Manipulation of mRNA translation elongation influences the fragmentation of a biotherapeutic Fc‐fusion protein produced in CHO cells von Knight, Tanya J., Povey, Jane F., Vito, Davide, Mohindra, Atul, Jaques, Colin M., Smales, C. Mark

Volltext

The effect of formulation variables on protein stability and integrity of a model IgG4 monoclonal antibody and translation to formulation of a model ScFv von Gourbatsi, Evdoxia, Povey, Jane F., Smales, C. Mark

Volltext

Comparison of the effects of 2,2,2-trifluoroethanol on peptide and protein structure and function von Povey, Jane F., Smales, C. Mark, Hassard, Stuart J., Howard, Mark J.

Volltext

Rapid high-throughput characterisation, classification and selection of recombinant mammalian cell line phenotypes using intact cell MALDI-ToF mass spectrometry fingerprinting and... von Povey, Jane F., O’Malley, Christopher J., Root, Tracy, Martin, Elaine B., Montague, Gary A., Feary, Marc, Trim, Carol, Lang, Dietmar A., Alldread, Richard, Racher, Andrew J., Smales, C. Mark

Volltext

H NMR spectroscopy profiling of metabolic reprogramming of Chinese hamster ovary cells upon a temperature shift during culture von Wagstaff, Jane L, Masterton, Rosalyn J, Povey, Jane F, Smales, C Mark, Howard, Mark J

Volltext

1H NMR Spectroscopy Profiling of Metabolic Reprogramming of Chinese Hamster Ovary Cells upon a Temperature Shift during Culture von Wagstaff, Jane L., Masterton, Rosalyn J., Povey, Jane F., Smales, C. Mark, Howard, Mark J.

Volltext

A proline metabolism selection system and its application to the engineering of lipid biosynthesis in Chinese hamster ovary cells von Budge, James D., Roobol, Joanne, Singh, Gurdeep, Mozzanino, Théo, Knight, Tanya J., Povey, Jane, Dean, Andrew, Turner, Sarah J., Jaques, Colin M., Young, Robert J., Racher, Andrew J., Smales, C. Mark

Volltext

Intact-Cell MALDI-ToF Mass Spectrometry for the Authentication of Drug-Adapted Cancer Cell Lines von Povey, Jane F, Saintas, Emily, Aderemi, Adewale V, Rothweiler, Florian, Zehner, Richard, Dirks, Wilhelm G, Cinatl, Jr, Jindrich, Racher, Andrew J, Wass, Mark N, Smales, C Mark, Michaelis, Martin

Volltext

MALDI-ToF mass spectrometry coupled with multivariate pattern recognition analysis for the rapid biomarker profiling of Escherichia coli in different growth phases von Momo, Remi A., Povey, Jane F., Smales, C. Mark, O’Malley, Christopher J., Montague, Gary A., Martin, Elaine B.

Volltext

Data for engineering lipid metabolism of Chinese hamster ovary (CHO) cells for enhanced recombinant protein production von Budge, James D., Knight, Tanya J., Povey, Jane, Roobol, Joanne, Brown, Ian R., Singh, Gurdeep, Dean, Andrew, Turner, Sarah, Jaques, Colin M., Young, Robert J., Racher, Andrew J., Smales, C Mark

Volltext

The effect of peptide glycation on local secondary structure von Povey, Jane F., Howard, Mark J., Williamson, Richard A., Smales, C. Mark

Volltext

Investigating variables and mechanisms that influence protein integrity in low water content amorphous carbohydrate matrices von Povey, Jane F., Perez-Moral, Natalia, Noel, Timothy R., Parker, Roger, Howard, Mark J., Smales, C. Mark

Volltext

A cell culture platform for Cryptosporidium that enables long-term cultivation and new tools for the systematic investigation of its biology von Miller, Christopher N., Jossé, Lyne, Brown, Ian, Blakeman, Ben, Povey, Jane, Yiangou, Lyto, Price, Mark, Cinatl, Jindrich, Xue, Wei-Feng, Michaelis, Martin, Tsaousis, Anastasios D.

Volltext

Engineering of Chinese hamster ovary cell lipid metabolism results in an expanded ER and enhanced recombinant biotherapeutic protein production von Budge, James D., Knight, Tanya J., Povey, Jane, Roobol, Joanne, Brown, Ian R., Singh, Gurdeep, Dean, Andrew, Turner, Sarah, Jaques, Colin M., Young, Robert J., Racher, Andrew J., Smales, C. Mark

Volltext

Biotherapeutic protein formulation variables influence protein integrity and can promote post-translational modifications as shown using chicken egg white lysozyme as a model syste... von Gourbatsi, Evdoxia, Povey, Jane, Uddin, Shahid, Smales, C. Mark

Volltext

Raw data to accompany the manuscript 'Data for Engineering Lipid Metabolism of Chinese Hamster Ovary (CHO) Cells for Enhanced Recombinant Protein Production' published in the Journ... von Budge, James D, Knight, Tanya J, Povey, Jane, Roobol, Joanne, Brown, Ian R, Singh, Gurdeep, Dean, Andrew, Turner, Sarah, Jaques, Colin M, Young, Robert J, Racher, Andrew J, Smales, C Mark

Volltext bestellen

Rapid method for targeted cell (line) selection von Root, Tracy S, O'Malley, Christopher J, Trim, Carol M, Racher, Andrew J, Smales, Christopher M, Montague, Gary A, Lang, Dietmar, Povey, Jane F, Martin, Elaine B

Volltext bestellen

Rapid Method For Targeted Cell (Line) Selection von POVEY Jane F, LANG Dietmar, MARTIN Elaine B, ROOT Tracy S, O'MALLEY Christopher J, TRIM Carol M, MONTAGUE Gary A, RACHER Andrew J, SMALES Christopher M

Volltext bestellen

Polypeptide—metal cluster connectivities in Cd(II) GAL4 von Gadhavi, Paresh L., Davis, Adrian L., Povey, Jane F., Keeler, James, Laue, Ernest D.

Volltext

Metal ion co-ordination in the DNA binding domain of the yeast transcriptional activator GAL4 von Povey, Jane F., Diakun, Gregory P., Garner, C.David, Wilson, Stephen P., Laue, Ernest D.

Volltext