Src kinase-induced phosphorylation of annexin A2 mediates glucocorticoid resistance in MLL-rearranged infant acute lymphoblastic leukemia von Spijkers-Hagelstein, J A P, Mimoso Pinhanços, S, Schneider, P, Pieters, R, Stam, R W

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Chemical genomic screening identifies LY294002 as a modulator of glucocorticoid resistance in MLL-rearranged infant ALL von Spijkers-Hagelstein, J A P, Pinhanços, S S, Schneider, P, Pieters, R, Stam, R W

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The HDAC inhibitor panobinostat (LBH589) exerts in vivo anti-leukaemic activity against MLL-rearranged acute lymphoblastic leukaemia and involves the RNF20/RNF40/WAC-H2B ubiquitina... von Garrido Castro, P, van Roon, E H J, Pinhanços, S S, Trentin, L, Schneider, P, Kerstjens, M, te Kronnie, G, Heidenreich, O, Pieters, R, Stam, R W

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Versican expression is an adverse prognostic factor in MLL- rearranged infant acute lymphoblastic leukaemia von Driessen, Emma M.C, Pinhanços, Sandra S. Mimoso, Schneider, Pauline, de Lorenzo, Paola, Valsecchi, Maria G, Pieters, Rob, Stam, Ronald W

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MEK inhibition is a promising therapeutic strategy for MLL-rearranged infant acute lymphoblastic leukemia patients carrying RAS mutations von Kerstjens, Mark, Driessen, Emma M C, Willekes, Merel, Pinhanços, Sandra S, Schneider, Pauline, Pieters, Rob, Stam, Ronald W

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AMP-activated Protein Kinase Activation by 5-Aminoimidazole-4-carbox-amide-1-β-d-ribofuranoside (AICAR) Reduces Lipoteichoic Acid-induced Lung Inflammation von Hoogendijk, Arie J., Pinhanços, Sandra S., van der Poll, Tom, Wieland, Catharina W.

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IDF2022-0557 High-throughput screening identifies microRNAs capable of rescuing beta cells from glucolipotoxicity-induced cell death von Pinhanços, S., Oliveira, J., Santos, J., Gotthard, M., Ferreira, L., Jones, J., Fernandes, H.

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Trametinib inhibits RAS -mutant MLL -rearranged acute lymphoblastic leukemia at specific niche sites and reduces ERK phosphorylation in vivo von Kerstjens, Mark, Pinhancos, Sandra S, Castro, Patricia Garrido, Schneider, Pauline, Wander, Priscilla, Pieters, Rob, Stam, Ronald W

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Irinotecan Induces Disease Remission in Xenograft Mouse Models of Pediatric MLL-Rearranged Acute Lymphoblastic Leukemia von Kerstjens, Mark, Garrido Castro, Patricia, Pinhanços, Sandra S., Schneider, Pauline, Wander, Priscilla, Pieters, Rob, Stam, Ronald W.

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IDF23-0097 Use of extracellular vesicles miRNAs as markers of diabetes reversion in metabolic surgery patients von Oliveira, J., Pinhanços, S., Correia, T., Mesquita, I., Marcos, M., Soares, P., Jones, J., Fernandes, H., Santos, J.

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The HDAC inhibitor panobinostat von Trentin, L, Stam, R W, te Kronnie, G, Garrido Castro, P, Heidenreich, O, Schneider, P, van Roon, E H J, Pinhanços, S S, Kerstjens, M, Pieters, R

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Serum homocysteine: Interplay with other circulating and genetic factors in association to Alzheimer's type dementia von Cascalheira, José F., João, Sara S., Pinhanços, Sandra S., Castro, Rita, Palmeira, Manuela, Almeida, Sofia, Faria, Maria C., Domingues, Fernanda C.

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Irinotecan Induces Complete Remission in MLL -Rearranged Acute Lymphoblastic Leukemia Xenografts von Garrido Castro, Patricia, Kerstjens, Mark, Pinhanços, Sandra S, Schneider, Pauline, Wander, Priscilla, Pieters, Rob, Stam, Ronald

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Abstract 1925: High-throughput drug library screening identifies potent drugs and novel drug targets for high-risk acute leukemia in children von Wander, Priscilla, Pinhanços, Sandra S., Koopmans, Bianca, Dolman, M. Emmy M., Schneider, Pauline, Castro, Patricia Garrido, Jones, Luke, Arentsen-Peters, Susan T.C.J.M., Kerstjens, Mark, Molenaar, Jan, Caron, Huib N., Pieters, Rob, Zwaan, Michel C., Stam, Ronald W.

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Preclinical efficacy of gemcitabine in MLL-rearranged infant acute lymphoblastic leukemia von Wander, Priscilla, Cheung, Laurence C., Pinhanҫos, Sandra S., Jones, Luke, Kerstjens, Mark, Arentsen-Peters, Susan T.C.J.M., Singh, Sajla, Chua, Grace-Alyssa, Castro, Patricia Garrido, Schneider, Pauline, Dolman, M. Emmy M., Koopmans, Bianca, Molenaar, Jan J., Pieters, Rob, Zwaan, C. Michel, Kotecha, Rishi S., Stam, Ronald W.

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MEK Inhibition Is a Promising Therapeutic Strategy for MLL-Rearranged Infant ALL Patients Carrying RAS Mutations von Kerstjens, Mark JB, Driessen, Emma MC, Willekes, Merel, Mimoso Pinhancos, Sandra S, Pieters, Rob, Stam, Ronald

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High-throughput drug screening reveals Pyrvinium pamoate as effective candidate against pediatric MLL-rearranged acute myeloid leukemia von Wander, Priscilla, Arentsen-Peters, Susan T.C.J.M., Pinhanҫos, Sandra S., Koopmans, Bianca, Dolman, M.Emmy M., Ariese, Rijndert, Bos, Frank L., Castro, Patricia Garrido, Jones, Luke, Schneider, Pauline, Navarro, Miriam Guillen, Molenaar, Jan J., Rios, Anne C., Zwaan, C. Michel, Stam, Ronald W.

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Unravelling the Mirnome of MLL-Rearranged Acute Lymphoblastic Leukemia von Garrido Castro, Patricia, Bueno, Clara, van Roon, Eddy HJ, Mimoso Pinhancos, Sandra S, Schneider, Pauline, Willekes, Merel, Menendez, Pablo, Pieters, Rob, Stam, Ronald

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The Histone Deacetylase Inhibitor Panobinostat (LBH-589) Exerts Anti-Leukaemic Activity in a MLL-Rearranged ALL Xenograft Mouse Model von Garrido Castro, Patricia, Van Roon, Eddy HJ, Mimoso Pinhancos, Sandra S, Schneider, Pauline, Kerstjens, Mark JB, Willekes, Merel, Pieters, Rob, Stam, Ronald

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Decitabine mildly attenuates MLL‐rearranged acute lymphoblastic leukemia in vivo, and represents a poor chemo‐sensitizer von Schneider, Pauline, Castro, Patricia Garrido, Pinhanços, Sandra M., Kerstjens, Mark, Roon, Eddy H., Essing, Anke H.W., Dolman, M. Emmy M., Molenaar, Jan J., Pieters, Rob, Stam, Ronald W.

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