The functional consequences of intron retention: Alternative splicing coupled to NMD as a regulator of gene expression von Ge, Ying, Porse, Bo T.

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Regulation of Axon Guidance by Compartmentalized Nonsense-Mediated mRNA Decay von Colak, Dilek, Ji, Sheng-Jian, Porse, Bo T., Jaffrey, Samie R.

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Quantitative single-cell proteomics as a tool to characterize cellular hierarchies von Schoof, Erwin M., Furtwängler, Benjamin, Üresin, Nil, Rapin, Nicolas, Savickas, Simonas, Gentil, Coline, Lechman, Eric, Keller, Ulrich auf dem, Dick, John E., Porse, Bo T.

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UPF2-Dependent Nonsense-Mediated mRNA Decay Pathway Is Essential for Spermatogenesis by Selectively Eliminating Longer 3'UTR Transcripts von Bao, Jianqiang, Vitting-Seerup, Kristoffer, Waage, Johannes, Tang, Chong, Ge, Ying, Porse, Bo T, Yan, Wei

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BloodSpot: a database of gene expression profiles and transcriptional programs for healthy and malignant haematopoiesis von Bagger, Frederik Otzen, Sasivarevic, Damir, Sohi, Sina Hadi, Laursen, Linea Gøricke, Pundhir, Sachin, Sønderby, Casper Kaae, Winther, Ole, Rapin, Nicolas, Porse, Bo T

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EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas von Mohammad, Faizaan, Weissmann, Simon, Leblanc, Benjamin, Pandey, Deo P, Højfeldt, Jonas W, Comet, Itys, Zheng, Chunqin, Johansen, Jens Vilstrup, Rapin, Nicolas, Porse, Bo T, Tvardovskiy, Andrey, Jensen, Ole N, Olaciregui, Nagore G, Lavarino, Cinzia, Suñol, Mariona, de Torres, Carmen, Mora, Jaume, Carcaboso, Angel M, Helin, Kristian

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Loss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis von Rasmussen, Kasper D, Jia, Guangshuai, Johansen, Jens V, Pedersen, Marianne T, Rapin, Nicolas, Bagger, Frederik O, Porse, Bo T, Bernard, Olivier A, Christensen, Jesper, Helin, Kristian

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Myelodysplastic syndrome patient-derived xenografts: from no options to many von Come, Christophe, Balhuizen, Alexander, Bonnet, Dominique, Porse, Bo T.

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Exploration of cell state heterogeneity using single-cell proteomics through sensitivity-tailored data-independent acquisition von Petrosius, Valdemaras, Aragon-Fernandez, Pedro, Üresin, Nil, Kovacs, Gergo, Phlairaharn, Teeradon, Furtwängler, Benjamin, Op De Beeck, Jeff, Skovbakke, Sarah L., Goletz, Steffen, Thomsen, Simon Francis, Keller, Ulrich auf dem, Natarajan, Kedar N., Porse, Bo T., Schoof, Erwin M.

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Comparing cancer vs normal gene expression profiles identifies new disease entities and common transcriptional programs in AML patients von Rapin, Nicolas, Bagger, Frederik Otzen, Jendholm, Johan, Mora-Jensen, Helena, Krogh, Anders, Kohlmann, Alexander, Thiede, Christian, Borregaard, Niels, Bullinger, Lars, Winther, Ole, Theilgaard-Mönch, Kim, Porse, Bo T.

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Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block von Nerlov, Claus, Kirstetter, Peggy, Anderson, Kristina, Porse, Bo T, Jacobsen, Sten Eirik W

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The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells von Bracken, Adrian P, Kleine-Kohlbrecher, Daniela, Dietrich, Nikolaj, Pasini, Diego, Gargiulo, Gaetano, Beekman, Chantal, Theilgaard-Mönch, Kim, Minucci, Saverio, Porse, Bo T, Marine, Jean-Christophe, Hansen, Klaus H, Helin, Kristian

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The histone demethylase KDM5C functions as a tumor suppressor in AML by repression of bivalently marked immature genes von Trempenau, Mette Louise, Schuster, Mikkel Bruhn, Pundhir, Sachin, Pereira, Mafalda Araujo, Kalvisa, Adrija, Tapia, Marta, Su, Jinyu, Ge, Ying, de Boer, Bauke, Balhuizen, Alexander, Bagger, Frederik Otzen, Shliaha, Pavel, Sroczynska, Patrycja, Walfridsson, Julian, Grønbæk, Kirsten, Theilgaard-Mönch, Kim, Jensen, Ole N., Helin, Kristian, Porse, Bo T.

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UPF2, a nonsense-mediated mRNA decay factor, is required for prepubertal Sertoli cell development and male fertility by ensuring fidelity of the transcriptome von Bao, Jianqiang, Tang, Chong, Yuan, Shuiqiao, Porse, Bo T, Yan, Wei

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TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression von Heyes, Elizabeth, Wilhelmson, Anna S., Wenzel, Anne, Manhart, Gabriele, Eder, Thomas, Schuster, Mikkel B., Rzepa, Edwin, Pundhir, Sachin, D’Altri, Teresa, Frank, Anne-Katrine, Gentil, Coline, Woessmann, Jakob, Schoof, Erwin M., Meggendorfer, Manja, Schwaller, Jürg, Haferlach, Torsten, Grebien, Florian, Porse, Bo T.

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C/EBPα is required for long-term self-renewal and lineage priming of hematopoietic stem cells and for the maintenance of epigenetic configurations in multipotent progenitors von Hasemann, Marie S, Lauridsen, Felicia K B, Waage, Johannes, Jakobsen, Janus S, Frank, Anne-Katrine, Schuster, Mikkel B, Rapin, Nicolas, Bagger, Frederik O, Hoppe, Philipp S, Schroeder, Timm, Porse, Bo T

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HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis von Bagger, Frederik Otzen, Rapin, Nicolas, Theilgaard-Mönch, Kim, Kaczkowski, Bogumil, Thoren, Lina A, Jendholm, Johan, Winther, Ole, Porse, Bo T

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Allelic methylation levels of the noncoding VTRNA2-1 located on chromosome 5q31.1 predict outcome in AML von Treppendahl, Marianne Bach, Qiu, Xiangning, Søgaard, Alexandra, Yang, Xiaojing, Nandrup-Bus, Cecilie, Hother, Christoffer, Andersen, Mette Klarskov, Kjeldsen, Lars, Möllgaard, Lars, Hellström-Lindberg, Eva, Jendholm, Johan, Porse, Bo T., Jones, Peter A., Liang, Gangning, Grønbæk, Kirsten

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Proinflammatory cytokines suppress nonsense-mediated RNA decay to impair regulated transcript isoform processing in pancreatic β cells von Ghiasi, Seyed M, Marchetti, Piero, Piemonti, Lorenzo, Nielsen, Jens H, Porse, Bo T, Mandrup-Poulsen, Thomas, Rutter, Guy A

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Lipocalin 2 is protective against E. coli pneumonia von Wu, Hong, Santoni-Rugiu, Eric, Ralfkiaer, Elisabeth, Porse, Bo T, Moser, Claus, Høiby, Niels, Borregaard, Niels, Cowland, Jack B

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