Immunomodulatory Effects of Lenvatinib Plus Anti–Programmed Cell Death Protein 1 in Mice and Rationale for Patient Enrichment in Hepatocellular Carcinoma von Torrens, Laura, Montironi, Carla, Puigvehí, Marc, Mesropian, Agavni, Leslie, Jack, Haber, Philipp K., Maeda, Miho, Balaseviciute, Ugne, Willoughby, Catherine E., Abril‐Fornaguera, Jordi, Piqué‐Gili, Marta, Torres‐Martín, Miguel, Peix, Judit, Geh, Daniel, Ramon‐Gil, Erik, Saberi, Behnam, Friedman, Scott L., Mann, Derek A., Sia, Daniela, Llovet, Josep M.

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Molecular characterisation of hepatocellular carcinoma in patients with non-alcoholic steatohepatitis von Pinyol, Roser, Torrecilla, Sara, Wang, Huan, Montironi, Carla, Piqué-Gili, Marta, Torres-Martin, Miguel, Wei-Qiang, Leow, Willoughby, Catherine E., Ramadori, Pierluigi, Andreu-Oller, Carmen, Taik, Patricia, Lee, Youngmin A., Moeini, Agrin, Peix, Judit, Faure-Dupuy, Suzanne, Riedl, Tobias, Schuehle, Svenja, Oliveira, Claudia P., Alves, Venancio A., Boffetta, Paolo, Lachenmayer, Anja, Roessler, Stephanie, Minguez, Beatriz, Schirmacher, Peter, Dufour, Jean-François, Thung, Swan N., Reeves, Helen L., Carrilho, Flair J., Chang, Charissa, Uzilov, Andrew V., Heikenwalder, Mathias, Sanyal, Arun, Friedman, Scott L., Sia, Daniela, Llovet, Josep M.

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Cabozantinib Enhances Anti-PD1 Activity and Elicits a Neutrophil-Based Immune Response in Hepatocellular Carcinoma von Esteban-Fabró, Roger, Willoughby, Catherine E, Piqué-Gili, Marta, Montironi, Carla, Abril-Fornaguera, Jordi, Peix, Judit, Torrens, Laura, Mesropian, Agavni, Balaseviciute, Ugne, Miró-Mur, Francesc, Mazzaferro, Vincenzo, Pinyol, Roser, Llovet, Josep M

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Oncogenic role of PMEPA1 and its association with immune exhaustion and TGF-β activation in HCC von Piqué-Gili, Marta, Andreu-Oller, Carmen, Mesropian, Agavni, Esteban-Fabró, Roger, Bárcena-Varela, Marina, Ruiz de Galarreta, Marina, Montironi, Carla, Martinez-Quetglas, Iris, Cappuyns, Sarah, Peix, Judit, Keraite, Ieva, Gris-Oliver, Albert, Fernández-Martínez, Elisa, Mauro, Ezequiel, Torres-Martin, Miguel, Abril-Fornaguera, Jordi, Lindblad, Katherine E., Lambrechts, Diether, Dekervel, Jeroen, Thung, Swan N., Sia, Daniela, Lujambio, Amaia, Pinyol, Roser, Llovet, Josep M.

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Imaging Calcium in Hippocampal Presynaptic Terminals With a Ratiometric Calcium Sensor in a Novel Transgenic Mouse von Al-Osta, Ibrahim, Mucha, Mariusz, Pereda, Daniel, Piqué-Gili, Marta, Okorocha, Albert E, Thomas, Roisin, Hartell, Nicholas A

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Corrigendum: Imaging Calcium in Hippocampal Presynaptic Terminals With a Ratiometric Calcium Sensor in a Novel Transgenic Mouse von Al-Osta, Ibrahim, Mucha, Mariusz, Pereda, Daniel, Piqué-Gili, Marta, Okorocha, Albert E, Thomas, Roisin, Hartell, Nicholas A

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Applications of single-cell multi-omics in liver cancer von Peeters, Frederik, Cappuyns, Sarah, Piqué-Gili, Marta, Phillips, Gino, Verslype, Chris, Lambrechts, Diether, Dekervel, Jeroen

