Unraveling the mechanisms of intrinsic drug resistance in Mycobacterium tuberculosis von Poulton, Nicholas C, Rock, Jeremy M

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CRISPRi chemical genetics and comparative genomics identify genes mediating drug potency in Mycobacterium tuberculosis von Li, Shuqi, Poulton, Nicholas C., Chang, Jesseon S., Azadian, Zachary A., DeJesus, Michael A., Ruecker, Nadine, Zimmerman, Matthew D., Eckartt, Kathryn A., Bosch, Barbara, Engelhart, Curtis A., Sullivan, Daniel F., Gengenbacher, Martin, Dartois, Véronique A., Schnappinger, Dirk, Rock, Jeremy M.

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Cyclic AMP is a critical mediator of intrinsic drug resistance and fatty acid metabolism in M. tuberculosis von Wong, Andrew I, Beites, Tiago, Planck, Kyle A, Fieweger, Rachael A, Eckartt, Kathryn A, Li, Shuqi, Poulton, Nicholas C, VanderVen, Brian C, Rhee, Kyu Y, Schnappinger, Dirk, Ehrt, Sabine, Rock, Jeremy

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Genome-wide gene expression tuning reveals diverse vulnerabilities of M. tuberculosis von Bosch, Barbara, DeJesus, Michael A., Poulton, Nicholas C., Zhang, Wenzhu, Engelhart, Curtis A., Zaveri, Anisha, Lavalette, Sophie, Ruecker, Nadine, Trujillo, Carolina, Wallach, Joshua B., Li, Shuqi, Ehrt, Sabine, Chait, Brian T., Schnappinger, Dirk, Rock, Jeremy M.

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Mutations in rv0678 Confer Low-Level Resistance to Benzothiazinone DprE1 Inhibitors in Mycobacterium tuberculosis von Poulton, Nicholas C, Azadian, Zachary A, DeJesus, Michael A, Rock, Jeremy M

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Beyond antibiotic resistance: The whiB7 transcription factor coordinates an adaptive response to alanine starvation in mycobacteria von Poulton, Nicholas C., DeJesus, Michael A., Munsamy-Govender, Vanisha, Kanai, Mariko, Roberts, Cameron G., Azadian, Zachary A., Bosch, Barbara, Lin, Karl Matthew, Li, Shuqi, Rock, Jeremy M.

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Compensatory evolution in NusG improves fitness of drug-resistant M. tuberculosis von Eckartt, Kathryn A., Delbeau, Madeleine, Munsamy-Govender, Vanisha, DeJesus, Michael A., Azadian, Zachary A., Reddy, Abhijna K., Chandanani, Joshua, Poulton, Nicholas C., Quiñones-Garcia, Stefany, Bosch, Barbara, Landick, Robert, Campbell, Elizabeth A., Rock, Jeremy M.

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The essential M. tuberculosis Clp protease is functionally asymmetric in vivo von d'Andrea, Felipe B, Poulton, Nicholas C, Froom, Ruby, Tam, Kayan, Campbell, Elizabeth A, Rock, Jeremy M

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ChAd63-MVA–vectored Blood-stage Malaria Vaccines Targeting MSP1 and AMA1: Assessment of Efficacy Against Mosquito Bite Challenge in Humans von Sheehy, Susanne H, Duncan, Christopher JA, Elias, Sean C, Choudhary, Prateek, Biswas, Sumi, Halstead, Fenella D, Collins, Katharine A, Edwards, Nick J, Douglas, Alexander D, Anagnostou, Nicholas A, Ewer, Katie J, Havelock, Tom, Mahungu, Tabitha, Bliss, Carly M, Miura, Kazutoyo, Poulton, Ian D, Lillie, Patrick J, Antrobus, Richard D, Berrie, Eleanor, Moyle, Sarah, Gantlett, Katherine, Colloca, Stefano, Cortese, Riccardo, Long, Carole A, Sinden, Robert E, Gilbert, Sarah C, Lawrie, Alison M, Doherty, Tom, Faust, Saul N, Nicosia, Alfredo, Hill, Adrian VS, Draper, Simon J

