Clinical validation of a next-generation sequencing-based multi-cancer early detection "liquid biopsy" blood test in over 1,000 dogs using an independent testing set: The CANcer De... von Flory, Andi, Kruglyak, Kristina M, Tynan, John A, McLennan, Lisa M, Rafalko, Jill M, Fiaux, Patrick Christian, Hernandez, Gilberto E, Marass, Francesco, Nakashe, Prachi, Ruiz-Perez, Carlos A, Fath, Donna M, Jennings, Thuy, Motalli-Pepio, Rita, Wotrang, Kate, McCleary-Wheeler, Angela L, Lana, Susan, Phillips, Brenda, Flesner, Brian K, Leibman, Nicole F, LaDue, Tracy, Tripp, Chelsea D, Coomber, Brenda L, Woods, J Paul, Miller, Mairin, Aiken, Sean W, Wolf-Ringwall, Amber, Borgatti, Antonella, Kraska, Kathleen, Thomson, Christopher B, Kosanovich Cahalane, Alane, Murray, Rebecca L, Kisseberth, William C, Camps-Palau, Maria A, Floch, Franck, Beaudu-Lange, Claire, Klajer-Peres, Aurélia, Keravel, Olivier, Fribourg-Blanc, Luc-André, Mazetier, Pascale Chicha, Marco, Angelo, McLeod, Molly B, Portillo, Erin, Clark, Terry S, Judd, Scott, Feinberg, C Kirk, Benitez, Marie, Runyan, Candace, Hackett, Lindsey, Lafey, Scott, Richardson, Danielle, Vineyard, Sarah, Tefend Campbell, Mary, Dharajiya, Nilesh, Jensen, Taylor J, van den Boom, Dirk, Diaz, Jr, Luis A, Grosu, Daniel S, Polk, Arthur, Marsal, Kalle, Hicks, Susan Cho, Lytle, Katherine M, Holtvoigt, Lauren, Chibuk, Jason, Chorny, Ilya, Tsui, Dana W Y

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Cycling Transcriptional Networks Optimize Energy Utilization on a Genome Scale von Wang, Guang-Zhong, Hickey, Stephanie L., Shi, Lei, Huang, Hung-Chung, Nakashe, Prachi, Koike, Nobuya, Tu, Benjamin P., Takahashi, Joseph S., Konopka, Genevieve

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ChIP-seq and RNA-seq methods to study circadian control of transcription in mammals von Takahashi, Joseph S, Kumar, Vivek, Nakashe, Prachi, Koike, Nobuya, Huang, Hung-Chung, Green, Carla B, Kim, Tae-Kyung

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The monomeric state of the proton‐coupled folate transporter represents the functional unit in the plasma membrane von Duddempudi, Phaneendra K., Nakashe, Prachi, Blanton, Michael P., Jansen, Michaela

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Proof-of-concept evaluation of next-generation sequencing-based liquid biopsy for non-invasive cancer detection in cats von Ruiz-Perez, Carlos A, Nakashe, Prachi, Marshall, Maggie A, Marass, Francesco, Tang, Tuong, McLennan, Lisa M, Kroll, Marissa, Flesner, Brian K, Gray, Suzanne, Rafalko, Jill M, Grosu, Daniel S, Hicks, Susan C, Tynan, John A, Tsui, Dana W Y, Flory, Andi, Kruglyak, Kristina M

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Blood-Based Liquid Biopsy for Comprehensive Cancer Genomic Profiling Using Next-Generation Sequencing: An Emerging Paradigm for Non-invasive Cancer Detection and Management in Dogs von Kruglyak, Kristina M., Chibuk, Jason, McLennan, Lisa, Nakashe, Prachi, Hernandez, Gilberto E., Motalli-Pepio, Rita, Fath, Donna M., Tynan, John A., Holtvoigt, Lauren E., Chorny, Ilya, Grosu, Daniel S., Tsui, Dana W. Y., Flory, Andi

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Genome-wide sequencing of cell-free DNA identifies copy number alterations that can be used for monitoring response to immunotherapy in cancer patients von Jensen, Taylor J, Goodman, Aaron M, Kato, Shumei, Ellison, Christopher K, Daniels, Gregory A, Kim, Lisa, Nakashe, Prachi, McCarthy, Erin, Mazloom, Amin R, McLennan, Graham, Grosu, Daniel S, Ehrich, Mathias, Kurzrock, Razelle

