Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks von Schneider, William M., Luna, Joseph M., Hoffmann, H.-Heinrich, Sánchez-Rivera, Francisco J., Leal, Andrew A., Ashbrook, Alison W., Le Pen, Jérémie, Ricardo-Lax, Inna, Michailidis, Eleftherios, Peace, Avery, Stenzel, Ansgar F., Lowe, Scott W., MacDonald, Margaret R., Rice, Charles M., Poirier, John T.

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A combinatorial strategy for treating KRAS-mutant lung cancer von Manchado, Eusebio, Weissmueller, Susann, Morris, John P., Chen, Chi-Chao, Wullenkord, Ramona, Lujambio, Amaia, de Stanchina, Elisa, Poirier, John T., Gainor, Justin F., Corcoran, Ryan B., Engelman, Jeffrey A., Rudin, Charles M., Rosen, Neal, Lowe, Scott W.

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NK cell-mediated cytotoxicity contributes to tumor control by a cytostatic drug combination von Ruscetti, Marcus, Leibold, Josef, Bott, Matthew J, Fennell, Myles, Kulick, Amanda, Salgado, Nelson R, Chen, Chi-Chao, Ho, Yu-Jui, Sanchez-Rivera, Francisco J, Feucht, Judith, Baslan, Timour, Tian, Sha, Chen, Hsuan-An, Romesser, Paul B, Poirier, John T, Rudin, Charles M, de Stanchina, Elisa, Manchado, Eusebio, Sherr, Charles J, Lowe, Scott W

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Signatures of plasticity, metastasis, and immunosuppression in an atlas of human small cell lung cancer von Chan, Joseph M., Quintanal-Villalonga, Álvaro, Gao, Vianne Ran, Xie, Yubin, Allaj, Viola, Chaudhary, Ojasvi, Masilionis, Ignas, Egger, Jacklynn, Chow, Andrew, Walle, Thomas, Mattar, Marissa, Yarlagadda, Dig V.K., Wang, James L., Uddin, Fathema, Offin, Michael, Ciampricotti, Metamia, Qeriqi, Besnik, Bahr, Amber, de Stanchina, Elisa, Bhanot, Umesh K., Lai, W. Victoria, Bott, Matthew J., Jones, David R., Ruiz, Arvin, Baine, Marina K., Li, Yanyun, Rekhtman, Natasha, Poirier, John T., Nawy, Tal, Sen, Triparna, Mazutis, Linas, Hollmann, Travis J., Pe'er, Dana, Rudin, Charles M.

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Next-Generation Sequencing of Pulmonary Large Cell Neuroendocrine Carcinoma Reveals Small Cell Carcinoma-like and Non-Small Cell Carcinoma-like Subsets von Rekhtman, Natasha, Pietanza, Maria C, Hellmann, Matthew D, Naidoo, Jarushka, Arora, Arshi, Won, Helen, Halpenny, Darragh F, Wang, Hangjun, Tian, Shaozhou K, Litvak, Anya M, Paik, Paul K, Drilon, Alexander E, Socci, Nicholas, Poirier, John T, Shen, Ronglai, Berger, Michael F, Moreira, Andre L, Travis, William D, Rudin, Charles M, Ladanyi, Marc

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Targeting NOTCH activation in small cell lung cancer through LSD1 inhibition von Augert, Arnaud, Eastwood, Emily, Ibrahim, Ali H, Wu, Nan, Grunblatt, Eli, Basom, Ryan, Liggitt, Denny, Eaton, Keith D, Martins, Renato, Poirier, John T, Rudin, Charles M, Milletti, Francesca, Cheng, Wei-Yi, Mack, Fiona, MacPherson, David

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DNA methylation in small cell lung cancer defines distinct disease subtypes and correlates with high expression of EZH2 von Poirier, J T, Gardner, E E, Connis, N, Moreira, A L, de Stanchina, E, Hann, C L, Rudin, C M

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Design, execution, and analysis of pooled in vitro CRISPR/Cas9 screens von Miles, Linde A., Garippa, Ralph J., Poirier, John T.

