First-in-Human Trial of a Novel Anti-Trop-2 Antibody-SN-38 Conjugate, Sacituzumab Govitecan, for the Treatment of Diverse Metastatic Solid Tumors von Starodub, Alexander N, Ocean, Allyson J, Shah, Manish A, Guarino, Michael J, Picozzi, Jr, Vincent J, Vahdat, Linda T, Thomas, Sajeve S, Govindan, Serengulam V, Maliakal, Pius P, Wegener, William A, Hamburger, Steven A, Sharkey, Robert M, Goldenberg, David M

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Therapy of Small Cell Lung Cancer (SCLC) with a Topoisomerase-I-inhibiting Antibody-Drug Conjugate (ADC) Targeting Trop-2, Sacituzumab Govitecan von Gray, Jhanelle E, Heist, Rebecca S, Starodub, Alexander N, Camidge, D Ross, Kio, Ebenezer A, Masters, Gregory A, Purcell, W Thomas, Guarino, Michael J, Misleh, Jamal, Schneider, Charles J, Schneider, Bryan J, Ocean, Allyson, Johnson, Tirrell, Gandhi, Leena, Kalinsky, Kevin, Scheff, Ronald, Messersmith, Wells A, Govindan, Serengulam V, Maliakal, Pius P, Mudenda, Boyd, Wegener, William A, Sharkey, Robert M, Goldenberg, David M

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Inhibition of carcinogenesis by tea von Yang, Chung S, Maliakal, Pius, Meng, Xiaofeng

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Urinary and Plasma Levels of Resveratrol and Quercetin in Humans, Mice, and Rats after Ingestion of Pure Compounds and Grape Juice von Meng, Xiaofeng, Maliakal, Pius, Lu, Hong, Lee, Mao-Jung, Yang, Chung S

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Pharmacokinetics of dacarbazine and unesbulin and CYP1A2‐mediated drug interactions in patients with leiomyosarcoma von Gao, Lan, Kaushik, Diksha, Van Tine, Brian A., Ingham, Matthew A., Attia, Steven, Meyer, Christian F., Schwartz, Gary K., Maliakal, Pius, Baird, John D., Ma, Jiyuan, Barrett, Rosemary, D'Silva, Dhiren, O'Keefe, Kylie, Kong, Ronald

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Environmental factors in causing human cancers: emphasis on tumorigenesis von Sankpal, Umesh T., Pius, Hima, Khan, Moeez, Shukoor, Mohammed I., Maliakal, Pius, Lee, Chris M., Abdelrahim, Maen, Connelly, Sarah F., Basha, Riyaz

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Effect of herbal teas on hepatic drug metabolizing enzymes in rats von Maliakal, Pius P., Wanwimolruk, Sompon

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Delivery of tea polyphenols to the oral cavity by green tea leaves and black tea extract von LEE, Mao-Jung, LAMBERT, Joshua D, PRABHU, Saileta, XIAOFENG MENG, HONG LU, MALIAKAL, Pius, HO, Chi-Tang, YANG, Chung S

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Tea consumption modulates hepatic drug metabolizing enzymes in Wistar rats von Maliakal, Pius P., Coville, Peter F., Wanwimolruk, Sompon

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Efficacy and Safety of Anti-Trop-2 Antibody Drug Conjugate Sacituzumab Govitecan (IMMU-132) in Heavily Pretreated Patients With Metastatic Triple-Negative Breast Cancer von Bardia, Aditya, Mayer, Ingrid A, Diamond, Jennifer R, Moroose, Rebecca L, Isakoff, Steven J, Starodub, Alexander N, Shah, Nikita C, O'Shaughnessy, Joyce, Kalinsky, Kevin, Guarino, Michael, Abramson, Vandana, Juric, Dejan, Tolaney, Sara M, Berlin, Jordan, Messersmith, Wells A, Ocean, Allyson J, Wegener, William A, Maliakal, Pius, Sharkey, Robert M, Govindan, Serengulam V, Goldenberg, David M, Vahdat, Linda T

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Sacituzumab govitecan (IMMU‐132), an anti‐Trop‐2‐SN‐38 antibody‐drug conjugate for the treatment of diverse epithelial cancers: Safety and pharmacokinetics von Ocean, Allyson J., Starodub, Alexander N., Bardia, Aditya, Vahdat, Linda T., Isakoff, Steven J., Guarino, Michael, Messersmith, Wells A., Picozzi, Vincent J., Mayer, Ingrid A., Wegener, William A., Maliakal, Pius, Govindan, Serengulam V., Sharkey, Robert M., Goldenberg, David M.

