Safety and pharmacodynamics of intranasal GSK2245035, a TLR7 agonist for allergic rhinitis: A randomized trial von Ellis, A. K., Tsitoura, D. C., Quint, D., Powley, W., Lee, L. A.

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Early clinical evaluation of the intranasal TLR7 agonist GSK2245035: Use of translational biomarkers to guide dosing and confirm target engagement von Tsitoura, D, Ambery, C, Price, M, Powley, W, Garthside, S, Biggadike, K, Quint, D

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(Q)SAR assessments of potentially mutagenic impurities: A regulatory perspective on the utility of expert knowledge and data submission von Powley, Mark W.

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Specificity of human anti‐variable heavy (VH) chain autoantibodies and impact on the design and clinical testing of a VH domain antibody antagonist of tumour necrosis factor‐α rece... von Cordy, J. C., Morley, P. J., Wright, T. J., Birchler, M. A., Lewis, A. P., Emmins, R., Chen, Y. Z., Powley, W. M., Bareille, P. J., Wilson, R., Tonkyn, J., Bayliffe, A. I., Lazaar, A. L.

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N-nitrosamine impurity risk assessment in pharmaceuticals: Utilizing In vivo mutation relative potency comparison to establish an acceptable intake for NTTP von Powley, Mark W., Sobol, Zhanna, Johnson, George E., Clark, Robert W., Dalby, Stephen M., Ykoruk, Bridget A., Galijatovic-Idrizbegovic, Alema, Mowery, Mark D., Escobar, Patricia A.

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Calculating qualified non-mutagenic impurity levels: Harmonization of approaches von Graham, Jessica C., Powley, Mark W., Udovic, Erika, Glowienke, Susanne, Nicolette, John, Parris, Patricia, Kenyon, Michelle, White, Angela, Maisey, Ailis, Harvey, James, Martin, Elizabeth A., Dowdy, Eric, Masuda-Herrera, Melisa, Trejo-Martin, Alejandra, Bercu, Joel

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Quantification of DNA and hemoglobin adducts of 3,4-epoxy-1,2-butanediol in rodents exposed to 3-butene-1,2-diol von Powley, M.W., Li, Y., Upton, P.B., Walker, V.E., Swenberg, J.A.

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S142 Investigating patterns in 24 hours of coughing von Dockry, R J, Sunger, K, Marsden, P, Kelsall, A, Decalmer, S, Powley, W, Murdoch, R, Woodcock, A, Smith, J A

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Hepatic and pulmonary microsomal benzene metabolism in CYP2E1 knockout mice von Powley, Mark W, Carlson, Gary P

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Species comparison of hepatic and pulmonary metabolism of benzene von Powley, Mark W, Carlson, Gary P

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The importance of 3,4-epoxy-1,2-butanediol and hydroxymethylvinyl ketone in 3-butene-1,2-diol associated mutagenicity von Powley, Mark W., Walker, Vernon E., Li, Yutai, Upton, Patricia B., Swenberg, James A.

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Safety Assessment of Drug Metabolites: Implications of Regulatory Guidance and Potential Application of Genetically Engineered Mouse Models that Express Human P450s von Powley, Mark W, Frederick, Clay B, Sistare, Frank D, DeGeorge, Joseph J

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Quantile-Parameterized Distributions von Keelin, Thomas W, Powley, Bradford W

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Safety and pharmacodynamics of intranasal GSK 2245035, a TLR 7 agonist for allergic rhinitis: A randomized trial von Ellis, A. K., Tsitoura, D. C., Quint, D., Powley, W., Lee, L. A.

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Timing of Carcinogenicity Studies and Predictability of Genotoxicity for Tumorigenicity in Anti-HIV Drug Development von Wu, Kuei-Meng, Powley, Mark W., Ghantous, Hanan

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1,N 2-Propanodeoxyguanosine Adducts of the 1,3-Butadiene Metabolite, Hydroxymethylvinyl Ketone von Powley, Mark W, Jayaraj, Karupiah, Gold, Avram, Ball, Louise M, Swenberg, James A

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BENZENE METABOLISM BY THE ISOLATED PERFUSED LUNG von Powley, Mark W., Carlson, Gary P.

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Cytochromes P450 involved with benzene metabolism in hepatic and pulmonary microsomes von Powley, Mark W., Carlson, Gary P.

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Cytochrome P450 isozymes involved in the metabolism of phenol, a benzene metabolite von Powley, Mark W, Carlson, Gary P

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Specificity of human anti-variable heavy (VH) chain autoantibodies and impact on the design and clinical testing of a VH domain antibody antagonist of tumour necrosis factor-[alpha... von Cordy, J C, Morley, P J, Wright, T J, Birchler, M A, Lewis, A P, Emmins, R, Chen, Y Z, Powley, W M, Bareille, P J, Wilson, R, Tonkyn, J, Bayliffe, A I, Lazaar, A L

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