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Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors von Hoffmann, H.-Heinrich, Sánchez-Rivera, Francisco J., Schneider, William M., Luna, Joseph M., Soto-Feliciano, Yadira M., Ashbrook, Alison W., Le Pen, Jérémie, Leal, Andrew A., Ricardo-Lax, Inna, Michailidis, Eleftherios, Hao, Yuan, Stenzel, Ansgar F., Peace, Avery, Zuber, Johannes, Allis, C. David, Lowe, Scott W., MacDonald, Margaret R., Poirier, John T., Rice, Charles M.

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Concurrent Mutations in STK11 and KEAP1 Promote Ferroptosis Protection and SCD1 Dependence in Lung Cancer von Wohlhieter, Corrin A., Richards, Allison L., Uddin, Fathema, Hulton, Christopher H., Quintanal-Villalonga, Àlvaro, Martin, Axel, de Stanchina, Elisa, Bhanot, Umeshkumar, Asher, Marina, Shah, Nisargbhai S., Hayatt, Omar, Buonocore, Darren J., Rekhtman, Natasha, Shen, Ronglai, Arbour, Kathryn C., Donoghue, Mark, Poirier, John T., Sen, Triparna, Rudin, Charles M.

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Generation of hepatoma cell lines deficient in microsomal triglyceride transfer protein von Anaganti, Narasimha, Chattopadhyay, Atrayee, Poirier, John T., Hussain, M. Mahmood

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Selective Tropism of Seneca Valley Virus for Variant Subtype Small Cell Lung Cancer von POIRIER, J. T, DOBROMILSKAYA, Irina, MORIARTY, Whei F, PEACOCK, Craig D, HANN, Christine L, RUDIN, Charles M

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CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer von Weiskopf, Kipp, Jahchan, Nadine S, Schnorr, Peter J, Cristea, Sandra, Ring, Aaron M, Maute, Roy L, Volkmer, Anne K, Volkmer, Jens-Peter, Liu, Jie, Lim, Jing Shan, Yang, Dian, Seitz, Garrett, Nguyen, Thuyen, Wu, Di, Jude, Kevin, Guerston, Heather, Barkal, Amira, Trapani, Francesca, George, Julie, Poirier, John T, Gardner, Eric E, Miles, Linde A, de Stanchina, Elisa, Lofgren, Shane M, Vogel, Hannes, Winslow, Monte M, Dive, Caroline, Thomas, Roman K, Rudin, Charles M, van de Rijn, Matt, Majeti, Ravindra, Garcia, K Christopher, Weissman, Irving L, Sage, Julien

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Quantitation of Murine Stroma and Selective Purification of the Human Tumor Component of Patient-Derived Xenografts for Genomic Analysis von Schneeberger, Valentina E, Allaj, Viola, Gardner, Eric E, Poirier, J T, Rudin, Charles M

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ONECUT2 is a driver of neuroendocrine prostate cancer von Guo, Haiyang, Ci, Xinpei, Ahmed, Musaddeque, Hua, Junjie Tony, Soares, Fraser, Lin, Dong, Puca, Loredana, Vosoughi, Aram, Xue, Hui, Li, Estelle, Su, Peiran, Chen, Sujun, Nguyen, Tran, Liang, Yi, Zhang, Yuzhe, Xu, Xin, Xu, Jing, Sheahan, Anjali V., Ba-Alawi, Wail, Zhang, Si, Mahamud, Osman, Vellanki, Ravi N., Gleave, Martin, Bristow, Robert G., Haibe-Kains, Benjamin, Poirier, John T., Rudin, Charles M., Tsao, Ming-Sound, Wouters, Bradly G., Fazli, Ladan, Feng, Felix Y., Ellis, Leigh, van der Kwast, Theo, Berlin, Alejandro, Koritzinsky, Marianne, Boutros, Paul C., Zoubeidi, Amina, Beltran, Himisha, Wang, Yuzhuo, He, Housheng Hansen

