PIWI pathway: bridging acute myeloid leukemia stemness and cellular differentiation von Garcia-Silva, M R, Márquez, M E, Pinello, N

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Intron retention is regulated by altered MeCP2-mediated splicing factor recruitment von Wong, Justin J. -L., Gao, Dadi, Nguyen, Trung V., Kwok, Chau-To, van Geldermalsen, Michelle, Middleton, Rob, Pinello, Natalia, Thoeng, Annora, Nagarajah, Rajini, Holst, Jeff, Ritchie, William, Rasko, John E. J.

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RBM3 regulates temperature sensitive miR-142-5p and miR-143 (thermomiRs), which target immune genes and control fever von Wong, Justin J-L, Au, Amy Y M, Gao, Dadi, Pinello, Natalia, Kwok, Chau-To, Thoeng, Annora, Lau, Katherine A, Gordon, Jane E A, Schmitz, Ulf, Feng, Yue, Nguyen, Trung V, Middleton, Robert, Bailey, Charles G, Holst, Jeff, Rasko, John E J, Ritchie, William

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Murine and related chapparvoviruses are nephro-tropic and produce novel accessory proteins in infected kidneys von Lee, Q, Lee, Q, Padula, MP, Padula, MP, Pinello, N, Pinello, N, Williams, SH, Williams, SH, O’Rourke, MB, Fumagalli, MJ, Fumagalli, MJ, Orkin, JD, Orkin, JD, Song, R, Song, R, Shaban, B, Shaban, B, Brenner, O, Brenner, O, Pimanda, JE, https://orcid.org/0000-0002-0509-8962, Pimanda, JE, Weninger, W, Weninger, W, de Souza, WM, de Souza, WM, Melin, AD, Melin, AD, Wong, JJL, Wong, JJL, Crim, MJ, Crim, MJ, Monette, S, Monette, S, Roediger, B, Roediger, B, Jolly, CJ, Jolly, CJ, https://orcid.org/0000-0002-9307-1056

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Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM von Chen, Huidong, Albergante, Luca, Hsu, Jonathan Y., Lareau, Caleb A., Lo Bosco, Giosuè, Guan, Jihong, Zhou, Shuigeng, Gorban, Alexander N., Bauer, Daniel E., Aryee, Martin J., Langenau, David M., Zinovyev, Andrei, Buenrostro, Jason D., Yuan, Guo-Cheng, Pinello, Luca

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Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigms von Hu, Haichuan, Piotrowska, Zofia, Hare, Patricia J., Chen, Huidong, Mulvey, Hillary E., Mayfield, Aislinn, Noeen, Sundus, Kattermann, Krystina, Greenberg, Max, Williams, August, Riley, Amanda K., Wilson, Jarad J., Mao, Ying-Qing, Huang, Ruo-Pan, Banwait, Mandeep K., Ho, Jeffrey, Crowther, Giovanna S., Hariri, Lida P., Heist, Rebecca S., Kodack, David P., Pinello, Luca, Shaw, Alice T., Mino-Kenudson, Mari, Hata, Aaron N., Sequist, Lecia V., Benes, Cyril H., Niederst, Matthew J., Engelman, Jeffrey A.

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Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci von Canver, Matthew C, Lessard, Samuel, Pinello, Luca, Wu, Yuxuan, Ilboudo, Yann, Stern, Emily N, Needleman, Austen J, Galactéros, Frédéric, Brugnara, Carlo, Kutlar, Abdullah, McKenzie, Colin, Reid, Marvin, Chen, Diane D, Das, Partha Pratim, A Cole, Mitchel, Zeng, Jing, Kurita, Ryo, Nakamura, Yukio, Yuan, Guo-Cheng, Lettre, Guillaume, Bauer, Daniel E, Orkin, Stuart H

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A European randomised controlled trial of the addition of etoposide to standard vincristine and carboplatin induction as part of an 18-month treatment programme for childhood (≤16 ... von Gnekow, Astrid K., Walker, David A., Kandels, Daniela, Picton, Susan, Giorgio Perilongo, Grill, Jacques, Stokland, Tore, Sandstrom, Per Eric, Warmuth-Metz, Monika, Pietsch, Torsten, Giangaspero, Felice, Schmidt, René, Faldum, Andreas, Kilmartin, Denise, De Paoli, Angela, De Salvo, Gian Luca, Gnekow, Astrid K., Slavc, Irene, Perilongo, Giorgio, Picton, Sue, Walker, David, Stokland, Tore, Sandstrom, Per Erik, Clausen, Niels, Arola, Mikko, Jonsson, Olafur Gisli, Cruz, Ofelia, Navajas, Aurora, Teijeiro, Anna, Grill, Jacques, Kalifa, Chantal, Raquin, Marie-Anne, Verlooy, Joris, Hans, Volkmar, Pietsch, Torsten, Scheurlen, Wolfram, Hainfellner, Johannes, Giangaspero, Felice, Ironside, James, Robson, Keith, Skullerud, Kari, Scheie, David, NN, Ruchoux, Marie-Madeleine, Jouvet, Anne, Figarella-Branger, Dominique, Lellouch-Toubiana, Arielle, Warmuth-Metz, Monika, Prayer, Daniela, Calderone, Milena, Jaspan, Tim, Bakke, Soren Jacob, Vazquez, Eli, Couanet, Dominique, Kortmann, Rolf D., Diekmann, Karin, Scarzello, Giovanni, Taylor, Roger, Lote, Knut, Giralt, Jordi, Carrie, Christian, Habrand, Jean Louis, Soerensen, Niels, Czech, Thomas, Chumas, Paul, Gustavson, Bengt, Zerah, Michel, Wabbels, Bettina, Pinello, Maria Luisa, Fielder, Alistair, Simmons, Ian, Christoffersen, Terje, Calaminus, Gabriele, Brockmann, Knut, Straeter, Ronald, Ebinger, Friedrich, Hernaiz-Driever, Pablo, Lackner, Herwig, Kennedy, Colin, Glaser, Adam, Stromberg, Bo, Indiano, Jose Ma, Rodary, Chantal, Bouffet, Eric, Frappaz, Didier, Faldum, Andreas, Emser, Angela, De Salvo, Gian Luca, Stephens, Suzanne, Machin, David, Le Deley, Marie-Cécile, Egeland, Thore, Freemann, Carolyn, Schrappe, Martin, Sposto, Richard

