The "Liver-First Approach" for Patients with Locally Advanced Rectal Cancer and Synchronous Liver Metastases von Verhoef, Cornelis, van der Pool, Anne E. M, Nuyttens, Joost J, Planting, Andre S. T, Eggermont, Alexander M. M, de Wilt, Johannes H. W

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Cigarette Smoking and Irinotecan Treatment: Pharmacokinetic Interaction and Effects on Neutropenia von VAN DER BOL, Jessica M, MATHIJSSEN, Ron H. J, LOOS, Walter J, FRIBERG, Lena E, VAN SCHAIK, Ron H. N, DE JONGE, Maja J. A, PLANTING, André S. Th, VERWEIJ, Jaap, SPARREBOOM, Alex, DE JONG, Floris A

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A CYP3A4 Phenotype–Based Dosing Algorithm for Individualized Treatment of Irinotecan von van der Bol, Jessica M, Mathijssen, Ron H J, Creemers, Geert-Jan M, Planting, André S Th, Loos, Walter J, Wiemer, Erik A C, Friberg, Lena E, Verweij, Jaap, Sparreboom, Alex, de Jong, Floris A

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Prophylaxis of Irinotecan‐Induced Diarrhea with Neomycin and Potential Role for UGT1A128 Genotype Screening: A Double‐Blind, Randomized, Placebo‐Controlled Study von de Jong, Floris A., Kehrer, Diederik F. S., Mathijssen, Ron H. J., Creemers, Geert‐Jan, de Bruijn, Peter, van Schaik, Ron H. N., Planting, André S. Th, van der Gaast, Ate, Eskens, Ferry A. L. M., Janssen, Jos Th. P., Ruit, Jan B., Verweij, Jaap, Sparreboom, Alex, de Jonge, Maja J. A.

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Phase I and Pharmacokinetic Study of the Dolastatin 10 Analogue TZT-1027, Given on Days 1 and 8 of a 3-Week Cycle in Patients with Advanced Solid Tumors von de Jonge, Maja J A, van der Gaast, Ate, Planting, André S T, van Doorn, Leny, Lems, Aletta, Boot, Inge, Wanders, Jantien, Satomi, Masahiko, Verweij, Jaap

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Phase I and Pharmacologic Study of PKI166, an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, in Patients with Advanced Solid Malignancies von HOEKSTRA, Ronald, DUMEZ, Herlinde, FIDLER, Isaiah J, VAN OOSTEROM, Allan T, VERWEIJ, Jaap, ESKENS, Ferry A. L. M, VAN DER GAAST, Ate, PLANTING, Andre S. T, DE HEUS, Gerda, SIZER, Kurt C, RAVERA, Christina, VAIDYANATHAN, Sujata, BUCANA, Corazon

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Phase I safety, pharmacokinetic, and pharmacogenomic trial of ES-285, a novel marine cytotoxic agent, administered to adult patients with advanced solid tumors von Baird, Richard D, Kitzen, Jos, Clarke, Paul A, Planting, Andre, Reade, Sarah, Reid, Alison, Welsh, Lyndsey, López Lázaro, Luis, de las Heras, Begona, Judson, Ian R, Kaye, Stan B, Eskens, Ferry, Workman, Paul, deBono, Johann S, Verweij, Jaap

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Phase I and Pharmacokinetic Study of the Polyamine Synthesis Inhibitor SAM486A in Combination with 5-Fluorouracil/ Leucovorin in Metastatic Colorectal Cancer von VAN ZUYLEN, Lia, BRIDGEWATER, John, LEDERMANN, Jonathan A, VERWEIJ, Jaap, SPARREBOOM, Alex, ESKENS, Ferry A. L. M, DE BRUIJN, Peter, SKLENAR, Ivo, PLANTING, Andre S. T, CHOI, Les, BOOTLE, Douglas, MUELLER, Christian

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Phase I and Pharmacokinetic Study of Brostallicin (PNU-166196), a New DNA Minor-Groove Binder, Administered Intravenously Every 3 Weeks to Adult Patients with Metastatic Cancer von TEN TIJE, Albert J, VERWEIJ, Jaap, STOTER, Gerrit, PLANTING, Andre S. T, DE JONGE, Maja J. A, SPARREBOOM, Alex, VAN DER GAAST, Ate, FOWST, Camilla, FIORENTINI, Francesco, TURSI, Jennifer, ANTONELLINI, Alessandro, MANTEL, Marijke, HARTMAN, Carla M

