger, C, Wieczorek, V, Westerhoff, LM, Buchholz, M, Mittal, S, Schmidt, TJ

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A concise enantioselective synthesis of a fully oxygen substituted ring A taxol precursor von Roy, Olivier, Pattenden, Gerald, Pryde, David C., Wilson, Claire

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The Discovery of Small Molecule Inhibitors of Neutral Endopeptidase. Structure-Activity Studies on Functionalized Glutaramides von Maw, Graham N., Stobie, Alan, Planken, Simon, Pryde, David C., Sanderson, Vivienne, Platts, Michelle Y., Corless, Martin, Stacey, Peter, Wayman, Christopher, Van Der Graaf, Piet, Kohl, Christopher, Coggon, Sara, Beaumont, Kevin

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Therapeutic Opportunities in Infectious Diseases: Highlights from the Society of Medicines Research Symposium, held on March 14th 2013 at the National Heart & Lung Institute, Londo... von Alderton, W.K., Anderson, R.J., Collingwood, S.P., Pryde, D.C.

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A Flexible, Efficient Synthesis of (±)-Carbocyclic Phosphonic Acid Nucleoside Derivatives von Wainwright, Phillip, Maddaford, Adrian, Bissell, Richard, Fisher, Ray, Leese, David, Lund, Andrew, Runcie, Karen, Dragovich, Peter S., Gonzalez, Javier, Kung, Pei-Pei, Middleton, Donald S., Pryde, David C., Stephenson, Peter T., Sutton, Scott C.

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Synthesis of 2-tetralones via a novel 1,2-carbonyl transposition of 1-tetralones von Pryde, David C, Henry, Steven S, Meyers, A.I

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A tandem radical macrocyclisation-transannular cyclisation approach towards the taxanes von Hitchcock, Stephen A., Houldsworth, Stephen J., Pattenden, Gerald, Pryde, David C., Thomson, Nicholas M., Blake, Alexander J.

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Studies towards the taxane ring system via a cascade macrocyclisation–transannulation strategy von Houldsworth, Stephen J., Pattenden, Gerald, Pryde, David C., Thomson, Nicholas M.

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