[18F]CFA as a clinically translatable probe for PET imaging of deoxycytidine kinase activity von Kim, Woosuk, Le, Thuc M., Wei, Liu, Poddar, Soumya, Bazzy, Jimmy, Wang, Xuemeng, Uong, Nhu T., Abt, Evan R., Capri, Joseph R., Austin, Wayne R., Van Valkenburgh, Juno S., Steele, Dalton, Gipson, Raymond M., Slavik, Roger, Cabebe, Anthony E., Taechariyakul, Thotsophon, Yaghoubi, Shahriar S., Lee, Jason T., Sadeghi, Saman, Lavie, Arnon, Faull, Kym F., Witte, Owen N., Donahue, Timothy R., Phelps, Michael E., Herschman, Harvey R., Herrmann, Ken, Czernin, Johannes, Radu, Caius G.

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ATR inhibition facilitates targeting of leukemia dependence on convergent nucleotide biosynthetic pathways von Le, Thuc M., Poddar, Soumya, Capri, Joseph R., Abt, Evan R., Kim, Woosuk, Wei, Liu, Uong, Nhu T., Cheng, Chloe M., Braas, Daniel, Nikanjam, Mina, Rix, Peter, Merkurjev, Daria, Zaretsky, Jesse, Kornblum, Harley I., Ribas, Antoni, Herschman, Harvey R., Whitelegge, Julian, Faull, Kym F., Donahue, Timothy R., Czernin, Johannes, Radu, Caius G.

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Reexamination of magnetic isotope and field effects on adenosine triphosphate production by creatine kinase von Crotty, Darragh, Silkstone, Gary, Poddar, Soumya, Ranson, Richard, Prina-Mello, Adriele, Wilson, Michael T., Coey, J. M. D.

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CD19 target evasion as a mechanism of relapse in large B-cell lymphoma treated with axicabtagene ciloleucel von Plaks, Vicki, Rossi, John M., Chou, Justin, Wang, Linghua, Poddar, Soumya, Han, Guangchun, Wang, Zixing, Kuang, Shao-Qing, Chu, Fuliang, Davis, Richard E., Vega, Francisco, Bashir, Zahid, Jacobson, Caron A., Locke, Frederick L., Reagan, Patrick M., Rodig, Scott J., Lekakis, Lazaros J., Flinn, Ian W., Miklos, David B., Bot, Adrian, Neelapu, Sattva S.

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Abstract 3881: Relating tumor drug concentrations to target effect with semi physiologic PK-PD modeling in drug development: An application using a novel dCK inhibitor von Poddar, Soumya, Nikanjam, Mina, Capparelli, Edmund, Le, Thuc, Wei, Liu, Radu, Caius

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Establishing 177Lu-PSMA-617 Radioligand Therapy in a Syngeneic Model of Murine Prostate Cancer von Fendler, Wolfgang P, Stuparu, Andreea D, Evans-Axelsson, Susan, Lückerath, Katharina, Wei, Liu, Kim, Woosuk, Poddar, Soumya, Said, Jonathan, Radu, Caius G, Eiber, Matthias, Czernin, Johannes, Slavik, Roger, Herrmann, Ken

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ZUMA-19: A Phase 1/2 Study of Axicabtagene Ciloleucel Plus Lenzilumab in Patients With Relapsed or Refractory Large B-Cell Lymphoma von Oluwole, Olalekan O., Kenderian, Saad S., Shiraz, Parveen, Karmali, Reem, Reshef, Ran, McCarthy, Philip L., Ghosh, Nilanjan, Lazaryan, Aleksandr, Filosto, Simone, Poddar, Soumya, Mao, Daqin, Peng, Andrew, Kilcoyne, Adrian, Nahas, Myrna, Neelapu, Sattva S.

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Targeting CNS Lymphoma with Intravenous Axicabtagene Ciloleucel: Evidence for Transcriptional Evolution Towards a Prominent Interferon Signature in CAR-T Cells Trafficking to the T... von Gerdemann, Ulrike, Kaminski, James, Albanese, Alexandre, Keskula, Paula, Cagnin, Lorenzo, Betz, Kayla, Zavistaski, Jillian, Fleming, Ryan A, Falvey, Caroline, Bouvier, Riemke, Jones, Julia, Poddar, Soumya, Mattie, Mike, Chukwueke, Ugonma, Torres, Alexandra, Jacobson, Caron A., Nayak, Lakshmi, Kean, Leslie S.

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NAD⁺ depletion by type I interferon signaling sensitizes pancreatic cancer cells to NAMPT inhibition von Moore, Alexandra M., Zhou, Lei, Cui, Jing, Li, Luyi, Wu, Nanping, Yu, Alice, Poddar, Soumya, Liang, Keke, Abt, Evan R., Kim, Stephanie, Ghukasyan, Razmik, Khachatourian, Nooneh, Pagano, Kristina, Elliott, Irmina, Dann, Amanda M., Riahi, Rana, Le, Thuc, Dawson, David W., Radub, Caius G., Donahue, Timothy R.

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Axicabtagene Ciloleucel (Axi-Cel) in Patients with Relapsed/Refractory Indolent Non-Hodgkin Lymphoma: 4-Year Follow-up from the Phase 2 ZUMA-5 Trial von Neelapu, Sattva S., Chavez, Julio C., Sehgal, Alison R, Epperla, Narendranath, Ulrickson, Matthew L., Bachy, Emmanuel, Munshi, Pashna N., Casulo, Carla, Maloney, David G, de Vos, Sven, Reshef, Ran, Leslie, Lori A., Oluwole, Olalekan O., Yakoub-Agha, Ibrahim, Khanal, Rashmi, Rosenblatt, Joseph D., Peng, Weixin, Lui, Christine, Wulff, Jacob, Shen, Rhine R., Poddar, Soumya, Lee, Andrew, Miao, Harry, Nikolajeva, Olga, Jacobson, Caron A.