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Effects of methimazole on the elimination of irinotecan von van der Bol, Jessica M, Visser, Theo J, Loos, Walter J, de Jong, Floris A, Wiemer, Erik A. C, van Aken, Maarten O, Planting, Andre S, Schellens, Jan H, Verweij, Jaap, Mathijssen, Ron H. J

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The potential of statins as part of anti-cancer treatment von Sleijfer, Stefan, van der Gaast, Ate, Planting, André S.Th, Stoter, Gerrit, Verweij, Jaap

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Body-Surface Area–Based Dosing Does Not Increase Accuracy of Predicting Cisplatin Exposure von DE JONGH, Felix E, VERWEIJ, Jaap, LOOS, Walter J, DE WIT, Ronald, DE JONGE, Maja J. A, PLANTING, André S. T, NOOTER, Kees, STOTER, Gerrit, SPARREBOOM, Alex

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Phase I and Pharmacologic Study of the Novel Indoloquinone Bioreductive Alkylating Cytotoxic Drug E09 von Schellens, Jan H. M., Planting, Andre S. Th, van Acker, Bernadette A.C., Loos, Walter J., Boer-Dennert, Maureen de, van der Burg, Maria E.L., Koier, Ineke, Krediet, Raymond T., Stoter, Gerrit, Verweij, Jaap

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A Comparison of Clinical Pharmacodynamics of Different Administration Schedules of Oral Topotecan (Hycamtin) von GERRITS, C. J. H, SCHELLENS, J. H. M, VON HOFF, D. D, VERWEIJ, J, BURRIS, H, ECKARDT, J. R, PLANTING, A. S. T, VAN DER BURG, M. E. L, RODRIGUEZ, G. I, LOOS, W. J, VAN BEURDEN, V, HUDSON, I

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Phase I Pharmacologic Study of Oral Topotecan and Intravenous Cisplatin: Sequence-Dependent Hematologic Side Effects von DE JONGE, M. J. A, LOOS, W. J, HEARN, S, ROSS, G, VERWEIJ, J, GELDERBLOM, H, PLANTING, A. S. T, VAN DER BURG, M. E. L, SPARREBOOM, A, BROUWER, E, VAN BEURDEN, V, MANTEL, M. A, DOYLE, E

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Phase I and Pharmacologic Study of Oral ZD9331, A Novel Nonpolyglutamated Thymidylate Synthase Inhibitor, in Adult Patients With Solid Tumors von DE JONGE, Maja J. A, PUNT, Cornelis J. A, SPARREBOOM, Alex, PLANTING, André S. T, PETERS, M. E. W. J, VAN DE SCHRAAF, Jacqueline, JACKMAN, Ann, SMITH, Rob, DE MULDER, Pieter H. M, VERWEIJ, Jaap

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Clinical pharmacokinetics of doxorubicin in combination with GF120918, a potent inhibitor of MDR1 P-glycoprotein von Sparreboom, Alex, Planting, André ST, Jewell, Roxanne C, van der Burg, Maria EL, van der Gaast, Ate, de Bruijn, Peter, Loos, Walter J, Nooter, Kees, Chandler, LuWanda H, Paul, Elaine M, Wissel, Paul S, Verweij, Jaap

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Docetaxel and paclitaxel inhibit DNA-adduct formation and intracellular accumulation of cisplatin in human leukocytes von MA, J, VERWEIJ, J, PLANTING, A. S. T, KOLKER, H. J, LOOS, W. J, DE BOER-DENNERT, M, VAN DER BURG, M. E. L, STOTER, G, SCHELLENS, J. H. M

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Phase I Study of 3-Week Schedule of Irinotecan Combined With Cisplatin in Patients With Advanced Solid Tumors von DE JONGE, M. J. A, SPARREBOOM, A, PLANTING, A. S. T, VAN DER BURG, M. E. L, DE BOER-DENNERT, M. M, TER STEEG, J, JACQUES, C, VERWEIJ, J

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Determination of Doxorubicin and Doxorubicinol in Plasma of Cancer Patients by High-Performance Liquid Chromatography von de Bruijn, Peter, Verweij, Jaap, Loos, Walter J., Kolker, Herman J., Planting, André S.T., Nooter, Kees, Stoter, Gerrit, Sparreboom, Alex

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