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Evaluation of the Efficacy of ChAd63-MVA Vectored Vaccines Expressing Circumsporozoite Protein and ME-TRAP Against Controlled Human Malaria Infection in Malaria-Naive Individuals von Hodgson, Susanne H., Ewer, Katie J., Bliss, Carly M., Edwards, Nick J., Rampling, Thomas, Anagnostou, Nicholas A., de Barra, Eoghan, Havelock, Tom, Bowyer, Georgina, Poulton, Ian D., de Cassan, Simone, Longley, Rhea, Illingworth, Joseph J., Douglas, Alexander D., Mange, Pooja B., Collins, Katharine A., Roberts, Rachel, Gerry, Stephen, Berrie, Eleanor, Moyle, Sarah, Colloca, Stefano, Cortese, Riccardo, Sinden, Robert E., Gilbert, Sarah C., Bejon, Philip, Lawrie, Alison M., Nicosia, Alfredo, Faust, Saul N., Hill, Adrian V. S.

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The 2008 Emiliania huxleyi bloom along the Patagonian Shelf: Ecology, biogeochemistry, and cellular calcification von Poulton, Alex J., Painter, Stuart C., Young, Jeremy R., Bates, Nicholas R., Bowler, Bruce, Drapeau, Dave, Lyczsckowski, Emily, Balch, William M.

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Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disea... von Arora, Megha, Brown, Alexandria, Casey, Daniel C, Chen, Alan Z, Coggeshall, Megan, Dilegge, Tina, Smith, Alison, Steiner, Caitlyn, Abraham, Biju, Abubakar, Ibrahim, Abu-Raddad, Laith J, Agardh, Emilie Elisabet, Ajala, Oluremi N, Al-Aly, Ziyad, Alam, Khurshid, Assadi, Reza, Atique, Suleman, Awasthi, Ashish, Bazargan-Hejazi, Shahrzad, Bell, Michelle L, Beyene, Addisu Shunu, Bisanzio, Donal, Blore, Jed, Borschmann, Rohan, Campuzano, Julio Cesar, Chibueze, Chioma Ezinne, Dargan, Paul I, Derrett, Sarah, Dharmaratne, Samath D, Diaz-Torné, Cesar, Duan, Leilei, Duncan, Bruce Bartholow, Ellenbogen, Richard G, Fereshtehnejad, Seyed-Mohammad, Fernandes, Jefferson G, Fischer, Florian, Fitchett, Joseph R A, Frostad, Joseph, Futran, Neal D, Gebre, Teshome, Gibney, Katherine B, Goodridge, Amador, Hailu, Alemayehu Desalegne, Handal, Alexis J, Harb, Hilda L, Harikrishnan, Sivadasanpillai, Hay, Roderick J, Horino, Masako, Huang, Hsiang, Jiang, Ying, Karema, Corine Kakizi, Kasaeian, Amir, Keiyoro, Peter Njenga, Koul, Parvaiz A, Lalloo, Ratilal, Leasher, Janet L, Leigh, James, Lo, Warren D, Lunevicius, Raimundas, Lyons, Ronan A, Memish, Ziad A, Mitchell, Philip B, Mohammed, Shafiu, Montico, Marcella, Morawska, Lidia, Mumford, John Everett, Nagel, Gabriele, Nguyen, Quyen Le, Norheim, Ole F, Oh, In-Hwan, Olusanya, Bolajoko Olubukunola, Piel, Frédéric B, Rabiee, Rynaz H S, Radfar, Amir, Rahman, Sajjad Ur, Reitsma, Marissa B, Remuzzi, Giuseppe, Roy, Ambuj, Santos, Itamar S, Satpathy, Maheswar, Savic, Miloje, Schöttker, Ben, Seedat, Soraya, Sepanlou, Sadaf G, Servan-Mori, Edson E, Sharma, Upasana, Shiue, Ivy, Singh, Om Prakash, Singh, Prashant Kumar, Skogen, Jens Christoffer, Sorensen, Reed J D, Sunguya, Bruno F, Szoeke, Cassandra E I, Truelsen, Thomas, Ukwaja, Kingsley N, Verma, Raj Kumar, Vlassov, Vasiliy Victorovich, Williams, Hywel C, Woodbrook, Rachel, Yip, Paul