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Therapy of Advanced Non-Small-Cell Lung Cancer With an SN-38-Anti-Trop-2 Drug Conjugate, Sacituzumab Govitecan von Heist, Rebecca Suk, Guarino, Michael J, Masters, Gregory, Purcell, W Thomas, Starodub, Alexander N, Horn, Leora, Scheff, Ronald J, Bardia, Aditya, Messersmith, Wells A, Berlin, Jordan, Ocean, Allyson J, Govindan, Serengulam V, Maliakal, Pius, Mudenda, Boyd, Wegener, William A, Sharkey, Robert M, Goldenberg, David M, Camidge, D Ross

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A phase 1b study of unesbulin (PTC596) plus dacarbazine for the treatment of patients with locally recurrent, unresectable, or metastatic relapsed/refractory leiomyosarcoma von Van Tine, Brian Andrew, Ingham, Matthew, Attia, Steven, Meyer, Christian Frederick, Baird, John, D'Silva, Dhiren, O'Keefe, Kylie, Maliakal, Pius, Wahba, Mona M., Weetall, Marla, Schwartz, Gary K.

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Pharmacokinetics of tea catechins after ingestion of green tea and (-)-epigallocatechin-3-gallate by humans: Formation of different metabolites and individual variability von LEE, Mao-Jung, MALIAKAL, Pius, LAISHUN CHEN, XIAOFENG MENG, BONDOC, Flordeliza Y, PRABHU, Saileta, LAMBERT, George, MOHR, Sandra, YANG, Chung S

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Electrolyte and protein imbalance following anti-EGFR therapy in cancer patients: A comparative study von MALIAKAL, PIUS, LEDFORD, ANDREA

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DIPG-54. UPDATED FINDINGS FROM THE PHASE IB STUDY OF UNESBULIN (PTC596) IN CHILDREN WITH NEWLY-DIAGNOSED DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) AND HIGH-GRADE GLIOMA (HGG): A REPO... von Lazow, Margot, Baxter, Patricia, Stanek, Joseph, Rodriguez, Diana, Kumar, Shiva Senthil, Palmer, Joshua, Leach, James, Mikael, Leonie, Thomas, Diana, Fuller, Christine, Boué, Daniel, Pierson, Christopher, Breneman, John, Li, Xiao-Nan, Salloum, Ralph, Ashley, David, de Blank, Peter, Hwang, Eugene, Leary, Sarah, Plant, Ashley, Fisher, Michael, Chi, Susan, Crabtree, Dorothy, Murali, Mythili, Weetall, Marla, Rance, Mark, Maliakal, Pius, Baird, John, D’Silva, Dhiren, O’Keefe, Kylie, Leonard, Jeffrey, Stewart, Clinton, Mardis, Elaine, Fouladi, Maryam, Drissi, Rachid

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EPCT-16. A PHASE IB STUDY OF PTC596 IN CHILDREN WITH NEWLY DIAGNOSED DIFFUSE INTRINSIC PONTINE GLIOMA AND HIGH GRADE GLIOMA von Smiley, Natasha Pillay, Baxter, Patricia, Kumar, Shiva, Hwang, Eugene, Breneman, John, Lane, Adam, Doughman, Renee, Deutsch, Michelle, Stevenson, Charles, Stewart, Clinton, Leach, Jim, Li, Xiao-Nan, Romero, Sonia, Maliakal, Pius, Gao, Lan, Fouladi, Maryam, Drissi, Rachid

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Abstract 3734: Pharmacokinetics of sacituzumab govitecan (IMMU-132), an antibody-drug conjugate (ADC) targeting Trop-2, in patients with diverse advanced solid tumors von Sharkey, Robert M., Ocean, Allyson J., Starodub, Alexander N., Bardia, Aditya, Guarino, Michael, Messersmith, Wells A., Berlin, Jordan D., Picozzi, Vincent J., Moroose, Rebecca, Wegener, William A., Maliakal, Pius, Govindan, Serengulam V., Goldenberg, David M.

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Small molecule tolfenamic acid inhibits PC-3 cell proliferation and invasion in vitro, and tumor growth in orthotopic mouse model for prostate cancer von Sankpal, Umesh T., Abdelrahim, Maen, Connelly, Sarah F., Lee, Chris M., Madero-Visbal, Rafael, Colon, Jimmie, Smith, Joshua, Safe, Stephen, Maliakal, Pius, Basha, Riyaz

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Tolfenamic acid inhibits neuroblastoma cell proliferation and induces apoptosis: A novel therapeutic agent for neuroblastoma von Eslin, Don, Sankpal, Umesh T., Lee, Chris, Sutphin, Robert M., Maliakal, Pius, Currier, Erika, Sholler, Giselle, Khan, Moeez, Basha, Riyaz

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