Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain von Lintner, Nathanael G, McClure, Kim F, Petersen, Donna, Londregan, Allyn T, Piotrowski, David W, Wei, Liuqing, Xiao, Jun, Bolt, Michael, Loria, Paula M, Maguire, Bruce, Geoghegan, Kieran F, Huang, Austin, Rolph, Tim, Liras, Spiros, Doudna, Jennifer A, Dullea, Robert G, Cate, Jamie H D

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Deuterium isotope effects in drug pharmacokinetics II: Substrate-dependence of the reaction mechanism influences outcome for cytochrome P450 cleared drugs von Sun, Hao, Piotrowski, David W, Orr, Suvi T M, Warmus, Joseph S, Wolford, Angela C, Coffey, Steven B, Futatsugi, Kentaro, Zhang, Yinsheng, Vaz, Alfin D N

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Mineralocorticoid receptor antagonists for the treatment of hypertension and diabetic nephropathy von Piotrowski, David W

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Mineralocorticoid Receptor Antagonists for the Treatment of Hypertension and Diabetic Nephropathy: Miniperspective von Piotrowski, David W

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Acylative Dynamic Kinetic Resolution of Secondary Alcohols: Tandem Catalysis by HyperBTM and Bäckvall's Ruthenium Complex von Kinens, Artis, Balkaitis, Simonas, Ahmad, Omar K, Piotrowski, David W, Suna, Edgars

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Expanding Reactivity in DNA-Encoded Library Synthesis via Reversible Binding of DNA to an Inert Quaternary Ammonium Support von Flood, Dillon T, Asai, Shota, Zhang, Xuejing, Wang, Jie, Yoon, Leonard, Adams, Zoë C, Dillingham, Blythe C, Sanchez, Brittany B, Vantourout, Julien C, Flanagan, Mark E, Piotrowski, David W, Richardson, Paul, Green, Samantha A, Shenvi, Ryan A, Chen, Jason S, Baran, Phil S, Dawson, Philip E

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A Small-Molecule Oral Agonist of the Human Glucagon-like Peptide‑1 Receptor von Griffith, David A., Edmonds, David J., Fortin, Jean-Philippe, Kalgutkar, Amit S., Kuzmiski, J. Brent, Loria, Paula M., Saxena, Aditi R., Bagley, Scott W., Buckeridge, Clare, Curto, John M., Derksen, David R., Dias, João M., Griffor, Matthew C., Han, Seungil, Jackson, V. Margaret, Landis, Margaret S., Lettiere, Daniel, Limberakis, Chris, Liu, Yuhang, Mathiowetz, Alan M., Patel, Jayesh C., Piotrowski, David W., Price, David A., Ruggeri, Roger B., Tess, David A.

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Cycloisomerization of Olefins in Water von Matos, Jeishla L. M., Green, Samantha A., Chun, Yuge, Dang, Vuong Q., Dushin, Russell G., Richardson, Paul, Chen, Jason S., Piotrowski, David W., Paegel, Brian M., Shenvi, Ryan A.

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Development of a Chiral DMAP Catalyst for the Dynamic Kinetic Resolution of Azole Hemiaminals von Kinens, Artis, Sejejs, Marcis, Kamlet, Adam S, Piotrowski, David W, Vedejs, Edwin, Suna, Edgars

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Regio- and Enantioselective Synthesis of Azole Hemiaminal Esters by Lewis Base Catalyzed Dynamic Kinetic Resolution von Piotrowski, David W, Kamlet, Adam S, Dechert-Schmitt, Anne-Marie R, Yan, Jiangli, Brandt, Thomas A, Xiao, Jun, Wei, Liuqing, Barrila, Mark T

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Merging C(sp)-H activation with DNA-encoding von Fan, Zhoulong, Zhao, Shuai, Liu, Tao, Shen, Peng-Xiang, Cui, Zi-Ning, Zhuang, Zhe, Shao, Qian, Chen, Jason S, Ratnayake, Anokha S, Flanagan, Mark E, Kölmel, Dominik K, Piotrowski, David W, Richardson, Paul, Yu, Jin-Quan

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RASS‐Enabled S/P−C and S−N Bond Formation for DEL Synthesis von Flood, Dillon T., Zhang, Xuejing, Fu, Xiang, Zhao, Zhenxiang, Asai, Shota, Sanchez, Brittany B., Sturgell, Emily J., Vantourout, Julien C., Richardson, Paul, Flanagan, Mark E., Piotrowski, David W., Kölmel, Dominik K., Wan, Jinqiao, Tsai, Mei‐Hsuan, Chen, Jason S., Baran, Phil S., Dawson, Philip E.

