Role of ghrelin isoforms in the mitigation of hepatic inflammation, mitochondrial dysfunction, and endoplasmic reticulum stress after bariatric surgery in rats von Ezquerro, S., Becerril, S., Tuero, C., Méndez-Giménez, L., Mocha, F., Moncada, R., Valentí, V., Cienfuegos, J. A., Catalán, V., Gómez-Ambrosi, J., Piper Hanley, K., Frühbeck, G., Rodríguez, A.

Volltext

P621 INTEGREN β1 REGULATES HEPATIC STELLATE CELL ACTIVATION VIA THE ACTIN MYOSIN CYTOSKELETON von Martin, K, Pritchett, J, Harvey, E, Athwal, V, Llewellyn, J, Streuli, C, Zeef, L, Hanley, N, Piper Hanley, K

Volltext

P617 MECHANOSENSITIVE SIGNALLING VIA Yap/Taz DURING HEPATIC STELLATE CELL ACTIVATION von Pritchett, J.P, Martin, K, Llewellyn, J, Henderson, D, Athwal, V, Hanley, N, Piper Hanley, K

Volltext

1123 UNDERSTANDING INTEGRIN SIGNALLING DURING LIVER FIBROSIS PROVIDES INSIGHT INTO THEIR MODULATION AS A THERAPEUTIC STRATEGY TO TREAT THE DISEASE von Martin, K, Pritchett, J, Harvey, E, Athwal, V, Streuli, C, Hanley, N, Piper Hanley, K

Volltext

P271 Proof of concept pilot study to assess the utility of magnetic resonance extra-cellular volume quantification to diagnose advanced liver disease in people with cystic fibrosis von Tewkesbury, D., Scott, J., Bright-Thomas, R., Liong, S., Naish, J., Piper-Hanley, K., Rudralingam, V., Athwal, V., Jones, A.

Volltext

Effects of sleep disturbance on dyspnoea and impaired lung function following hospital admission due to COVID-19 in the UK: a prospective multicentre cohort study von Houchen-Wolloff, Linzy, Jolley, Caroline J, Leavy, Olivia C, Piper-Hanley, Karen, Saunders, Ruth M, Cunningham, P S, Chalder, T, Donaldson, G, Edwardson, C L, Greening, N J, Jolley, C J, McAuley, H J C, Thorpe, M, Amoils, S, Aslani, S, Avram, C, Bailey, L, Barrett, F, Basire, D, Beggs, M, Bourne, C, Brown, A, Channon, K M, Charalambou, A, Chilvers, E R, Chong-James, K, Chrystal, M, Cooper, B, Cooper, J, Cooper, S, Craig, T, Cruz, I, Dempsey, K, Djukanovic, R, Evans, J, Finch, J, Francis, S, Frankel, A, French, N, Hardy, E, Hardy, T, Hockridge, J, Howard, K, Hufton, E, Hussell, T, Ilyas, F, Ingham, J, Jones, H, Kirk, J, Langenberg, C, Mariveles, M, Maskell, N, McArdle, A, McCormick, J, McCourt, P, McGinness, J, McNarry, M, Mehta, P, Menzies, D, Moss, P, Needham, R, Neill, P, Neubauer, S, Novotny, P, Openshaw, P J M, Owen, J, Price, D, Propescu, J, Qureshi, I N, Rees, M, Regan, K, Ribeiro, C, Ross, G, Sabit, R, Samakomva, T, Samuel, R, Sapey, E, Selby, N, Semple, M G, Short, J, Smith, L, Stringer, E, Summersgill, C, Tench, H, Thomas-Woods, T, Tomlinson, J, Tripp, K A, Turner, S, Turney, S, Wallis, T, Weir McCall, J, Whitehead, V, Whittaker, S, Williams, J, Williams-Howard, S A, Wood, C, Wraith, D, Xu, M, Zhao, B, Zheng, B

Volltext

P309 FibroScan improves diagnosis of Cystic Fibrosis-Related Liver Disease von Scott, J., Jokl, E., Pritchett, J., Piper-Hanley, K., Barry, P., Athwal, V., Jones, A.

