Non-Peptide GPIIb/IIIa Inhibitors. 20. Centrally Constrained Thienothiophene α-Sulfonamides Are Potent, Long Acting in Vivo Inhibitors of Platelet Aggregation von Egbertson, Melissa S, Cook, Jacquelynn J, Bednar, Bohumil, Prugh, John D, Bednar, Rodney A, Gaul, Stanley L, Gould, Robert J, Hartman, George D, Homnick, Carl F, Holahan, Marie A, Libby, Laura A, Lynch, Joseph J, Lynch, Robert J, Sitko, Gary R, Stranieri, Maria T, Vassallo, Laura M

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Nitric oxide production by rat bronchoalveolar macrophages or polymorphonuclear leukocytes following intratracheal instillation of lipopolysaccharide or silica von Huffman, L J, Prugh, D J, Millecchia, L, Schuller, K C, Cantrell, S, Porter, D W

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INFLUENCE OF HYPERTHYROIDISM ON RAT LUNG CYTOKINE PRODUCTION AND NUCLEAR FACTOR-κB ACTIVATION FOLLOWING OZONE EXPOSURE von Huffman, L. J., Prugh, D. J., Brumbaugh, K., Ding, M.

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Nonpeptide GPIIB/IIIA receptor antagonists. Part 21: C-6 flexibility and amide bond orientation are important factors in determining the affinity of compounds for activated or rest... von Egbertson, Melissa S, Bednar, Bohumil, Askew, Ben C, Bednar, Rodney A, Brashear, Karen, Breslin, Michael J, Duggan, Mark E, Fisher, Thorsten E, Halczenko, Wasyl, Hutchinson, John H, Ihle, Nathan, Prugh, John D, Wai, John S, Gould, Robert J, Hartman, George D

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Thieno[2,3-b]furan-2-sulfonamides as topical carbonic anhydrase inhibitors von Hartman, George D, Halczenko, Wasyl, Prugh, John D, Smith, Robert L, Sugrue, Michael F, Mallorga, Pierre, Michelson, Stuart R, Randall, William C, Schwam, Harvey, Sondey, John M

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New isomeric classes of topically active ocular hypotensive carbonic anhydrase inhibitors: 5-substituted thieno[2,3-b]thiophene-2-sulfonamides and 5-substituted thieno[3,2-b]thioph... von Prugh, John D, Hartman, George D, Mallorga, Pierre J, McKeever, Brian M, Michelson, Stuart R, Murcko, Mark A, Schwam, Harvey, Smith, Robert L, Sondey, John M

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3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 2. Structural modification of 7-(substituted aryl)-3,5-dihydroxy-6-heptenoic acids and their lactone derivatives von Hoffman, William F, Alberts, A. W, Cragoe, E. J, Deana, A. A, Evans, B. E, Gilfillan, J. L, Gould, N. P, Huff, J. W, Novello, F. C

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Nonpeptide GPIIB/IIIA inhibitors. 16. Thieno[2,3- b]thiophene α-sulfonamides are potent inhibitors of platelet aggregation von Prugh, John D., Gould, Robert J., Lynch, Robert J., Zhang, Guixiang, Cook, Jacquelynn J., Holahan, Marie A., Stranieri, Maria T., Sitko, Gary R., Lee Gaul, S., Bednar, Rodney A., Bednar, Bohumil, Hartman, George D.

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3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 6. trans-6-[2-(Substituted-1-naphthyl)ethyl(or ethenyl)]-3,4,5,6-tetrahydro-4-hydroxy-2H-pyran-2-ones von Prugh, John D, Alberts, Alfred W, Deana, Albert A, Gilfillian, James L, Huff, Jesse W, Smith, Robert L, Wiggins, J. Mark

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3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 1. Structural modification of 5-substituted 3,5-dihydroxypentanoic acids and their lactone derivatives von Stokker, G E, Hoffman, W F, Alberts, A W, Cragoe, Jr, E J, Deana, A A, Gilfillan, J L, Huff, J W, Novello, F C, Prugh, J D, Smith, R L

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Influence of hyperthyroidism on rat lung cytokine production and nuclear factor-kappaB activation following ozone exposure von Huffman, L J, Prugh, D J, Brumbaugh, K, Ding, M

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Influence of Hyperthyroidism on Rat Lung Cytokine Production and Nuclear Factor- B Activation Following Ozone Exposure von Huffman, L J, Prugh, D J, Brumbaugh, K, Ding, M

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3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 3. 7-(3,5-Disubstituted-[1,1'-biphenyl]-2-yl)-3,5-dihydroxy-6-heptenoic acids and their lactone derivatives von Stokker, G. E, Alberts, A. W, Anderson, P. S, Cragoe, E. J, Deana, A. A, Gilfillan, J. L, Hirshfield, J, Holtz, W. J, Hoffman, W. F

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A Convenient and Unambiguous Synthesis of 2 (or 7)-Chloronaphthalenes from Substituted α-Tetralones von Prugh, John D., Deana, Albert A., Wiggins, J. Mark

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Synthesis and utilization of the chiral synthon methyl 3-O-benzyl-2,4,6-trideoxy-6-iodo-.alpha.-D-erythro-hexopyranoside in the synthesis of a potent HMG-CoA reductase inhibitor von Prugh, John D, Rooney, C. Stanley, Deana, Albert A, Ramjit, Harri G

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Utilization of the chiral synthon, methyl 3-0-benzyl-2,4,6-trideoxy-6-iodo-α-D-erythro-hexopyranoside in the synthesis of a potent HMG-CoA reductase inhibitor von PRUGH, J. D, STANLEY ROONEY, C, DEANA, A. A, RAMJIT, H. G

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3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. I. Structural modification of 5-substituted 3,5-dihydroxypentanoic acids and their lactone derivatives von Stokker, G. E, Hoffman, W. F, Alberts, A. W, Cragoe, E. J, Deana, A. A, Gilfillan, J. L, Huff, J. W, Novello, F. C, Prugh, J. D

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Oxygenated chimpanzee metabolites of [(2-cyclopentyl-6,7-dichloro-2-methyl-1-oxo-5-indanyl)oxy]acetic acid (MK-473): their structural elucidation and synthesis von Prugh, John D, Smith, Robert L, Arison, Byron H, Smith, Graham M

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Non-Peptide GPIIb/IIIa Inhibitors. 20. Centrally Constrained Thienothiophene α-Sulfonamides Are Potent, Long Acting in Vivo Inhibitors of Platelet Aggregation von Egbertson, Melissa S, Cook, Jacquelynn J, Bednar, Bohumil, Prugh, John D, Bednar, Rodney A, Gaul, Stanley L, Gould, Robert J, Hartman, George D, Homnick, Carl F, Holahan, Marie A, Libby, Laura A, Lynch, Joseph J, Lynch, Robert J, Sitko, Gary R, Stranieri, Maria T

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Heterocyclic amines. 3. 3-Dimethylaminofuran von Prugh, J D, McCarthy, W C

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