Desmosomes at a glance von Perl, Abbey L, Pokorny, Jenny L, Green, Kathleen J

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WWP2 is an E3 ubiquitin ligase for PTEN von Maddika, Subbareddy, Chen, Junjie, Kavela, Sridhar, Rani, Neelam, Palicharla, Vivek Reddy, Pokorny, Jenny L, Sarkaria, Jann N

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Inhibition of multidrug resistance protein 1 (MRP1) improves chemotherapy drug response in primary and recurrent glioblastoma multiforme von Tivnan, Amanda, Zakaria, Zaitun, O'Leary, Caitrín, Kögel, Donat, Pokorny, Jenny L, Sarkaria, Jann N, Prehn, Jochen H M

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Retinoblastoma Binding Protein 4 Modulates Temozolomide Sensitivity in Glioblastoma by Regulating DNA Repair Proteins von Kitange, Gaspar J., Mladek, Ann C., Schroeder, Mark A., Pokorny, Jenny C., Carlson, Brett L., Zhang, Yuji, Nair, Asha A., Lee, Jeong-Heon, Yan, Huihuang, Decker, Paul A., Zhang, Zhiguo, Sarkaria, Jann N.

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Inhibition of Histone Deacetylation Potentiates the Evolution of Acquired Temozolomide Resistance Linked to MGMT Upregulation in Glioblastoma Xenografts von KITANGE, Gaspar J, MLADEK, Ann C, URRUTIA, Raul A, SARKARIA, Jann N, CARLSON, Brett L, SCHROEDER, Mark A, POKORNY, Jenny L, LING CEN, DECKER, Paul A, WENTING WU, LOMBERK, Gwen A, GUPTA, Shiv K

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Melanoma cells repress Desmoglein 1 in keratinocytes to promote tumor cell migration von Burks, Hope E, Pokorny, Jenny L, Koetsier, Jennifer L, Roth-Carter, Quinn R, Arnette, Christopher R, Gerami, Pedram, Seykora, John T, Johnson, Jodi L, Ren, Ziyou, Green, Kathleen J

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Efflux transporters at the blood-brain barrier limit delivery and efficacy of cyclin-dependent kinase 4/6 inhibitor palbociclib (PD-0332991) in an orthotopic brain tumor model von Parrish, Karen E, Pokorny, Jenny, Mittapalli, Rajendar K, Bakken, Katrina, Sarkaria, Jann N, Elmquist, William F

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Delineation of MGMT Hypermethylation as a Biomarker for Veliparib-Mediated Temozolomide-Sensitizing Therapy of Glioblastoma von Gupta, Shiv K, Kizilbash, Sani H, Carlson, Brett L, Mladek, Ann C, Boakye-Agyeman, Felix, Bakken, Katrina K, Pokorny, Jenny L, Schroeder, Mark A, Decker, Paul A, Cen, Ling, Eckel-Passow, Jeanette E, Sarkar, Gobinda, Ballman, Karla V, Reid, Joel M, Jenkins, Robert B, Verhaak, Roeland G, Sulman, Erik P, Kitange, Gaspar J, Sarkaria, Jann N

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The Efficacy of the Wee1 Inhibitor MK-1775 Combined with Temozolomide Is Limited by Heterogeneous Distribution across the Blood-Brain Barrier in Glioblastoma von Pokorny, Jenny L, Calligaris, David, Gupta, Shiv K, Iyekegbe, Jr, Dennis O, Mueller, Dustin, Bakken, Katrina K, Carlson, Brett L, Schroeder, Mark A, Evans, Debra L, Lou, Zhenkun, Decker, Paul A, Eckel-Passow, Jeanette E, Pucci, Vincenzo, Ma, Bennett, Shumway, Stuart D, Elmquist, William F, Agar, Nathalie Y R, Sarkaria, Jann N

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Active efflux of Dasatinib from the brain limits efficacy against murine glioblastoma: broad implications for the clinical use of molecularly targeted agents von Agarwal, Sagar, Mittapalli, Rajendar K, Zellmer, David M, Gallardo, Jose L, Donelson, Randy, Seiler, Charlie, Decker, Stacy A, Santacruz, Karen S, Pokorny, Jenny L, Sarkaria, Jann N, Elmquist, William F, Ohlfest, John R

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The role of LAT1 in (18)F-DOPA uptake in malignant gliomas von Youland, Ryan S, Kitange, Gaspar J, Peterson, Timothy E, Pafundi, Deanna H, Ramiscal, Judi A, Pokorny, Jenny L, Giannini, Caterina, Laack, Nadia N, Parney, Ian F, Lowe, Val J, Brinkmann, Debra H, Sarkaria, Jann N

