PanDrugs2: prioritizing cancer therapies using integrated individual multi-omics data von Jiménez-Santos, María José, Nogueira-Rodríguez, Alba, Piñeiro-Yáñez, Elena, López-Fernández, Hugo, García-Martín, Santiago, Gómez-Plana, Paula, Reboiro-Jato, Miguel, Gómez-López, Gonzalo, Glez-Peña, Daniel, Al-Shahrour, Fátima

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In vivo phosphoproteomics reveals kinase activity profiles that predict treatment outcome in triple-negative breast cancer von Zagorac, Ivana, Fernandez-Gaitero, Sara, Penning, Renske, Post, Harm, Bueno, Maria J., Mouron, Silvana, Manso, Luis, Morente, Manuel M., Alonso, Soledad, Serra, Violeta, Muñoz, Javier, Gómez-López, Gonzalo, Lopez-Acosta, Jose Francisco, Jimenez-Renard, Veronica, Gris-Oliver, Albert, Al-Shahrour, Fatima, Piñeiro-Yañez, Elena, Montoya-Suarez, Jose Luis, Apala, Juan V., Moreno-Torres, Amalia, Colomer, Ramon, Dopazo, Ana, Heck, Albert J. R., Altelaar, Maarten, Quintela-Fandino, Miguel

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STAT3 labels a subpopulation of reactive astrocytes required for brain metastasis von Priego, Neibla, Zhu, Lucía, Monteiro, Cátia, Mulders, Manon, Wasilewski, David, Bindeman, Wendy, Doglio, Laura, Martínez, Liliana, Martínez-Saez, Elena, Ramón y Cajal, Santiago, Megías, Diego, Hernández-Encinas, Elena, Blanco-Aparicio, Carmen, Martínez, Lola, Zarzuela, Eduardo, Muñoz, Javier, Fustero-Torre, Coral, Piñeiro-Yáñez, Elena, Hernández-Laín, Aurelio, Bertero, Luca, Poli, Valeria, Sanchez-Martinez, Melchor, Menendez, Javier A., Soffietti, Riccardo, Bosch-Barrera, Joaquim, Valiente, Manuel

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The use of PanDrugs to prioritize anticancer drug treatments in a case of T-ALL based on individual genomic data von Fernández-Navarro, Pablo, López-Nieva, Pilar, Piñeiro-Yañez, Elena, Carreño-Tarragona, Gonzalo, Martinez-López, Joaquín, Sánchez Pérez, Raúl, Aroca, Ángel, Al-Shahrour, Fátima, Cobos-Fernández, María Ángeles, Fernández-Piqueras, José

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Genomic and immune landscape Of metastatic pheochromocytoma and paraganglioma von Calsina, Bruna, Piñeiro-Yáñez, Elena, Martínez-Montes, Ángel M., Caleiras, Eduardo, Fernández-Sanromán, Ángel, Monteagudo, María, Torres-Pérez, Rafael, Fustero-Torre, Coral, Pulgarín-Alfaro, Marta, Gil, Eduardo, Letón, Rocío, Jiménez, Scherezade, García-Martín, Santiago, Martin, Maria Carmen, Roldán-Romero, Juan María, Lanillos, Javier, Mellid, Sara, Santos, María, Díaz-Talavera, Alberto, Rubio, Ángeles, González, Patricia, Hernando, Barbara, Bechmann, Nicole, Dona, Margo, Calatayud, María, Guadalix, Sonsoles, Álvarez-Escolá, Cristina, Regojo, Rita M., Aller, Javier, Del Olmo-Garcia, Maria Isabel, López-Fernández, Adrià, Fliedner, Stephanie M. J., Rapizzi, Elena, Fassnacht, Martin, Beuschlein, Felix, Quinkler, Marcus, Toledo, Rodrigo A., Mannelli, Massimo, Timmers, Henri J., Eisenhofer, Graeme, Rodríguez-Perales, Sandra, Domínguez, Orlando, Macintyre, Geoffrey, Currás-Freixes, Maria, Rodríguez-Antona, Cristina, Cascón, Alberto, Leandro-García, Luis J., Montero-Conde, Cristina, Roncador, Giovanna, García-García, Juan Fernando, Pacak, Karel, Al-Shahrour, Fátima, Robledo, Mercedes

