Diverse drug-resistance mechanisms can emerge from drug-tolerant cancer persister cells von Ramirez, Michael, Rajaram, Satwik, Steininger, Robert J., Osipchuk, Daria, Roth, Maike A., Morinishi, Leanna S., Evans, Louise, Ji, Weiyue, Hsu, Chien-Hsiang, Thurley, Kevin, Wei, Shuguang, Zhou, Anwu, Koduru, Prasad R., Posner, Bruce A., Wu, Lani F., Altschuler, Steven J.

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Systematic Identification of Molecular Subtype-Selective Vulnerabilities in Non-Small-Cell Lung Cancer von Kim, Hyun Seok, Mendiratta, Saurabh, Kim, Jiyeon, Pecot, Chad Victor, Larsen, Jill E., Zubovych, Iryna, Seo, Bo Yeun, Kim, Jimi, Eskiocak, Banu, Chung, Hannah, McMillan, Elizabeth, Wu, Sherry, De Brabander, Jef, Komurov, Kakajan, Toombs, Jason E., Wei, Shuguang, Peyton, Michael, Williams, Noelle, Gazdar, Adi F., Posner, Bruce A., Brekken, Rolf A., Sood, Anil K., Deberardinis, Ralph J., Roth, Michael G., Minna, John D., White, Michael A.

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Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan von Wang, Chensu, Niederstrasser, Hanspeter, Douglas, Peter M., Lin, Rueyling, Jaramillo, Juan, Li, Yang, Oswald, Nathaniel W., Zhou, Anwu, McMillan, Elizabeth A., Mendiratta, Saurabh, Wang, Zhaohui, Zhao, Tian, Lin, Zhiqaing, Luo, Min, Huang, Gang, Brekken, Rolf A., Posner, Bruce A., MacMillan, John B., Gao, Jinming, White, Michael A.

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ZNF281 enhances cardiac reprogramming by modulating cardiac and inflammatory gene expression von Zhou, Huanyu, Morales, Maria Gabriela, Hashimoto, Hisayuki, Dickson, Matthew E, Song, Kunhua, Ye, Wenduo, Kim, Min S, Niederstrasser, Hanspeter, Wang, Zhaoning, Chen, Beibei, Posner, Bruce A, Bassel-Duby, Rhonda, Olson, Eric N

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TBK1 Provides Context-Selective Support of the Activated AKT/mTOR Pathway in Lung Cancer von Cooper, Jonathan M, Ou, Yi-Hung, McMillan, Elizabeth A, Vaden, Rachel M, Zaman, Aubhishek, Bodemann, Brian O, Makkar, Gurbani, Posner, Bruce A, White, Michael A

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SMARCA4-inactivating mutations increase sensitivity to Aurora kinase A inhibitor VX-680 in non-small cell lung cancers von Tagal, Vural, Wei, Shuguang, Zhang, Wei, Brekken, Rolf A., Posner, Bruce A., Peyton, Michael, Girard, Luc, Hwang, TaeHyun, Wheeler, David A., Minna, John D., White, Michael A., Gazdar, Adi F., Roth, Michael G.

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Benzoxazole-derivatives enhance progranulin expression and reverse the aberrant lysosomal proteome caused by GRN haploinsufficiency von Tesla, Rachel, Guhl, Charlotte, Werthmann, Gordon C., Dixon, Danielle, Cenik, Basar, Addepalli, Yesu, Liang, Jue, Fass, Daniel M., Rosenthal, Zachary, Haggarty, Stephen J., Williams, Noelle S., Posner, Bruce A., Ready, Joseph M., Herz, Joachim

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HORMAD1 Is a Negative Prognostic Indicator in Lung Adenocarcinoma and Specifies Resistance to Oxidative and Genotoxic Stress von Nichols, Brandt A, Oswald, Nathaniel W, McMillan, Elizabeth A, McGlynn, Kathleen, Yan, Jingsheng, Kim, Min S, Saha, Janapriya, Mallipeddi, Prema L, LaDuke, Sydnie A, Villalobos, Pamela A, Rodriguez-Canales, Jaime, Wistuba, Ignacio I, Posner, Bruce A, Davis, Anthony J, Minna, John D, MacMillan, John B, Whitehurst, Angelique W

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Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase von Theodoropoulos, Panayotis C, Gonzales, Stephen S, Winterton, Sarah E, Rodriguez-Navas, Carlos, McKnight, John S, Morlock, Lorraine K, Hanson, Jordan M, Cross, Bethany, Owen, Amy E, Duan, Yingli, Moreno, Jose R, Lemoff, Andrew, Mirzaei, Hamid, Posner, Bruce A, Williams, Noelle S, Ready, Joseph M, Nijhawan, Deepak

