Vismodegib Exerts Targeted Efficacy Against Recurrent Sonic Hedgehog-Subgroup Medulloblastoma: Results From Phase II Pediatric Brain Tumor Consortium Studies PBTC-025B and PBTC-032 von Robinson, Giles W, Orr, Brent A, Wu, Gang, Gururangan, Sridharan, Lin, Tong, Qaddoumi, Ibrahim, Packer, Roger J, Goldman, Stewart, Prados, Michael D, Desjardins, Annick, Chintagumpala, Murali, Takebe, Naoko, Kaste, Sue C, Rusch, Michael, Allen, Sariah J, Onar-Thomas, Arzu, Stewart, Clinton F, Fouladi, Maryam, Boyett, James M, Gilbertson, Richard J, Curran, Tom, Ellison, David W, Gajjar, Amar

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Bevacizumab Alone and in Combination With Irinotecan in Recurrent Glioblastoma von Friedman, Henry S, Prados, Michael D, Wen, Patrick Y, Mikkelsen, Tom, Schiff, David, Abrey, Lauren E, Yung, W K Alfred, Paleologos, Nina, Nicholas, Martin K, Jensen, Randy, Vredenburgh, James, Huang, Jane, Zheng, Maoxia, Cloughesy, Timothy

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Current Strategies for Management of Medulloblastoma von Prados, Michael D

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Role of Extent of Resection in the Long-Term Outcome of Low-Grade Hemispheric Gliomas von SMITH, Justin S, CHANG, Edward F, LAMBORN, Kathleen R, CHANG, Susan M, PRADOS, Michael D, CHA, Soonmee, TIHAN, Tarik, VANDENBERG, Scott, MCDERMOTT, Michael W, BERGER, Mitchel S

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Pharmacologic inhibition of cyclin-dependent kinases 4 and 6 arrests the growth of glioblastoma multiforme intracranial xenografts von Michaud, Karine, Solomon, David A, Oermann, Eric, Kim, Jung-Sik, Zhong, Wei-Zhu, Prados, Michael D, Ozawa, Tomoko, James, C David, Waldman, Todd

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Toward precision medicine in glioblastoma: the promise and the challenges von Prados, Michael D, Byron, Sara A, Tran, Nhan L, Phillips, Joanna J, Molinaro, Annette M, Ligon, Keith L, Wen, Patrick Y, Kuhn, John G, Mellinghoff, Ingo K, de Groot, John F, Colman, Howard, Cloughesy, Timothy F, Chang, Susan M, Ryken, Timothy C, Tembe, Waibhav D, Kiefer, Jeffrey A, Berens, Michael E, Craig, David W, Carpten, John D, Trent, Jeffrey M

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Evidence for Sequenced Molecular Evolution of IDH1 Mutant Glioblastoma From a Distinct Cell of Origin von LAI, Albert, KHARBANDA, Samir, ELLINGSON, Benjamin M, BOWERS, Chauncey W, SORIANO, Robert H, SCHMIDT, Nils O, MOHAN, Sankar, YONG, William H, SESHAGIRI, Somasekar, MODRUSAN, Zora, ZHAOSHI JIANG, ALDAPE, Kenneth D, POPE, Whitney B, MISCHEL, Paul S, LIAU, Linda M, ESCOVEDO, Cameron J, WEIDONG CHEN, PHIOANH LEIA NGHIEMPHU, DAVID JAMES, C, PRADOS, Michael D, WESTPHAL, Manfred, LAMSZUS, Katrin, CLOUGHESY, Timothy, TRAN, Anh, PHILLIPS, Heidi S, SOLIS, Orestes E, PEALE, Franklin, FORREST, William F, PUJARA, Kanan, CARRILLO, Jose A, PANDITA, Ajay

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Heat-shock protein peptide complex-96 vaccination for recurrent glioblastoma: a phase II, single-arm trial von Bloch, Orin, Crane, Courtney A, Fuks, Yelena, Kaur, Rajwant, Aghi, Manish K, Berger, Mitchel S, Butowski, Nicholas A, Chang, Susan M, Clarke, Jennifer L, McDermott, Michael W, Prados, Michael D, Sloan, Andrew E, Bruce, Jeffrey N, Parsa, Andrew T

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An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR-dependent pathway von Guo, Deliang, Reinitz, Felicia, Youssef, Mary, Hong, Cynthia, Nathanson, David, Akhavan, David, Kuga, Daisuke, Amzajerdi, Ali Nael, Soto, Horacio, Zhu, Shaojun, Babic, Ivan, Tanaka, Kazuhiro, Dang, Julie, Iwanami, Akio, Gini, Beatrice, Dejesus, Jason, Lisiero, Dominique D, Huang, Tiffany T, Prins, Robert M, Wen, Patrick Y, Robins, H Ian, Prados, Michael D, Deangelis, Lisa M, Mellinghoff, Ingo K, Mehta, Minesh P, James, C David, Chakravarti, Arnab, Cloughesy, Timothy F, Tontonoz, Peter, Mischel, Paul S

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Phase II Study of Erlotinib Plus Temozolomide During and After Radiation Therapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma von PRADOS, Michael D, CHANG, Susan M, FEDOROFF, Anne, SNEED, Penny K, BERGER, Mitchel S, MCDERMOTT, Michael W, PARSA, Andrew T, VANDENBERG, Scott, JAMES, C. David, LAMBORN, Kathleen R, STOKOE, David, HAAS-KOGAN, Daphne A, BUTOWSKI, Nicholas, DEBOER, Rebecca, PARVATANENI, Rupa, CARLINER, Hannah, KABUUBI, Paul, AYERS-RINGLER, Jennifer, RABBITT, Jane, PAGE, Margaretta

