Boosting NAD+ with a small molecule that activates NAMPT von Gardell, Stephen J., Hopf, Meghan, Khan, Asima, Dispagna, Mauro, Hampton Sessions, E., Falter, Rebecca, Kapoor, Nidhi, Brooks, Jeanne, Culver, Jeffrey, Petucci, Chris, Ma, Chen-Ting, Cohen, Steven E., Tanaka, Jun, Burgos, Emmanuel S., Hirschi, Jennifer S., Smith, Steven R., Sergienko, Eduard, Pinkerton, Anthony B.

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Aberrant Lipid Metabolism in Anaplastic Thyroid Carcinoma Reveals Stearoyl CoA Desaturase 1 as a Novel Therapeutic Target von von Roemeling, Christina A, Marlow, Laura A, Pinkerton, Anthony B, Crist, Angela, Miller, James, Tun, Han W, Smallridge, Robert C, Copland, John A

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Pathophysiological Role of Vascular Smooth Muscle Alkaline Phosphatase in Medial Artery Calcification von Sheen, Campbell R, Kuss, Pia, Narisawa, Sonoko, Yadav, Manisha C, Nigro, Jessica, Wang, Wei, Chhea, T Nicole, Sergienko, Eduard A, Kapoor, Kapil, Jackson, Michael R, Hoylaerts, Marc F, Pinkerton, Anthony B, O'Neill, W Charles, Millán, José Luis

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Characterization of the Zika virus two-component NS2B-NS3 protease and structure-assisted identification of allosteric small-molecule antagonists von Shiryaev, Sergey A., Farhy, Chen, Pinto, Antonella, Huang, Chun-Teng, Simonetti, Nicole, Ngono, Annie Elong, Dewing, Antimone, Shresta, Sujan, Pinkerton, Anthony B., Cieplak, Piotr, Strongin, Alex Y., Terskikh, Alexey V.

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Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11 von Li, Jing, Yakushi, Tanya, Parlati, Francesco, Mackinnon, Andrew L, Perez, Christian, Ma, Yuyong, Carter, Kyle P, Colayco, Sharon, Magnuson, Gavin, Brown, Brock, Nguyen, Kevin, Vasile, Stefan, Suyama, Eigo, Smith, Layton H, Sergienko, Eduard, Pinkerton, Anthony B, Chung, Thomas D Y, Palmer, Amy E, Pass, Ian, Hess, Sonja, Cohen, Seth M, Deshaies, Raymond J

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Discovery of DS68702229 as a Potent, Orally Available NAMPT (Nicotinamide Phosphoribosyltransferase) Activator von Akiu, Mayuko, Tsuji, Takashi, Iida, Kouki, Sogawa, Yoshitaka, Terayama, Koji, Yokoyama, Mika, Tanaka, Jun, Asano, Daigo, Honda, Tomohiro, Sakurai, Ken, Pinkerton, Anthony B., Nakamura, Tsuyoshi

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Overexpression of tissue-nonspecific alkaline phosphatase (TNAP) in endothelial cells accelerates coronary artery disease in a mouse model of familial hypercholesterolemia von Romanelli, Filippo, Corbo, AnthonyMarco, Salehi, Maryam, Yadav, Manisha C, Salman, Soha, Petrosian, David, Rashidbaigi, Omid J, Chait, Jesse, Kuruvilla, Jes, Plummer, Maria, Radichev, Ilian, Margulies, Kenneth B, Gerdes, A Martin, Pinkerton, Anthony B, Millán, José Luis, Savinov, Alexei Y, Savinova, Olga V

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Discovery of 5-((5-chloro-2-methoxyphenyl)sulfonamido)nicotinamide (SBI-425), a potent and orally bioavailable tissue-nonspecific alkaline phosphatase (TNAP) inhibitor von Pinkerton, Anthony B., Sergienko, Eduard, Bravo, Yalda, Dahl, Russell, Ma, Chen-Ting, Sun, Qing, Jackson, Michael R., Cosford, Nicholas D.P., Millán, José Luis

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Optimization of a urea-containing series of nicotinamide phosphoribosyltransferase (NAMPT) activators von Pinkerton, Anthony B., Sessions, E. Hampton, Hershberger, Paul, Maloney, Patrick R., Peddibhotla, Satyamaheshwar, Hopf, Meghan, Sergienko, Eduard, Ma, Chen-Ting, Smith, Layton H., Jackson, Michael R., Tanaka, Jun, Tsuji, Takashi, Akiu, Mayuko, Cohen, Steven E., Nakamura, Tsuyoshi, Gardell, Stephen J.