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Precursor-Directed Generation of Amidine Containing Ammosamide Analogs: Ammosamides E-P von Pan, Ende, Oswald, Nathaniel W, Legako, Aaron G, Life, Janie M, Posner, Bruce A, Macmillan, John B

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A highly-sensitive high throughput assay for dynamin's basal GTPase activity von Mohanakrishnan, Aparna, Tran, Triet Vincent M, Kumar, Meera, Chen, Hong, Posner, Bruce A, Schmid, Sandra L

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Small molecule glucagon release inhibitors with activity in human islets von Kalwat, Michael A, Rodrigues-Dos-Santos, Karina, Binns, Derk D, Wei, Shuguang, Zhou, Anwu, Evans, Matthew R, Posner, Bruce A, Roth, Michael G, Cobb, Melanie H

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Interaction between the autophagy protein Beclin 1 and Na+, K+-ATPase during starvation, exercise, and ischemia von Fernandez, Alvaro F., Liu, Yang, Ginet, Vanessa, Shi, Mingjun, Nah, Jihoon, Zou, Zhongju, Zhou, Anwu, Posner, Bruce A., Xiao, Guanghua, Tanguy, Marion, Paradis, Valerie, Sadoshima, Junichi, Rautou, Pierre-Emmanuel, Puyal, Julien, Hu, Ming Chang, Levine, Beth

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Author Correction: Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan von Wang, Chensu, Niederstrasser, Hanspeter, Douglas, Peter M., Lin, Rueyling, Jaramillo, Juan, Li, Yang, Oswald, Nathaniel W., Zhou, Anwu, McMillan, Elizabeth A., Mendiratta, Saurabh, Wang, Zhaohui, Zhao, Tian, Lin, Zhiqaing, Luo, Min, Huang, Gang, Brekken, Rolf A., Posner, Bruce A., MacMillan, John B., Gao, Jinming, White, Michael A.

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Enhanced HTS Hit Selection via a Local Hit Rate Analysis von Posner, Bruce A, Xi, Hualin, Mills, James E. J

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XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer von Kim, Jimi, McMillan, Elizabeth, Kim, Hyun Seok, Venkateswaran, Niranjan, Makkar, Gurbani, Rodriguez-Canales, Jaime, Villalobos, Pamela, Neggers, Jasper Edgar, Mendiratta, Saurabh, Wei, Shuguang, Landesman, Yosef, Senapedis, William, Baloglu, Erkan, Chow, Chi-Wan B., Frink, Robin E., Gao, Boning, Roth, Michael, Minna, John D., Daelemans, Dirk, Wistuba, Ignacio I., Posner, Bruce A., Scaglioni, Pier Paolo, White, Michael A.

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A cholesterol-binding bacterial toxin provides a strategy for identifying a specific Scap inhibitor that blocks lipid synthesis in animal cells von Xu, Shimeng, Smothers, Jared C, Rye, Daphne, Endapally, Shreya, Chen, Hong, Li, Shili, Liang, Guosheng, Kinnebrew, Maia, Rohatgi, Rajat, Posner, Bruce A, Radhakrishnan, Arun

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Targeting ESR1 mutation–induced transcriptional addiction in breast cancer with BET inhibition von Udden, Sm N., Wang, Qian, Kumar, Sunil, Malladi, Venkat S., Wu, Shwu-Yuan, Wei, Shuguang, Posner, Bruce A., Geboers, Sophie, Williams, Noelle S., Liu, Yulun, Sharma, Jayesh K., Mani, Ram S., Malladi, Srinivas, Parra, Karla, Hofstad, Mia, Raj, Ganesh V., Larios, Jose M., Jagsi, Reshma, Wicha, Max S., Park, Ben Ho, Gupta, Gaorav P., Chinnaiyan, Arul M., Chiang, Cheng-Ming, Alluri, Prasanna G.

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1,25-Dihydroxyvitamin D 3 enhances glucose-stimulated insulin secretion in mouse and human islets: a role for transcriptional regulation of voltage-gated calcium channels by the vi... von Kjalarsdottir, Lilja, Tersey, Sarah A, Vishwanath, Mridula, Chuang, Jen-Chieh, Posner, Bruce A, Mirmira, Raghavendra G, Repa, Joyce J

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Improving drug discovery with high-content phenotypic screens by systematic selection of reporter cell lines von Kang, Jungseog, Hsu, Chien-Hsiang, Wu, Qi, Liu, Shanshan, Coster, Adam D, Posner, Bruce A, Altschuler, Steven J, Wu, Lani F

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