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Phase II Study of Aflibercept in Recurrent Malignant Glioma: A North American Brain Tumor Consortium Study von DE GROOT, John F, LAMBORN, Kathleen R, MEHTA, Minesh P, LASSMAN, Andrew B, DEANGELIS, Lisa M, YUNG, W. K. Alfred, CHEN, Alice, PRADOS, Michael D, WEN, Patrick Y, CHANG, Susan M, GILBERT, Mark R, CLOUGHESY, Timothy F, ALDAPE, Kenneth, JUN YAO, JACKSON, Edward F, LIEBERMAN, Frank, ROBINS, H. Ian

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Epidermal Growth Factor Receptor, Protein Kinase B/Akt, and Glioma Response to Erlotinib von Haas-Kogan, Daphne A., Prados, Michael D., Tihan, Tarik, Eberhard, David A., Jelluma, Nannette, Arvold, Nils D., Baumber, Rachel, Lamborn, Kathleen R., Kapadia, Ami, Malec, Mary, Berger, Mitchel S., Stokoe, David

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Direct Intracerebral Delivery of Cintredekin Besudotox (IL13-PE38QQR) in Recurrent Malignant Glioma: A Report by the Cintredekin Besudotox Intraparenchymal Study Group von KUNWAR, Sandeep, PRADOS, Michael D, ALDAPE, Kenneth D, CROTEAU, David J, SHERMAN, Jeffrey W, PURI, Raj K, CHANG, Susan M, BERGER, Mitchel S, LANG, Frederick F, PIEPMEIER, Joseph M, SAMPSON, John H, RAM, Zvi, GUTIN, Philip H, GIBBONS, Robert D

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EGFR signaling through an Akt-SREBP-1-dependent, rapamycin-resistant pathway sensitizes glioblastomas to antilipogenic therapy von Guo, Deliang, Prins, Robert M, Dang, Julie, Kuga, Daisuke, Iwanami, Akio, Soto, Horacio, Lin, Kelly Y, Huang, Tiffany T, Akhavan, David, Hock, M Benjamin, Zhu, Shaojun, Kofman, Ava A, Bensinger, Steve J, Yong, William H, Vinters, Harry V, Horvath, Steve, Watson, Andrew D, Kuhn, John G, Robins, H Ian, Mehta, Minesh P, Wen, Patrick Y, DeAngelis, Lisa M, Prados, Michael D, Mellinghoff, Ingo K, Cloughesy, Timothy F, Mischel, Paul S

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Targeting Wee1 for the treatment of pediatric high-grade gliomas von Mueller, Sabine, Hashizume, Rintaro, Yang, Xiaodong, Kolkowitz, Ilan, Olow, Aleksandra K, Phillips, Joanna, Smirnov, Ivan, Tom, Maxwell W, Prados, Michael D, James, C David, Berger, Mitchel S, Gupta, Nalin, Haas-Kogan, Daphne A

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Progression-free survival: an important end point in evaluating therapy for recurrent high-grade gliomas von Lamborn, Kathleen R, Yung, W K Alfred, Chang, Susan M, Wen, Patrick Y, Cloughesy, Timothy F, DeAngelis, Lisa M, Robins, H Ian, Lieberman, Frank S, Fine, Howard A, Fink, Karen L, Junck, Larry, Abrey, Lauren, Gilbert, Mark R, Mehta, Minesh, Kuhn, John G, Aldape, Kenneth D, Hibberts, Janelle, Peterson, Pamela M, Prados, Michael D

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Preoperative prognostic classification system for hemispheric low-grade gliomas in adults von Chang, Edward F, Smith, Justin S, Chang, Susan M, Lamborn, Kathleen R, Prados, Michael D, Butowski, Nicholas, Barbaro, Nicholas M, Parsa, Andrew T, Berger, Mitchel S, McDermott, Michael M

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Mass cytometry detects H3.3K27M-specific vaccine responses in diffuse midline glioma von Mueller, Sabine, Taitt, Jared M, Villanueva-Meyer, Javier E, Bonner, Erin R, Nejo, Takahide, Lulla, Rishi R, Goldman, Stewart, Banerjee, Anu, Chi, Susan N, Whipple, Nicholas S, Crawford, John R, Gauvain, Karen, Nazemi, Kellie J, Watchmaker, Payal B, Almeida, Neil D, Okada, Kaori, Salazar, Andres M, Gilbert, Ryan D, Nazarian, Javad, Molinaro, Annette M, Butterfield, Lisa H, Prados, Michael D, Okada, Hideho

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Clinical outcome and prognostic factors for central neurocytoma: twenty year institutional experience von Imber, Brandon S., Braunstein, Steve E., Wu, Fred Y., Nabavizadeh, Nima, Boehling, Nicholas, Weinberg, Vivian K., Tihan, Tarik, Barnes, Michael, Mueller, Sabine, Butowski, Nicholas A., Clarke, Jennifer L., Chang, Susan M., McDermott, Michael M., Prados, Michael D., Berger, Mitchel S., Haas-Kogan, Daphne A.

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Epidermal Growth Factor Receptor Variant III Status Defines Clinically Distinct Subtypes of Glioblastoma von PELLOSKI, Christopher E, BALLMAN, Karla V, WOO, Shiao Y, HEIMBERGER, Amy B, SUKI, Dima, PRADOS, Michael D, CHANG, Susan M, BARKER, Fred G, BUCKNER, Jan C, JAMES, C. David, ALDAPE, Kenneth, FURTH, Alfred F, LI ZHANG, LIN, E, SULMAN, Erik P, BHAT, Krishna, MCDONALD, J. Matthew, YUNG, W. K. Alfred, COLMAN, Howard

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