PO-15 - Antiangiogenic small molecule ligands of FGF2 derived from the endogenous inhibitor thrombospondin-1 von Pinessi, D, Foglieni, C, Bugatti, A, Moroni, E, Resovi, A, Ribatti, D, Rusnati, M, Giavazzi, R, Colombo, G, Taraboletti, G

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PO-76 The T3R domain of thrombospondin-1 delays tumor growth and improves tumor response to chemotherapy by remodeling the tumor vasculature von Pinessi, D., Resovi, A., Morosi, L., Borsotti, P., Berndt, A., Giavazzi, R., Zucchetti, M., Taraboletti, G.

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SQSTM1 mutations in frontotemporal lobar degeneration and amyotrophic lateral sclerosis von RUBINO, Elisa, RAINERO, Innocenzo, CECILIA BRUNI, Amalia, GEORGE-HYSLOP, Peter Henry St, SCARPINI, Elio, GALLONE, Salvatore, PINESSI, Lorenzo, CHIO, Adriano, ROGAEVA, Ekaterina, GALIMBERTI, Daniela, FENOGLIO, Pierpaola, GRINBERG, Yakov, ISAIA, Giancarlo, CALVO, Andrea, GENTILE, Salvatore

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Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia von Swarup, Vivek, Hinz, Flora I., Rexach, Jessica E., Noguchi, Ken-ichi, Toyoshiba, Hiroyoshi, Oda, Akira, Hirai, Keisuke, Sarkar, Arjun, Seyfried, Nicholas T., Cheng, Chialin, Haggarty, Stephen J., Grossman, Murray, Van Deerlin, Vivianna M., Trojanowski, John Q., Lah, James J., Levey, Allan I., Kondou, Shinichi, Geschwind, Daniel H.

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Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies von Broce, Iris, Karch, Celeste M, Wen, Natalie, Fan, Chun C, Wang, Yunpeng, Tan, Chin Hong, Kouri, Naomi, Ross, Owen A, Höglinger, Günter U, Muller, Ulrich, Hardy, John, Momeni, Parastoo, Hess, Christopher P, Dillon, William P, Miller, Zachary A, Bonham, Luke W, Rabinovici, Gil D, Rosen, Howard J, Schellenberg, Gerard D, Franke, Andre, Karlsen, Tom H, Veldink, Jan H, Ferrari, Raffaele, Yokoyama, Jennifer S, Miller, Bruce L, Andreassen, Ole A, Dale, Anders M, Desikan, Rahul S, Sugrue, Leo P

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The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease von Inzelberg, Rivka, Meng, Yan, Petersen, Ronald C, Sorbi, Sandro, Baldwin, Clinton T, Lee, Joseph H, Mayeux, Richard, Cupples, L Adrienne, Cuenco, Karen T, Katayama, Taiichi, Wakutani, Yosuke, Der, Sandy D, Pinessi, Lorenzo, Cheng, Rong, Willnow, Thomas E, Kawarai, Toshitaka, Hasegawa, Hiroshi, Gu, Yongjun, Chen, Fusheng, Friedland, Robert P, Rainero, Innocenzo, Fraser, Paul E, Zou, Fanggeng, Bujo, Hideaki, Lunetta, Kathryn L, Andersen, Olav M, Green, Robert C, Pardossi-Piquard, Raphaelle, Shibata, Nobuto, Bruni, Amalia, Graff-Radford, Neill, Rogaeva, Ekaterina, St George-Hyslop, Peter, Bohm, Christopher, Schmitt-Ulms, Gerold, Dickson, Dennis, Farrer, Lindsay A, Hampe, Wolfgang, Song, You-Qiang, Younkin, Steven, Duara, Ranjan

