A Hybrid Mechanism of Action for BCL6 in B Cells Defined by Formation of Functionally Distinct Complexes at Enhancers and Promoters von Hatzi, Katerina, Jiang, Yanwen, Huang, Chuanxin, Garrett-Bakelman, Francine, Gearhart, Micah D., Giannopoulou, Eugenia G., Zumbo, Paul, Kirouac, Kevin, Bhaskara, Srividya, Polo, Jose M., Kormaksson, Matthias, MacKerell, Alexander D., Xue, Fengtian, Mason, Christopher E., Hiebert, Scott W., Prive, Gilbert G., Cerchietti, Leandro, Bardwell, Vivian J., Elemento, Olivier, Melnick, Ari

Volltext

Machine-Learning-Accelerated Perovskite Crystallization von Kirman, Jeffrey, Johnston, Andrew, Kuntz, Douglas A., Askerka, Mikhail, Gao, Yuan, Todorović, Petar, Ma, Dongxin, Privé, Gilbert G., Sargent, Edward H.

Volltext

Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells von Melnick, Ari, Polo, Jose M, Dell'Oso, Tania, Ranuncolo, Stella Maris, Cerchietti, Leandro, Beck, David, Da Silva, Gustavo F, Prive, Gilbert G, Licht, Jonathan D

Volltext

The integrated landscape of driver genomic alterations in glioblastoma von Frattini, Veronique, Trifonov, Vladimir, Chan, Joseph Minhow, Castano, Angelica, Lia, Marie, Abate, Francesco, Keir, Stephen T, Ji, Alan X, Zoppoli, Pietro, Niola, Francesco, Danussi, Carla, Dolgalev, Igor, Porrati, Paola, Pellegatta, Serena, Heguy, Adriana, Gupta, Gaurav, Pisapia, David J, Canoll, Peter, Bruce, Jeffrey N, McLendon, Roger E, Yan, Hai, Aldape, Ken, Finocchiaro, Gaetano, Mikkelsen, Tom, Privé, Gilbert G, Bigner, Darell D, Lasorella, Anna, Rabadan, Raul, Iavarone, Antonio

Volltext

Ubiquitylome analysis identifies dysregulation of effector substrates in SPOP-mutant prostate cancer von Theurillat, Jean-Philippe P., Udeshi, Namrata D., Errington, Wesley J., Svinkina, Tanya, Baca, Sylvan C., Pop, Marius, Wild, Peter J., Blattner, Mirjam, Groner, Anna C., Rubin, Mark A., Moch, Holger, Privé, Gilbert G., Carr, Steven A., Garraway, Levi A.

Volltext

Detergents for the stabilization and crystallization of membrane proteins von Privé, Gilbert G.

Volltext

Higher-order oligomerization promotes localization of SPOP to liquid nuclear speckles von Marzahn, Melissa R, Marada, Suresh, Lee, Jihun, Nourse, Amanda, Kenrick, Sophia, Zhao, Huaying, Ben-Nissan, Gili, Kolaitis, Regina-Maria, Peters, Jennifer L, Pounds, Stanley, Errington, Wesley J, Privé, Gilbert G, Taylor, J Paul, Sharon, Michal, Schuck, Peter, Ogden, Stacey K, Mittag, Tanja

Volltext

A Small-Molecule Inhibitor of BCL6 Kills DLBCL Cells In Vitro and In Vivo von Cerchietti, Leandro C., Ghetu, Alexandru F., Zhu, Xiao, Da Silva, Gustavo F., Zhong, Shijun, Matthews, Marilyn, Bunting, Karen L., Polo, Jose M., Farès, Christophe, Arrowsmith, Cheryl H., Yang, Shao Ning, Garcia, Monica, Coop, Andrew, MacKerell, Alexander D., Privé, Gilbert G., Melnick, Ari

Volltext

Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export von Heybrock, Saskia, Kanerva, Kristiina, Meng, Ying, Ing, Chris, Liang, Anna, Xiong, Zi-Jian, Weng, Xialian, Ah Kim, Young, Collins, Richard, Trimble, William, Pomès, Régis, Privé, Gilbert G., Annaert, Wim, Schwake, Michael, Heeren, Joerg, Lüllmann-Rauch, Renate, Grinstein, Sergio, Ikonen, Elina, Saftig, Paul, Neculai, Dante

