2-Arylbenzoxazoles as CETP inhibitors: Raising HDL-C in cynoCETP transgenic mice von Kallashi, Florida, Kim, Dooseop, Kowalchick, Jennifer, Park, You Jung, Hunt, Julianne A., Ali, Amjad, Smith, Cameron J., Hammond, Milton L., Pivnichny, James V., Tong, Xinchun, Xu, Suoyu S., Anderson, Matt S., Chen, Ying, Eveland, Suzanne S., Guo, Qiu, Hyland, Sheryl A., Milot, Denise P., Cumiskey, Anne-Marie, Latham, Melanie, Peterson, Laurence B., Rosa, Raymond, Sparrow, Carl P., Wright, Samuel D., Sinclair, Peter J.

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Design and synthesis of potent, orally bioavailable dihydroquinazolinone inhibitors of p38 MAP kinase von Stelmach, John E., Liu, Luping, Patel, Sangita B., Pivnichny, James V., Scapin, Giovanna, Singh, Suresh, Hop, Cornelis E.C.A., Wang, Zhen, Strauss, John R., Cameron, Patricia M., Nichols, Elizabeth A., O'Keefe, Stephen J., O'Neill, Edward A., Schmatz, Dennis M., Schwartz, Cheryl D., Thompson, Chris M., Zaller, Dennis M., Doherty, James B.

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Effect of Signal Interference from Dosing Excipients on Pharmacokinetic Screening of Drug Candidates by Liquid Chromatography/Mass Spectrometry von Tong, Xinchun S, Wang, Junying, Zheng, Song, Pivnichny, James V, Griffin, Patrick R, Shen, Xiaolan, Donnelly, Marcie, Vakerich, Ken, Nunes, Chris, Fenyk-Melody, Judy

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Biphenyl-Substituted Oxazolidinones as Cholesteryl Ester Transfer Protein Inhibitors: Modifications of the Oxazolidinone Ring Leading to the Discovery of Anacetrapib von Smith, Cameron J, Ali, Amjad, Hammond, Milton L, Li, Hong, Lu, Zhijian, Napolitano, Joann, Taylor, Gayle E, Thompson, Christopher F, Anderson, Matt S, Chen, Ying, Eveland, Suzanne S, Guo, Qiu, Hyland, Sheryl A, Milot, Denise P, Sparrow, Carl P, Wright, Samuel D, Cumiskey, Anne-Marie, Latham, Melanie, Peterson, Laurence B, Rosa, Ray, Pivnichny, James V, Tong, Xinchun, Xu, Suoyu S, Sinclair, Peter J

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2-Arylbenzoxazoles as CETP inhibitors: Substitution and modification of the α-alkoxyamide moiety von Hunt, Julianne A., Gonzalez, Silvia, Kallashi, Florida, Hammond, Milton L., Pivnichny, James V., Tong, Xinchun, Xu, Suoyu S., Anderson, Matt S., Chen, Ying, Eveland, Suzanne S., Guo, Qiu, Hyland, Sheryl A., Milot, Denise P., Sparrow, Carl P., Wright, Samuel D., Sinclair, Peter J.

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High throughput metabolic stability screen for lead optimization in drug discovery von Tong, Xinchun S., Xu, Suoyu, Zheng, Song, Pivnichny, James V., Martin, Jesus, Dufresne, Claude

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The discovery of a potent and selective lethal factor inhibitor for adjunct therapy of anthrax infection von Xiong, Yusheng, Wiltsie, Judyann, Woods, Andrea, Guo, Jian, Pivnichny, James V., Tang, Wei, Bansal, Alka, Cummings, Richard T., Cunningham, Barry R., Friedlander, Arthur M., Douglas, Cameron M., Salowe, Scott P., Zaller, Dennis M., Scolnick, Edward M., Schmatz, Dennis M., Bartizal, Kenneth, Hermes, Jeffrey D., MacCoss, Malcolm, Chapman, Kevin T.

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A simple in vitro model to study the stability of acylglucuronides von Chen, Zhesheng, Holt, Tom G., Pivnichny, James V., Leung, Kwan

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p38 Inhibitors: piperidine- and 4-aminopiperidine-substituted naphthyridinones, quinolinones, and dihydroquinazolinones von Hunt, Julianne A, Kallashi, Florida, Ruzek, Rowena D, Sinclair, Peter J, Ita, Ida, McCormick, Sherrie X, Pivnichny, James V, Hop, C.E.C.A, Kumar, Sanjeev, Wang, Zhen, O'Keefe, Stephen J, O'Neill, Edward A, Porter, Gene, Thompson, James E, Woods, Andrea, Zaller, Dennis M, Doherty, James B

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High-throughput pharmacokinetics screen of VLA-4 antagonists by LC/MS/MS coupled with automated solid-phase extraction sample preparation von Tong, Xinchun S, Wang, Junying, Zheng, Song, Pivnichny, James V

