Integrin inactivators: balancing cellular functions in vitro and in vivo von Bouvard, Daniel, Pouwels, Jeroen, De Franceschi, Nicola, Ivaska, Johanna

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Assessment of the WAP-Myc mouse mammary tumor model for spontaneous metastasis von Utz, Begüm, Turpin, Rita, Lampe, Johanna, Pouwels, Jeroen, Klefström, Juha

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The Sharpin interactome reveals a role for Sharpin in lamellipodium formation via the Arp2/3 complex von Khan, Meraj H, Salomaa, Siiri I, Jacquemet, Guillaume, Butt, Umar, Miihkinen, Mitro, Deguchi, Takahiro, Kremneva, Elena, Lappalainen, Pekka, Humphries, Martin J, Pouwels, Jeroen

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Compressive stress-mediated p38 activation required for ERα + phenotype in breast cancer von Munne, Pauliina M., Martikainen, Lahja, Räty, Iiris, Bertula, Kia, Nonappa, Ruuska, Janika, Ala-Hongisto, Hanna, Peura, Aino, Hollmann, Babette, Euro, Lilya, Yavuz, Kerim, Patrikainen, Linda, Salmela, Maria, Pokki, Juho, Kivento, Mikko, Väänänen, Juho, Suomi, Tomi, Nevalaita, Liina, Mutka, Minna, Kovanen, Panu, Leidenius, Marjut, Meretoja, Tuomo, Hukkinen, Katja, Monni, Outi, Pouwels, Jeroen, Sahu, Biswajyoti, Mattson, Johanna, Joensuu, Heikki, Heikkilä, Päivi, Elo, Laura L., Metcalfe, Ciara, Junttila, Melissa R., Ikkala, Olli, Klefström, Juha

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Hepsin promotes breast tumor growth signaling via the TGFβ‐EGFR axis von Belitškin, Denis, Munne, Pauliina, Pant, Shishir M., Anttila, Johanna M., Suleymanova, Ilida, Belitškina, Kati, Kirchhofer, Daniel, Janetka, James, Käsper, Taivo, Jalil, Sami, Pouwels, Jeroen, Tervonen, Topi A., Klefström, Juha

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Mutually Exclusive Roles of SHARPIN in Integrin Inactivation and NF-κB Signaling von De Franceschi, Nicola, Peuhu, Emilia, Parsons, Maddy, Rissanen, Sami, Vattulainen, Ilpo, Salmi, Marko, Ivaska, Johanna, Pouwels, Jeroen

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Integrin beta 1 inhibition alleviates the chronic hyperproliferative dermatitis phenotype of SHARPIN-deficient mice von Peuhu, Emilia, Salomaa, Siiri I, De Franceschi, Nicola, Potter, Christopher S, Sundberg, John P, Pouwels, Jeroen

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Negative regulators of integrin activity von Pouwels, Jeroen, Nevo, Jonna, Pellinen, Teijo, Ylänne, Jari, Ivaska, Johanna

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SHARPIN Regulates Uropod Detachment in Migrating Lymphocytes von Pouwels, Jeroen, De Franceschi, Nicola, Rantakari, Pia, Auvinen, Kaisa, Karikoski, Marika, Mattila, Elina, Potter, Christopher, Sundberg, John P., Hogg, Nancy, Gahmberg, Carl G., Salmi, Marko, Ivaska, Johanna

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Respiratory complex I regulates dendritic cell maturation in explant model of human tumor immune microenvironment von Turpin, Rita, Liu, Ruixian, Munne, Pauliina M, Peura, Aino, Rannikko, Jenna H, Philips, Gino, Boeckx, Bram, Salmelin, Natasha, Hurskainen, Elina, Suleymanova, Ilida, Aung, July, Vuorinen, Elisa M, Lehtinen, Laura, Mutka, Minna, Kovanen, Panu E, Niinikoski, Laura, Meretoja, Tuomo J, Mattson, Johanna, Mustjoki, Satu, Saavalainen, Päivi, Goga, Andrei, Lambrechts, Diether, Pouwels, Jeroen, Hollmén, Maija, Klefström, Juha