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Non-Metathesis Ruthenium-Catalyzed C−C Bond Formation von Trost, Barry M, Toste, F. Dean, Pinkerton, Anthony B

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Arylmethylamino steroids as antiparasitic agents von Krieg, Reimar, Jortzik, Esther, Goetz, Alice-Anne, Blandin, Stéphanie, Wittlin, Sergio, Elhabiri, Mourad, Rahbari, Mahsa, Nuryyeva, Selbi, Voigt, Kerstin, Dahse, Hans-Martin, Brakhage, Axel, Beckmann, Svenja, Quack, Thomas, Grevelding, Christoph G., Pinkerton, Anthony B., Schönecker, Bruno, Burrows, Jeremy, Davioud-Charvet, Elisabeth, Rahlfs, Stefan, Becker, Katja

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Repurposing antimalarial aminoquinolines and related compounds for treatment of retinal neovascularization von McAnally, Danielle, Siddiquee, Khandaker, Gomaa, Ahmed, Szabo, Andras, Vasile, Stefan, Maloney, Patrick R, Divlianska, Daniela B, Peddibhotla, Satyamaheshwar, Morfa, Camilo J, Hershberger, Paul, Falter, Rebecca, Williamson, Robert, Terry, David B, Farjo, Rafal, Pinkerton, Anthony B, Qi, Xiaping, Quigley, Judith, Boulton, Michael E, Grant, Maria B, Smith, Layton H

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Glucose 6-phosphate dehydrogenase 6-phosphogluconolactonase: characterization of the Plasmodium vivax enzyme and inhibitor studies von Haeussler, Kristina, Berneburg, Isabell, Jortzik, Esther, Hahn, Julia, Rahbari, Mahsa, Schulz, Norma, Preuss, Janina, Zapol'skii, Viktor A, Bode, Lars, Pinkerton, Anthony B, Kaufmann, Dieter E, Rahlfs, Stefan, Becker, Katja

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Author Correction: Arylmethylamino steroids as antiparasitic agents von Krieg, Reimar, Jortzik, Esther, Goetz, Alice-Anne, Blandin, Stéphanie, Wittlin, Sergio, Elhabiri, Mourad, Rahbari, Mahsa, Nuryyeva, Selbi, Voigt, Kerstin, Dahse, Hans-Martin, Brakhage, Axel, Beckmann, Svenja, Quack, Thomas, Grevelding, Christoph G., Pinkerton, Anthony B., Schönecker, Bruno, Burrows, Jeremy, Davioud-Charvet, Elisabeth, Rahlfs, Stefan, Becker, Katja

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Chronic Kidney Disease-Induced Arterial Media Calcification in Rats Prevented by Tissue Non-Specific Alkaline Phosphatase Substrate Supplementation Rather Than Inhibition of the En... von Opdebeeck, Britt, Neven, Ellen, Millán, José Luis, Pinkerton, Anthony B., D’Haese, Patrick C., Verhulst, Anja

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Inhibition of tissue‐nonspecific alkaline phosphatase protects against medial arterial calcification and improves survival probability in the CKD‐MBD mouse model von Tani, Takashi, Fujiwara, Megumi, Orimo, Hideo, Shimizu, Akira, Narisawa, Sonoko, Pinkerton, Anthony B, Millán, José Luis, Tsuruoka, Shuichi

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Discovery of 4-oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-nitrobenzoate (ML221) as a functional antagonist of the apelin (APJ) receptor von Maloney, Patrick R., Khan, Pasha, Hedrick, Michael, Gosalia, Palak, Milewski, Monika, Li, Linda, Roth, Gregory P., Sergienko, Eduard, Suyama, Eigo, Sugarman, Eliot, Nguyen, Kevin, Mehta, Alka, Vasile, Stefan, Su, Ying, Stonich, Derek, Nguyen, Hung, Zeng, Fu-Yue, Novo, Arianna Mangravita, Vicchiarelli, Michael, Diwan, Jena, Chung, Thomas D.Y., Smith, Layton H., Pinkerton, Anthony B.

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β-Arrestin-Biased Allosteric Modulator of NTSR1 Selectively Attenuates Addictive Behaviors von Slosky, Lauren M., Bai, Yushi, Toth, Krisztian, Ray, Caroline, Rochelle, Lauren K., Badea, Alexandra, Chandrasekhar, Rahul, Pogorelov, Vladimir M., Abraham, Dennis M., Atluri, Namratha, Peddibhotla, Satyamaheshwar, Hedrick, Michael P., Hershberger, Paul, Maloney, Patrick, Yuan, Hong, Li, Zibo, Wetsel, William C., Pinkerton, Anthony B., Barak, Lawrence S., Caron, Marc G.

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Stereocontrolled Total Synthesis of (+)-Streptazolin by a Palladium-Catalyzed Reductive Diyne Cyclization von Trost, Barry M., Chung, Cheol K., Pinkerton, Anthony B.

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Pharmacological TNAP inhibition efficiently inhibits arterial media calcification in a warfarin rat model but deserves careful consideration of potential physiological bone formati... von Opdebeeck, Britt, Neven, Ellen, Millán, José Luis, Pinkerton, Anthony B., D'Haese, Patrick C., Verhulst, Anja

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