Repurposing EGFR Inhibitor Utility in Colorectal Cancer in Mutant APC and TP53 Subpopulations von Yang, Mingli, Schell, Michael J, Loboda, Andrey, Nebozhyn, Michael, Li, Jiannong, Teer, Jamie K, Pledger, W Jack, Yeatman, Timothy J

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An integrative gene expression signature analysis identifies CMS4 KRAS-mutated colorectal cancers sensitive to combined MEK and SRC targeted therapy von Yang, Mingli, Davis, Thomas B, Pflieger, Lance, Nebozhyn, Michael V, Loboda, Andrey, Wang, Heiman, Schell, Michael J, Thota, Ramya, Pledger, W Jack, Yeatman, Timothy J

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Dasatinib inhibits migration and invasion in diverse human sarcoma cell lines and induces apoptosis in bone sarcoma cells dependent on src kinase for survival von SHOR, Audrey C, KESCHMAN, Elizabeth A, LEE, Francis Y, MURO-CACHO, Carlos, LETSON, G. Douglas, TRENT, Jonathan C, PLEDGER, W. Jack, JOVE, Richard

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MDM2 Acts Downstream of p53 as an E3 Ligase to Promote FOXO Ubiquitination and Degradation von Fu, Wei, Ma, Qiuping, Chen, Lei, Li, Pengfei, Zhang, Mu, Ramamoorthy, Sivapriya, Nawaz, Zafar, Shimojima, Tsukasa, Wang, Hengbin, Yang, Yonghua, Shen, Zheng, Zhang, Yingtao, Zhang, Xiaohong, Nicosia, Santo V., Zhang, Yanping, Pledger, Jack W., Chen, Jiandong, Bai, Wenlong

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Proliferative status regulates HDAC11 mRNA abundance in nontransformed fibroblasts von Bagui, Tapan K, Sharma, Savitha S, Ma, Le, Pledger, W Jack

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Identification of Aurora-A as a Direct Target of E2F3 during G2/M Cell Cycle Progression von He, Lili, Yang, Hua, Ma, Yihong, Pledger, W. Jack, Cress, W. Douglas, Cheng, Jin Q.

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The deubiquitylase USP7 is a novel cyclin F-interacting protein and regulates cyclin F protein stability von Sharma, Savitha S., Pledger, W. Jack, Kondaiah, Paturu

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Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis von Wang, Hong-Gang, Takahashi, Yoshinori, Coppola, Domenico, Matsushita, Norimasa, Cualing, Hernani D, Sun, Mei, Sato, Yuya, Liang, Chengyu, Jung, Jae U, Cheng, Jin Q, Mul, James J, Pledger, W. Jack

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Roscovitine Inhibits Differentiation and Invasion in a Three-Dimensional Skin Reconstruction Model of Metastatic Melanoma von Mohapatra, Subhra, Coppola, Domenico, Riker, Adam I, Pledger, W Jack

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PTPRS Regulates Colorectal Cancer RAS Pathway Activity by Inactivating Erk and Preventing Its Nuclear Translocation von Davis, Thomas B., Yang, Mingli, Schell, Michael J., Wang, Heiman, Ma, Le, Pledger, W. Jack, Yeatman, Timothy J.

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PTPRS drives adaptive resistance to MEK/ERK inhibitors through SRC von Davis, Thomas B, Yang, Mingli, Wang, Heiman, Lee, Changgong, Yeatman, Timothy J, Pledger, W Jack

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Identification of Aurora-A as a direct target of E2F3 during G2/M cell cycle progression von He, Lili, Yang, Hua, Ma, Yihong, Pledger, W. Jack, Cress, W. Douglas, Cheng, Jin Q.

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Assessing needs and assets for building a regional network infrastructure to reduce cancer related health disparities von Wells, Kristen J., Lima, Diana S., Meade, Cathy D., Muñoz-Antonia, Teresita, Scarinci, Isabel, McGuire, Allison, Gwede, Clement K., Pledger, W. Jack, Partridge, Edward, Lipscomb, Joseph, Matthews, Roland, Matta, Jaime, Flores, Idhaliz, Weiner, Roy, Turner, Timothy, Miele, Lucio, Wiese, Thomas E., Fouad, Mona, Moreno, Carlos S., Lacey, Michelle, Christie, Debra W., Price-Haywood, Eboni G., Quinn, Gwendolyn P., Coppola, Domenico, Sodeke, Stephen O., Green, B. Lee, Lichtveld, Maureen Y.

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p53 promotes repair of heterochromatin DNA by regulating JMJD2b and SUV39H1 expression von Zheng, H, Chen, L, Pledger, W J, Fang, J, Chen, J

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Abstract 5789: A novel role of APC-partnering mutations in the sidedness of colorectal cancer survival von Yang, Mingli, Schell, Michael, Loboda, Andrey, Nebozhyn, Michael, Pledger, W. Jack, Yeatman, Timothy

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The Establishment of the First Cancer Tissue Biobank at a Hispanic-Serving Institution: A National Cancer Institute-Funded Initiative between Moffitt Cancer Center in Florida and t... von Flores, Idhaliz, Muñoz-Antonia, Teresita, Matta, Jaime, García, Miosotis, Fenstermacher, David, Gutierrez, Sylvia, Seijo, Edward, Torres-Ruiz, Jose', Pledger, W Jack, Coppola, Domenico

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Loss of p21WAF1/CIP1 accelerates Ras oncogenesis in a transgenic/knockout mammary cancer model von ADNANE, Jalila, JACKSON, Rosalind J, NICOSIA, Santo V, CANTOR, Alan B, PLEDGER, W. Jack, SEBTI, Saïd M

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Abstract 1083: A novel role of SRC in mediating bypass resistance to MEK inhibition in colorectal cancer stem cells von Yang, Mingli, Davis, Thomas B. Davis B., Nebozhyn, Michael V., Loboda, Andrey, Wang, Heiman, Schell, Michael J., Pflieger, Lance, Thota, Ramya, Pledger, W. Jack, Yeatman, Timothy J.

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Loss of nuclear p21(Cip1/WAF1) during neoplastic progression to metastasis in gamma-irradiated p21 hemizygous mice von Engelman, Robert W, Jackson, Rosalind J, Coppola, Domenico, Wharton, Walker, Cantor, Alan B, Pledger, W Jack

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Loss of nuclear p21Cip1/WAF1 during neoplastic progression to metastasis in γ-irradiated p21 hemizygous mice von Engelman, Robert W., Jackson, Rosalind J., Coppola, Domenico, Wharton, Walker, Cantor, Alan B., Pledger, W. Jack

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