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6-Azaspiro[2.5]octanes as small molecule agonists of the human glucagon-like peptide-1 receptor von Aspnes, Gary E., Bagley, Scott W., Coffey, Steven B., Conn, Edward L., Curto, John M., Edmonds, David J., Genovino, Julien, Griffith, David A., Ingle, Gajendra, Jiao, Wenhua, Limberakis, Chris, Mathiowetz, Alan M., Piotrowski, David W., Rose, Colin R., Ruggeri, Roger B., Wei, Liuqing

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The use of plasma aldosterone and urinary sodium to potassium ratio as translatable quantitative biomarkers of mineralocorticoid receptor antagonism von Eudy, Rena J, Sahasrabudhe, Vaishali, Sweeney, Kevin, Tugnait, Meera, King-Ahmad, Amanda, Near, Kristen, Loria, Paula, Banker, Mary Ellen, Piotrowski, David W, Boustany-Kari, Carine M

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Enantioselective synthesis of 1,2,4-triazolines catalyzed by a cinchona alkaloid-derived organocatalyst von Shao, Qian, Chen, Jiean, Tu, Meihua, Piotrowski, David W, Huang, Yong

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Small Molecule Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitors: Hit to Lead Optimization of Systemic Agents von Londregan, Allyn T, Wei, Liuqing, Xiao, Jun, Lintner, Nathanael G, Petersen, Donna, Dullea, Robert G, McClure, Kim F, Bolt, Michael W, Warmus, Joseph S, Coffey, Steven B, Limberakis, Chris, Genovino, Julien, Thuma, Benjamin A, Hesp, Kevin D, Aspnes, Gary E, Reidich, Benjamin, Salatto, Christopher T, Chabot, Jeffrey R, Cate, Jamie H. D, Liras, Spiros, Piotrowski, David W

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Small molecule inhibitors of PCSK9. SAR investigations of head and amine groups von Aspnes, Gary E., Coffey, Steven B., Darout, Etzer, Dechert-Schmitt, Anne-Marie, Dullea, Robert G., Kamlet, Adam S., Limberakis, Chris, Londregan, Allyn T., McClure, Kim F., Menhaji-Klotz, Elnaz, Piotrowski, David W., Polivkova, Jana, Raymer, Brian, Ruggeri, Roger B., Salatto, Christopher T., Tu, Meihua, Wei, Liuqing, Xiao, Jun

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PF-07059013: A Noncovalent Modulator of Hemoglobin for Treatment of Sickle Cell Disease von Gopalsamy, Ariamala, Aulabaugh, Ann E, Barakat, Amey, Beaumont, Kevin C, Cabral, Shawn, Canterbury, Daniel P, Casimiro-Garcia, Agustin, Chang, Jeanne S, Chen, Ming Z, Choi, Chulho, Dow, Robert L, Fadeyi, Olugbeminiyi O, Feng, Xidong, France, Scott P, Howard, Roger M, Janz, Jay M, Jasti, Jayasankar, Jasuja, Reema, Jones, Lyn H, King-Ahmad, Amanda, Knee, Kelly M, Kohrt, Jeffrey T, Limberakis, Chris, Liras, Spiros, Martinez, Carlos A, McClure, Kim F, Narayanan, Arjun, Narula, Jatin, Novak, Jonathan J, O'Connell, Thomas N, Parikh, Mihir D, Piotrowski, David W, Plotnikova, Olga, Robinson, Ralph P, Sahasrabudhe, Parag V, Sharma, Raman, Thuma, Benjamin A, Vasa, Dipy, Wei, Liuqing, Wenzel, A Zane, Withka, Jane M, Xiao, Jun, Yayla, Hatice G

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Positive Allosteric Modulators of the α7 Nicotinic Acetylcholine Receptor: SAR Investigation Around PNU-120596 von Acker, Brad A, Badescu, Valentina O, Berkenpas, Mitchell B, Groppi, Vincent E, Hajós, Mihaly, Higdon, Nicole R, Hurst, Raymond S, Jon Jacobsen, E, Margolis, Brandon J, McWhorter, William W, Myers, Jason K, Piotrowski, David W, Rogers, Bruce N, Sarapa, Dusan, Vetman, Tatiana N, Walker, Daniel P, Wall, Theron M, Wilhite, David M, Wishka, Donn G, Xu, Wenjian, Yates, Karen M

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Liver‐Targeted Small‐Molecule Inhibitors of Proprotein Convertase Subtilisin/Kexin Type 9 Synthesis von McClure, Kim F., Piotrowski, David W., Petersen, Donna, Wei, Liuqing, Xiao, Jun, Londregan, Allyn T., Kamlet, Adam S., Dechert‐Schmitt, Anne‐Marie, Raymer, Brian, Ruggeri, Roger B., Canterbury, Daniel, Limberakis, Chris, Liras, Spiros, DaSilva‐Jardine, Paul, Dullea, Robert G., Loria, Paula M., Reidich, Benjamin, Salatto, Christopher T., Eng, Heather, Kimoto, Emi, Atkinson, Karen, King‐Ahmad, Amanda, Scott, Dennis, Beaumont, Kevin, Chabot, Jeffrey R., Bolt, Michael W., Maresca, Kevin, Dahl, Kenneth, Arakawa, Ryosuke, Takano, Akihiro, Halldin, Christer

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