Volltext

Proteomics-Based Comparative Mapping of the Secretomes of Human Brown and White Adipocytes Reveals EPDR1 as a Novel Batokine von Deshmukh, Atul S, Peijs, Lone, Beaudry, Jacqueline L, Jespersen, Naja Z, Nielsen, Carsten H, Ma, Tao, Brunner, Andreas D, Larsen, Therese J, Bayarri-Olmos, Rafael, Prabhakar, Bhargav S, Helgstrand, Charlotte, Severinsen, Mai C K, Holst, Birgitte, Kjaer, Andreas, Tang-Christensen, Mads, Sanfridson, Annika, Garred, Peter, Privé, Gilbert G, Pedersen, Bente K, Gerhart-Hines, Zachary, Nielsen, Søren, Drucker, Daniel J, Mann, Matthias, Scheele, Camilla

Volltext

Crystal structure of KLHL3 in complex with Cullin3 von Ji, Alan X, Privé, Gilbert G

Volltext

Adaptor Protein Self-Assembly Drives the Control of a Cullin-RING Ubiquitin Ligase von Errington, Wesley J., Khan, M. Qasim, Bueler, Stephanie A., Rubinstein, John L., Chakrabartty, Avijit, Privé, Gilbert G.

Volltext

Critical Residues within the BTB Domain of PLZF and Bcl-6 Modulate Interaction with Corepressors von Melnick, Ari, Carlile, Graeme, Ahmad, K. Farid, Kiang, Chih-Li, Corcoran, Connie, Bardwell, Vivian, Prive, Gilbert G., Licht, Jonathan D.

Volltext

TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate von Venturutti, Leandro, Teater, Matt, Zhai, Andrew, Chadburn, Amy, Babiker, Leena, Kim, Daleum, Béguelin, Wendy, Lee, Tak C., Kim, Youngjun, Chin, Christopher R., Yewdell, William T., Raught, Brian, Phillip, Jude M., Jiang, Yanwen, Staudt, Louis M., Green, Michael R., Chaudhuri, Jayanta, Elemento, Olivier, Farinha, Pedro, Weng, Andrew P., Nissen, Michael D., Steidl, Christian, Morin, Ryan D., Scott, David W., Privé, Gilbert G., Melnick, Ari M.

Volltext

Structure of Human Acid Sphingomyelinase Reveals the Role of the Saposin Domain in Activating Substrate Hydrolysis von Xiong, Zi-Jian, Huang, Jingjing, Poda, Gennady, Pomès, Régis, Privé, Gilbert G.

Volltext

Fungal-Selective Resorcylate Aminopyrazole Hsp90 Inhibitors: Optimization of Whole-Cell Anticryptococcal Activity and Insights into the Structural Origins of Cryptococcal Selectivi... von Marcyk, Paul T, LeBlanc, Emmanuelle V, Kuntz, Douglas A, Xue, Alice, Ortiz, Francisco, Trilles, Richard, Bengtson, Stephen, Kenney, Tristan M. G, Huang, David S, Robbins, Nicole, Williams, Noelle S, Krysan, Damian J, Privé, Gilbert G, Whitesell, Luke, Cowen, Leah E, Brown, Lauren E

Volltext

Picodiscs for Facile Protein-Glycolipid Interaction Analysis von Leney, Aneika C, Rezaei Darestani, Reza, Li, Jun, Nikjah, Sanaz, Kitova, Elena N, Zou, Chunxia, Cairo, Christopher W, Xiong, Zi Jian, Privé, Gilbert G, Klassen, John S

Volltext

Characterizing the Size and Composition of Saposin A Lipoprotein Picodiscs von Li, Jun, Richards, Michele R., Bagal, Dhanashri, Campuzano, Iain D. G., Kitova, Elena N., Xiong, Zi Jian, Privé, Gilbert G., Klassen, John S.

Volltext

Screening Glycolipids Against Proteins in Vitro Using Picodiscs and Catch-and-Release Electrospray Ionization-Mass Spectrometry von Li, Jun, Fan, Xuxin, Kitova, Elena N, Zou, Chunxia, Cairo, Christopher W, Eugenio, Luiz, Ng, Kenneth K. S, Xiong, Zi Jian, Privé, Gilbert G, Klassen, John S

Volltext

Structural Insights into KCTD Protein Assembly and Cullin3 Recognition von Ji, Alan X., Chu, Anh, Nielsen, Tine Kragh, Benlekbir, Samir, Rubinstein, John L., Privé, Gilbert G.

Volltext