A Molecular Roadmap of Reprogramming Somatic Cells into iPS Cells von Polo, Jose M., Anderssen, Endre, Walsh, Ryan M., Schwarz, Benjamin A., Nefzger, Christian M., Lim, Sue Mei, Borkent, Marti, Apostolou, Effie, Alaei, Sara, Cloutier, Jennifer, Bar-Nur, Ori, Cheloufi, Sihem, Stadtfeld, Matthias, Figueroa, Maria Eugenia, Robinton, Daisy, Natesan, Sridaran, Melnick, Ari, Zhu, Jinfang, Ramaswamy, Sridhar, Hochedlinger, Konrad

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Class-Switch Recombination Occurs Infrequently in Germinal Centers von Roco, Jonathan A., Mesin, Luka, Binder, Sebastian C., Nefzger, Christian, Gonzalez-Figueroa, Paula, Canete, Pablo F., Ellyard, Julia, Shen, Qian, Robert, Philippe A., Cappello, Jean, Vohra, Harpreet, Zhang, Yang, Nowosad, Carla R., Schiepers, Arien, Corcoran, Lynn M., Toellner, Kai-Michael, Polo, Jose M., Meyer-Hermann, Michael, Victora, Gabriel D., Vinuesa, Carola G.

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Sox2 + Adult Stem and Progenitor Cells Are Important for Tissue Regeneration and Survival of Mice von Arnold, Katrin, Sarkar, Abby, Yram, Mary Anna, Polo, Jose M., Bronson, Rod, Sengupta, Sumitra, Seandel, Marco, Geijsen, Niels, Hochedlinger, Konrad

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A modular dCas9-SunTag DNMT3A epigenome editing system overcomes pervasive off-target activity of direct fusion dCas9-DNMT3A constructs von Pflueger, Christian, Tan, Dennis, Swain, Tessa, Nguyen, Trung, Pflueger, Jahnvi, Nefzger, Christian, Polo, Jose M, Ford, Ethan, Lister, Ryan

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Transcriptional signature in microglia associated with Aβ plaque phagocytosis von Grubman, Alexandra, Choo, Xin Yi, Chew, Gabriel, Ouyang, John F., Sun, Guizhi, Croft, Nathan P., Rossello, Fernando J., Simmons, Rebecca, Buckberry, Sam, Landin, Dulce Vargas, Pflueger, Jahnvi, Vandekolk, Teresa H., Abay, Zehra, Zhou, Yichen, Liu, Xiaodong, Chen, Joseph, Larcombe, Michael, Haynes, John M., McLean, Catriona, Williams, Sarah, Chai, Siew Yeen, Wilson, Trevor, Lister, Ryan, Pouton, Colin W., Purcell, Anthony W., Rackham, Owen J. L., Petretto, Enrico, Polo, Jose M.

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Highly Coordinated Proteome Dynamics during Reprogramming of Somatic Cells to Pluripotency von Hansson, Jenny, Rafiee, Mahmoud Reza, Reiland, Sonja, Polo, Jose M., Gehring, Julian, Okawa, Satoshi, Huber, Wolfgang, Hochedlinger, Konrad, Krijgsveld, Jeroen

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Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells von Wagers, Amy J, Eminli, Sarah, Evans, Todd, Liu, Susanna, Kulalert, Warakorn, Li, Yushan, Apostolou, Effie, Tan, Kah Yong, Natesan, Sridaran, Melnick, Ari, Polo, Jose M, Shioda, Toshi, Hochedlinger, Konrad, Stadtfeld, Matthias, Figueroa, Maria Eugenia

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Genome-wide Chromatin Interactions of the Nanog Locus in Pluripotency, Differentiation, and Reprogramming von Apostolou, Effie, Ferrari, Francesco, Walsh, Ryan M., Bar-Nur, Ori, Stadtfeld, Matthias, Cheloufi, Sihem, Stuart, Hannah T., Polo, Jose M., Ohsumi, Toshiro K., Borowsky, Mark L., Kharchenko, Peter V., Park, Peter J., Hochedlinger, Konrad

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A high-resolution map of human RNA translation von Chothani, Sonia P., Adami, Eleonora, Widjaja, Anissa A., Langley, Sarah R., Viswanathan, Sivakumar, Pua, Chee Jian, Zhihao, Nevin Tham, Harmston, Nathan, D’Agostino, Giuseppe, Whiffin, Nicola, Mao, Wang, Ouyang, John F., Lim, Wei Wen, Lim, Shiqi, Lee, Cheryl Q.E., Grubman, Alexandra, Chen, Joseph, Kovalik, J.P., Tryggvason, Karl, Polo, Jose M., Ho, Lena, Cook, Stuart A., Rackham, Owen J.L., Schafer, Sebastian

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A predictive computational framework for direct reprogramming between human cell types von Rackham, Owen J L, Firas, Jaber, Fang, Hai, Oates, Matt E, Holmes, Melissa L, Knaupp, Anja S, Suzuki, Harukazu, Nefzger, Christian M, Daub, Carsten O, Shin, Jay W, Petretto, Enrico, Forrest, Alistair R R, Hayashizaki, Yoshihide, Polo, Jose M, Gough, Julian