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Hepatic nutrient and hormone signaling to mTORC1 instructs the postnatal metabolic zonation of the liver von Plata-Gómez, Ana Belén, de Prado-Rivas, Lucía, Sanz, Alba, Deleyto-Seldas, Nerea, García, Fernando, de la Calle Arregui, Celia, Silva, Camila, Caleiras, Eduardo, Graña-Castro, Osvaldo, Piñeiro-Yáñez, Elena, Krebs, Joseph, Leiva-Vega, Luis, Muñoz, Javier, Jain, Ajay, Sabio, Guadalupe, Efeyan, Alejo

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PanDrugs: a novel method to prioritize anticancer drug treatments according to individual genomic data von Piñeiro-Yáñez, Elena, Reboiro-Jato, Miguel, Gómez-López, Gonzalo, Perales-Patón, Javier, Troulé, Kevin, Rodríguez, José Manuel, Tejero, Héctor, Shimamura, Takeshi, López-Casas, Pedro Pablo, Carretero, Julián, Valencia, Alfonso, Hidalgo, Manuel, Glez-Peña, Daniel, Al-Shahrour, Fátima

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A user guide for the online exploration and visualization of PCAWG data von Goldman, Mary J., Zhang, Junjun, Fonseca, Nuno A., Cortés-Ciriano, Isidro, Xiang, Qian, Craft, Brian, Piñeiro-Yáñez, Elena, O’Connor, Brian D., Bazant, Wojciech, Barrera, Elisabet, Muñoz-Pomer, Alfonso, Petryszak, Robert, Füllgrabe, Anja, Al-Shahrour, Fatima, Keays, Maria, Haussler, David, Weinstein, John N., Huber, Wolfgang, Valencia, Alfonso, Park, Peter J., Papatheodorou, Irene, Zhu, Jingchun, Ferretti, Vincent, Vazquez, Miguel

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vulcanSpot: a tool to prioritize therapeutic vulnerabilities in cancer von Perales-Patón, Javier, Di Domenico, Tomás, Fustero-Torre, Coral, Piñeiro-Yáñez, Elena, Carretero-Puche, Carlos, Tejero, Héctor, Valencia, Alfonso, Gómez-López, Gonzalo, Al-Shahrour, Fátima

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In Silico Drug Prescription for Targeting Cancer Patient Heterogeneity and Prediction of Clinical Outcome von Piñeiro-Yáñez, Elena, Jiménez-Santos, María José, Gómez-López, Gonzalo, Al-Shahrour, Fátima

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Global Transcriptomic Profiling of the Bone Marrow Stromal Microenvironment during Postnatal Development, Aging, and Inflammation von Helbling, Patrick M., Piñeiro-Yáñez, Elena, Gerosa, Rahel, Boettcher, Steffen, Al-Shahrour, Fátima, Manz, Markus G., Nombela-Arrieta, César

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Genome-Wide Transcriptomic Profiling Reveals Dynamic Functional Remodeling of the Bone Marrow Microenvironment during Postnatal Development, Aging, and Inflammation von Helbling, Patrick, Pineiro, Elena, Gerosa, Rahel, Böttcher, Steffen, Al-Shahrour, Fatima, Manz, Markus, Nombela-Arrieta, Cesar

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3058 - Genome-Wide Transcriptomic Profiling Reveals Dynamic Functional Remodeling of the Bone Marrow Microenvironment during Postnatal Development, Aging, and Inflammation von Helbling, Patrick, Pineiro, Elena, Gerosa, Rahel, Böttcher, Steffen, Al-Shahrour, Fatima, Manz, Markus, Nombela-Arrieta, Cesar