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Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of... von Casey, Daniel C, Fitzmaurice, Christina, Gething, Peter W, Huynh, Chantal, Kinfu, Yohannes, Kyu, Hmwe H, Pigott, David M, Sandar, Logan, VanderZanden, Amelia, Abbafati, Cristiana, Abbas, Kaja M, Abu-Raddad, Laith J, Abyu, Gebre Yitayih, Achoki, Tom, Adou, Arsène Kouablan, Agarwal, Arnav, Akseer, Nadia, Aldridge, Robert William, Ali, Raghib, Martin, Elena Alvarez, Anderson, Gregory M, Awasthi, Ashish, Bikbov, Boris, Biryukov, Stan, Brewer, Jerry D, Buckle, Geoffrey Colin, Carpenter, David O, Damsere-Derry, James, de Jager, Pieter, Deribew, Amare, dos Santos, Kadine Priscila Bender, Dossou, Edem, Duncan, Bruce Bartholow, Farzadfar, Farshad, Fernandes, Joao C, Fürst, Thomas, Gibney, Katherine B, Gilmour, Stuart, Goodridge, Amador, Hankey, Graeme J, Hao, Yuantao, Harikrishnan, Sivadasanpillai, Heckbert, Susan R, Horita, Nobuyuki, Htike, Maung Maung Than, Jahanmehr, Nader, Jayatilleke, Achala Upendra, Jibat, Tariku, Khader, Yousef Saleh, Khalil, Ibrahim A, Kudom, Andreas A, Lam, Hilton, Larsson, Anders, Latif, Asma Abdul, Levi, Miriam, Lucas, Robyn M, Martinez-Raga, Jose, Marzan, Melvin Barrientos, Massano, João, Matzopoulos, Richard, Melaku, Yohannes Adama, Mock, Charles N, Mohan, Viswanathan, Montero, Pablo, Morawska, Lidia, Mori, Rintaro, Musa, Kamarul Imran, Ngalesoni, Frida Namnyak, de Dieu Ngirabega, Jean, Nyakarahuka, Luke, Osman, Majdi, Papachristou, Christina, Park, Eun-Kee, Park, Jae-Hyun, Patten, Scott B, Pereira, David M, Phillips, Michael Robert, Rahman, Mohammad Hifz Ur, Rao, Puja, Rao, Sowmya R, Rehm, Jürgen, Remuzzi, Giuseppe, Ronfani, Luca, Sartorius, Benn, Schwebel, David C, Sharma, Rajesh, Shen, Jiabin, Singh, Jasvinder A, Sposato, Luciano A, Takahashi, Ken, Thomson, Alan J, Tirschwell, David L, Traebert, Jefferson, Vasankari, Tommi, Wallin, Mitchell T, Wong, John Q, Yan, Lijing L, Yaseri, Mehdi, Zonies, David, Vos, Theo

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Global, regional, and national age–sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease St... von 2013 Mortality And Causes of Death Collaborators, Gbd, Aboyans, Victor