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Predicting response to atezolizumab plus bevacizumab in advanced hepatocellular carcinoma using single-cell RNA-sequencing-derived gene signatures von Cappuyns, Sarah, Piqué-Gili, Marta, Esteban-Fabró, Roger, Philips, Gino, Pinyol, Roser, Vandecaveye, Vincent, Abril-Fornaguera, Jordi, Haber, Philipp, Verslype, Chris, Van Cutsem, Eric, Lambrechts, Diether, Villanueva, Augusto, Dekervel, Jeroen, Llovet, Josep

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OS-059-YI - Predicting response to atezolizumab plus bevacizumab in advanced hepatocellular carcinoma using single-cell RNA-sequencing-derived gene signatures von Cappuyns, Sarah, Piqué-Gili, Marta, Esteban-Fabró, Roger, Philips, Gino, Pinyol, Roser, Vandecaveye, Vincent, Abril-Fornaguera, Jordi, Haber, Philipp, Verslype, Chris, Van Cutsem, Eric, Lambrechts, Diether, Villanueva, Augusto, Dekervel, Jeroen, Llovet, Josep

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Applications of single-cell multi-omics in liver cancerKey points von Frederik Peeters, Sarah Cappuyns, Marta Piqué-Gili, Gino Phillips, Chris Verslype, Diether Lambrechts, Jeroen Dekervel

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PMEPA1: an oncogene in hepatocellular carcinoma linked to TGF-beta signaling von Andreu-Oller, Carmen, Piqué-Gili, Marta, Barcena-Varela, Marina, Pinyol, Roser, Esteban-Fabró, Roger, Peix, Judit, Lindblad, Katherine E., Torres-Martín, Miguel, Sia, Daniela, Lujambio, Amaia, Llovet, Josep M.

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TOP-507-YI Single-cell RNA sequencing-derived gene signatures reveal distinct response mechanisms to atezolizumab + bevacizumab in advanced hepatocellular carcinoma von Cappuyns, Sarah, Piqué-Gili, Marta, Esteban-Fabró, Roger, Philips, Gino, Pinyol, Roser, Gris-Oliver, Albert, Vandecaveye, Vincent, Abril-Fornaguera, Jordi, Montironi, Carla, Bassaganyas, Laia, Peix, Judit, Zeitlhoefler, Marcus, Mesropian, Agavni, Huguet-Pradell, Júlia, Haber, Philipp, Mohr, Raphael, Meyer, Tim, Reeves, Helen Louise, Edeline, Julien, Finkelmeier, Fabian, Trojan, Jörg, Galle, Peter R., Foerster, Friedrich, Minguez, Beatriz, Montal, Robert, Heikenwälder, Mathias, Verslype, Chris, Van Cutsem, Eric, Lambrechts, Diether, Villanueva, Augusto, Dekervel, Jeroen, Llovet, Josep

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AS053 - Cabozantinib enhances the efficacy and immune modulatory activity of anti-PD1 therapy in a syngeneic mouse model of hepatocellular carcinoma von Esteban-Fabró, Roger, Willoughby, Catherine E., Piqué-Gili, Marta, Peix, Judit, Montironi, Carla, Abril-Fornaguera, Jordi, Torrens, Laura, Pinyol, Roser, Llovet, Josep M.

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Cabozantinib enhances the efficacy and immune modulatory activity of anti-PD1 therapy in a syngeneic mouse model of hepatocellular carcinoma von Esteban-Fabró, Roger, Willoughby, Catherine E., Piqué-Gili, Marta, Peix, Judit, Montironi, Carla, Abril-Fornaguera, Jordi, Torrens, Laura, Pinyol, Roser, Llovet, Josep M.