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Antagonists of human CCR5 receptor containing 4-(pyrazolyl)piperidine side chains. Part 2: Discovery of potent, selective, and orally bioavailable compounds von SHEN, Dong-Ming, MIN SHU, GOULD, Sandra L, DEMARTINO, Julie A, SICILIANO, Salvatore J, LYONS, Kathy, PIVNICHNY, James V, KWEI, Gloria Y, CARELLA, Anthony, CARVER, Gwen, HOLMES, Karen, SCHLEIF, William A, WILLOUGHBY, Christopher A, DANZEISEN, Renee, HAZUDA, Daria, KESSLER, Joseph, LINEBERGER, Janet, MILLER, Michael D, EMINI, Emilio A, SHAH, Shrenik, LYNCH, Christopher L, HALE, Jeffrey J, MILLS, Sander G, CHAPMAN, Kevin T, MALKOWITZ, Lorraine, SPRINGER, Martin S

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p38 MAP kinase inhibitors: Metabolically stabilized piperidine-substituted quinolinones and naphthyridinones von Bao, Jianming, Hunt, Julianne A., Miao, Shouwu, Rupprecht, Kathleen M., Stelmach, John E., Liu, Luping, Ruzek, Rowena D., Sinclair, Peter J., Pivnichny, James V., Hop, Cornelis E.C.A., Kumar, Sanjeev, Zaller, Dennis M., Shoop, Wesley L., O’Neill, Edward A., O’Keefe, Stephen J., Thompson, Chris M., Cubbon, Rose M., Wang, Ruixiu, Zhang, Wen Xiao, Thompson, James E., Doherty, James B.

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Antagonists of human CCR5 receptor containing 4-(pyrazolyl)piperidine side chains. Part 3: SAR studies on the benzylpyrazole segment von MIN SHU, LOEBACH, Jennifer L, SICILIANO, Salvatore J, DI SALVO, Jerry, LYONS, Kathy, PIVNICHNY, James V, KWEI, Gloria Y, CARELLA, Anthony, CARVER, Gwen, HOLMES, Karen, SCHLEIF, William A, DANZEISEN, Renee, PARKER, Kerry A, HAZUDA, Daria, KESSLER, Joseph, LINEBERGER, Janet, MILLER, Michael D, EMINI, Emilio A, MILLS, Sander G, CHAPMAN, Kevin T, SHEN, Dong-Ming, MALKOWITZ, Lorraine, SPRINGER, Martin S, GOULD, Sandra L, DEMARTINO, Julie A

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Simple and sensitive liquid chromatography/tandem mass spectrometry method for the determination of diazepam and its major metabolites in rat cerebrospinal fluid von Wang, Junying, Shen, Xiaolan, Fenyk-Melody, Judy, Pivnichny, James V., Tong, Xinchun

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Rapid pharmacokinetic screening for the selection of new drug discovery candidates using a generic isocratic liquid chromatography–atmospheric pressure ionization tandem mass spect... von Colwell, Lawrence F., Tamvakopoulos, Constantin S., Wang, Pei Ran, Pivnichny, James V., Shih, Thomas L.

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Synthesis of Nodulisporic Acid 2‘ ‘-Oxazoles and 2‘ ‘-Thiazoles von Berger, Richard, Shoop, Wesley L, Pivnichny, James V, Warmke, Lynn M, Zakson-Aiken, Michelle, Owens, Karen A, deMontigny, Pierre, Schmatz, Dennis M, Wyvratt, Matthew J, Fisher, Michael H, Meinke, Peter T, Colletti, Steven L

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Potent, orally absorbed glucagon receptor antagonists von de Laszlo, Stephen E., Hacker, Candice, Li, Bing, Kim, Dooseop, MacCoss, Malcolm, Mantlo, Nathan, Pivnichny, James V., Colwell, Larry, Koch, Gregory E., Cascieri, Margaret A., Hagmann, William K.

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Discovery of N-{N-[(3-Cyanophenyl)sulfonyl]-4(R)-cyclobutylamino-(l)-prolyl}-4-[(3′,5′-dichloroisonicotinoyl)amino]-(l)-phenylalanine (MK-0668), an Extremely Potent and Orally Acti... von Lin, Linus S, Lanza, Thomas, Jewell, James P, Liu, Ping, Jones, Carrie, Kieczykowski, Gerard R, Treonze, Kelly, Si, Qian, Manior, Salony, Koo, Gloria, Tong, Xinchun, Wang, Junying, Schuelke, Anne, Pivnichny, James, Wang, Regina, Raab, Conrad, Vincent, Stella, Davies, Philip, MacCoss, Malcolm, Mumford, Richard A, Hagmann, William K

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Base-catalyzed isomerization of avermectins von Pivnichny, James V, Arison, Byron H, Preiser, Franz A, Shim, Jung Sook K, Mrozik, Helmut

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2-Arylbenzoxazoles as CETP inhibitors: Substitution and modification of the a-alkoxyamide moiety von Hunt, Julianne A, Gonzalez, Silvia, Kallashi, Florida, Hammond, Milton L, Pivnichny, James V, Tong, Xinchun, Xu, Suoyu S, Anderson, Matt S, Chen, Ying, Eveland, Suzanne S, Guo, Qiu, Hyland, Sheryl A, Milot, Denise P, Sparrow, Carl P, Wright, Samuel D, Sinclair, Peter J

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