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Lysosome inhibition sensitizes pancreatic cancer to replication stress by aspartate depletion von Elliott, Irmina A., Dann, Amanda M., Xu, Shili, Kim, Stephanie S., Abt, Evan R., Kim, Woosuk, Poddar, Soumya, Moore, Alexandra, Zhou, Lei, Williams, Jennifer L., Capri, Joseph R., Ghukasyan, Razmik, Matsumura, Cynthia, Tucker, D. Andrew, Armstrong, Wesley R., Cabebe, Anthony E., Wu, Nanping, Li, Luyi, Le, Thuc M., Radu, Caius G., Donahue, Timothy R.

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Favorable tumor immune microenvironment (TME) and robust chimeric antigen receptor (CAR) T-cell expansion may overcome tumor burden (TB) and promote durable efficacy with axicabtag... von Chou, Justin, Plaks, Vicki, Poddar, Soumya, Wang, Zixing, Locke, Frederick Lundry, Neelapu, Sattva Swarup, Miklos, David Bernard, Jacobson, Caron A., Armand, Philippe, Bashir, Zahid, Galon, Jérôme, Rossi, John M., Bot, Adrian

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A Pilot Study of Axicabtagene Ciloleucel (axi-cel) for the Treatment of Relapsed/Refractory Primary and Secondary Central Nervous System Lymphoma (CNSL) von Jacobson, Caron A., Falvey, Caroline, Bouvier, Riemke, Hogan, Sarah, Kendricken, Elizabeth, Jones, Julia, Grimm, Elizabeth, Redd, Robert A., Lee, Eudocia Q, Gonzalez Castro, Luis, Chukwueke, Ugonma, McFaline Figueroa, Jose, Kim, Austin I., Torres, Alexandra, Ramsdell, Linda, Kean, Leslie S., Gerdemann, Ulrike, Albanese, Alexandre, Keskula, Paula, Meredith, David, Sholl, Lynette, Poddar, Soumya, Davis, Madison, Mao, Daquin, Filosto, Simone, Mattie, Mike, Armand, Philippe, Nayak, Lakshmi

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3-Year Follow-up Analysis of ZUMA-5: A Phase 2 Study of Axicabtagene Ciloleucel (Axi-Cel) in Patients with Relapsed/Refractory (R/R) Indolent Non-Hodgkin Lymphoma (iNHL) von Neelapu, Sattva S., Chavez, Julio, Sehgal, Alison R., Epperla, Narendranath, Ulrickson, Matthew, Bachy, Emanuel, Munshi, Pashna N., Casulo, Carla, Maloney, David G., de Vos, Sven, Reshef, Ran, Leslie, Lori A., Oluwole, Olalekan O., Yakoub-Agha, Ibrahim, Khanal, Rashmi, Rosenblatt, Joseph D., Yan, Jiali, Song, Qinghua, Peng, Weixin, Lui, Christine, Wulff, Jacob, Shen, Rhine R., Poddar, Soumya, Miao, Harry, Beygi, Sara, Jacobson, Caron A.

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Development and preclinical pharmacology of a novel dCK inhibitor, DI-87 von Poddar, Soumya, Capparelli, Edmund V., Rosser, Ethan W., Gipson, Raymond M., Wei, Liu, Le, Thuc, Jung, Michael E., Radu, Caius, Nikanjam, Mina

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Abstract 4064: Relating tumor drug concentrations to target effect with semi-physiologic PK-PD modeling in drug development: an application using a novel dCK inhibitor von Nikanjam, Mina, Poddar, Soumya, Capparelli, Edmund, Le, Thuc, Wei, Liu, Radu, Caius

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Abstract A41: Nucleotide metabolism heterogeneity in mutant KRAS pancreatic cancer von Le, Thuc M., Kim, Woosuk, Capri, Joseph R., Cabebe, Anthony E., Armstrong, Wes, Abt, Evan, Poddar, Soumya, Xu, Shili, Dawson, Dave, Donahue, Timothy R., Radu, Caius G.

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Activity and electrochemical properties: iron complexes of the anticancer drug triapine and its analogs von Plamthottam, Sheba, Sun, Daniel, Van Valkenburgh, Juno, Valenzuela, Jeffrey, Ruehle, Bastian, Steele, Dalton, Poddar, Soumya, Marshalik, Maxim, Hernandez, Selena, Radu, Caius Gabriel, Zink, Jeffrey I.

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Metabolic Modifier Screen Reveals Secondary Targets of Protein Kinase Inhibitors within Nucleotide Metabolism von Abt, Evan R., Rosser, Ethan W., Durst, Matthew A., Lok, Vincent, Poddar, Soumya, Le, Thuc M., Cho, Arthur, Kim, Woosuk, Wei, Liu, Song, Janet, Capri, Joseph R., Xu, Shili, Wu, Nanping, Slavik, Roger, Jung, Michael E., Damoiseaux, Robert, Czernin, Johannes, Donahue, Timothy R., Lavie, Arnon, Radu, Caius G.

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Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells von Abt, Evan R., Le, Thuc M., Dann, Amanda M., Capri, Joseph R., Poddar, Soumya, Lok, Vincent, Li, Luyi, Liang, Keke, Creech, Amanda L., Rashid, Khalid, Kim, Woosuk, Wu, Nanping, Cui, Jing, Cho, Arthur, Lee, Hailey Rose, Rosser, Ethan W., Link, Jason M., Czernin, Johannes, Wu, Ting-Ting, Damoiseaux, Robert, Dawson, David W., Donahue, Timothy R., Radu, Caius G.

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