Induction of hemangiosarcoma in mice after chronic treatment with S1P-modulator siponimod and its lack of relevance to rat and human von Pognan, F.

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Genomics and proteomics analysis of acetaminophen toxicity in mouse liver von RUEPP, Stefan U, TONGE, Robert P, SHAW, Joanne, WALLIS, Nicola, POGNAN, Francois

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Validation of an in vitro screen for phospholipidosis using a high-content biology platform von Morelli, J K, Buehrle, M, Pognan, F, Barone, L R, Fieles, W, Ciaccio, P J

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1106 TELBIVUDINE DOES NOT CAUSE MITOCHONDRIAL TOXICITY IN HUMAN SKELETAL MUSCLE CELLS AND NEURONAL CELLS von Dong, M, Persohn, E, Grenet, O, Chibout, S.-D, Pognan, F, Wolf, A, Weaver, M, Li, L

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eTRANSAFE's Rosetta stone - a new approach to overcome safety translational hurdles von Kors, J, van Mulligen, E, van der Lei, J, Pognan, F, Steger-Hartmann, T.

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Modulation of Notch Processing by γ-Secretase Inhibitors Causes Intestinal Goblet Cell Metaplasia and Induction of Genes Known to Specify Gut Secretory Lineage Differentiation von Milano, Joseph, McKay, Jenny, Dagenais, Claude, Foster-Brown, Linda, Pognan, Francois, Gadient, Reto, Jacobs, Robert T., Zacco, Anna, Greenberg, Barry, Ciaccio, Paul J.

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Validation and development of fluorescence two-dimensional differential gel electrophoresis proteomics technology von Tonge, Robert, Shaw, Joanne, Middleton, Brian, Rowlinson, Rachel, Rayner, Steve, Young, Janice, Pognan, Francois, Hawkins, Edward, Currie, Ian, Davison, Matthew

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In utero transmission of Encephalitozoon cuniculi strain type I in rabbits von Baneux, P J R, Pognan, F

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Human iPSC-derived retinal organoid model for in vitro toxicity screening von Chichagova, V., Dorgau, B., de Santis, C., Georgiou, M., Carter, M, Hilgen, G., Collin, J., Queen, R., Chung, G., Ajeian, J., Moya-Molina, M, Kustermann, S., Pognan, F., Hewitt, P., Schmitt, M, Sernagor, E., Armstrong, L., Lako, M.

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Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity von O'Brien, John, Wilson, Ian, Orton, Terry, Pognan, François

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An Integrated Metabonomic Investigation of Acetaminophen Toxicity in the Mouse Using NMR Spectroscopy von Coen, Muireann, Lenz, Eva M, Nicholson, Jeremy K, Wilson, Ian D, Pognan, Francois, Lindon, John C

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Integrated application of transcriptomics and metabonomics yields new insight into the toxicity due to paracetamol in the mouse von Coen, Muireann, Ruepp, Stefan U., Lindon, John C., Nicholson, Jeremy K., Pognan, François, Lenz, Eva M., Wilson, Ian D.

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Arctigenin's mode of toxicity in oxidative metabolizing cell lines von Riebel, Virginie, Brecht, K., Bonifacio, A., Marcellin, M., Couttet, P., Chibout, S.D., Pognan, F., Wolf, A., Uteng, M.

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Pharmacodynamic profiling of EGFR inhibitors in human keratinocytes von Balavenkatraman, K.K., Vicart, A., Couttet, P., Ledieu, D., Hopfer, U., Rathfelder, N., Bertschi, B., Greutmann, B., Marcellin, M., Chibout, S.D., Lambert, A., Moggs, J., Pognan, F., Wolf, A.

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Synthesis and Structure-Activity Relationship of Methyl-Substituted Indolo[2,3-b]quinolines: Novel Cytotoxic, DNA Topoisomerase II Inhibitors von Peczynska-Czoch, Wanda, Pognan, Francois, Kaczmarek, Lukasz, Boratynski, Janusz

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In silico prediction of in vivo toxicity - the first steps of the e-Tox consortium von Steger-Hartmann, T., Pognan, F., Sanz, F., Diaz, C., Sutter, A., Pastor, M.

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Establishment of a rat Sertoli cell line that displays the morphological and some of the functional characteristics of the native cell von POGNAN, F, MASSON, M.-T, LAGELLE, F, CHARUEL, C

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In silico prediction of in vivo toxicities (eTox)—The Innovative Medicines Initiative Approach von Steger-Hartmann, Thomas, Pognan, Francois, Sanz, Ferran, Diaz, Carlos Acedo

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Does cruciform DNA provide a recognition signal for DNA-topoisomerase II? von Pognan, F., Paoletti, C.

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Genome-wide analysis of DNA methylation profiles in a preclinical animal model of non-genotoxic carcinogenesis von Moggs, Jonathan, Teo, Soon Siong, Mueller, Arne, Morawiec, Laurent, Roloff, Tim, Heard, David, Staedtler, Frank, Schubeler, Dirk, Mohn, Fabian, Goodman, Jay, Phillips, Jennifer, Zamurovic, Natasa, Pognan, Francois, Chibout, Salah-Dine, Moulin, Pierre, Couttet, Philippe, Marlowe, Jennifer, Grenet, Olivier

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