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A C6orf10/LOC101929163 locus is associated with age of onset in C9orf72 carriers von Zhang, Ming, Ferrari, Raffaele, Tartaglia, Maria Carmela, Keith, Julia, Surace, Ezequiel I, Wolf, Uri, Sato, Christine, Grinberg, Mark, Liang, Yan, Xi, Zhengrui, Dupont, Kyle, McGoldrick, Philip, Weichert, Anna, McKeever, Paul M, Schneider, Raphael, McCorkindale, Michael D, Manzoni, Claudia, Rademakers, Rosa, Graff-Radford, Neill R, Dickson, Dennis W, Parisi, Joseph E, Boeve, Bradley F, Petersen, Ronald C, Miller, Bruce L, Seeley, William W, van Swieten, John C, van Rooij, Jeroen, Pijnenburg, Yolande, van der Zee, Julie, Van Broeckhoven, Christine, Le Ber, Isabelle, Van Deerlin, Vivianna, Suh, EunRan, Rohrer, Jonathan D, Mead, Simon, Graff, Caroline, Öijerstedt, Linn, Pickering-Brown, Stuart, Rollinson, Sara, Rossi, Giacomina, Tagliavini, Fabrizio, Brooks, William S, Dobson-Stone, Carol, Halliday, Glenda M, Hodges, John R, Piguet, Olivier, Binetti, Giuliano, Benussi, Luisa, Ghidoni, Roberta, Nacmias, Benedetta, Sorbi, Sandro, Bruni, Amalia C, Galimberti, Daniela, Scarpini, Elio, Rainero, Innocenzo, Rubino, Elisa, Clarimon, Jordi, Lleó, Alberto, Ruiz, Agustin, Hernández, Isabel, Pastor, Pau, Diez-Fairen, Monica, Borroni, Barbara, Pasquier, Florence, Deramecourt, Vincent, Lebouvier, Thibaud, Perneczky, Robert, Diehl-Schmid, Janine, Grafman, Jordan, Huey, Edward D, Mayeux, Richard, Nalls, Michael A, Hernandez, Dena, Singleton, Andrew, Momeni, Parastoo, Zeng, Zhen, Hardy, John, Robertson, Janice, Zinman, Lorne, Rogaeva, Ekaterina

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Prioritization of Drug Targets for Neurodegenerative Diseases by Integrating Genetic and Proteomic Data From Brain and Blood von Ge, Yi-Jun, Zhang, Ya-Ru, Huang, Yu-Yuan, Dong, Qiang, Tan, Lan, Ferrari, Raffaele, Ramasamy, Adaikalavan, Kwok, John B.J., Dobson-Stone, Carol, Schofield, Peter R., Halliday, Glenda M., Piguet, Olivier, Bartley, Lauren, Thompson, Elizabeth, Haan, Eric, Hernández, Isabel, Ruiz, Agustín, Boada, Mercè, Cruchaga, Carlos, Benussi, Luisa, Galimberti, Daniela, Fenoglio, Chiara, Scarpini, Elio, Lleó, Alberto, Nilsson, Karin, Mackenzie, Ian R.A., Hsiung, Ging-Yuek R., Mann, David M.A., Morris, Christopher M., Attems, Johannes, Thomas, Alan J., Pietrini, P., Huey, Edward D., Tierney, Michael C., Pastor, Pau, Razquin, Cristina, Ortega-Cubero, Sara, Perneczky, Robert, Diehl-Schmid, Janine, Alexopoulos, Panagiotis, Kurz, Alexander, Rainero, Innocenzo, Rogaeva, Ekaterina, Rossi, Giacomina, Rowe, James B., Schlachetzki, Johannes C.M., Uphill, James, Collinge, John, Mead, Simon, Danek, Adrian, Van Langenhove, Tim, Cappa, Stefano F., Hannequin, Didier, Vercelletto, Martine, Brice, Alexis, Nacmias, Benedetta, Bagnoli, Silvia, Nielsen, Jørgen E., Ibach, Bernd, Gasparoni, Gilles, Gu, Wei, Warren, Jason D., Spillantini, Maria Grazia, Morris, Huw R., Snowden, Julie S., Rollinson, Sara, Richardson, Anna, Gerhard, Alexander, Bruni, Amalia C., Maletta, Raffaele, Cupidi, Chiara, Gallo, Maura, Smirne, Nicoletta, Rademakers, Rosa, Baker, Matt, Dickson, Dennis W., Petersen, Ronald C., Knopman, David, Boeve, Bradley F., Parisi, Joseph E., Seeley, William W., Miller, Bruce L., Karydas, Anna M., van Swieten, John C., Seelaar, Harro, Pijnenburg, Yolande A.L., Logroscino, Giancarlo, Capozzo, Rosa, Puca, Annibale A., Franceschi, Massimo, Postiglione, Alfredo, Sorrentino, Paolo, Kristiansen, Mark, Chiang, Huei-Hsin, Graff, Caroline, Rollin, Adeline, Lebert, Florence, Kapogiannis, Dimitrios, Ferrucci, Luigi, Hardy, John

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Gene-based association studies report genetic links for clinical subtypes of frontotemporal dementia von Mishra, Aniket, Ferrari, Raffaele, Heutink, Peter, Hardy, John, Pijnenburg, Yolande, Posthuma, Danielle