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Combined +58 and +55 BCL11A enhancer Editing Yields Exceptional Efficiency, Specificity and HbF Induction in Human and NHP Preclinical Models von Zeng, Jing, Demirci, Selami, Nguyen, My Anh, Lin, Linda Yingqi, Maitland, Stacy A., Mintzer, Esther, Wu, Yuxuan, Pellin, Danilo, Tangprasittipap, Amornrat, Vong, Chokdee, Porter, Shaina N., Luk, Kevin, Liu, Pengpeng, Katta, Varun, Ciuculescu, Marioara-Felicia, Abriss, Daniela, Hsu, Jonathan, Uchida, Naoya, Essawi, Khaled, Donahue, Robert, Petri, Karl, Pattanayak, Vikram, Pinello, Luca, Brendel, Christian, Williams, David A, Manis, John P, Tsai, Shengdar Q., Pruett-Miller, Shondra M., Joung, J. Keith, Songdej, Duantida, Hongeng, Suradej, Armant, Myriam, Wolfe, Scot A., Tisdale, John F., Bauer, Daniel E.

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Abstract 3867: Chromatin modification driving sub-clonal resistance to KRAS G12C combination therapies in KRAS mutant non-small cell lung cancer von Li, Chendi, Qin, Qian, Syed, Mohammed Usman, Nimbalkar, Anahita, Karakyriakou, Barbara, Clark, Sarah E., Saiki, Anne Y., Hughes, Paul E., Ott, Chris, Pinello, Luca, Hata, Aaron N.

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Functionally distinct patterns of nucleosome remodeling at enhancers in glucocorticoid-treated acute lymphoblastic leukemia von Wu, Jennifer N, Pinello, Luca, Yissachar, Elinor, Wischhusen, Jonathan W, Yuan, Guo-Cheng, Roberts, Charles W M

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Single-cell analysis and functional characterization uncover the stem cell hierarchies and developmental origins of rhabdomyosarcoma von Wei, Yun, Qin, Qian, Yan, Chuan, Hayes, Madeline N, Garcia, Sara P, Xi, Haibin, Do, Daniel, Jin, Alexander H, Eng, Tiffany C, McCarthy, Karin M, Adhikari, Abhinav, Onozato, Maristela L, Spentzos, Dimitrios, Neilsen, Gunnlaugur P, Iafrate, A John, Wexler, Leonard H, Pyle, April D, Suvà, Mario L, Dela Cruz, Filemon, Pinello, Luca, Langenau, David M

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Abstract B080: Non-genetic determinants driving sub-clonal resistance to KRAS G12C combination therapies in KRAS mutant non-small cell lung cancer von Li, Chendi, Graser, Christopher J, Qin, Qian, Syed, Usman M, Karakyriakou, Barbara, Clark, Sarah E, Saiki, Anne Y, Hughes, Paul E, Ott, Christopher, Pinello, Luca, Michor, Franziska, Hata, Aaron N

