Physiological release of endogenous tau is stimulated by neuronal activity von Pooler, Amy M, Phillips, Emma C, Lau, Dawn H W, Noble, Wendy, Hanger, Diane P

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A role for tau at the synapse in Alzheimer's disease pathogenesis von Pooler, Amy M., Noble, Wendy, Hanger, Diane P.

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Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer's disease von Pooler, Amy M, Polydoro, Manuela, Maury, Eduardo A, Nicholls, Samantha B, Reddy, Snigdha M, Wegmann, Susanne, William, Christopher, Saqran, Lubna, Cagsal-Getkin, Ozge, Pitstick, Rose, Beier, David R, Carlson, George A, Spires-Jones, Tara L, Hyman, Bradley T

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Reduced number of axonal mitochondria and tau hypophosphorylation in mouse P301L tau knockin neurons von Rodríguez-Martín, Teresa, Pooler, Amy M, Lau, Dawn H.W, Mórotz, Gábor M, De Vos, Kurt J, Gilley, Jonathan, Coleman, Michael P, Hanger, Diane P

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Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer’s disease model von Polydoro, Manuela, Dzhala, Volodymyr I., Pooler, Amy M., Nicholls, Samantha B., McKinney, A. Patrick, Sanchez, Laura, Pitstick, Rose, Carlson, George A., Staley, Kevin J., Spires-Jones, Tara L., Hyman, Bradley T.

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Propagation of tau pathology in Alzheimer's disease: identification of novel therapeutic targets von Pooler, Amy M, Polydoro, Manuela, Wegmann, Susanne, Nicholls, Samantha B, Spires-Jones, Tara L, Hyman, Bradley T

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Mislocalization of neuronal tau in the absence of tangle pathology in phosphomutant tau knockin mice von Gilley, Jonathan, Ando, Kunie, Seereeram, Anjan, Rodríguez-Martín, Teresa, Pooler, Amy M, Sturdee, Laura, Anderton, Brian H, Brion, Jean-Pierre, Hanger, Diane P, Coleman, Michael P

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Persistent repression of tau in the brain using engineered zinc finger protein transcription factors von Wegmann, Susanne, DeVos, Sarah L., Zeitler, Bryan, Marlen, Kimberly, Bennett, Rachel E., Perez-Rando, Marta, MacKenzie, Danny, Yu, Qi, Commins, Caitlin, Bannon, Riley N., Corjuc, Bianca T., Chase, Alison, Diez, Lisa, Nguyen, Hoang-Oanh B., Hinkley, Sarah, Zhang, Lei, Goodwin, Alicia, Ledeboer, Annemarie, Lam, Stephen, Ankoudinova, Irina, Hung Tran, Scarlott, Nicholas, Amora, Rainier, Surosky, Richard, Miller, Jeffrey C., Robbins, Ashley B., Rebar, Edward J., Urnov, Fyodor D., Holmes, Michael C., Pooler, Amy M., Riley, Brigit, Zhang, H. Steve, Hyman, Bradley T.

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3-hydroxy-3-methylglutaryl co-enzyme A reductase inhibitor pravastatin enhances neurite outgrowth in hippocampal neurons von Pooler, Amy M, Xi, Shijun C, Wurtman, Richard J

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Apolipoprotein E4 Expression Causes Gain of Toxic Function in Isogenic Human Induced Pluripotent Stem Cell-Derived Endothelial Cells von Rieker, Claus, Migliavacca, Eugenia, Vaucher, Angélique, Baud, Gilles, Marquis, Julien, Charpagne, Aline, Hegde, Nagabhooshan, Guignard, Laurence, McLachlan, Michael, Pooler, Amy M

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Dynamic association of tau with neuronal membranes is regulated by phosphorylation von Pooler, Amy M, Usardi, Alessia, Evans, Catherine J, Philpott, Karen L, Noble, Wendy, Hanger, Diane P

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Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity von Wegmann, Susanne, Maury, Eduardo A, Kirk, Molly J, Saqran, Lubna, Roe, Allyson, DeVos, Sarah L, Nicholls, Samantha, Fan, Zhanyun, Takeda, Shuko, Cagsal-Getkin, Ozge, William, Christopher M, Spires-Jones, Tara L, Pitstick, Rose, Carlson, George A, Pooler, Amy M, Hyman, Bradley T

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Progressive Neuronal Pathology and Synaptic Loss Induced by Prediabetes and Type 2 Diabetes in a Mouse Model of Alzheimer’s Disease von Ramos-Rodriguez, Juan Jose, Spires-Jones, Tara, Pooler, Amy M., Lechuga-Sancho, Alfonso Maria, Bacskai, Brian J., Garcia-Alloza, Monica

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Lateral Diffusion of the GABAB Receptor Is Regulated by the GABAB2 C Terminus von Pooler, Amy M., McIlhinney, R. A. Jeffrey

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Studying synapses in human brain with array tomography and electron microscopy von Kay, Kevin R, Smith, Colin, Wright, Ann K, Serrano-Pozo, Alberto, Pooler, Amy M, Koffie, Robert, Bastin, Mark E, Bak, Thomas H, Abrahams, Sharon, Kopeikina, Katherine J, McGuone, Declan, Frosch, Matthew P, Gillingwater, Thomas H, Hyman, Bradley T, Spires-Jones, Tara L

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Tyrosine phosphorylation of tau regulates its interactions with Fyn SH2 domains, but not SH3 domains, altering the cellular localization of tau von Usardi, Alessia, Pooler, Amy M, Seereeram, Anjan, Reynolds, C. Hugh, Derkinderen, Pascal, Anderton, Brian, Hanger, Diane P, Noble, Wendy, Williamson, Ritchie

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Membrane association and release of wild-type and pathological tau from organotypic brain slice cultures von Croft, Cara L, Wade, Matthew A, Kurbatskaya, Ksenia, Mastrandreas, Pavlina, Hughes, Martina M, Phillips, Emma C, Pooler, Amy M, Perkinton, Michael S, Hanger, Diane P, Noble, Wendy

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Critical residues involved in tau binding to fyn: implications for tau phosphorylation in Alzheimer's disease von Lau, Dawn H W, Hogseth, Marte, Phillips, Emma C, O'Neill, Michael J, Pooler, Amy M, Noble, Wendy, Hanger, Diane P

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Copines-1, -2, -3, -6 and -7 show different calcium-dependent intracellular membrane translocation and targeting von Perestenko, Pavel V, Pooler, Amy M, Noorbakhshnia, Maryam, Gray, Adrian, Bauccio, Charlotte, Jeffrey McIlhinney, Robert Andrew

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NUB1 modulation of GSK3β reduces tau aggregation von RICHET, Emma, POOLER, Amy M, RODRIGUEZ, Teresa, NOVOSELOV, Sergey S, SCHMIDTKE, Gunter, GROETTRUP, Marcus, HANGER, Diane P, CHEETHAM, Michael E, DER SPUR, Jacqueline Van

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