Volltext

Effects of sleep disturbance on dyspnoea and impaired lung function following hospital admission due to COVID-19 in the UK: a prospective multicentre cohort study von Jackson, C, Stewart, ID, Plekhanova, T, Cunningham, PS, Hazel, AL, Al-Sheklly, B, Aul, R, Bolton, CE, Chalder, T, Chalmers, JD, Chaudhuri, N, Docherty, AB, Donaldson, G, Edwardson, CL, Elneima, O, Greening, NJ, Hanley, NA, Harris, VC, Harrison, EM, Ho, L-P, Houchen-Wolloff, L, Howard, LS, Jolley, CJ, Jones, MG, Leavy, OC, Lewis, KE, Lone, NI, Marks, M, McAuley, HJC, McNarry, MA, Patel, BV, Piper-Hanley, K, Poinasamy, K, Raman, B, Richardson, M, Rivera-Ortega, P, Rowland-Jones, SL, Rowlands, AV, Saunders, RM, Scott, JT, Sereno, M, Shah, AM, Shikotra, A, Singapuri, A, Stanel, SC, Thorpe, M, Wootton, DG, Yates, T, Gisli Jenkins, R, Singh, SJ, Man, WD-C, Brightling, CE, Wain, LV, Porter, JC, Thompson, AAR, Horsley, A, Molyneaux, PL, Evans, RA, Jones, SE, Rutter, MK, Blaikley, JF, PHOSP-COVID Study Collaborative Group

Volltext

Understanding the burden of interstitial lung disease post-COVID-19: the UK Interstitial Lung Disease-Long COVID Study (UKILD-Long COVID) von Wild, JM, Porter, JC, Molyneaux, PL, George, PM, Stewart, I, Allen, RJ, Aul, R, Baillie, JK, Barratt, SL, Beirne, P, Bianchi, SM, Blaikley, JF, Brooke, J, Chaudhuri, N, Collier, G, Denneny, EK, Docherty, A, Fabbri, L, Gibbons, MA, Gleeson, F, Gooptu, B, Hall, IP, Hanley, NA, Heightman, M, Hillman, TE, Johnson, SR, Jones, MG, Khan, F, Lawson, R, Mehta, P, Mitchell, JA, Plate, M, Poinasamy, K, Quint, JK, Rivera-Ortega, P, Semple, M, Simpson, AJ, Smith, DJF, Spears, M, Spencer, LG, Stanel, SC, Thickett, DR, Thompson, AAR, Walsh, SLF, Weatherley, ND, Weeks, ME, Wootton, DG, Brightling, CE, Chambers, RC, Ho, L-P, Jacob, J, Piper Hanley, K, Wain, L, Jenkins, RG

Volltext

OC-028 Identification of SOX9 as a novel mechanism to explain aspects of liver fibrosis von Pritchett, J, Athwal, V S, Harvey, E, Oakley, F, Mann, D A, Hanley, N, Piper-Hanley, K

Volltext

104 SOX9 IS A CRITICAL REGULATOR OF EXTRACELLULAR MATRIX DEPOSITION DURING LIVER FIBROSIS von Pritchett, J, Athwal, V, Harvey, E, Oakley, F, Mann, D, Hanley, N, Hanley, K. Piper

Volltext

Residual lung abnormalities following COVID-19 hospitalization: interim analysis of the UKILD post-COVID study von Stewart, I, Jacob, J, George, PM, Molyneaux, PL, Porter, JC, Allen, RJ, Aslani, S, Baillie, JK, Barratt, SL, Beirne, P, Bianchi, SM, Blaikley, JF, Chalmers, JD, Chambers, RC, Chaudhuri, N, Coleman, C, Collier, G, Denneny, EK, Docherty, A, Elneima, O, Evans, RA, Fabbri, L, Gibbons, MA, Gleeson, FV, Gooptu, B, Greening, NJ, Guillen Guio, B, Hall, IP, Hanley, NA, Harris, V, Harrison, EM, Heightman, M, Hillman, TE, Horsley, A, Houchen-Wolloff, L, Jarrold, I, Johnson, SR, Jones, MG, Khan, F, Lawson, R, Leavy, O, Lone, N, Marks, M, McAuley, H, Mehta, P, Parekh, D, Piper Hanley, K, Platé, M, Pearl, J, Poinasamy, K, Quint, JK, Raman, B, Richardson, M, Rivera-Ortega, P, Saunders, L, Saunders, R, Semple, MG, Sereno, M, Shikotra, A, Simpson, AJ, Singapuri, A, Smith, DJ, Spears, M, Spencer, LG, Stanel, S, Thickett, D, Thompson, AAR, Thorpe, M, Walsh, SL, Walker, S, Weatherley, ND, Weeks, M, Wild, JM, Wootton, DG, Brightling, CE, Ho, L-P, Wain, LV, Jenkins, RG

Volltext bestellen

Understanding the burden of interstitial lung disease post-COVID-19: the UK Interstitial Lung Disease-Long COVID Study (UKILD-Long COVID) von Wild, JM, Porter, JC, Molyneaux, PL, George, PM, Stewart, I, Allen, RJ, Aul, R, Baillie, JK, Barratt, SL, Beirne, P, Bianchi, SM, Blaikley, JF, Brooke, J, Chaudhuri, N, Collier, G, Denneny, EK, Docherty, A, Fabbri, L, Gibbons, MA, Gleeson, FV, Gooptu, B, Hall, IP, Hanley, NA, Heightman, M, Hillman, TE, Johnson, SR, Jones, MG, Khan, F, Lawson, R, Mehta, P, Mitchell, JA, Platé, M, Poinasamy, K, Quint, JK, Rivera-Ortega, P, Semple, M, Simpson, AJ, Smith, DJF, Spears, M, Spencer, LG, Stanel, SC, Thickett, DR, Thompson, AAR, Walsh, SLF, Weatherley, ND, Weeks, ME, Wootton, DG, Brightling, CE, Chambers, RC, Ho, LP, Jacob, J, Piper Hanley, K, Wain, LV, Jenkins, RG