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Analysis of the Oligomeric State of Surface-Localized Proton-Coupled Folate Transporter by Blue Native Polyacrylamide Gel Electrophoresis von Nakashe, Prachi, Jansen, Michaela

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Comparative oncology analysis using genomic profiling of canine cancers by tissue and liquid biopsy testing reveals actionable somatic alterations with orthologs in human cancers von Tsui, Dana, Chorny, Ilya, Kruglyak, Kristina M, Tynan, John A., Hernandez, Gilberto E, Nakashe, Prachi, Hicks, Susan Cho, Motalli-Pepio, Rita, McLennan, Lisa M., Holtvoigt, Lauren E., Rafalko, Jill M., Chibuk, Jason, McCleary-Wheeler, Angela L., Flory, Andi, Grosu, Daniel S.

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Development of an NGS assay to detect MRD in hematologic malignancies von Yu, James, Sitlani, Parth, Nakashe, Prachi, Sims, Gregory, Scott, Christopher, Graber, Armin, Falk, Jeffrey

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Genome-wide Sequencing of Cell-free DNA Enables Detection of Copy-number Alterations in Patients with Cancer Where Tissue Biopsy is Not Feasible von Jensen, Taylor J., Goodman, Aaron M., Ellison, Christopher K., Holden, Kimberly A., Kato, Shumei, Kim, Lisa, Daniels, Gregory A., Fitzgerald, Kerry, McCarthy, Erin, Nakashe, Prachi, Mazloom, Amin R., Almasri, Eyad, McLennan, Graham, Grosu, Daniel S., Eisenberg, Marcia, Kurzrock, Razelle

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Abstract 1362: Genome-wide sequencing of cell-free DNA enables detection of copy number alterations in cancer patients where tissue biopsy is not feasible von Jensen, Taylor J., Goodman, Aaron M., Kato, Shumei, Ellison, Christopher K., Kelly, Kimberly, Kim, Lisa, Daniels, Gregory A., Fitzgerald, Kerry, McCarthy, Erin, Nakashe, Prachi, Mazloom, Amin R., McLennan, Graham, Almasri, Eyad, Grosu, Daniel S., Eisenberg, Marcia, Kurzrock, Razelle

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Clinical validation of a next-generation sequencing-based multi-cancer early detection "liquid biopsy" blood test in over 1,000 dogs using an independent testing set: The CANcer De... von Flory, Andi, Kruglyak, Kristina M, Tynan, John A, McLennan, Lisa M, Rafalko, Jill M, Fiaux, Patrick Christian, Hernandez, Gilberto E, Marass, Francesco, Nakashe, Prachi, Ruiz-Perez, Carlos A, Fath, Donna M, Jennings, Thuy, Motalli-Pepio, Rita, Wotrang, Kate, McCleary-Wheeler, Angela L, Lana, Susan, Phillips, Brenda, Flesner, Brian K, Leibman, Nicole F, LaDue, Tracy, Tripp, Chelsea D, Coomber, Brenda L, Woods, J. Paul, Miller, Mairin, Aiken, Sean W, Wolf-Ringwall, Amber, Borgatti, Antonella, Kraska, Kathleen, Thomson, Christopher B, Kosanovich Cahalane, Alane, Murray, Rebecca L, Kisseberth, William C, Camps-Palau, Maria A, Floch, Franck, Beaudu-Lange, Claire, Klajer-Peres, Aurélia, Keravel, Olivier, Fribourg-Blanc, Luc-André, Mazetier, Pascale Chicha, Marco, Angelo, McLeod, Molly B, Portillo, Erin, Clark, Terry S, Judd, Scott, Feinberg, C. Kirk, Benitez, Marie, Runyan, Candace, Hackett, Lindsey, Lafey, Scott, Richardson, Danielle, Vineyard, Sarah, Tefend Campbell, Mary, Dharajiya, Nilesh, Jensen, Taylor J, van den Boom, Dirk, Diaz, Luis A, Grosu, Daniel S, Polk, Arthur, Marsal, Kalle, Hicks, Susan Cho, Lytle, Katherine M, Holtvoigt, Lauren, Chibuk, Jason, Chorny, Ilya, Tsui, Dana W. Y

