Differential reprogramming of breast cancer subtypes in 3D cultures and implications for sensitivity to targeted therapy von Koedoot, Esmee, Wolters, Liesanne, Smid, Marcel, Stoilov, Peter, Burger, Gerhard A., Herpers, Bram, Yan, Kuan, Price, Leo S., Martens, John W. M., Le Dévédec, Sylvia E., van de Water, Bob

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3D imaging of colorectal cancer organoids identifies responses to Tankyrase inhibitors von Badder, Luned M, Hollins, Andrew J, Herpers, Bram, Yan, Kuan, Ewan, Kenneth B, Thomas, Mairian, Shone, Jennifer R, Badder, Delyth A, Naven, Marc, Ashelford, Kevin E, Hargest, Rachel, Clarke, Alan R, Esdar, Christina, Buchstaller, Hans-Peter, Treherne, J. Mark, Boj, Sylvia, Ramezanpour, Bahar, Wienke, Dirk, Price, Leo S, Shaw, Paul H, Dale, Trevor C

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A 3D human co-culture to model neuron-astrocyte interactions in tauopathies von Batenburg, Kevin L, Sestito, Claudia, Cornelissen-Steijger, Paulien, van Weering, Jan R T, Price, Leo S, Heine, Vivi M, Scheper, Wiep

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Ultra high content image analysis and phenotype profiling of 3D cultured micro-tissues von Di, Zi, Klop, Maarten J D, Rogkoti, Vasiliki-Maria, Le Dévédec, Sylvia E, van de Water, Bob, Verbeek, Fons J, Price, Leo S, Meerman, John H N

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Epac-Rap Signaling Reduces Oxidative Stress in the Tubular Epithelium von STOKMAN, Geurt, YU QIN, VAN DE WATER, Bob, KOK, Robbert J, PRICE, Leo S, BOOIJ, Tijmen H, RAMAIAHGARI, Sreenivasa, LACOMBE, Marie, DOLMAN, M. Emmy M, VAN DORENMALEN, Kim M. A, TESKE, Gwendoline J. D, FLORQUIN, Sandrine, SCHWEDE, Frank

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Rap1 Regulates E-cadherin-mediated Cell-Cell Adhesion von Price, Leo S, Hajdo-Milasinovic, Amra, Zhao, Jun, Zwartkruis, Fried J T, Collard, John G, Bos, Johannes L

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Hydrophilic Auristatin Glycoside Payload Enables Improved Antibody-Drug Conjugate Efficacy and Biocompatibility von Satomaa, Tero, Pynnönen, Henna, Vilkman, Anja, Kotiranta, Titta, Pitkänen, Virve, Heiskanen, Annamari, Herpers, Bram, Price, Leo, Helin, Jari, Saarinen, Juhani

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Spatial Regulation of Cyclic AMP-Epac1 Signaling in Cell Adhesion by ERM Proteins von Gloerich, Martijn, Ponsioen, Bas, Vliem, Marjolein J., Zhang, Zhongchun, Zhao, Jun, Kooistra, Matthijs R., Price, Leo S., Ritsma, Laila, Zwartkruis, Fried J., Rehmann, Holger, Jalink, Kees, Bos, Johannes L.

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Prioritization of novel ADPKD drug candidates from disease-stage specific gene expression profiles von Malas, Tareq B., Leonhard, Wouter N., Bange, Hester, Granchi, Zoraide, Hettne, Kristina M., Van Westen, Gerard J.P., Price, Leo S., 't Hoen, Peter A.C., Peters, Dorien J.M.

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Calcium Signaling Regulates Translocation and Activation of Rac von Price, Leo S., Langeslag, Michiel, Klooster, Jean Paul ten, Hordijk, Peter L., Jalink, Kees, Collard, John G.

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Screening out irrelevant cell-based models of disease von Horvath, Peter, Aulner, Nathalie, Bickle, Marc, Davies, Anthony M., Nery, Elaine Del, Ebner, Daniel, Montoya, Maria C., Östling, Päivi, Pietiäinen, Vilja, Price, Leo S., Shorte, Spencer L., Turcatti, Gerardo, von Schantz, Carina, Carragher, Neil O.

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Activation of Rac and Cdc42 by integrins mediates cell spreading von Price, L S, Leng, J, Schwartz, M A, Bokoch, G M

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3D Cell-Based Assays for Drug Screens: Challenges in Imaging, Image Analysis, and High-Content Analysis von Booij, Tijmen H., Price, Leo S., Danen, Erik H. J.

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A 3D in vitro model of differentiated HepG2 cell spheroids with improved liver-like properties for repeated dose high-throughput toxicity studies von Ramaiahgari, Sreenivasa C., den Braver, Michiel W., Herpers, Bram, Terpstra, Valeska, Commandeur, Jan N. M., van de Water, Bob, Price, Leo S.

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Focal Adhesion Kinase Signaling Mediates Acute Renal Injury Induced by Ischemia/Reperfusion von Qin, Yu, Alderliesten, Maaike C, Stokman, Geurt, Pennekamp, Petra, Bonventre, Joseph V, de Heer, Emile, Ichimura, Takaharu, de Graauw, Marjo, Price, Leo S, van de Water, Bob

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Renal expression of exchange protein directly activated by cAMP (Epac) 1 and 2 von Li, Yuedan, Konings, Irene B. M, Zhao, Jun, Price, Leo S, de Heer, Emile, Deen, Peter M. T

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Focal Adhesion Kinase Mediates the Integrin Signaling Requirement for Growth Factor Activation of MAP Kinase von Renshaw, Mark W., Price, Leo S., Schwartz, Martin Alexander

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Combining Doublecortin-Like Kinase Silencing and Vinca Alkaloids Results in a Synergistic Apoptotic Effect in Neuroblastoma Cells von Verissimo, Carla S., Cheng, Sou, Puigvert, Jordi C., Qin, Yu, Vroon, Anne, van Deutekom, Judith, Price, Leo S., Danen, Erik H.J., van de Water, Bob, Fitzsimons, Carlos P., Vreugdenhil, Erno

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AF6 Negatively Regulates Rap1-induced Cell Adhesion von Zhang, Zhongchun, Rehmann, Holger, Price, Leo S., Riedl, Jurgen, Bos, Johannes L.

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Renal cyst growth is attenuated by a combination treatment of tolvaptan and pioglitazone, while pioglitazone treatment alone is not effective von Kanhai, Anish A., Bange, Hester, Verburg, Lotte, Dijkstra, Kyra L., Price, Leo S., Peters, Dorien J. M., Leonhard, Wouter N.

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