Identification of an adeno-associated virus binding epitope for AVB sepharose affinity resin von Wang, Qiang, Lock, Martin, Prongay, Andrew J, Alvira, Mauricio R, Petkov, Boris, Wilson, James M

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Screening for Antiviral Inhibitors of the HIV Integrase–LEDGF/p75 Interaction Using the AlphaScreen™ Luminescent Proximity Assay von Hou, Yan, McGuinness, Debra E., Prongay, Andrew J., Feld, Boris, Ingravallo, Paul, Ogert, Robert A., Lunn, Charles A., Howe, John A.

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Potent inhibitors of HCV-NS3 protease derived from boronic acids von Venkatraman, Srikanth, Wu, Wanli, Prongay, Andrew, Girijavallabhan, Viyyoor, George Njoroge, F.

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Thermodynamics of Nucleotide and Inhibitor Binding to Wild-Type and Ispinesib-Resistant Forms of Human Kinesin Spindle Protein von Sheth, Payal R, Basso, Andrea, Duca, José S, Lesburg, Charles A, Ogas, Polina, Gray, Kimberly, Nale, Lissette, Mannarino, Anthony F, Prongay, Andrew J, Le, Hung V

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Discovery of the HCV NS3/4A Protease Inhibitor (1R,5S)-N-[3-Amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3- [2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl... von Prongay, Andrew J, Guo, Zhuyan, Yao, Nanhua, Pichardo, John, Fischmann, Thierry, Strickland, Corey, Myers, Joseph, Weber, Patricia C, Beyer, Brian M, Ingram, Richard, Hong, Zhi, Prosise, Winifred W, Ramanathan, Lata, Taremi, S. Shane, Yarosh-Tomaine, Taisa, Zhang, Rumin, Senior, Mary, Yang, Rong-Sheng, Malcolm, Bruce, Arasappan, Ashok, Bennett, Frank, Bogen, Stephane L, Chen, Kevin, Jao, Edwin, Liu, Yi-Tsung, Lovey, Raymond G, Saksena, Anil K, Venkatraman, Srikanth, Girijavallabhan, Viyyoor, Njoroge, F. George, Madison, Vincent

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Impact of Naturally Occurring Variants of HCV Protease on the Binding of Different Classes of Protease Inhibitors von Tong, Xiao, Guo, Zhuyan, Wright-Minogue, Jacquelyn, Xia, Ellen, Prongay, Andrew, Madison, Vincent, Qiu, Ping, Venkatraman, Srikanth, Velazquez, Francisco, Njoroge, F. George, Malcolm, Bruce A.

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Design and Synthesis of Depeptidized Macrocyclic Inhibitors of Hepatitis C NS3-4A Protease Using Structure-Based Drug Design von Venkatraman, Srikanth, Njoroge, F. George, Girijavallabhan, Viyyoor M, Madison, Vincent S, Yao, Nanua H, Prongay, Andrew J, Butkiewicz, Nancy, Pichardo, John

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Significant Differences in Capsid Properties and Potency Between Adeno-Associated Virus Vectors Produced in Sf9 and HEK293 Cells von Giles, April, Lock, Martin, Chen, Shu-Jen, Turner, Kevin, Wesolowski, Gregg, Prongay, Andrew, Petkov, Boris N., Olagbegi, Kanyin, Yan, Hanying, Wilson, James M.

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Novel inhibitors of hepatitis C NS3–NS4A serine protease derived from 2-aza-bicyclo[2.2.1]heptane-3-carboxylic acid von Venkatraman, Srikanth, Njoroge, F. George, Wu, Wanli, Girijavallabhan, Viyyoor, Prongay, Andrew J., Butkiewicz, Nancy, Pichardo, John

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Crystal structure of dimeric HIV-1 capsid protein von Momany, Cory, Kovari, Ladislau C., Prongay, Andrew J., Keller, Walter, Gitti, Rossitza K., Lee, Brian M., Gorbalenya, Alexander E., Tong, Liang, McClure, Jan, Ehrlich, Lorna S., Summers, Michael F., Carter, Carol, Rossmann, Michael G.

