Insights into the ISG15 transfer cascade by the UBE1L activating enzyme von Wallace, Iona, Baek, Kheewoong, Prabu, J. Rajan, Vollrath, Ronnald, von Gronau, Susanne, Schulman, Brenda A., Swatek, Kirby N.

Volltext

Interaction of Circadian Clock Proteins CRY1 and PER2 Is Modulated by Zinc Binding and Disulfide Bond Formation von Schmalen, Ira, Reischl, Silke, Wallach, Thomas, Klemz, Roman, Grudziecki, Astrid, Prabu, J. Rajan, Benda, Christian, Kramer, Achim, Wolf, Eva

Volltext

CUL5-ARIH2 E3-E3 ubiquitin ligase structure reveals cullin-specific NEDD8 activation von Kostrhon, Sebastian, Prabu, J. Rajan, Baek, Kheewoong, Horn-Ghetko, Daniel, von Gronau, Susanne, Klügel, Maren, Basquin, Jérôme, Alpi, Arno F., Schulman, Brenda A.

Volltext

Structure of the RNA Helicase MLE Reveals the Molecular Mechanisms for Uridine Specificity and RNA-ATP Coupling von Prabu, J. Rajan, Müller, Marisa, Thomae, Andreas W., Schüssler, Steffen, Bonneau, Fabien, Becker, Peter B., Conti, Elena

Volltext

Interconversion between Anticipatory and Active GID E3 Ubiquitin Ligase Conformations via Metabolically Driven Substrate Receptor Assembly von Qiao, Shuai, Langlois, Christine R., Chrustowicz, Jakub, Sherpa, Dawafuti, Karayel, Ozge, Hansen, Fynn M., Beier, Viola, von Gronau, Susanne, Bollschweiler, Daniel, Schäfer, Tillman, Alpi, Arno F., Mann, Matthias, Prabu, J. Rajan, Schulman, Brenda A.

Volltext

Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex von Schuller, Sandra K, Schuller, Jan M, Prabu, J Rajan, Baumgärtner, Marc, Bonneau, Fabien, Basquin, Jérôme, Conti, Elena

Volltext

Snapshots of RecA Protein Involving Movement of the C-domain and Different Conformations of the DNA-binding Loops: Crystallographic and Comparative Analysis of 11 Structures of Myc... von Krishna, R., Prabu, J. Rajan, Manjunath, G.P., Datta, S., Chandra, N.R., Muniyappa, K., Vijayan, M.

Volltext

Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site von Watson, Edmond R., Grace, Christy R. R., Zhang, Wei, Miller, Darcie J., Davidson, Iain F., Prabu, J. Rajan, Yu, Shanshan, Bolhuis, Derek L., Kulko, Elizaveta T., Vollrath, Ronnald, Haselbach, David, Stark, Holger, Peters, Jan-Michael, Brown, Nicholas G., Sidhu, Sachdev S., Schulman, Brenda A.

Volltext

NEDD8 nucleates a multivalent cullin–RING–UBE2D ubiquitin ligation assembly von Baek, Kheewoong, Krist, David T., Prabu, J. Rajan, Hill, Spencer, Klügel, Maren, Neumaier, Lisa-Marie, von Gronau, Susanne, Kleiger, Gary, Schulman, Brenda A.

Volltext

Ubiquitin ligation to F-box protein targets by SCF–RBR E3–E3 super-assembly von Horn-Ghetko, Daniel, Krist, David T., Prabu, J. Rajan, Baek, Kheewoong, Mulder, Monique P. C., Klügel, Maren, Scott, Daniel C., Ovaa, Huib, Kleiger, Gary, Schulman, Brenda A.

Volltext

Gene expression and cell identity controlled by anaphase-promoting complex von Oh, Eugene, Mark, Kevin G., Mocciaro, Annamaria, Watson, Edmond R., Prabu, J. Rajan, Cha, Denny D., Kampmann, Martin, Gamarra, Nathan, Zhou, Coral Y., Rape, Michael

Volltext

Mechanism of millisecond Lys48-linked poly-ubiquitin chain formation by cullin-RING ligases von Liwocha, Joanna, Li, Jerry, Purser, Nicholas, Rattanasopa, Chutima, Maiwald, Samuel, Krist, David T., Scott, Daniel C., Steigenberger, Barbara, Prabu, J. Rajan, Schulman, Brenda A., Kleiger, Gary

Volltext

GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme von Sherpa, Dawafuti, Chrustowicz, Jakub, Qiao, Shuai, Langlois, Christine R., Hehl, Laura A., Gottemukkala, Karthik Varma, Hansen, Fynn M., Karayel, Ozge, von Gronau, Susanne, Prabu, J. Rajan, Mann, Matthias, Alpi, Arno F., Schulman, Brenda A.

Volltext

Multifaceted N-Degron Recognition and Ubiquitylation by GID/CTLH E3 Ligases von Chrustowicz, Jakub, Sherpa, Dawafuti, Teyra, Joan, Loke, Mun Siong, Popowicz, Grzegorz M., Basquin, Jerome, Sattler, Michael, Prabu, J. Rajan, Sidhu, Sachdev S., Schulman, Brenda A.

Volltext

Structural snapshots along K48-linked ubiquitin chain formation by the HECT E3 UBR5 von Hehl, Laura A., Horn-Ghetko, Daniel, Prabu, J. Rajan, Vollrath, Ronnald, Vu, D. Tung, Pérez Berrocal, David A., Mulder, Monique P. C., van der Heden van Noort, Gerbrand J., Schulman, Brenda A.

Volltext

Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting von Li, Jerry, Purser, Nicholas, Liwocha, Joanna, Scott, Daniel C., Byers, Holly A., Steigenberger, Barbara, Hill, Spencer, Tripathi-Giesgen, Ishita, Hinkle, Trent, Hansen, Fynn M., Prabu, J. Rajan, Radhakrishnan, Senthil K., Kirkpatrick, Donald S., Reichermeier, Kurt M., Schulman, Brenda A., Kleiger, Gary

Volltext

Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies von Chrustowicz, Jakub, Sherpa, Dawafuti, Li, Jerry, Langlois, Christine R., Papadopoulou, Eleftheria C., Vu, D. Tung, Hehl, Laura A., Karayel, Özge, Beier, Viola, von Gronau, Susanne, Müller, Judith, Prabu, J. Rajan, Mann, Matthias, Kleiger, Gary, Alpi, Arno F., Schulman, Brenda A.

Volltext

Noncanonical assembly, neddylation and chimeric cullin–RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex von Horn-Ghetko, Daniel, Hopf, Linus V. M., Tripathi-Giesgen, Ishita, Du, Jiale, Kostrhon, Sebastian, Vu, D. Tung, Beier, Viola, Steigenberger, Barbara, Prabu, J. Rajan, Stier, Luca, Bruss, Elias M., Mann, Matthias, Xiong, Yue, Schulman, Brenda A.

Volltext

Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability von Chandran, Anu V, Prabu, J Rajan, Nautiyal, Astha, Patil, K Neelakanteshwar, Muniyappa, K, Vijayan, M

Volltext

Crystallographic and modelling studies on Mycobacterium tuberculosis RuvA: Additional role of RuvB- binding domain and inter species variability von Prabu, JRajan, Thamotharan, S, Khanduja, Jasbeer Singh, Chandra, Nagasuma R, Muniyappa, K, Vijayan, M

Volltext