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Gene Expression Imputation Across Multiple Tissue Types Provides Insight Into the Genetic Architecture of Frontotemporal Dementia and Its Clinical Subtypes von Reus, Lianne M., Pasaniuc, Bogdan, Posthuma, Danielle, Boltz, Toni, Ferrari, Raffaele, Hernandez, Dena G., Nalls, Michael A., Rohrer, Jonathan D., Ramasamy, Adaikalavan, Brooks, William S., Halliday, Glenda M., Piguet, Olivier, Bartley, Lauren, Hernández, Isabel, Ruiz, Agustín, Boada, Mercè, Borroni, Barbara, Padovani, Alessandro, Cruchaga, Carlos, Cairns, Nigel J., Benussi, Luisa, Ghidoni, Roberta, Forloni, Gianluigi, Galimberti, Daniela, Fenoglio, Chiara, Scarpini, Elio, Blesa, Rafael, Mackenzie, Ian R.A., Hsiung, Ging-Yuek R., Mann, David M.A., Attems, Johannes, Thomas, Alan J., Huey, Edward D., Tierney, Michael C., Razquin, Cristina, Ortega-Cubero, Sara, Alonso, Elena, Perneczky, Robert, Diehl-Schmid, Janine, Alexopoulos, Panagiotis, Rubino, Elisa, Rogaeva, Ekaterina, St. George-Hyslop, Peter, Rossi, Giacomina, Rowe, James B., Schlachetzki, Johannes C.M., Uphill, James, Collinge, John, Danek, Adrian, Van Deerlin, Vivianna M., Trojanowski, John Q., van der Zee, Julie, Cappa, Stefano F., Hannequin, Didier, Brice, Alexis, Nacmias, Benedetta, Sorbi, Sandro, Bagnoli, Silvia, Piaceri, Irene, Nielsen, Jørgen E., Hjermind, Lena E., Riemenschneider, Matthias, Ibach, Bernd, Gasparoni, Gilles, Pichler, Sabrina, Warren, Jason D., Morris, Huw R., Heutink, Peter, Snowden, Julie S., Rollinson, Sara, Gerhard, Alexander, Bruni, Amalia C., Frangipane, Francesca, Cupidi, Chiara, Anfossi, Maria, Gallo, Maura, Smirne, Nicoletta, Rademakers, Rosa, Dickson, Dennis W., Graff-Radford, Neill R., Petersen, Ronald C., Josephs, Keith A., Boeve, Bradley F., Parisi, Joseph E., Seeley, William W., Pijnenburg, Yolande A.L., Scheltens, Philip, Puca, Annibale A., Postiglione, Alfredo, Milan, Graziella, Sorrentino, Paolo, Kristiansen, Mark, Chiang, Huei-Hsin, Graff, Caroline, Kapogiannis, Dimitrios, Ferrucci, Luigi, Pickering-Brown, Stuart, Singleton, Andrew B., Pijnenburg, Yolande A.L., Ophoff, Roel A.

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CXCR4 involvement in neurodegenerative diseases von Bonham, Luke W., Karch, Celeste M., Fan, Chun C., Tan, Chin, Geier, Ethan G., Wang, Yunpeng, Wen, Natalie, Broce, Iris J., Li, Yi, Barkovich, Matthew J., Ferrari, Raffaele, Hardy, John, Momeni, Parastoo, Höglinger, Günter, Müller, Ulrich, Hess, Christopher P., Sugrue, Leo P., Dillon, William P., Schellenberg, Gerard D., Miller, Bruce L., Andreassen, Ole A., Dale, Anders M., Barkovich, A. James, Yokoyama, Jennifer S., Desikan, Rahul S.

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Placebo-Controlled Comparison of Effervescent Acetylsalicylic Acid, Sumatriptan and Ibuprofen in the Treatment of Migraine Attacks von EMSASI, The, Diener, HC, Bussone, G, de Liano, H, Eikermann, A, Englert, R, Floeter, T, Gallai, V, Göbel, H, Hartung, E, Jimenez, MD, Lange, R, Manzoni, GC, Mueller-Schwefe, G, Nappi, G, Pinessi, L, Prat, J, Puca, FM, Titus, F, Voelker, M

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Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS von Taskesen, E., Mishra, A., van der Sluis, S., Ferrari, R., Veldink, J. H., van Es, M. A., Smit, A. B., Posthuma, D., Pijnenburg, Y.

