Proteome Mapping of the Human Pancreatic Islet Microenvironment Reveals Endocrine–Exocrine Signaling Sphere of Influence von Gosline, Sara J.C., Velickovic, Marija, Pino, James, Day, Le Z., Attah, Isaac K., Swensen, Adam C., Danna, Vincent, Posso, Camilo, Rodland, Karin D., Chen, Jing, Matthews, Clayton E., Campbell-Thompson, Martha, Laskin, Julia, Burnum-Johnson, Kristin, Zhu, Ying, Piehowski, Paul D.

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Activated Oncogenic Pathway Modifies Iron Network in Breast Epithelial Cells: A Dynamic Modeling Perspective von Chifman, Julia, Arat, Seda, Deng, Zhiyong, Lemler, Erica, Pino, James C, Harris, Leonard A, Kochen, Michael A, Lopez, Carlos F, Akman, Steven A, Torti, Frank M, Torti, Suzy V, Laubenbacher, Reinhard

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Evaluation of a pedagogical model for student engagement in learning activities von Pino-James, Nicolás

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CASP11--An Evaluation of a Modular BCL::Fold-Based Protein Structure Prediction Pipeline von Fischer, Axel W, Heinze, Sten, Putnam, Daniel K, Li, Bian, Pino, James C, Xia, Yan, Lopez, Carlos F, Meiler, Jens

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Coupling Microdroplet-Based Sample Preparation, Multiplexed Isobaric Labeling, and Nanoflow Peptide Fractionation for Deep Proteome Profiling of the Tissue Microenvironment von Veličković, Marija, Fillmore, Thomas L., Attah, Isaac Kwame, Posso, Camilo, Pino, James C., Zhao, Rui, Williams, Sarah M., Veličković, Dušan, Jacobs, Jon M., Burnum-Johnson, Kristin E., Zhu, Ying, Piehowski, Paul D.

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Chipper: Open‐source software for semi‐automated segmentation and analysis of birdsong and other natural sounds von Searfoss, Abigail M., Pino, James C., Creanza, Nicole, Zamora‐Gutierrez, Veronica

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GPU-powered model analysis with PySB/cupSODA von Harris, Leonard A, Nobile, Marco S, Pino, James C, Lubbock, Alexander L R, Besozzi, Daniela, Mauri, Giancarlo, Cazzaniga, Paolo, Lopez, Carlos F

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Integrated, High-Throughput, Multiomics Platform Enables Data-Driven Construction of Cellular Responses and Reveals Global Drug Mechanisms of Action von Norris, Jeremy L, Farrow, Melissa A, Gutierrez, Danielle B, Palmer, Lauren D, Muszynski, Nicole, Sherrod, Stacy D, Pino, James C, Allen, Jamie L, Spraggins, Jeffrey M, Lubbock, Alex L. R, Jordan, Ashley, Burns, William, Poland, James C, Romer, Carrie, Manier, M. Lisa, Nei, Yuan-wei, Prentice, Boone M, Rose, Kristie L, Hill, Salisha, Van de Plas, Raf, Tsui, Tina, Braman, Nathaniel M, Keller, M. Ray, Rutherford, Stacey A, Lobdell, Nichole, Lopez, Carlos F, Lacy, D. Borden, McLean, John A, Wikswo, John P, Skaar, Eric P, Caprioli, Richard M

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Signal execution modes emerge in biochemical reaction networks calibrated to experimental data von Ortega, Oscar O., Ozen, Mustafa, Wilson, Blake A., Pino, James C., Irvin, Michael W., Ildefonso, Geena V., Garbett, Shawn P., Lopez, Carlos F.

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Ex vivo to in vivo model of malignant peripheral nerve sheath tumors for precision oncology von Larsson, Alex T, Bhatia, Himanshi, Calizo, Ana, Pollard, Kai, Zhang, Xiaochun, Conniff, Eric, Tibbitts, Justin F, Rono, Elizabeth, Cummins, Katherine, Osum, Sara H, Williams, Kyle B, Crampton, Alexandra L, Jubenville, Tyler, Schefer, Daniel, Yang, Kuangying, Lyu, Yang, Pino, James C, Bade, Jessica, Gross, John M, Lisok, Alla, Dehner, Carina A, Chrisinger, John S A, He, Kevin, Gosline, Sara J C, Pratilas, Christine A, Largaespada, David A, Wood, David K, Hirbe, Angela C

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Processes in DNA damage response from a whole-cell multi-omics perspective von Pino, James C., Lubbock, Alexander L.R., Harris, Leonard A., Gutierrez, Danielle B., Farrow, Melissa A., Muszynski, Nicole, Tsui, Tina, Sherrod, Stacy D., Norris, Jeremy L., McLean, John A., Caprioli, Richard M., Wikswo, John P., Lopez, Carlos F.

