Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins von Shirasaki, Ryosuke, Matthews, Geoffrey M., Gandolfi, Sara, de Matos Simoes, Ricardo, Buckley, Dennis L., Raja Vora, Joseline, Sievers, Quinlan L., Brüggenthies, Johanna B., Dashevsky, Olga, Poarch, Haley, Tang, Huihui, Bariteau, Megan A., Sheffer, Michal, Hu, Yiguo, Downey-Kopyscinski, Sondra L., Hengeveld, Paul J., Glassner, Brian J., Dhimolea, Eugen, Ott, Christopher J., Zhang, Tinghu, Kwiatkowski, Nicholas P., Laubach, Jacob P., Schlossman, Robert L., Richardson, Paul G., Culhane, Aedin C., Groen, Richard W.J., Fischer, Eric S., Vazquez, Francisca, Tsherniak, Aviad, Hahn, William C., Levy, Joan, Auclair, Daniel, Licht, Jonathan D., Keats, Jonathan J., Boise, Lawrence H., Ebert, Benjamin L., Bradner, James E., Gray, Nathanael S., Mitsiades, Constantine S.

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Functional Characterization of E3 Ligases and Their Regulators: Therapeutic Implications for Development of New Proteolysis-Targeting Chimeric Degraders of Oncoproteins von Shirasaki, Ryosuke, Gandolfi, Sara, De Matos Simoes, Ricardo, Matthews, Geoffrey M, Buckley, Dennis, Raja, Joseline, Sievers, Quinlan L, Dashevsky, Olga, Poarch, Haley, Tang, Huihui, Bariteau, Megan, Sheffer, Michal, Downey-Kopyscinski, Sondra L., Hengeveld, Paul, Glassner, Brian, Dhimolea, Eugen, Ott, Christopher J., Zhang, Tinghu, Kwiatkowski, Nicholas P, Laubach, Jacob P., Schlossman, Robert L., Richardson, Paul G., Culhane, Aedin, Groen, Richard W.J., Fischer, Eric, Ebert, Benjamin L., Vazquez, Francisca, Tsherniak, Aviad, Hahn, William C., Levy, Joan, Auclair, Daniel, Licht, Jonathan D., Keats, Jonathan J, Boise, Lawrence H., Bradner, James, Gray, Nathanael, Mitsiades, Constantine S.

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Systematic Evaluation of Preclinical Genetically Determined Vs. "Stochastic"/Transient Resistance to High-Dose Melphalan Treatment in Multiple Myeloma von Hengeveld, Paul J., Matthews, Geoffrey M., Hu, Yiguo, Sheffer, Michal, Bariteau, Megan A., Poarch, Haley I., Dhimolea, Eugen, Mitsiades, Constantine S

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CRISPR-Based Functional Genomics Studies Reveal Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins: Implicatio... von Shirasaki, Ryosuke, Gandolfi, Sara, De Matos Simoes, Ricardo, Matthews, Geoffrey, Buckley, Dennis, Dashevsky, Olga, Downey-Kopyscinski, Sondra L., Tang, Huihui, Sheffer, Michal, Dhimolea, Eugen, Glassner, Brian, Bariteau, Megan, Sorrell, Jeffrey, Bruggenthies, Johanna B, Sievers, Quinlan, Poarch, Haley, Kwiatkowski, Nicholas P, Zhang, Tinghu, Laubach, Jacob, Schlossman, Robert L., Richardson, Paul, Culhane, Aedin, Groen, Richard WJ, Fischer, Eric S., Vazquez, Francisca, Tsherniak, Aviad, Hahn, William C., Levy, Joan, Auclair, Daniel, Licht, Jonathan D., Keats, Jonathan J, Boise, Lawrence H., Ebert, Benjamin L., Bradner, James, Gray, Nathanae, Mitsiades, Constantine S.

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Abstract 4713: BET bromodomain degradation as a therapeutic strategy in drug-resistant multiple myeloma von Matthews, Geoffrey M., Hu, Yiguo, Sheffer, Michal, Hengeveld, Paul J., Buckley, Dennis L., Bariteau, Megan A., Poarch, Haley, Bradner, James E., Mitsiades, Constantine S.

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Molecular markers of myeloma cell sensitivity vs. resistance to heterobifunctional degraders of oncoproteins: therapeutic implications von Shirasaki, Ryosuke, de Matos Simoes, Ricardo, Gandolfi, Sara, Matthews, Geoffrey, Buckley, Dennis, Raja, Joseline, Sievers, Quinlan, Bruggenthies, Johanna, Dashevsky, Olga, Poarch, Haley, Tang, Huihui, Bariteau, Megan, Sheffer, Michal, Hu, Yiguo, Downey-Kopyscinski, Sondra, Hengeveld, Paul, Glassner, Brian J., Dhimolea, Eugen, Ott, Christopher, Zhang, Tinghu, Kwiatkowski, Nicholas, Laubach, Jacob, Schlossman, Robert, Culhane, Aedin, Richardson, Paul G., Groen, Richard, Fischer, Eric, Vazquez, Francisca, Tsherniak, Aviad, Hahn, William, Levy, Joan, Auclair, Daniel, Licht, Jonathan, Keats, Jonathan, Boise, Lawrence, Ebert, Benjamin, Bradner, James, Gray, Nathanael, Mitsiades, Constantine

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CRISPR studies identify genes preferentially essential for myeloma cells vs. other neoplasias: implications for future therapies selective against MM von Shirasaki, Ryosuke, de Matos Simoes, Ricardo, Downey-Kopyscinski, Sondra, Matthews, Geoffrey, Hu, Yiguo, Sheffer, Michal, Dhimolea, Eugen, Dashevsky, Olga, Gandolfi, Sara, Hengeveld, Paul, Dempster, Joshua, Meyers, Robin, Bryan, Jordan, Dharia, Neekesh, McFarland, James, Sarkar, Subhashis, Bruggenthies, Johanna, Tang, Huihui, Bariteau, Megan, Aguirre, Andrew, Borah, Minasri, Sievers, Quinlan, Ebert, Benjamin, Raja, Joseline, Glassner, Brian J., Ott, Christopher, Bradner, James, Kwiatkowski, Nicholas, Auclair, Daniel, Levy, Joan, Poarch, Haley, Zhang, Tinghu, Laubach, Jacob, Buckley, Dennis, Schlossman, Robert, Groen, Richard, Fischer, Eric, Richardson, Paul G., Keats, Jonathan, Boise, Lawrence, Licht, Jonathan, Culhane, Aedin, Gray, Nathanael, Hahn, William, Vazquez, Francisca, Tsherniak, Aviad, Mitsiades, Constantine

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