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Immunomodulatory effects of lenvatinib plus anti-PD1 in mice and rationale for patient enrichment in hepatocellular carcinoma von Torrens, Laura, Montironi, Carla, Puigvehí, Marc, Mesropian, Agavni, Leslie, Jack, Haber, Philipp K, Maeda, Miho, Balaseviciute, Ugne, Willoughby, Catherine E, Abril Fornaguera, Jordi, Piqué Gili, Marta, Torres Martín, Miguel, Peix, Judit, Geh, Daniel, Ramon Gil, Erik, Saberi, Behnam, Friedman, Scott L, Mann, Derek A, Sia, Daniela, Llovet i Bayer, Josep Maria

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Immunomodulatory effects of lenvatinib plus anti-programmed cell death protein 1 in mice and rationale for patient enrichment in hepatocellular carcinoma von Torrens, Laura, Montironi, Carla, Puigvehí, Marc, Mesropian, Agavni, Leslie, Jack, Haber, Philipp K, Maeda, Miho, Balaseviciute, Ugne, Willoughby, Catherine E, Abril-Fornaguera, Jordi, Piqué-Gili, Marta, Torres-Martín, Miguel, Peix, Judit, Geh, Daniel, Ramon-Gil, Erik, Saberi, Behnam, Friedman, Scott L, Mann, Derek A, Sia, Daniela, Llovet, Josep Maria

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Corrigendum to ‘Molecular characterisation of hepatocellular carcinoma in patients with non-alcoholic steatohepatitis’ [J Hepatol 75 (2021) 865–878] von Pinyol, Roser, Torrecilla, Sara, Wang, Huan, Montironi, Carla, Piqué-Gili, Marta, Torres-Martin, Miguel, Wei-Qiang, Leow, Willoughby, Catherine E., Ramadori, Pierluigi, Andreu-Oller, Carmen, Taik, Patricia, Lee, Youngmin A., Moeini, Agrin, Peix, Judit, Faure-Dupuy, Suzanne, Riedl, Tobias, Schuehle, Svenja, Oliveira, Claudia P., Alves, Venancio A., Boffetta, Paolo, Lachenmayer, Anja, Roessler, Stephanie, Minguez, Beatriz, Schirmacher, Peter, Dufour, Jean-François, Thung, Swan N., Reeves, Helen L., Carrilho, Flair J., Chang, Charissa, Uzilov, Andrew V., Heikenwalder, Mathias, Sanyal, Arun, Friedman, Scott L., Sia, Daniela, Llovet, Josep M.

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Molecular characterization of hepatocellular carcinoma in patients with nonalcoholic steatohepatitis von Pinyol, Roser, Torrecilla, Sara, Wang, Huan, Montironi, Carla, Piqué Gili, Marta, Torres Martín, Miguel, Wei-Qiang, Leow, Willoughby, Catherine E, Ramadori, Pierluigi, Andreu Oller, Carmen, Taik, Patricia, Lee, Youngmin A, Moeini, Agrin, Peix, Judit, Faure-Dupuy, Suzanne, Riedl, Tobias, Schuehle, Svenja, Oliveira, Claudia P, Alves, Venancio A, Boffetta, Paolo, Lachenmayer, Anja, Roessler, Sthephanie, Minguez, Beatriz, Schirmacher, Peter, Dufour, Jean-François, Thung, Swan N, Reeves, Helen L, Carrilho, Flair J, Chang, Charissa, Uzilov, Andrew V, Heikenwälder, Mathias, Sanyal, Arun, Friedman, Scott L, Sia, Daniela, Llovet i Bayer, Josep Maria

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Abstract PR02: PMEPA1 has an oncogenic role in the context of TGF-β signaling in hepatocellular carcinoma von Piqué-Gili, Marta, Andreu-Oller, Carmen, Pinyol, Roser, Esteban, Roger, Bárcena-Varela, Marina, Peix, Judit, Abril-Fornaguera, Jordi, Lindblad, Katherine E., Torres-Martin, Miguel, Huguet-Pradell, Júlia, Sia, Daniela, Lujambio, Amaia, Llovet, Josep M

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Abstract 840: PMEPA1 is an oncogene linked to TGF-β signaling in hepatocellular carcinoma von Piqué-Gili, Marta, Andreu-Oller, Carmen, Pinyol, Roser, Bárcena-Varela, Marina, Esteban-Fabró, Roger, Peix, Judit, Abril-Fornaguera, Jordi, Lindblad, Katherine E., Torres-Martin, Miguel, Sia, Daniela, Lujambio, Amaia, Llovet, Josep M.

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