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Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990–2015: a systematic analysis for the Glo... von Arora, Megha, Bhutta, Zulfiqar A, Casey, Daniel C, Charlson, Fiona J, Coggeshall, Megan, Gething, Peter W, Kutz, Michael J, Mensah, George A, Naghavi, Mohsen, Nsoesie, Elaine, Rankin, Zane, Reinig, Nikolas, Troeger, Chris, Truelsen, Thomas, Abu-Raddad, Laith J, Adsuar, José C, Agardh, Emilie Elisabet, Al-Aly, Ziyad, Alam, Khurshid, Alkerwi, Ala'a, Alvis-Guzman, Nelson, Anderson, Gregory M, Artaman, Al, Awasthi, Ashish, Banerjee, Amitava, Barker-Collo, Suzanne L, Bennett, Derrick A, Betsu, Balem Demtsu, Bikbov, Boris, Abdulhak, Aref A Bin, Boufous, Soufiane, Bourne, Rupert R A, Breitborde, Nicholas J K, Calabria, Bianca, Campos-Nonato, Ismael Ricardo, Cárdenas, Rosario, Christensen, Hanne, Colomar, Mercedes, das Neves, José, Dubey, Manisha, Esteghamati, Alireza, Fahimi, Saman, Farinha, Carla Sofia e Sa, Farvid, Maryam S, Frostad, Joseph, Gabbe, Belinda, Gibney, Katherine B, Goodridge, Amador, Hailu, Alemayehu Desalegne, Haro, Josep Maria, Hassen, Tahir Ahmed, Huang, Hsiang, Idrisov, Bulat T, Jauregui, Alejandra, Jayatilleke, Achala Upendra, Jin, Ye, Kalkonde, Yogeshwar, Keiyoro, Peter Njenga, Kim, Yun Jin, Koyanagi, Ai, Bicer, Burcu Kucuk, Leung, Ricky, Looker, Katharine J, Lotufo, Paulo A, Malta, Deborah Carvalho, Marcenes, Wagner, Martinez-Raga, Jose, Mayosi, Bongani M, Hernandez, Julio Cesar Montañez, Mori, Rintaro, Mumford, John Everett, Pete, Patrick Martial Nkamedjie, Oladimeji, Olanrewaju, Olusanya, Jacob Olusegun, Park, Eun-Kee, Piel, Frédéric B, Qorbani, Mostafa, Reitsma, Marissa B, Remuzzi, Giuseppe, Shaikh, Masood Ali, Sharma, Rajesh, Singh, Jasvinder A, Skirbekk, Vegard, Søreide, Kjetil, Stroumpoulis, Konstantinos, Sur, Patrick J, Tanne, David, Ao, Braden J Te, Terkawi, Abdullah Sulieman, Thomson, Alan J, Thorne-Lyman, Andrew L, Thurston, George D, Topor-Madry, Roman, Tuzcu, Emin Murat, Uthman, Olalekan A, Vlassov, Vasiliy Victorovich, Wijeratne, Tissa, Yan, Lijing L, Yano, Yuichiro, Lopez, Alan D

