Complex epigenetic regulation of Engrailed-2 (EN-2) homeobox gene in the autism cerebellum von James, S J, Shpyleva, Svitlana, Melnyk, Stepan, Pavliv, Oleksandra, Pogribny, I P

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Irradiation induces DNA damage and modulates epigenetic effectors in distant bystander tissue in vivo von Koturbash, I, Rugo, R E, Hendricks, C A, Loree, J, Thibault, B, Kutanzi, K, Pogribny, I, Yanch, J C, Engelward, B P, Kovalchuk, O

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Elevated 5-hydroxymethylcytosine in the Engrailed-2 (EN-2) promoter is associated with increased gene expression and decreased MeCP2 binding in autism cerebellum von James, S J, Shpyleva, S, Melnyk, S, Pavliv, O, Pogribny, I P

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Epigenetic events in tumorigenesis: putting the pieces together von Pogribny, I P

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Intracellular S-Adenosylhomocysteine Concentrations Predict Global DNA Hypomethylation in Tissues of Methyl-Deficient Cystathionine β-Synthase Heterozygous Mice von Caudill, Marie A., Wang, Jennie C., Melnyk, Stepan, Pogribny, Igor P., Collins, Michael D., Santos-Guzman, Jesus, Swendseid, Marian E., Cogger, Edward A., James, S. Jill, Jernigan, Stefanie

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Abnormal folate metabolism and mutation in the methylenetetrahydrofolate reductase gene may be maternal risk factors for Down syndrome von JAMES, S. J, POGRIBNA, M, GAYLOR, D. W, POGRIBNY, I. P, MELNYK, S, HINE, R. J, GIBSON, J. B, PING YI, TAFOYA, D. L, SWENSON, D. H, WILSON, V. L

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Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women von Jacob, R.A, Gretz, D.M, Taylor, P.C, James, S.J, Pogribny, I.P, Miller, B.J, Henning, S.M, Swendseid, M.E

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Measurement of Plasma and Intracellular S-Adenosylmethionine and S-Adenosylhomocysteine Utilizing Coulometric Electrochemical Detection: Alterations with Plasma Homocysteine and Py... von Melnyk, Stepan, Pogribna, Marta, Pogribny, Igor P, Yi, Ping, James, S. Jill

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Increase in Plasma Homocysteine Associated with Parallel Increases in Plasma S-Adenosylhomocysteine and Lymphocyte DNA Hypomethylation von Yi, Ping, Melnyk, Stepan, Pogribna, Marta, Pogribny, Igor P., Hine, R. Jean, James, S. Jill

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Epigenetic changes in the rat livers induced by pyrazinamide treatment von Kovalenko, V.M., Bagnyukova, T.V., Sergienko, O.V., Bondarenko, L.B., Shayakhmetova, G.M., Matvienko, A.V., Pogribny, I.P.

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Reduction of p53 gene expression in human primary hepatocellular carcinoma is associated with promoter region methylation without coding region mutation von Pogribny, I.P., James, S.Jill

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Folate deficiency in rats induces DNA strand breaks and hypomethylation within the p53 tumor suppressor gene von Kim, YI, Pogribny, IP, Basnakian, AG, Miller, JW, Selhub, J, James, SJ, Mason, JB

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Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition von ZHOUTAO CHEN, KARAPLIS, Andrew C, BOTTIGLIERI, Teodoro, BAGLEY, Pamela, SELHUB, Jacob, RUDNICKI, Michael A, JAMES, S. Jill, ROZEN, Rima, ACKERMAN, Susan L, POGRIBNY, Igor P, MELNYK, Stepan, LUSSIER-CACAN, Suzanne, MOY FONG CHEN, PAI, Aditya, JOHN, Simon W. M, SMITH, Richard S

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Single-site methylation within the p53 promoter region reduces gene expression in a reporter gene construct : Possible in vivo relevance during tumorigenesis von POGRIBNY, I. P, POGRIBNA, M, CHRISTMAN, J. K, JAMES, S. J

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S-Adenosylhomocysteine Hydrolase Deficiency in a Human: A Genetic Disorder of Methionine Metabolism von Barić, Ivo, Fumić, Ksenija, Glenn, Byron, Ćuk, Mario, Schulze, Andreas, Finkelstein, James D., James, S. Jill, Mejas̆ki-Bos̆njak, Vlatka, Paz̆anin, Leo, Pogribny, Igor P., Rados̆, Marko, Sarnavka, Vladimir, Sćukanec-Spoljar, Mira, Allen, Robert H., Stabler, Sally, Uzelac, Lidija, Vugrek, Oliver, Wagner, Conrad, Zeisel, Steven, Mudd, S. Harvey, Cantoni, Giulio L.

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Uracil misincorporation, DNA strand breaks, and gene amplification are associated with tumorigenic cell transformation in folate deficient/repleted Chinese hamster ovary cells von Melnyk, S, Pogribna, M, Miller, B.J, Basnakian, A.G, Pogribny, I.P, James, S.J

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Breaks in genomic DNA and within the p53 gene are associated with hypomethylation in livers of folate/methyl-deficient rats von POGRIBNY, I. P, BASNAKIAN, A. G, MILLER, B. J, LOPATINA, N. G, POIRIER, L. A, JAMES, S. J

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Alterations in hepatic p53 gene methylation patterns during tumor progression with folate/methyl deficiency in the rat von Pogribny, Igor P., Miller, Barbara J., James, S.Jill

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S‐Adenosylhomocysteine hydrolase deficiency: A second patient, the younger brother of the index patient, and outcomes during therapy von Barić, I., Ćuk, M., Fumić, K., Vugrek, O., Allen, R. H., Glenn, B., Maradin, M., Pažanin, L., Pogribny, I., Radoš, M., Sarnavka, V., Schulze, A., Stabler, S., Wagner, C., Zeisel, S. H., Mudd, S. H.

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S‐Adenosylhomocysteine hydrolase deficiency in a 26‐year‐old man von Buist, N. R. M., Glenn, B., Vugrek, O., Wagner, C., Stabler, S., Allen, R. H., Pogribny, I., Schulze, A., Zeisel, S. H., Barić, I., Mudd, S. H.

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