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Characterization of resistance mutations against HCV ketoamide protease inhibitors von Tong, Xiao, Bogen, Stephane, Chase, Robert, Girijavallabhan, V., Guo, Zhuyan, Njoroge, F. George, Prongay, Andrew, Saksena, Anil, Skelton, Angela, Xia, Ellen, Ralston, Robert

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Structural characterization of nitric oxide synthase isoforms reveals striking active-site conservation von Fischmann, Thierry O., Hruza, Alan, Niu, Xiao Da, Fossetta, James D., Lunn, Charles A., Dolphin, Edward, Prongay, Andrew J., Reichert, Paul, Lundell, Daniel J., Narula, Satwant K., Weber, Patricia C.

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90. Identification of an Adeno-Associated Virus Binding Epitope for AVB Sepharose Affinity Resin von Wang, Qiang, Lock, Martin, Prongay, Andrew, Alvira, Mauricio R., Petkov, Boris, Wilson, James M.

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Key steps in the structure-based optimization of the hepatitis C virus NS3/4A protease inhibitor SCH503034 von Madison, Vincent, Prongay, Andrew J., Guo, Zhuyan, Yao, Nanhua, Pichardo, John, Fischmann, Thierry, Strickland, Corey, Myers Jr, Joseph, Weber, Patricia C., Beyer, Brian M., Ingram, Richard, Hong, Zhi, Prosise, Winifred W., Ramanathan, Lata, Taremi, S. Shane, Yarosh-Tomaine, Taisa, Zhang, Rumin, Senior, Mary, Yang, Rong-Sheng, Malcolm, Bruce, Arasappan, Ashok, Bennett, Frank, Bogen, Stephane L., Chen, Kevin, Jao, Edwin, Liu, Yi-Tsung, Lovey, Raymond G., Saksena, Anil K., Venkatraman, Srikanth, Girijavallabhan, Viyyoor, Njoroge, F. George

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Mutations Conferring Resistance to SCH6, a Novel Hepatitis C Virus NS3/4A Protease Inhibitor von Yi, MinKyung, Tong, Xiao, Skelton, Angela, Chase, Robert, Chen, Tong, Prongay, Andrew, Bogen, Stephane L., Saksena, Anil K., Njoroge, F. George, Veselenak, Ronald L., Pyles, Richard B., Bourne, Nigel, Malcolm, Bruce A., Lemon, Stanley M.

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Thermodynamic and Structural Analysis of Phosphotyrosine Polypeptide Binding to Grb2-SH2 von McNemar, Charles, Snow, Mark E, Windsor, William T, Prongay, Andrew, Mui, Philip, Zhang, Rumin, Durkin, James, Le, Hung V, Weber, Patricia C

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Mutations conferring resistance to SCH6, a novel hepatitis C virus NS3/4A protease inhibitor. Reduced RNA replication fitness and partial rescue by second-site mutations von Yi, MinKyung, Tong, Xiao, Skelton, Angela, Chase, Robert, Chen, Tong, Prongay, Andrew, Bogen, Stephane L, Saksena, Anil K, Njoroge, F George, Veselenak, Ronald L, Pyles, Richard B, Bourne, Nigel, Malcolm, Bruce A, Lemon, Stanley M

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Discovery and Structure−Activity Relationship of P 1 −P 3 Ketoamide Derived Macrocyclic Inhibitors of Hepatitis C Virus NS3 Protease von Venkatraman, Srikanth, Velazquez, Francisco, Wu, Wanli, Blackman, Melissa, Chen, Kevin X., Bogen, Stephane, Nair, Latha, Tong, Xiao, Chase, Robert, Hart, Andrea, Agrawal, Sony, Pichardo, John, Prongay, Andrew, Cheng, Kuo-Chi, Girijavallabhan, Viyyoor, Piwinski, John, Shih, Neng-Yang, Njoroge, F. George

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Application of Ring-Closing Metathesis for the Synthesis of Macrocyclic Peptidomimetics as Inhibitors of HCV NS3 Protease von Velázquez, Francisco, Venkatraman, Srikanth, Wu, Wanli, Blackman, Melissa, Prongay, Andrew, Girijavallabhan, Viyyoor, Shih, Neng-Yang, Njoroge, F. George

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Second-Generation Highly Potent and Selective Inhibitors of the Hepatitis C Virus NS3 Serine Protease von Chen, Kevin X, Nair, Latha, Vibulbhan, Bancha, Yang, Weiying, Arasappan, Ashok, Bogen, Stephane L, Venkatraman, Srikanth, Bennett, Frank, Pan, Weidong, Blackman, Melissa L, Padilla, Angela I, Prongay, Andrew, Cheng, Kuo-Chi, Tong, Xiao, Shih, Neng-Yang, Njoroge, F. George

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