The yeast protein kinase Sch9 adjusts V-ATPase assembly/disassembly to control pH homeostasis and longevity in response to glucose availability von Wilms, Tobias, Swinnen, Erwin, Eskes, Elja, Dolz-Edo, Laura, Uwineza, Alice, Van Essche, Ruben, Rosseels, Joëlle, Zabrocki, Piotr, Cameroni, Elisabetta, Franssens, Vanessa, De Virgilio, Claudio, Smits, Gertien J, Winderickx, Joris

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Upregulation of MAPK Negative Feedback Regulators and RET in Mutant ALK Neuroblastoma: Implications for Targeted Treatment von Lambertz, Irina, Kumps, Candy, Claeys, Shana, Lindner, Sven, Beckers, Anneleen, Janssens, Els, Carter, Daniel R, Cazes, Alex, Cheung, Belamy B, De Mariano, Marilena, De Bondt, An, De Brouwer, Sara, Delattre, Olivier, Gibbons, Jay, Janoueix-Lerosey, Isabelle, Laureys, Geneviève, Liang, Chris, Marchall, Glenn M, Porcu, Michael, Takita, Junko, Trujillo, David Camacho, Van Den Wyngaert, Ilse, Van Roy, Nadine, Van Goethem, Alan, Van Maerken, Tom, Zabrocki, Piotr, Cools, Jan, Schulte, Johannes H, Vialard, Jorge, Speleman, Frank, De Preter, Katleen

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Monotherapy With Anti-CD70 Antibody Causes Long-Term Mouse Cardiac Allograft Acceptance With Induction of Tolerogenic Dendritic Cells von Zhao, Jing, Que, Weitao, Du, Xiaoxiao, Fujino, Masayuki, Ichimaru, Naotsugu, Ueta, Hisashi, Tokuda, Nobuko, Guo, Wen-zhi, Zabrocki, Piotr, de Haard, Hans, Nonomura, Norio, Li, Xiao-Kang

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P317: ANTI‐LEUKEMIA ACTIVITY OF CD70‐DIRECTED IMMUNOTHERAPY IN B CELL PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA von Sun, Qian, Zabrocki, Piotr, Seyfried, Felix, Haard, Hans, Kronnie, Geertruyte, Debatin, Klaus‐Michael, Hinrich Meyer, Lüder

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Anti-CD70 Monoclonal Antibodies Show Efficacy in Preclinical Models for Chronic Lymphoblastic Leukemia von Chen, Shih-Shih, Yan, Xiao-Jie, Van Rompaey, Luc, Zabrocki, Piotr, Chiorazzi, Nicholas

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Cusatuzumab for treatment of CD70‐positive relapsed or refractory cutaneous T‐cell lymphoma von Leupin, Nicolas, Zinzani, Pier Luigi, Morschhauser, Franck, Dalle, Stéphane, Maerevoet, Marie, Michot, Jean‐Marie, Ribrag, Vincent, Offner, Fritz, Beylot‐Barry, Marie, Moins‐Teisserenc, Hélène, Zwaenepoel, Karen, Winne, Koen, Battistella, Maxime, Hultberg, Anna, Gandini, Domenica, Moshir, Mahan, Jacobs, Julie, Delahaye, Tim, Khan, Aitzaz, Zabrocki, Piotr, Silence, Karen, Rompaey, Luc, Borg, Christophe, Motta, Giovanna, Melle, Federica, Calleri, Angelica, Pauwels, Patrick, Haard, Hans, Pileri, Stefano, Bagot, Martine

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Meta-analysis of Neuroblastomas Reveals a Skewed ALK Mutation Spectrum in Tumors with MYCN Amplification von DE BROUWER, Sara, DE PETER, Katleen, DE PAEPE, Anne, LAUREYS, Geneviève, SCHULTE, Johannes H, SCHRAMM, Alexander, VAN DEN BROECKE, Caroline, VERMEULEN, Joëlle, VAN ROY, Nadine, BEISKE, Klaus, RENARD, Marleen, NOGUERA, Rosa, KUMPS, Candy, DELATTRE, Olivier, JANOUEIX-LEROSEY, Isabelle, KOGNER, Per, MARTINSSON, Tommy, NAKAGAWARA, Akira, OHIRA, Miki, CARON, Huib, EGGERT, Angelika, COOLS, Jan, VERSTEEG, Rogier, ZABROCKI, Piotr, SPELEMAN, Frank, PORCU, Michaël, WESTERHOUT, Ellen M, LAKEMAN, Arjan, VANDESOMPELE, Jo, HOEBEECK, Jasmien, VAN MAERKEN, Tom

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Protein folding diseases and neurodegeneration: Lessons learned from yeast von Winderickx, Joris, Delay, Charlotte, De Vos, Ann, Klinger, Harald, Pellens, Klaartje, Vanhelmont, Thomas, Van Leuven, Fred, Zabrocki, Piotr

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Functional Mitochondria Are Required for α-Synuclein Toxicity in Aging Yeast von Büttner, Sabrina, Bitto, Alessandro, Ring, Julia, Augsten, Manuela, Zabrocki, Piotr, Eisenberg, Tobias, Jungwirth, Helmut, Hutter, Sylvia, Carmona-Gutierrez, Didac, Kroemer, Guido, Winderickx, Joris, Madeo, Frank