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Docetaxel targets aggressive methylation profiles and serves as a radiosensitizer in high-risk meningiomas von Youngblood, Mark W, Tran, Anh N, Wang, Wenxia, An, Shejuan, Scholtens, Denise, Zhang, Lyndsee, O’Shea, Kaitlyn, Pokorny, Jenny L, Magill, Stephen T, Sachdev, Sean, Lukas, Rimas V, Ahmed, Atique, Unruh, Dusten, Walshon, Jordain, McCortney, Kathleen, Wang, Yufen, Baran, Aneta, Sahm, Felix, Aldape, Kenneth, Chandler, James P, David James, C, Heimberger, Amy B, Horbinski, Craig

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Preclinical modeling in glioblastoma patient-derived xenograft (GBM PDX) xenografts to guide clinical development of lisavanbulin—a novel tumor checkpoint controller targeting micr... von Burgenske, Danielle M, Talele, Surabhi, Pokorny, Jenny L, Mladek, Ann C, Bakken, Katrina K, Carlson, Brett L, Schroeder, Mark A, He, Lihong, Hu, Zeng, Gampa, Gautham, Kosel, Matthew L, Decker, Paul A, Kitange, Gaspar J, Schmitt-Hoffmann, Anne, Bachmann, Felix, Vaubel, Rachael A, Eckel-Passow, Jeanette E, Giannini, Caterina, McSheehy, Paul, Lane, Heidi A, Elmquist, William F, Sarkaria, Jann N

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Establishment, Maintenance, and In Vitro and In Vivo Applications of Primary Human Glioblastoma Multiforme (GBM) Xenograft Models for Translational Biology Studies and Drug Discove... von Carlson, Brett L., Pokorny, Jenny L., Schroeder, Mark A., Sarkaria, Jann N.

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Network Modeling Identifies Patient-specific Pathways in Glioblastoma von Tuncbag, Nurcan, Milani, Pamela, Pokorny, Jenny L., Johnson, Hannah, Sio, Terence T., Dalin, Simona, Iyekegbe, Dennis O., White, Forest M., Sarkaria, Jann N., Fraenkel, Ernest

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Anti-GD2-ch14.18/CHO coated nanoparticles mediate glioblastoma (GBM)-specific delivery of the aromatase inhibitor, Letrozole, reducing proliferation, migration and chemoresistance... von Tivnan, Amanda, Heilinger, Tatjana, Ramsey, Joanne M, O'Connor, Gemma, Pokorny, Jenny L, Sarkaria, Jann N, Stringer, Brett W, Day, Bryan W, Boyd, Andrew W, Kim, Ella L, Lode, Holger N, Cryan, Sally-Ann, Prehn, Jochen H M

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Targeting the PI3K Pathway in the Brain-Efficacy of a PI3K Inhibitor Optimized to Cross the Blood―Brain Barrier von SALPHATI, Laurent, HEFFRON, Timothy P, KOEPPEN, Hartmut, LAU, Shari, LEE, Leslie B, PANG, Jodie, PLISE, Emile G, POKORNY, Jenny L, BOU RESLAN, Hani, SARKARIA, Jann N, WALLIN, Jeffrey J, XIAOLIN ZHANG, ALICKE, Bruno, GOULD, Stephen E, OLIVERO, Alan G, PHILLIPS, Heidi S, NISHIMURA, Merry, BARCK, Kai, CARANO, Richard A, CHEONG, Jonathan, EDGAR, Kyle A, GREVE, Joan, KHARBANDA, Samir

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Decreased affinity for efflux transporters increases brain penetrance and molecular targeting of a PI3K/mTOR inhibitor in a mouse model of glioblastoma von Becker, Chani M, Oberoi, Rajneet K, McFarren, Stephan J, Muldoon, Daniel M, Pafundi, Deanna H, Pokorny, Jenny L, Brinkmann, Debra H, Ohlfest, John R, Sarkaria, Jann N, Largaespada, David A, Elmquist, William F

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Abstract 4781: The novel tubulin-binding ‘tumor checkpoint controller’ BAL101553 has anti-cancer activity alone and in combination treatments across a panel of GBM patient-derived... von Mladek, Ann C., Pokorny, Jenny L., Lane, Heidi, Bachmann, Felix, Schroeder, Mark A., Bakken, Katrina K., Carlson, Brett L., Decker, Paul A., Eckel-Passow, Jeanette E., Sarkaria, Jann N.

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Dangerous liaisons: Loss of keratinocyte control over melanocytes in melanomagenesis von Green, Kathleen J., Pokorny, Jenny, Jarrell, Brieanna

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