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Abstract 633: Application of a novel analytical metric that quantifies copy number alterations in low-coverage, genome-wide sequencing of cell-free DNA to monitor and differentiate... von Jensen, Taylor J., Goodman, Aaron M., Ellison, Christopher K., Kato, Shumei, Daniels, Gregory A., Tran, Lisa, Nakashe, Prachi, McCarthy, Erin, Mazloom, Amin R., McLennan, Graham, Grosu, Daniel S., Ehrich, Mathias, Kurzrock, Razelle

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Low-coverage, genome-wide sequencing of cell-free DNA developed for noninvasive prenatal testing (NIPT) to enable genomic characterization that can be used to monitor immunotherapy... von Jensen, Taylor J., Goodman, Aaron, Kato, Shumei, Ellison, Christopher K, Daniels, Gregory A., Tran, Lisa, McCarthy, Erin, Nakashe, Prachi, Mazloom, Amin, McLennan, Graham, Grosu, Daniel S., Ehrich, Mathias, Kurzrock, Razelle

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Abstract 5693: Low coverage genome-wide sequencing of cell-free DNA enables detection, therapeutic monitoring, and characterization of copy number alterations in patients with soli... von Ellison, Christopher K., Goodman, Aaron M., Riethdorf, Sabine, Mazloom, Amin R., Tran, Lisa, Nakashe, Prachi, McCarthy, Erin, Gorges, Tobias, Stein, Alexander, Quidde, Julia, Grosu, Daniel S., Ehrich, Mathias, Jensen, Taylor J., Pantel, Klaus, Kurzrock, Razelle

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Abstract 1612: Comparative oncology analysis of canine cancer by tumor and liquid biopsy testing for biomarker and therapeutic discovery in humans and dogs von Chorny, Ilya, Kruglyak, Kristina M., Tynan, John A., Hernandez, Gilberto E., Nakashe, Prachi, Hicks, Susan, Motalli-Pepio, Rita, McLennan, Lisa, Holtvoigt, Lauren E., Rafalko, Jill M., Chibuk, Jason, McCleary-Wheeler, Angela L., Flory, Andi, Grosu, Daniel S., Tsui, Dana W.

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Abstract A16: Liquid biopsy for the detection and characterization of canine lymphoma von McCleary-Wheeler, Angela L, Kruglyak, Kristina M, Hernandez, Gilberto E, Nakashe, Prachi, McLennan, Lisa M, Jennings, Thuy, Rafalko, Jill M, Holtvoigt, Lauren E, Grosu, Daniel S, Chibuk, Jason, Hicks, Susan C, Tynan, John A, Chorny, Ilya, Tsui, Dana WY, Flory, Andi

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Structure Function Studies of the Proton Coupled Folate Transporter von Nakashe, Prachi, Duddempudi, Phaneendra K., Blanton, Michael P., Jansen, Michaela

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Clinical validation of a next-generation sequencing-based multi-cancer early detection "liquid biopsy" blood test in over 1,000 dogs using an independent testing set: The CANcer De... von Andi Flory, Kristina M Kruglyak, John A Tynan, Lisa M McLennan, Jill M Rafalko, Patrick Christian Fiaux, Gilberto E Hernandez, Francesco Marass, Prachi Nakashe, Carlos A Ruiz-Perez, Donna M Fath, Thuy Jennings, Rita Motalli-Pepio, Kate Wotrang, Angela L McCleary-Wheeler, Susan Lana, Brenda Phillips, Brian K Flesner, Nicole F Leibman, Tracy LaDue, Chelsea D Tripp, Brenda L Coomber, J Paul Woods, Mairin Miller, Sean W Aiken, Amber Wolf-Ringwall, Antonella Borgatti, Kathleen Kraska, Christopher B Thomson, Alane Kosanovich Cahalane, Rebecca L Murray, William C Kisseberth, Maria A Camps-Palau, Franck Floch, Claire Beaudu-Lange, Aurélia Klajer-Peres, Olivier Keravel, Luc-André Fribourg-Blanc, Pascale Chicha Mazetier, Angelo Marco, Molly B McLeod, Erin Portillo, Terry S Clark, Scott Judd, C Kirk Feinberg, Marie Benitez, Candace Runyan, Lindsey Hackett, Scott Lafey, Danielle Richardson, Sarah Vineyard, Mary Tefend Campbell, Nilesh Dharajiya, Taylor J Jensen, Dirk van den Boom, Luis A Diaz, Daniel S Grosu, Arthur Polk, Kalle Marsal, Susan Cho Hicks, Katherine M Lytle, Lauren Holtvoigt, Jason Chibuk, Ilya Chorny, Dana W Y Tsui

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