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Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells von Ohi, Yuki, Qin, Han, Hong, Chibo, Blouin, Laure, Polo, Jose M., Guo, Tingxia, Qi, Zhongxia, Downey, Sara L., Manos, Philip D., Rossi, Derrick J., Yu, Jingwei, Hebrok, Matthias, Hochedlinger, Konrad, Costello, Joseph F., Song, Jun S., Ramalho-Santos, Miguel

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Comprehensive characterization of distinct states of human naive pluripotency generated by reprogramming von Liu, Xiaodong, Nefzger, Christian M, Rossello, Fernando J, Chen, Joseph, Knaupp, Anja S, Firas, Jaber, Ford, Ethan, Pflueger, Jahnvi, Paynter, Jacob M, Chy, Hun S, O'Brien, Carmel M, Huang, Cheng, Mishra, Ketan, Hodgson-Garms, Margeaux, Jansz, Natasha, Williams, Sarah M, Blewitt, Marnie E, Nilsson, Susan K, Schittenhelm, Ralf B, Laslett, Andrew L, Lister, Ryan, Polo, Jose M

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Transient and Permanent Reconfiguration of Chromatin and Transcription Factor Occupancy Drive Reprogramming von Knaupp, Anja S., Buckberry, Sam, Pflueger, Jahnvi, Lim, Sue Mei, Ford, Ethan, Larcombe, Michael R., Rossello, Fernando J., de Mendoza, Alex, Alaei, Sara, Firas, Jaber, Holmes, Melissa L., Nair, Shalima S., Clark, Susan J., Nefzger, Christian M., Lister, Ryan, Polo, Jose M.

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High ploidy large cytoplasmic megakaryocytes are hematopoietic stem cells regulators and essential for platelet production von Heazlewood, Shen Y., Ahmad, Tanveer, Cao, Benjamin, Cao, Huimin, Domingues, Melanie, Sun, Xuan, Heazlewood, Chad K., Li, Songhui, Williams, Brenda, Fulton, Madeline, White, Jacinta F., Nebl, Tom, Nefzger, Christian M., Polo, Jose M., Kile, Benjamin T., Kraus, Felix, Ryan, Michael T., Sun, Yu B., Choong, Peter F. M., Ellis, Sarah L., Anko, Minna-Liisa, Nilsson, Susan K.

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Apicobasal RNA asymmetries regulate cell fate in the early mouse embryo von Hawdon, Azelle, Geoghegan, Niall D., Mohenska, Monika, Elsenhans, Anja, Ferguson, Charles, Polo, Jose M., Parton, Robert G., Zenker, Jennifer

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Identification of dynamic undifferentiated cell states within the male germline von La, Hue M., Mäkelä, Juho-Antti, Chan, Ai-Leen, Rossello, Fernando J., Nefzger, Christian M., Legrand, Julien M. D., De Seram, Mia, Polo, Jose M., Hobbs, Robin M.

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A Hybrid Mechanism of Action for BCL6 in B Cells Defined by Formation of Functionally Distinct Complexes at Enhancers and Promoters von Hatzi, Katerina, Jiang, Yanwen, Huang, Chuanxin, Garrett-Bakelman, Francine, Gearhart, Micah D., Giannopoulou, Eugenia G., Zumbo, Paul, Kirouac, Kevin, Bhaskara, Srividya, Polo, Jose M., Kormaksson, Matthias, MacKerell, Alexander D., Xue, Fengtian, Mason, Christopher E., Hiebert, Scott W., Prive, Gilbert G., Cerchietti, Leandro, Bardwell, Vivian J., Elemento, Olivier, Melnick, Ari

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Nicotinamide riboside attenuates age-associated metabolic and functional changes in hematopoietic stem cells von Sun, Xuan, Cao, Benjamin, Naval-Sanchez, Marina, Pham, Tony, Sun, Yu Bo Yang, Williams, Brenda, Heazlewood, Shen Y., Deshpande, Nikita, Li, Jinhua, Kraus, Felix, Rae, James, Nguyen, Quan, Yari, Hamed, Schröder, Jan, Heazlewood, Chad K., Fulton, Madeline, Hatwell-Humble, Jessica, Das Gupta, Kaustav, Kapetanovic, Ronan, Chen, Xiaoli, Sweet, Matthew J., Parton, Robert G., Ryan, Michael T., Polo, Jose M., Nefzger, Christian M., Nilsson, Susan K.

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The apparent loss of PRC2 chromatin occupancy as an artifact of RNA depletion von Healy, Evan, Zhang, Qi, Gail, Emma H., Agius, Samuel C., Sun, Guizhi, Bullen, Michael, Pandey, Varun, Das, Partha Pratim, Polo, Jose M., Davidovich, Chen

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Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity von Wang, Jueqiong, Farkas, Carlos, Benyoucef, Aissa, Carmichael, Catherine, Haigh, Katharina, Wong, Nick, Huylebroeck, Danny, Stemmler, Marc P., Brabletz, Simone, Brabletz, Thomas, Nefzger, Christian M., Goossens, Steven, Berx, Geert, Polo, Jose M., Haigh, Jody J.

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