Polycyclic xanthone natural products: structure, biological activity and chemical synthesis von Winter, Dana K, Sloman, David L, Porco Jr, John A

Volltext

Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus von Whitesell, Luke, Robbins, Nicole, Huang, David S., McLellan, Catherine A., Shekhar-Guturja, Tanvi, LeBlanc, Emmanuelle V., Nation, Catherine S., Hui, Raymond, Hutchinson, Ashley, Collins, Cathy, Chatterjee, Sharanya, Trilles, Richard, Xie, Jinglin L., Krysan, Damian J., Lindquist, Susan, Porco, John A., Tatu, Utpal, Brown, Lauren E., Pizarro, Juan, Cowen, Leah E.

Volltext

The MYCN 5′ UTR as a therapeutic target in neuroblastoma von Volegova, Marina P., Brown, Lauren E., Banerjee, Ushashi, Dries, Ruben, Sharma, Bandana, Kennedy, Alyssa, Porco, John A., George, Rani E.

Volltext

Catalytic Enantioselective Alkylative Dearomatization−Annulation: Total Synthesis and Absolute Configuration Assignment of Hyperibone K von Qi, Ji, Beeler, Aaron B., Zhang, Qiang, Porco, Jr, John A.

Volltext

Enantioselective Synthesis of the Complex Rocaglate (-)-Silvestrol von Gerard, Baudouin, Cencic, Regina, Pelletier, Jerry, Porco, John A. Jr

Volltext

Photochemical Approaches to Complex Chemotypes: Applications in Natural Product Synthesis von Kärkäs, Markus D, Porco, John A, Stephenson, Corey R. J

Volltext

Biomimetic Photocycloaddition of 3-Hydroxyflavones: Synthesis and Evaluation of Rocaglate Derivatives as Inhibitors of Eukaryotic Translation von Roche, Stéphane P, Cencic, Regina, Pelletier, Jerry, Porco, John A. Jr

Volltext

Dearomatization Strategies in the Synthesis of Complex Natural Products von Roche, Stéphane P., Porco Jr, John A.

Volltext

Oxo-aglaiastatin-Mediated Inhibition of Translation Initiation von Itoua Maïga, Rayelle, Cencic, Regina, Chu, Jennifer, Waller, Daniel D., Brown, Lauren E., Devine, William G., Zhang, Wenhan, Sebag, Michael, Porco Jr, John A., Pelletier, Jerry

Volltext

Synthesis and Biological Evaluation of ABCD Ring Fragments of the Kibdelones von Sloman, David L, Mitasev, Branko, Scully, Stephen S, Beutler, John A, Porco, John A. Jr

Volltext

RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer von Wolfe, Andrew L., Singh, Kamini, Zhong, Yi, Drewe, Philipp, Rajasekhar, Vinagolu K., Sanghvi, Viraj R., Mavrakis, Konstantinos J., Jiang, Man, Roderick, Justine E., Van der Meulen, Joni, Schatz, Jonathan H., Rodrigo, Christina M., Zhao, Chunying, Rondou, Pieter, de Stanchina, Elisa, Teruya-Feldstein, Julie, Kelliher, Michelle A., Speleman, Frank, Porco, John A., Pelletier, Jerry, Rätsch, Gunnar, Wendel, Hans-Guido

Volltext

Triple-Dearomative Photocycloaddition: A Strategy to Construct Caged Molecular Frameworks von Ji, Kaijie, Parthiban, Jayachandran, Jockusch, Steffen, Sivaguru, Jayaraman, Porco, John A.

Volltext

Asymmetric Synthesis of Nidulalin A and Nidulaxanthone A: Selective Carbonyl Desaturation Using an Oxoammonium Salt von Ji, Kaijie, Johnson, Richard P., McNeely, James, Al Faruk, Md, Porco, John A.

Volltext

Total Syntheses of Secalonic Acids A and D von Qin, Tian, Porco Jr, John A.

Volltext

Discovery of new antimalarial chemotypes through chemical methodology and library development von Brown, Lauren E, Chih-Chien Cheng, Ken, Wei, Wan-Guo, Yuan, Pingwei, Dai, Peng, Trilles, Richard, Ni, Feng, Yuan, Jing, MacArthur, Ryan, Guha, Rajarshi, Johnson, Ronald L, Su, Xin-zhuan, Dominguez, Melissa M, Snyder, John K, Beeler, Aaron B, Schaus, Scott E, Inglese, James, Porco, John A. Jr

Volltext

Studies toward the Synthesis of (−)-Zampanolide: Preparation of the Macrocyclic Core von Troast, Dawn M., Yuan, Jiayi, Porco Jr, John A.

Volltext

BRCA mutational status shapes the stromal microenvironment of pancreatic cancer linking clusterin expression in cancer associated fibroblasts with HSF1 signaling von Shaashua, Lee, Ben-Shmuel, Aviad, Pevsner-Fischer, Meirav, Friedman, Gil, Levi-Galibov, Oshrat, Nandakumar, Subhiksha, Barki, Debra, Nevo, Reinat, Brown, Lauren E., Zhang, Wenhan, Stein, Yaniv, Lior, Chen, Kim, Han Sang, Bojmar, Linda, Jarnagin, William R., Lecomte, Nicolas, Mayer, Shimrit, Stok, Roni, Bishara, Hend, Hamodi, Rawand, Levy-Lahad, Ephrat, Golan, Talia, Porco, John A., Iacobuzio-Donahue, Christine A., Schultz, Nikolaus, Tuveson, David A., Lyden, David, Kelsen, David, Scherz-Shouval, Ruth

Volltext

Asymmetric, Stereodivergent Synthesis of (−)-Clusianone Utilizing a Biomimetic Cationic Cyclization von Boyce, Jonathan H., Porco Jr, John A.

Volltext

CRISPR-Mediated Drug-Target Validation Reveals Selective Pharmacological Inhibition of the RNA Helicase, eIF4A von Chu, Jennifer, Galicia-Vázquez, Gabriela, Cencic, Regina, Mills, John R., Katigbak, Alexandra, Porco, John A., Pelletier, Jerry

Volltext

An oxindole efflux inhibitor potentiates azoles and impairs virulence in the fungal pathogen Candida auris von Iyer, Kali R., Camara, Kaddy, Daniel-Ivad, Martin, Trilles, Richard, Pimentel-Elardo, Sheila M., Fossen, Jen L., Marchillo, Karen, Liu, Zhongle, Singh, Shakti, Muñoz, José F., Kim, Sang Hu, Porco, John A., Cuomo, Christina A., Williams, Noelle S., Ibrahim, Ashraf S., Edwards, John E., Andes, David R., Nodwell, Justin R., Brown, Lauren E., Whitesell, Luke, Robbins, Nicole, Cowen, Leah E.

Volltext