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A ZO-1/α5β1-integrin complex regulates cytokinesis downstream of PKCε in NCI-H460 cells plated on fibronectin von Hämälistö, Saara, Pouwels, Jeroen, de Franceschi, Nicola, Saari, Markku, Ivarsson, Ylva, Zimmermann, Pascale, Brech, Andreas, Stenmark, Harald, Ivaska, Johanna

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Shugoshin 1 Plays a Central Role in Kinetochore Assembly and is Required for Kinetochore Targeting of Plk1 von Pouwels, Jeroen, Kukkonen, Anu M., Lan, Weijie, Daum, John R., Gorbsky, Gary J., Stukenberg, P. Todd, Kallio, Marko J.

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SHARPIN S146 phosphorylation mediates ARP2/3 interaction, cancer cell invasion and metastasis von Butt, Umar, Khan, Meraj H., Pouwels, Jeroen, Westermarck, Jukka

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SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras von Lilja, Johanna, Zacharchenko, Thomas, Georgiadou, Maria, Jacquemet, Guillaume, Franceschi, Nicola De, Peuhu, Emilia, Hamidi, Hellyeh, Pouwels, Jeroen, Martens, Victoria, Nia, Fatemeh Hassani, Beifuss, Malte, Boeckers, Tobias, Kreienkamp, Hans-Juergen, Barsukov, Igor L., Ivaska, Johanna

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Abstract 1115: Patient-derived explant cultures (PDECs) as a model system for immuno-oncology studies von Turpin, Rita, Munne, Pauliina, Suleymanova, Ilida, Mustjoki, Satu, Pouwels, Jeroen, Klefström, Juha

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Correction: The Sharpin interactome reveals a role for Sharpin in lamellipodium formation via the Arp2/3 complex von Khan, Meraj H., Salomaa, Siiri I., Jacquemet, Guillaume, Butt, Umar, Miihkinen, Mitro, Deguchi, Takahiro, Kremneva, Elena, Lappalainen, Pekka, Humphries, Martin J., Pouwels, Jeroen

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Selective integrin endocytosis is driven by interactions between the integrin α-chain and AP2 von De Franceschi, Nicola, Arjonen, Antti, Elkhatib, Nadia, Denessiouk, Konstantin, Wrobel, Antoni G, Wilson, Thomas A, Pouwels, Jeroen, Montagnac, Guillaume, Owen, David J, Ivaska, Johanna

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SHARPIN is an endogenous inhibitor of β1-integrin activation von Ivaska, Johanna, Rantala, Juha K, Pouwels, Jeroen, Pellinen, Teijo, Veltel, Stefan, Laasola, Petra, Mattila, Elina, Potter, Christopher S, Duffy, Ted, Sundberg, John P, Kallioniemi, Olli, Askari, Janet A, Humphries, Martin J, Parsons, Maddy, Salmi, Marko

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Hepsin regulates TGFβ signaling via fibronectin proteolysis von Belitškin, Denis, Pant, Shishir M, Munne, Pauliina, Suleymanova, Ilida, Belitškina, Kati, Hongisto, Hanna-Ala, Englund, Johanna, Raatikainen, Tiina, Klezovitch, Olga, Vasioukhin, Valeri, Li, Shuo, Wu, Qingyu, Monni, Outi, Kuure, Satu, Laakkonen, Pirjo, Pouwels, Jeroen, Tervonen, Topi A, Klefström, Juha

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Hepsin regulates TGFβ signaling via fibronectin proteolysis von Belitskin, Denis, Pant, Shishir, Munne, Pauliina, Suleymanova, Ilida, Belitškina, Kati, Hongisto, Hanna‐Ala, Englund, Johanna, Raatikainen, Tiina, Vasioukhin, Valeri, Klezovitch, Olga, Li, Shuo, Wu, Qingyu, Monni, Outi, Kuure, Satu, Laakonen, Pirjo, Pouwels, Jeroen, Tervonen, Topi, Klefström, Juha

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