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Mendelian randomization implies no direct causal association between leukocyte telomere length and amyotrophic lateral sclerosis von Gao, Yixin, Wang, Ting, Yu, Xinghao, Zhao, Huashuo, Zeng, Ping

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A family with autosomal dominant leukodystrophy linked to 5q23.2-q23.3 without lamin B1 mutations von Brussino, A., Vaula, G., Cagnoli, C., Panza, E., Seri, M., Di Gregorio, E., Scappaticci, S., Camanini, S., Daniele, D., Bradac, G. B., Pinessi, L., Cavalieri, S., Grosso, E., Migone, N., Brusco, A.

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Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia von Bonham, Luke W., Steele, Natasha Z. R., Karch, Celeste M., Broce, Iris, Geier, Ethan G., Wen, Natalie L., Momeni, Parastoo, Hardy, John, Miller, Zachary A., Gorno-Tempini, Maria Luisa, Hess, Christopher P., Lewis, Patrick, Miller, Bruce L., Seeley, William W., Manzoni, Claudia, Desikan, Rahul S., Baranzini, Sergio E., Ferrari, Raffaele, Yokoyama, Jennifer S.

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Reversible MRI Abnormalities in a Patient with Recurrent Status Migrainosus von Gentile, S, Rainero, I, Daniele, D, Binello, E, Valfrè, W, Pinessi, L

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Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of lon... von van der Lee, Sven J., Conway, Olivia J., Jansen, Iris, Carrasquillo, Minerva M., Kleineidam, Luca, van den Akker, Erik, Hernández, Isabel, van Eijk, Kristel R., Stringa, Najada, Chen, Jason A., Zettergren, Anna, Andlauer, Till F. M., Diez-Fairen, Monica, Simon-Sanchez, Javier, Lleó, Alberto, Zetterberg, Henrik, Nygaard, Marianne, Blauwendraat, Cornelis, Savage, Jeanne E., Mengel-From, Jonas, Moreno-Grau, Sonia, Wagner, Michael, Fortea, Juan, Keogh, Michael J., Blennow, Kaj, Skoog, Ingmar, Friese, Manuel A., Pletnikova, Olga, Zulaica, Miren, Lage, Carmen, de Rojas, Itziar, Riedel-Heller, Steffi, Illán-Gala, Ignacio, Wei, Wei, Jeune, Bernard, Orellana, Adelina, Then Bergh, Florian, Wang, Xue, Hulsman, Marc, Beker, Nina, Tesi, Niccolo, Morris, Christopher M., Indakoetxea, Begoña, Collij, Lyduine E., Scherer, Martin, Morenas-Rodríguez, Estrella, Ironside, James W., van Berckel, Bart N. M., Wiendl, Heinz, Strickland, Samantha L., Pastor, Pau, Rodríguez Rodríguez, Eloy, Boeve, Bradley F., Petersen, Ronald C., Ferman, Tanis J., van Gerpen, Jay A., Reinders, Marcel J. T., Uitti, Ryan J., Tárraga, Lluís, Maier, Wolfgang, Dols-Icardo, Oriol, Kawalia, Amit, Dalmasso, Maria Carolina, Boada, Mercè, Zettl, Uwe K., van Schoor, Natasja M., Beekman, Marian, Allen, Mariet, Masliah, Eliezer, de Munain, Adolfo López, Pantelyat, Alexander, Wszolek, Zbigniew K., Ross, Owen A., Dickson, Dennis W., Graff-Radford, Neill R., Knopman, David, Rademakers, Rosa, Lemstra, Afina W., Pijnenburg, Yolande A. L., Scheltens, Philip, Gasser, Thomas, Chinnery, Patrick F, Hemmer, Bernhard, Huisman, Martijn A., Troncoso, Juan, Moreno, Fermin, Nohr, Ellen A., Sørensen, Thorkild I. A., Heutink, Peter, Sánchez-Juan, Pascual, Posthuma, Danielle, Clarimón, Jordi, Christensen, Kaare, Ertekin-Taner, Nilüfer, Scholz, Sonja W., Ramirez, Alfredo, Ruiz, Agustín, Slagboom, Eline, van der Flier, Wiesje M., Holstege, Henne

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Frovatriptan versus other triptans in the acute treatment of migraine with aura attacks: Pooled analysis of double-blind, randomized, cross-over, multicenter, studies von Evers, S, Summ, O, Ferrari, M, Savi, L, Pinessi, L, Omboni, S, Lisotto, C, Zanchin, G, Zava, D

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Relapse in acute migraine treatment: Comparison of frovatriptan with other triptans von Evers, S, Summ, O, Ferrari, M, Savi, L, Omboni, S, Lisotto, C, Zanchin, G, Zava, D, Pinessi, L

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