Targeting Macrophages in Cancer: From Bench to Bedside von Poh, Ashleigh R, Ernst, Matthias

Volltext

Tumor-Associated Macrophages in Pancreatic Ductal Adenocarcinoma: Therapeutic Opportunities and Clinical Challenges von Poh, Ashleigh R., Ernst, Matthias

Volltext

Swinging between shine and shadow: Theoretical advances on thermally activated vibropolaritonic chemistry von Campos-Gonzalez-Angulo, J. A., Poh, Y. R., Du, M., Yuen-Zhou, J.

Volltext

IL-33-mediated mast cell activation promotes gastric cancer through macrophage mobilization von Eissmann, Moritz F., Dijkstra, Christine, Jarnicki, Andrew, Phesse, Toby, Brunnberg, Jamina, Poh, Ashleigh R., Etemadi, Nima, Tsantikos, Evelyn, Thiem, Stefan, Huntington, Nicholas D., Hibbs, Margaret L., Boussioutas, Alex, Grimbaldeston, Michele A., Buchert, Michael, O’Donoghue, Robert J. J., Masson, Frederick, Ernst, Matthias

Volltext

Multicellular Effects of STAT3 in Non-small Cell Lung Cancer: Mechanistic Insights and Therapeutic Opportunities von Parakh, Sagun, Ernst, Matthias, Poh, Ashleigh R

Volltext

RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis von Rickard, James A., O’Donnell, Joanne A., Evans, Joseph M., Lalaoui, Najoua, Poh, Ashleigh R., Rogers, TeWhiti, Vince, James E., Lawlor, Kate E., Ninnis, Robert L., Anderton, Holly, Hall, Cathrine, Spall, Sukhdeep K., Phesse, Toby J., Abud, Helen E., Cengia, Louise H., Corbin, Jason, Mifsud, Sandra, Di Rago, Ladina, Metcalf, Donald, Ernst, Matthias, Dewson, Grant, Roberts, Andrew W., Alexander, Warren S., Murphy, James M., Ekert, Paul G., Masters, Seth L., Vaux, David L., Croker, Ben A., Gerlic, Motti, Silke, John

Volltext

Hematopoietic cell kinase (HCK) as a therapeutic target in immune and cancer cells von Poh, Ashleigh R, O'Donoghue, Robert J J, Ernst, Matthias

Volltext

An intrasplenic injection model of pancreatic cancer metastasis to the liver in mice von O’Brien, Megan, Ernst, Matthias, Poh, Ashleigh R.

Volltext

A tuft cell - ILC2 signaling circuit provides therapeutic targets to inhibit gastric metaplasia and tumor development von O’Keefe, Ryan N., Carli, Annalisa L. E., Baloyan, David, Chisanga, David, Shi, Wei, Afshar-Sterle, Shoukat, Eissmann, Moritz F., Poh, Ashleigh R., Pal, Bhupinder, Seillet, Cyril, Locksley, Richard M., Ernst, Matthias, Buchert, Michael

Volltext

Mouse models for gastric cancer: Matching models to biological questions von Poh, Ashleigh R, O'Donoghue, Robert J J, Ernst, Matthias, Putoczki, Tracy L

Volltext

Functional roles of SRC signaling in pancreatic cancer: Recent insights provide novel therapeutic opportunities von Poh, Ashleigh R., Ernst, Matthias

Volltext

Editorial: Overcoming drug relapse and therapy resistance in NSCLC von Parakh, Sagun, Leong, Tracy L, Best, Sarah A, Poh, Ashleigh R

Volltext

Longitudinal quantification of mouse gastric tumor organoid viability and growth using luminescence and microscopy von Morrow, Riley J., Ernst, Matthias, Poh, Ashleigh R.

Volltext

Mutant TP53 switches therapeutic vulnerability during gastric cancer progression within interleukin-6 family cytokines von Huber, Anne, Allam, Amr H., Dijkstra, Christine, Thiem, Stefan, Huynh, Jennifer, Poh, Ashleigh R., Konecnik, Joshua, Jacob, Saumya P., Busuttil, Rita, Liao, Yang, Chisanga, David, Shi, Wei, Alorro, Mariah G., Forrow, Stephen, Tauriello, Daniele V.F., Batlle, Eduard, Boussioutas, Alex, Williams, David S., Buchert, Michael, Ernst, Matthias, Eissmann, Moritz F.

Volltext

Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal cancer growth von Thilakasiri, Pathum, Huynh, Jennifer, Poh, Ashleigh R, Tan, Chin Wee, Nero, Tracy L, Tran, Kelly, Parslow, Adam C, Afshar‐Sterle, Shoukat, Baloyan, David, Hannan, Natalie J, Buchert, Michael, Scott, Andrew Mark, Griffin, Michael DW, Hollande, Frederic, Parker, Michael W, Putoczki, Tracy L, Ernst, Matthias, Chand, Ashwini L

Volltext

Combination of bazedoxifene with chemotherapy and SMAC-mimetics for the treatment of colorectal cancer von Dmello, Rhynelle S., Palmieri, Michelle, Thilakasiri, Pathum S., Doughty, Larissa, Nero, Tracy L., Poh, Ashleigh R., To, Sarah Q., Lee, Erinna F., Douglas Fairlie, W., Mielke, Lisa, Parker, Michael W., Poon, Ivan K. H., Batlle, Eduard, Ernst, Matthias, Chand, Ashwini L.

Volltext

Inhibition of the SRC Kinase HCK Impairs STAT3-Dependent Gastric Tumor Growth in Mice von Poh, Ashleigh R, Dwyer, Amy R, Eissmann, Moritz F, Chand, Ashwini L, Baloyan, David, Boon, Louis, Murrey, Michael W, Whitehead, Lachlan, O'Brien, Megan, Lowell, Clifford A, Putoczki, Tracy L, Pixley, Fiona J, O'Donoghue, Robert J J, Ernst, Matthias

Volltext

A novel BH3-mimetic, AZD0466, targeting BCL-XL and BCL-2 is effective in pre-clinical models of malignant pleural mesothelioma von Arulananda, Surein, O’Brien, Megan, Evangelista, Marco, Jenkins, Laura J., Poh, Ashleigh R., Walkiewicz, Marzena, Leong, Trishe, Mariadason, John M., Cebon, Jonathan, Balachander, Srividya B., Cidado, Justin R., Lee, Erinna F., John, Thomas, Fairlie, Walter D.

Volltext

Loss of Bcl-G, a Bcl-2 family member, augments the development of inflammation-associated colorectal cancer von Nguyen, Paul M., Dagley, Laura F., Preaudet, Adele, Lam, Nga, Giam, Maybelline, Fung, Ka Yee, Aizel, Kaheina, van Duijneveldt, Gemma, Tan, Chin Wee, Hirokawa, Yumiko, Yip, Hon Yan K., Love, Christopher G., Poh, Ashleigh R., Cruz, Akshay D’, Burstroem, Charlotte, Feltham, Rebecca, Abdirahman, Suad M., Meiselbach, Kristy, Low, Ronnie Ren Jie, Palmieri, Michelle, Ernst, Matthias, Webb, Andrew I., Burgess, Tony, Sieber, Oliver M., Bouillet, Philippe, Putoczki, Tracy L.

Volltext

Tumor macrophage functional heterogeneity can inform the development of novel cancer therapies von Nasir, Ibraheem, McGuinness, Conor, Poh, Ashleigh R, Ernst, Matthias, Darcy, Phillip K, Britt, Kara L

Volltext