Passive immunotherapies targeting Aβ and tau in Alzheimer's disease von Plotkin, Steven S., Cashman, Neil R.

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Prion-Like Propagation of Protein Misfolding and Aggregation in Amyotrophic Lateral Sclerosis von McAlary, Luke, Plotkin, Steven S, Yerbury, Justin J, Cashman, Neil R

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Misfolding-Associated Exposure of Natively Buried Residues in Mutant SOD1 Facilitates Binding to TRAF6 von Garg, Pranav, Semmler, Sabrina, Baudouin, Charlotte, Vande Velde, Christine, Plotkin, Steven S.

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Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and -independent mechanisms von Grad, Leslie I., Yerbury, Justin J., Turner, Bradley J., Guest, William C., Pokrishevsky, Edward, O'Neill, Megan A., Yanai, Anat, Silverman, Judith M., Zeineddine, Rafaa, Corcoran, Lisa, Kumita, Janet R., Luheshi, Leila M., Yousefi, Masoud, Coleman, Bradley M., Hill, Andrew F., Plotkin, Steven S., Mackenzie, Ian R., Cashman, Neil R.

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As Simple As Possible, but Not Simpler: Exploring the Fidelity of Coarse-Grained Protein Models for Simulated Force Spectroscopy von Habibi, Mona, Rottler, Jörg, Plotkin, Steven S

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Testing the feasibility of targeting a conserved region on the S2 domain of the SARS-CoV-2 spike protein von Garg, Pranav, Hsueh, Shawn C.C., Plotkin, Steven S.

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Ensemble Generation for Linear and Cyclic Peptides Using a Reservoir Replica Exchange Molecular Dynamics Implementation in GROMACS von Hsueh, Shawn C.C., Aina, Adekunle, Plotkin, Steven S.

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Prediction of Misfolding-Specific Epitopes in SOD1 Using Collective Coordinates von Peng, Xubiao, Cashman, Neil R, Plotkin, Steven S

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SOD1 exhibits allosteric frustration to facilitate metal binding affinity von Das, Atanu, Plotkin, Steven S.

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A systematically coarse-grained model for DNA and its predictions for persistence length, stacking, twist, and chirality von Morriss-Andrews, Alex, Rottler, Joerg, Plotkin, Steven S

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Emerging Developments in Targeting Proteotoxicity in Neurodegenerative Diseases von McAlary, Luke, Plotkin, Steven S., Cashman, Neil R.

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Intermolecular transmission of Superoxide dismutase 1 misfolding in living cells von Grad, Leslie I., Guest, Will C., Yanai, Anat, Pokrishevsky, Edward, O'Neill, Megan A., Gibbs, Ebrima, Semenchenko, Valentyna, Yousefi, Masoud, Wishart, David S., Plotkin, Steven S., Cashman, Neil R.

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Cyclization Scaffolding for Improved Vaccine Immunogen Stability: Application to Tau Protein in Alzheimer’s Disease von Hsueh, Shawn C. C., Nijland, Mark, Aina, Adekunle, Plotkin, Steven S.

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PROTHON: A Local Order Parameter-Based Method for Efficient Comparison of Protein Ensembles von Aina, Adekunle, Hsueh, Shawn C. C., Plotkin, Steven S.

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De Novo Design of a β‑Helix Tau Protein Scaffold: An Oligomer-Selective Vaccine Immunogen Candidate for Alzheimer’s Disease von Aina, Adekunle, Hsueh, Shawn C. C., Gibbs, Ebrima, Peng, Xubiao, Cashman, Neil R., Plotkin, Steven S.

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A Rationally Designed Humanized Antibody Selective for Amyloid Beta Oligomers in Alzheimer’s Disease von Gibbs, Ebrima, Silverman, Judith M., Zhao, Beibei, Peng, Xubiao, Wang, Jing, Wellington, Cheryl L., Mackenzie, Ian R., Plotkin, Steven S., Kaplan, Johanne M., Cashman, Neil R.

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The unfolding mechanism of monomeric mutant SOD1 by simulated force spectroscopy von Habibi, Mona, Rottler, Jörg, Plotkin, Steven S.

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Mechanical Probes of SOD1 Predict Systematic Trends in Metal and Dimer Affinity of ALS-Associated Mutants von Das, Atanu, Plotkin, Steven S.

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Soft Vibrational Modes Predict Breaking Events during Force-Induced Protein Unfolding von Habibi, Mona, Plotkin, Steven S., Rottler, Jörg

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Amyloidogenic regions in beta-strands II and III modulate the aggregation and toxicity of SOD1 in living cells von McAlary, Luke, Nan, Jeremy R, Shyu, Clay, Sher, Mine, Plotkin, Steven S, Cashman, Neil R

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