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Screening a Broad Range of Solid and Haematological Tumour Types for CD70 Expression Using a Uniform IHC Methodology as Potential Patient Stratification Method von Flieswasser, Tal, Camara-Clayette, Valérie, Danu, Alina, Bosq, Jacques, Ribrag, Vincent, Zabrocki, Piotr, Van Rompaey, Luc, de Haard, Hans, Zwaenepoel, Karen, Smits, Evelien, Pauwels, Patrick, Jacobs, Julie

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Phosphorylation, lipid raft interaction and traffic of α-synuclein in a yeast model for Parkinson von Zabrocki, Piotr, Bastiaens, Ilse, Delay, Charlotte, Bammens, Tine, Ghillebert, Ruben, Pellens, Klaartje, De Virgilio, Claudio, Van Leuven, Fred, Winderickx, Joris

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FLT1 kinase is a mediator of radioresistance and survival in head and neck squamous cell carcinoma von Van Limbergen, Evert Jan, Zabrocki, Piotr, Porcu, Michaël, Hauben, Esther, Cools, Jan, Nuyts, Sandra

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The yeast protein kinase Sch9 adjusts V-ATPase assembly/disassembly to control pH homeostasis and longevity in response to glucose availability von Wilms, Tobias, Swinnen, Erwin, Eskes, Elja, Dolz-Edo, Laura, Uwineza, Alice, Van Essche, Ruben, Rosseels, Joelle, Zabrocki, Piotr, Cameroni, Elisabetta, Franssens, Vanessa, De Virgilio, Claudio, Smits, Gertien J, Winderickx, Joris

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Argx-110 for Treatment of CD70-Positive Advanced Cutaneous T-Cell Lymphoma in a Phase 1/2 Clinical Trial von Bagot, Martine, Maerevoet, Marie, Zinzani, Pier Luigi, Offner, Fritz, Morschhauser, Franck, Michot, Jean-Marie, Ribrag, Vincent, Battistella, Maxime, Moins, Helene, Calleri, Angelica, Dalle, Stéphane, Beylot-Barry, Marie, Zwaenepoel, Karen, De Winnie, Koen, Marie-Cardine, Anne, Cayuela, Jean-Michel, Tabanelli, Valentina, Motta, Giovanna, Melle, Federica, Hultberg, Anna, Gandini, Domenica, Marafioti, Teresa, Moshir, Mahan, Delahaye, Tim, Zabrocki, Piotr, Silence, Karen, Van Rompaey, Luc, Bensussan, Armand, De Haard, Hans, Pauwels, Patrick, Leupin, Nicolas, Pileri, Stefano A.

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Mitochondrial dysfunction leads to reduced chronological lifespan and increased apoptosis in yeast von Aerts, An M., Zabrocki, Piotr, Govaert, Gilmer, Mathys, Janick, Carmona-Gutierrez, Didac, Madeo, Frank, Winderickx, Joris, Cammue, Bruno P.A., Thevissen, Karin

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Characterization of α‐synuclein aggregation and synergistic toxicity with protein tau in yeast von Zabrocki, Piotr, Pellens, Klaartje, Vanhelmont, Thomas, Vandebroek, Tom, Griffioen, Gerard, Wera, Stefaan, Van Leuven, Fred, Winderickx, Joris

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A yeast-based model of α-synucleinopathy identifies compounds with therapeutic potential von Griffioen, Gerard, Duhamel, Hein, Van Damme, Nele, Pellens, Klaartje, Zabrocki, Piotr, Pannecouque, Christophe, van Leuven, Fred, Winderickx, Joris, Wera, Stefaan

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Upregulation of MAPK Negative Feedback Regulators and RET in Mutant ALK Neuroblastoma: Implications for Targeted Treatment von Lambertz, Irina, Kumps, Candy, Claeys, Shana, Lindner, Sven, Beckers, Anneleen, Janssens, Els, Carter, Daniel R, Cazes, Alex, Cheung, Belamy B, De Mariano, Marilena, De Bondt, An, De Brouwer, Sara, Delattre, Olivier, Gibbons, Jay, Janoueix-Lerosey, Isabelle, Laureys, Geneviève, Liang, Chris, Marchall, Glenn M, Porcu, Michael, Takita, Junko, Trujillo, David Camacho, Van Den Wyngaert, Ilse, Van Roy, Nadine, Van Goethem, Alan, Van Maerken, Tom, Zabrocki, Piotr, Cools, Jan, Schulte, Johannes H, Vialard, Jorge, Speleman, Frank, De Preter, Katleen

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P4‐032: Genetic screening for components mediating α‐synuclein toxicity in a humanized yeast model system von Franssens, Vanessa D.L., Zabrocki, Piotr, De Vos, Ann, Delay, Charlotte, Bammens, Tine, Vanhelmont, Thomas, Van Leuven, Fred, Winderickx, Joris

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Functional Mitochondria Are Required for α-Synuclein Toxicity in Aging Yeast von Sabrina Büttner, Alessandro Bitto, Julia Ring, Manuela Augsten, Piotr Zabrocki, Tobias Eisenberg, Helmut Jungwirth, Sylvia Hutter, Didac Carmona-Gutierrez, Guido Kroemer, Joris Winderickx, Frank Madeo

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