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Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer von Rudin, Charles M, Durinck, Steffen, Stawiski, Eric W, Poirier, John T, Modrusan, Zora, Shames, David S, Bergbower, Emily A, Guan, Yinghui, Shin, James, Guillory, Joseph, Rivers, Celina Sanchez, Foo, Catherine K, Bhatt, Deepali, Stinson, Jeremy, Gnad, Florian, Haverty, Peter M, Gentleman, Robert, Chaudhuri, Subhra, Janakiraman, Vasantharajan, Jaiswal, Bijay S, Parikh, Chaitali, Yuan, Wenlin, Zhang, Zemin, Koeppen, Hartmut, Wu, Thomas D, Stern, Howard M, Yauch, Robert L, Huffman, Kenneth E, Paskulin, Diego D, Illei, Peter B, Varella-Garcia, Marileila, Gazdar, Adi F, de Sauvage, Frederic J, Bourgon, Richard, Minna, John D, Brock, Malcolm V, Seshagiri, Somasekar

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Multiomic Analysis of Lung Tumors Defines Pathways Activated in Neuroendocrine Transformation von Quintanal-Villalonga, Alvaro, Taniguchi, Hirokazu, Zhan, Yingqian A., Hasan, Maysun M., Chavan, Shweta S., Meng, Fanli, Uddin, Fathema, Manoj, Parvathy, Donoghue, Mark T. A., Won, Helen H., Chan, Joseph M., Ciampricotti, Metamia, Chow, Andrew, Offin, Michael, Chang, Jason C., Ray-Kirton, Jordana, Tischfield, Sam E., Egger, Jacklynn, Bhanot, Umesh K., Linkov, Irina, Asher, Marina, Sinha, Sonali, Silber, Joachim, Iacobuzio-Donahue, Christine A., Roehrl, Michael H., Hollmann, Travis J., Yu, Helena A., Qiu, Juan, de Stanchina, Elisa, Baine, Marina K., Rekhtman, Natasha, Poirier, John T., Loomis, Brian, Koche, Richard P., Rudin, Charles M., Sen, Triparna

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New Approaches to SCLC Therapy: From the Laboratory to the Clinic von Poirier, John T., George, Julie, Owonikoko, Taofeek K., Berns, Anton, Brambilla, Elisabeth, Byers, Lauren A., Carbone, David, Chen, Huanhuan J., Christensen, Camilla L., Dive, Caroline, Farago, Anna F., Govindan, Ramaswamy, Hann, Christine, Hellmann, Matthew D., Horn, Leora, Johnson, Jane E., Ju, Young S., Kang, Sumin, Krasnow, Mark, Lee, James, Lee, Se-Hoon, Lehman, Jonathan, Lok, Benjamin, Lovly, Christine, MacPherson, David, McFadden, David, Minna, John, Oser, Matthew, Park, Keunchil, Park, Kwon-Sik, Pommier, Yves, Quaranta, Vito, Ready, Neal, Sage, Julien, Scagliotti, Giorgio, Sos, Martin L., Sutherland, Kate D., Travis, William D., Vakoc, Christopher R., Wait, Sarah J., Wistuba, Ignacio, Wong, Kwok Kin, Zhang, Hua, Daigneault, Jillian, Wiens, Jacinta, Rudin, Charles M., Oliver, Trudy G.

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Replication and single-cycle delivery of SARS-CoV-2 replicons von Ricardo-Lax, Inna, Luna, Joseph M., Thao, Tran Thi Nhu, Le Pen, Jeremie, Yu, Yingpu, Hoffmann, H-Heinrich, Schneider, William M., Razooky, Brandon S., Fernandez-Martinez, Javier, Schmidt, Fabian, Weisblum, Yiska, Trueb, Bettina Salome, Veiga, Ines Berenguer, Schmied, Kimberly, Ebert, Nadine, Michailidis, Eleftherios, Peace, Avery, Sanchez-Rivera, Francisco J., Lowe, Scott W., Rout, Michael P., Hatziioannou, Theodora, Bieniasz, Paul D., Poirier, John T., MacDonald, Margaret R., Thiel, Volker, Rice, Charles M.

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Target engagement imaging of PARP inhibitors in small-cell lung cancer von Carney, Brandon, Kossatz, Susanne, Lok, Benjamin H., Schneeberger, Valentina, Gangangari, Kishore K., Pillarsetty, Naga Vara Kishore, Weber, Wolfgang A., Rudin, Charles M., Poirier, John T., Reiner, Thomas

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