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Proteomic and phosphoproteomic measurements enhance ability to predict ex vivo drug response in AML von Gosline, Sara J C, Tognon, Cristina, Nestor, Michael, Joshi, Sunil, Modak, Rucha, Damnernsawad, Alisa, Posso, Camilo, Moon, Jamie, Hansen, Joshua R, Hutchinson-Bunch, Chelsea, Pino, James C, Gritsenko, Marina A, Weitz, Karl K, Traer, Elie, Tyner, Jeffrey, Druker, Brian, Agarwal, Anupriya, Piehowski, Paul, McDermott, Jason E, Rodland, Karin

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CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon RB function in malignant peripheral nerve sheath tumors von Wang, Jiawan, Calizo, Ana, Zhang, Lindy, Pino, James C, Lyu, Yang, Pollard, Kai, Zhang, Xiaochun, Larsson, Alex T, Conniff, Eric, Llosa, Nicolas J, Wood, David K, Largaespada, David A, Moody, Susan E, Gosline, Sara J, Hirbe, Angela C, Pratilas, Christine A

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Interaction analyses of hTAAR1 and mTAAR1 with antagonist EPPTB von Liao, Siyan, Pino, Michael James, Deleon, Catherine, Lindner-Jackson, Maurice, Wu, Chun

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Folding propensity of intrinsically disordered proteins by osmotic stress von Mansouri, Amanda L, Grese, Laura N, Rowe, Erica L, Pino, James C, Chennubhotla, S Chakra, Ramanathan, Arvind, O'Neill, Hugh M, Berthelier, Valerie, Stanley, Christopher B

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Selective Inhibition of JAK1 Primes STAT5-Driven Human Leukemia Cells for ATRA-Induced Differentiation von Ramsey, Haley E., Stengel, Kristy, Pino, James C., Johnston, Gretchen, Childress, Merrida, Gorska, Agnieszka E., Arrate, Pia M., Fuller, Londa, Villaume, Matthew, Fischer, Melissa A., Ferrell, P. Brent, Roe, Caroline E., Zou, Jing, Lubbock, Alexander L. R., Stubbs, Matthew, Zinkel, Sandra, Irish, Jonathan M., Lopez, Carlos F., Hiebert, Scott, Savona, Michael R.

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Mapping the proteogenomic landscape enables prediction of drug response in acute myeloid leukemia von Pino, James C, Posso, Camilo, Joshi, Sunil K, Nestor, Michael, Moon, Jamie, Hansen, Joshua R, Hutchinson-Bunch, Chelsea, Gritsenko, Marina A, Weitz, Karl K, Watanabe-Smith, Kevin, Long, Nicola, McDermott, Jason E, Druker, Brian J, Liu, Tao, Tyner, Jeffrey W, Agarwal, Anupriya, Traer, Elie, Piehowski, Paul D, Tognon, Cristina E, Rodland, Karin D, Gosline, Sara J C

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Probing biased activation of mu-opioid receptor by the biased agonist PZM21 using all atom molecular dynamics simulation von Liao, Siyan, Tan, Kai, Floyd, Cecilia, Bong, Daegun, Pino, Michael James, Wu, Chun

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Modeling drug perturbations at multiple resolutions: Mechanism extraction from multi-omic, multiple timepoint data to single cell mechanistic simulations von Pino, James

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Abstract 3726: INCB52793 JAK1 inhibitor synergizes with ATRA to inhibit expansion of AML von Ramsey, Haley E., Ferrell, P. Brent, Fischer, Melissa A., Gorska, Agnieszka E., Maier, Caroline, Norris, Jeremy, Farrow, Melissa, Guiterrez, Danielle, Pino, James, Zinkel, Sandra, Lopez, Carlos, Koblish, Holly, Stubbs, Matthew, Scherle, Peggy, Irish, Jonathan M., Caprioli, Richard, Savona, Michael R.

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