Volltext bestellen

Understanding the burden of interstitial lung disease post-COVID-19: the UK Interstitial Lung Disease-Long COVID Study (UKILD-Long COVID) von Wild, JM, Porter, JC, Molyneaux, PL, George, PM, Stewart, I, Allen, RJ, Aul, R, Baillie, JK, Barratt, SL, Beirne, P, Bianchi, SM, Blaikley, JF, Brooke, J, Chaudhuri, N, Collier, G, Denneny, EK, Docherty, A, Fabbri, L, Gibbons, MA, Gleeson, FV, Gooptu, B, Hall, IP, Hanley, NA, Heightman, M, Hillman, TE, Johnson, SR, Jones, MG, Khan, F, Lawson, R, Mehta, P, Mitchell, JA, Platé, M, Poinasamy, K, Quint, JK, Rivera-Ortega, P, Semple, M, Simpson, AJ, Smith, D, Spears, M, Spencer, LG, Stanel, SC, Thickett, DR, Thompson, AAR, Walsh, SL, Weatherley, ND, Weeks, ME, Wootton, DG, Brightling, CE, Chambers, RC, Ho, L-P, Jacob, J, Piper Hanley, K, Wain, LV, Jenkins, RG

Volltext bestellen

The circadian clock protein REVERBα inhibits pulmonary fibrosis development von Cunningham, PS, Meijer, P, Nazgiewicz, A, Anderson, SG, Borthwick, LA, Bagnall, J, Kitchen, GB, Lodyga, M, Begley, N, Venkateswaran, RV, Shah, R, Mercer, PF, Durrington, HJ, Henderson, NC, Piper-Hanley, K, Fisher, AJ, Chambers, RC, Bechtold, DA, Gibbs, JE, Loudon, AS, Rutter, MK, Hinz, B, Ray, DW, Blaikley, JF

Volltext bestellen

Human notochordal cell transcriptome unveils potential regulators of cell function in the developing intervertebral disc von Rodrigues-Pinto, Ricardo, Ward, Lizzy, Humphreys, Matthew, Zeef, Leo A. H., Berry, Andrew, Hanley, Karen Piper, Hanley, Neil, Richardson, Stephen M., Hoyland, Judith A.

Volltext

In humans, early cortisol biosynthesis provides a mechanism to safeguard female sexual development von Goto, Masahiro, Piper Hanley, Karen, Marcos, Josep, Wood, Peter J, Wright, Sarah, Postle, Anthony D, Cameron, Iain T, Mason, J Ian, Wilson, David I, Hanley, Neil A

Volltext

Monocyte migration profiles define disease severity in acute COVID-19 and unique features of long COVID von Scott, Nicholas A, Pearmain, Laurence, Knight, Sean B, Brand, Oliver, Morgan, David J, Jagger, Christopher, Harbach, Sarah, Khan, Saba, Shuwa, Halima A, Franklin, Miriam, Kästele, Verena, Williams, Thomas, Prise, Ian, McClure, Flora A, Hackney, Pamela, Smith, Lara, Menon, Madhvi, Konkel, Joanne E, Lawless, Criag, Wilson, James, Mathioudakis, Alexander G, Stanel, Stefan C, Ustianowski, Andrew, Lindergard, Gabriella, Brij, Seema, Diar Bakerly, Nawar, Dark, Paul, Brightling, Christopher, Rivera-Ortega, Pilar, Lord, Graham M, Horsley, Alex, Piper Hanley, Karen, Felton, Timothy, Simpson, Angela, Grainger, John R, Hussell, Tracy, Mann, Elizabeth R

Volltext

Beta cell differentiation during early human pancreas development von Piper, K, Brickwood, S, Turnpenny, LW, Cameron, IT, Ball, SG, Wilson, DI, Hanley, NA

Volltext

Effects of sleep disturbance on dyspnoea and impaired lung function following hospital admission due to COVID-19 in the UK: a prospective multicentre cohort study von Jackson, Callum, Hazel, Andrew, Al-Sheklly, Bashar, Hanley, Neil, Piper Hanley, Karen, Stanel, Stefan, Horsley, Alexander, Rutter, Martin K, Blaikley, John, et al, Dark, Paul

Volltext