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Corrigendum to “A European randomised controlled trial of the addition of etoposide to standard vincristine and carboplatin induction as part of an 18-month treatment programme for... von Gnekow, Astrid K., Walker, David A., Kandels, Daniela, Picton, Susan, Giorgio Perilongo, Grill, Jacques, Stokland, Tore, Sandstrom, Per Eric, Warmuth-Metz, Monika, Pietsch, Torsten, Giangaspero, Felice, Schmidt, René, Faldum, Andreas, Kilmartin, Denise, De Paoli, Angela, De Salvo, Gian Luca, Gnekow, Astrid K., Slavc, Irene, Perilongo, Giorgio, Picton, Sue, Walker, David, Stokland, Tore, Sandstrom, Per Erik, Clausen, Niels, Arola, Mikko, Jonsson, Olafur Gisli, Cruz, Ofelia, Navajas, Aurora, Teijeiro, Anna, Grill, Jacques, Kalifa, Chantal, Raquin, Marie-Anne, Verlooy, Joris, Hans, Volkmar, Pietsch, Torsten, Scheurlen, Wolfram, Hainfellner, Johannes, Giangaspero, Felice, Ironside, James, Robson, Keith, Skullerud, Kari, Scheie, David, NN, Ruchoux, Marie-Madeleine, Jouvet, Anne, Figarella-Branger, Dominique, Lellouch-Toubiana, Arielle, Warmuth-Metz, Monika, Prayer, Daniela, Calderone, Milena, Jaspan, Tim, Bakke, Soren Jacob, Vazquez, Eli, Couanet, Dominique, Kortmann, Rolf D., Diekmann, Karin, Scarzello, Giovanni, Taylor, Roger, Lote, Knut, Giralt, Jordi, Carrie, Christian, Habrand, Jean Louis, Soerensen, Niels, Czech, Thomas, Chumas, Paul, Gustavson, Bengt, Zerah, Michel, Wabbels, Bettina, Pinello, Maria Luisa, Fielder, Alistair, Simmons, Ian, Christoffersen, Terje, Calaminus, Gabriele, Brockmann, Knut, Straeter, Ronald, Ebinger, Friedrich, Hernaiz-Driever, Pablo, Lackner, Herwig, Kennedy, Colin, Glaser, Adam, Stromberg, Bo, Indiano, Jose Ma, Rodary, Chantal, Bouffet, Eric, Frappaz, Didier, Faldum, Andreas, Emser, Angela, De Salvo, Gian Luca, Stephens, Suzanne, Machin, David, Le Deley, Marie-Cécile, Egeland, Thore, Freemann, Carolyn, Schrappe, Martin, Sposto, Richard

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Rappresentare le spazialità complesse. L’esperienza dell’ALS (Atlante linguistico della Sicilia) von Pinello, Vincenzo

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Functionally distinct patterns of nucleosome remodeling at enhancers in glucocorticoid-treated acute lymphoblastic leukemia von Wu, Jennifer N, Pinello, Luca, Yissachar, Elinor, Wischhusen, Jonathan W, Yuan, Guo-Cheng, Roberts, Charles W. M

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In vitro chemosensitivity of canine mast cell tumors grades II and III to all-trans-retinoic acid (ATRA) von Pinello, K. C, Nagamine, M, Silva, T. C, Matsuzaki, P, Caetano, H. V, Torres, L. N, Fukumasu, H, Avanzo, J. L, Matera, J. M, Dagli, M. L. Z

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Robust And Scalable Learning Of Complex Dataset Topologies Via Elpigraph von Albergante, Luca, Mirkes, Evgeny M, Chen, Huidong, Martin, Alexis, Faure, Louis, Barillot, Emmanuel, Pinello, Luca, Gorban, Alexander N, Zinovyev, Andrei

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Eleven grand challenges in single-cell data science von Lahnemann, D., Koster, J., Szczurek, E., McCarthy, D.J., Hicks, S.C., Robinson, M.D., Vallejos, C.A., Campbell, K.R., Beerenwinkel, N., Mahfouz, A., Pinello, L., Skums, P., Stamatakis, A., Attolini, C.S.O., Aparicio, S., Baaijens, J., Balvert, M., De Barbanson, B., Cappuccio, A., Corleone, G., Dutilh, B.E., Florescu, M., Guryev, V., Holmer, R., Jahn, K., Lobo, T.J., Keizer, E.M., Khatri, I., Kielbasa, S.M., Korbel, J.O., Kozlov, A.M., Kuo, T.H., Lelieveldt, B.P.F., Mandoiu, I.I., Marioni, J.C., Marschall, T., Molder, F., Niknejad, A., Raczkowski, L., Reinders, M., De Ridder, J., Saliba, A.E., Somarakis, A., Stegle, O., Theis, F.J., Yang, H., Zelikovsky, A., McHardy, A.C., Raphael, B.J., Shah, S.R.P., Schonhuth, A.

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Eleven grand challenges in single-cell data science von Lahnemann, D., Koster, J., Szczurek, E., McCarthy, D.J., Hicks, S.C., Robinson, M.D., Vallejos, C.A., Campbell, K.R., Beerenwinkel, N., Mahfouz, A., Pinello, L., Skums, P., Stamatakis, A., Attolini, C.S.O., Aparicio, S., Baaijens, J., Balvert, M., Barbanson, B. de, Cappuccio, A., Corleone, G., Dutilh, B.E., Florescu, M., Guryev, V., Holmer, R., Jahn, K., Lobo, T.J., Keizer, E.M., Khatri, I., Kielbasa, S.M., Korbel, J.O., Kozlov, A.M., Kuo, T.H., Lelieveldt, B.P.F., Mandoiu, I.I., Marioni, J.C., Marschall, T., Molder, F., Niknejad, A., Raczkowski, L., Reinders, M., Ridder, J. de, Saliba, A.E., Somarakis, A., Stegle, O., Theis, F.J., Yang, H., Zelikovsky, A., McHardy, A.C., Raphael, B.J., Shah, S.R.P., Schonhuth, A.

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