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Abstract 1548: Potent activity of CAR T cells targeting the oncofetal protein GPC2 engineered to recognize low antigen density in neuroblastoma von Heitzeneder, Sabine, Bosse, Kristopher R., Zhu, Zhongyu, Jelev, Dontcho, Dhingra, Shaurya, Majzner, Robbie, Sotillo-Pineiro, Elena, Buongervino, Samantha, Xu, Peng, Huang, Jing, Delaidelli, Alberto, Hasselblatt, Martin, Parker, Kevin, Anbunathan, Hima, Alag, Anya, Hwang, Jennifer, Huang, Min, Klysz, Dorota D., Theruvath, Johanna L., Vilches-Moure, Jose G., Satpathy, Ansuman T., Sorensen, Poul H., Dimitrov, Dimiter S., Maris, John M., Mackall, Crystal L.

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Pancreas Cancer Precision Treatment Using Avatar Mice from a Bioinformatics Perspective von Perales-Patón, Javier, Piñeiro-Yañez, Elena, Tejero, Héctor, López-Casas, Pedro P., Hidalgo, Manuel, Gómez-López, Gonzalo, Al-Shahrour, Fátima

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Type I interferon signaling pathway enhances immune-checkpoint inhibition in KRAS mutant lung tumors von Fernández-García, Fernando, Fernández-Rodríguez, Ana, Fustero-Torre, Coral, Piñeiro-Yáñez, Elena, Wang, Haiyun, Lechuga, Carmen G, Callejas, Sergio, Álvarez, Rebeca, López-García, Alejandra, Esteban-Burgos, Laura, Salmón, Marina, San Román, Marta, Guerra, Carmen, Ambrogio, Chiara, Drosten, Matthias, Santamaría, David, Al-Shahrour, Fátima, Dopazo, Ana, Barbacid, Mariano, Musteanu, Monica

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Abstract 2746: Stat3 labels a subpopulation of reactive astrocytes required for brain metastasis von Priego, Neibla, Zhu, Lucía, Monteiro, Catia, Mulders, Manon, Wasilewski, David, Bindeman, Wendy, Doglio, Laura, Martínez-Saez, Elena, Cajal, Santiago Ramón y, Fustero-Torre, Coral, Piñeiro-Yáñez, Elena, Hernández-Laín, Aurelio, Poli, Valeria, Menéndez, Javier A., Soffietti, Ricardo, Bosch-Barrera, Joaquim, Valiente, Manuel

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Efficacy of Preoperative radiation therapy for resectable rectal adenocarcinoma when combined with oral tegafur-uracil modulated with leucovorin:Results from a phase II study von ESCRIBANO UZCUDUN, Ana, FELIU BATLLE, Jaime, CALVILLO VELASCO, Jesus, SANCHEZ SANTOS, Maria Elena, DE CASTRO CARPENO, Javier, GARCIA GRANDE, Antonio, MATA JUBERIAS, Alberto, HERNANDEZ PINEIRO, Elena, MIRALLES OLIVAR, Lara, GARCIA GARCIA, Alfredo

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Telomerase activity and telomere length in primary and metastatic tumors from pediatric bone cancer patients von SOTILLO-PINEIRO, Elena, SIERRASESUMAGA, Luis, PATINO-GARCIA, Ana

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Oncogenic Rag GTPase signalling enhances B cell activation and drives follicular lymphoma sensitive to pharmacological inhibition of mTOR von Ortega-Molina, Ana, Deleyto-Seldas, Nerea, Carreras, Joaquim, Sanz, Alba, Lebrero-Fernández, Cristina, Menéndez, Camino, Vandenberg, Andrew, Fernández-Ruiz, Beatriz, Marín-Arraiza, Leyre, de la Calle Arregui, Celia, Plata-Gómez, Ana Belén, Caleiras, Eduardo, de Martino, Alba, Martínez-Martín, Nuria, Troulé, Kevin, Piñeiro-Yáñez, Elena, Nakamura, Naoya, Araf, Shamzah, Victora, Gabriel D., Okosun, Jessica, Fitzgibbon, Jude, Efeyan, Alejo

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