Discovery of RG7112: A Small-Molecule MDM2 Inhibitor in Clinical Development von Vu, Binh, Wovkulich, Peter, Pizzolato, Giacomo, Lovey, Allen, Ding, Qingjie, Jiang, Nan, Liu, Jin-Jun, Zhao, Chunlin, Glenn, Kelli, Wen, Yang, Tovar, Christian, Packman, Kathryn, Vassilev, Lyubomir, Graves, Bradford

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Discovery of a Highly Potent, Orally Active Mitosis/Angiogenesis Inhibitor R1530 for the Treatment of Solid Tumors von Liu, Jin-Jun, Higgins, Brian, Ju, Grace, Kolinsky, Kenneth, Luk, Kin-Chun, Packman, Kathryn, Pizzolato, Giacomo, Ren, Yi, Thakkar, Kshitij, Tovar, Christian, Zhang, Zhuming, Wovkulich, Peter M

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Pyrazolobenzodiazepines: Part I. Synthesis and SAR of a potent class of kinase inhibitors von Liu, Jin-Jun, Daniewski, Irena, Ding, Qingjie, Higgins, Brian, Ju, Grace, Kolinsky, Kenneth, Konzelmann, Fred, Lukacs, Christine, Pizzolato, Giacomo, Rossman, Pamela, Swain, Amy, Thakkar, Kshitij, Wei, Chung-Chen, Miklowski, Dorota, Yang, Hong, Yin, Xuefeng, Wovkulich, Peter M.

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Olefinic nitrone and nitrile oxide [3 + 2] cycloadditions. A short stereospecific synthesis of biotin from cycloheptene von Confalone, Pat N, Pizzolato, Giacomo, Lollar-Confalone, Dianne, Uskokovic, Milan R

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Use of intramolecular [3 + 2] cycloaddition reactions in the synthesis of natural products. A stereospecific synthesis of (.+-.)-biotin from cycloheptene von Confalone, Pat N, Lollar, E. Dianne, Pizzolato, Giacomo, Uskokovic, Milan R

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Total synthesis of racemic ajmalicine and 19-epi-ajmalicine von Gutzwiller, Jürg, Pizzolato, Giacomo, Uskoković, Milan R.

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Total stereospecific synthesis of (.+-.)-aklavinone von Confalone, Pat N, Pizzolato, Giacomo

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The synthesis of novel antitumor antibiotics structurally related to the anthracyclinones von Confalone, Pat N, Pizzolato, Giacomo

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2,4,5-TRIPHENYL IMIDAZOLINE DERIVATIVES AS INHIBITORS OF THE INTERACTION BETWEEN P53 AND MDM2 PROTEINS FOR USE AS ANTICANCER AGENTS von LIU, JIN-JUN, LOVEY, ALLEN JOHN, KONG, NORMAN, PIZZOLATO, GIACOMO, GRAVES, BRADFORD JAMES, WOVKULICH, PETER MICHAEL, SO, SUNG-SAU, ROBERTS, JOHN LAWSON, VU, BINH THANH, DING, QINGJIE

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Total synthesis of pseudomonic acid C von Barrish, Joel C, Lee, Hsi Lin, Mitt, Toomas, Pizzolato, Giacomo, Baggiolini, Enrico G, Uskokovic, Milan R

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Synthesis of d-biotin from L-cystine via intramolecular [3+2]cycloaddition von Baggiolini, Enrico G, Lee, Hsi Lin, Pizzolato, Giacomo, Uskokovic, Milan R

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Stereocontrolled synthesis of 19-epiajmalicine from loganin aglucone von Baggiolini, Enrico G., Pizzolato, Giacomo, Uskoković, Milan R.

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2,4,5-TRIPHENYL IMIDAZOLINE DERIVATIVES AS INHIBITORS OF THE INTERACTION BETWEEN P53 AND MDM2 PROTEINS FOR USE AS ANTICANCER AGENTS von LIU, JIN-JUN, LOVEY, ALLEN JOHN, KONG, NORMAN, PIZZOLATO, GIACOMO, GRAVES, BRADFORD JAMES, WOVKULICH, PETER MICHAEL, SO, SUNG-SAU, ROBERTS, JOHN LAWSON, VU, BINH THANH, DING, QINGJIE

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2,4,5-TRIPHENYL IMIDAZOLINE DERIVATIVES AS INHIBITORS OF THE INTERACTION BETWEEN P53 AND MDM2 PROTEINS FOR USE AS ANTICANCER AGENTS von LIU, JIN-JUN, LOVEY, ALLEN JOHN, KONG, NORMAN, PIZZOLATO, GIACOMO, GRAVES, BRADFORD JAMES, WOVKULICH, PETER MICHAEL, SO, SUNG-SAU, ROBERTS, JOHN LAWSON, VU, BINH THANH, DING, QINGJIE

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PYRAZOLOBENZODIAZEPINES AS CDK2 INHIBITORS von WOVKULICH PETER MICHAEL, DING QINGJIE, MADISON VINCENT STEWART, PIZZOLATO GIACOMO, WEI CHUNGN, LIU JIN-JUN

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Method for synthesizing pyrazolobenzodiazepines von WOVKULICH PETER MICHAEL, DING QINGJIE, PIZZOLATO GIACOMO, LIU JIN-JUN

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Method for synthesizing pyrazolobenzodiazepines von Ding, Qingjie, Liu, Jin-Jun, Pizzolato, Giacomo, Wovkulich, Peter Michael

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Disubstituted pyrazolobenzodiazepines useful as inhibitors for CDK2 and angiogenesis, and for the treatment of breast, colon, lung and prostate cancer von LIU, JIN-JUN, REN, YI, PIZZOLATO, GIACOMO, ZHANG, ZHUMING, THAKKAR, KSHITIJ CHHABILBHAI, WOVKULICH, PETER MICHAEL, LUK, KINUN

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2,4,5-triphenyl imidazoline derivatives as inhibitors of the interaction between P53 and MDM2 proteins for use as anticancer agents von LIU, JIN-JUN, LOVEY, ALLEN JOHN, KONG, NORMAN, PIZZOLATO, GIACOMO, GRAVES, BRADFORD JAMES, WOVKULICH, PETER MICHAEL, SO, SUNG-SAU, ROBERTS, JOHN LAWSON, VU, BINH THANH, DING, QINGJIE

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PYRAZOLOBENZODIAZEPINES AS CDK2 INHIBITORS von LIU, JIN-JUN, PIZZOLATO, GIACOMO, MADISON, VINCENT STEWART, WEI, CHUNGN, WOVKULICH, PETER MICHAEL, DING, QINGJIE

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