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Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic anal... von Degenhardt, Louisa, Erskine, Holly, Ferrari, Alize J, Fitzmaurice, Christina, Graetz, Nicholas, Hansen, Gillian M, Laurie, Evan, Liang, Xiofeng, Ortblad, Katrina, Sandar, Logan, Abraham, Jerry P, Abraham, Biju, Abubakar, Ibrahim, Abu-Rmeileh, Niveen ME, Achoki, Tom, Ademi, Zanfina, Alam, Sayed Saidul, Albittar, Mohammed I, Alemu, Zewdie A, Alla, Francois, Anderson, Benjamin O, Antonio, Carl Abelardo T, Balalla, Shivanthi, Barquera, Simon, Basu, Sanjay, Basu, Arindam, Beghi, Ettore, Bell, Michelle L, Bensenor, Isabela M, Borges, Guilherme, Boyers, Lindsay N, Briggs, Adam DM, Buchbinder, Rachelle, Burnett, Richard, Campuzano, Julio C, Catala-Lopez, Ferran, Chang, Jung-Chen, Christophi, Costas A, Dandona, Lalit, Deribe, Kebede, Fay, Derek FJ, Fowkes, F Gerry R, Garcia-Guerra, Francisco A, Gibney, Katherine B, Gona, Philimon, Gouda, Hebe N, Hagan, Holly, Pi, Ileana B Heredia, Hoy, Damian G, Huang, John J, Husseini, Abdullatif, Jonas, Jost B, Karimkhani, Chante, Khan, Gulfaraz, Kieling, Christian, Knibbs, Luke, Lan, Qing, Lim, Stephen, Lind, Margaret, Lindsay, M Patrice, Lipshultz, Steven E, Low, Nicola, Lyons, Ronan A, Mackay, Mark T, Malekzadeh, Reza, Mapoma, Christopher C, McKee, Martin, Mehndiratta, Man Mohan, Miller, Ted R, Mills, Edward J, Moturi, Wilkister N, Moyer, Madeline, Naghavi, Paria, Nand, Devina, Ng, Marie, Nhung, Nguyen T, Norrving, Bo, Nyakarahuka, Luke, Pereira, David M, Peterson, Carrie B, Remuzzi, Giuseppe, Riccio, Patricia M, Richardson, Lee, Rojas-Rueda, David, Scarborough, Peter, Seedat, Soraya, Shackelford, Katya, She, Jun, Shibuya, Kenji, Shinohara, Yukito, Sindi, Shireen, Stroumpoulis, Konstantinos, Thomas, Elissa, Thrift, Amanda G, Traebert, Jefferson, Wilkinson, James D, Woldeyohannes, Solomon M, Xu, Gelin, Yentur, Gokalp K, Zhang, Yong

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The influence of environmental variability on the biogeography of coccolithophores and diatoms in the Great Calcite Belt von Smith, Helen E. K, Poulton, Alex J, Garley, Rebecca, Hopkins, Jason, Lubelczyk, Laura C, Drapeau, Dave T, Rauschenberg, Sara, Twining, Ben S, Bates, Nicholas R, Balch, William M

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Assessment of novel vaccination regimens using viral vectored liver stage malaria vaccines encoding ME-TRAP von Bliss, Carly M., Bowyer, Georgina, Anagnostou, Nicholas A., Havelock, Tom, Snudden, Claudia M., Davies, Huw, de Cassan, Simone C., Grobbelaar, Amy, Lawrie, Alison M., Venkatraman, Navin, Poulton, Ian D., Roberts, Rachel, Mange, Pooja B., Choudhary, Prateek, Faust, Saul N., Colloca, Stefano, Gilbert, Sarah C., Nicosia, Alfredo, Hill, Adrian V. S., Ewer, Katie J.

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Pandemic 2009 H1N1 Influenza Venus reporter virus reveals broad diversity of MHC class II-positive antigen-bearing cells following infection in vivo von DiPiazza, Anthony, Nogales, Aitor, Poulton, Nicholas, Wilson, Patrick C., Martínez-Sobrido, Luis, Sant, Andrea J.

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Resource profile and user guide of the Polygenic Index Repository von Becker, Joel, Burik, Casper A. P., Goldman, Grant, Wang, Nancy, Jayashankar, Hariharan, Bennett, Michael, Belsky, Daniel W., Karlsson Linnér, Richard, Ahlskog, Rafael, Kleinman, Aaron, Hinds, David A., Caspi, Avshalom, Corcoran, David L., Moffitt, Terrie E., Poulton, Richie, Sugden, Karen, Williams, Benjamin S., Harris, Kathleen Mullan, Steptoe, Andrew, Ajnakina, Olesya, Milani, Lili, Esko, Tõnu, Iacono, William G., McGue, Matt, Magnusson, Patrik K. E., Mallard, Travis T., Harden, K. Paige, Tucker-Drob, Elliot M., Herd, Pamela, Freese, Jeremy, Young, Alexander, Beauchamp, Jonathan P., Koellinger, Philipp D., Oskarsson, Sven, Johannesson, Magnus, Visscher, Peter M., Meyer, Michelle N., Laibson, David, Cesarini, David, Benjamin, Daniel J., Turley, Patrick, Okbay, Aysu

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