Prolonged exposure to FLT3 inhibitors leads to resistance via activation of parallel signaling pathways von Piloto, Obdulio, Wright, Melissa, Brown, Patrick, Kim, Kyu-Tae, Levis, Mark, Small, Donald

Volltext

FLT3 ligand causes autocrine signaling in acute myeloid leukemia cells von Zheng, Rui, Levis, Mark, Piloto, Obdulio, Brown, Patrick, Baldwin, Brenda R., Gorin, Norbert C., Beran, Miloslav, Zhu, Zhenping, Ludwig, Dale, Hicklin, Dan, Witte, Larry, Li, Yiwen, Small, Donald

Volltext

Constitutive Fms‐like tyrosine kinase 3 activation results in specific changes in gene expression in myeloid leukaemic cells von Kim, Kyu‐Tae, Baird, Kristin, Davis, Sean, Piloto, Obdulio, Levis, Mark, Li, Li, Chen, Peili, Meltzer, Paul, Small, Donald

Volltext

IMC-EB10, an anti-FLT3 monoclonal antibody, prolongs survival and reduces nonobese diabetic/severe combined immunodeficient engraftment of some acute lymphoblastic leukemia cell li... von Piloto, Obdulio, Nguyen, Bao, Huso, David, Kim, Kyu-Tae, Li, Yiwen, Witte, Larry, Hicklin, Daniel J, Brown, Patrick, Small, Donald

Volltext

Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy von Cleary, Michael L, Wang, Zhong, Smith, Kevin S, Murphy, Mark, Piloto, Obdulio, Somervaille, Tim C. P

Volltext

A new distance measure for non-identical data with application to image classification von Swaminathan, Muthukaruppan, Yadav, Pankaj Kumar, Piloto, Obdulio, Sjöblom, Tobias, Cheong, Ian

Volltext

A colorimetric chemical tongue detects and distinguishes between multiple analytes von Lim, Francis Buan Hong, Lei, Tingjun, Fernandez, Gabriella, Lopez, Nicole, Chu, Andre-Lorenz, Valiente, Allan, Nagesetti, Abhignyan, Nelson, Andy, Schmidt, Kerstin, Chang, Ta Chen, Piloto, Obdulio, Cheong, Ian

Volltext

Knock-in of an internal tandem duplication mutation into murine FLT3 confers myeloproliferative disease in a mouse model von Li, Li, Piloto, Obdulio, Nguyen, Ho Bao, Greenberg, Kathleen, Takamiya, Kogo, Racke, Frederick, Huso, David, Small, Donald

Volltext

Further activation of FLT3 mutants by FLT3 ligand von Zheng, R, Bailey, E, Nguyen, B, Yang, X, Piloto, O, Levis, M, Small, D

Volltext

Beta-Hemolytic Bacteria Selectively Trigger Liposome Lysis, Enabling Rapid and Accurate Pathogen Detection von Sum, Rongji, Swaminathan, Muthukaruppan, Rastogi, Sahil Kumar, Piloto, Obdulio, Cheong, Ian

Volltext

Next-Generation NAMPT Inhibitors Identified by Sequential High-Throughput Phenotypic Chemical and Functional Genomic Screens von Matheny, Christina J., Wei, Michael C., Bassik, Michael C., Donnelly, Alicia J., Kampmann, Martin, Iwasaki, Masayuki, Piloto, Obdulio, Solow-Cordero, David E., Bouley, Donna M., Rau, Rachel, Brown, Patrick, McManus, Michael T., Weissman, Jonathan S., Cleary, Michael L.

Volltext

Abstract LB-211: Development of a standardized drug-testing platform using human primary tumor samples von Kidd, Chris, Ebenezer, Oke, Phillips, Crystal, Lewter, Kyle, MacDonald, Allen, Adkins, Dawn, Taylor, Will, Piloto, Obdulio

Volltext

Next-Generation NAMPT Inhibitors For ALL Identified By Sequential High-Throughput Phenotypic Chemical and Functional Genomic Screens von Wei, Michael C., Matheny, Christina J., Bassik, Michael C., Donnelly, Alicia J., Kampmann, Martin, Iwasaki, Masayuki, Piloto, Obdulio, Solow-Cordero, David E., Bouley, Donna, Rau, Rachel E., Brown, Patrick, McManus, Michael T., Weissman, Jonathan S., Cleary, Michael L.

Volltext

FLT3 Ligand Is Required for Full Activation of FLT3 Mutants von Zheng, Rui, Piloto, Obdulio, Small, Donald

Volltext

FLT3/ITD expression increases expansion, survival and entry into cell cycle of human haematopoietic stem/progenitor cells von Li, Li, Piloto, Obdulio, Kim, Kyu‐Tae, Ye, Zhaohui, Nguyen, Ho Bao, Yu, Xiaobing, Levis, Mark, Cheng, Linzhao, Small, Donald

Volltext

FLT3 Inhibitor Resistant Cells Show Different Downstream Signaling Pathway Changes von Kim, Kyu-Tae, Piloto, Obdulio, Small, Donald

Volltext

FLT3 Mutant Activation Is Still Dependent on FLT3 Ligand von Zheng, Rui, Piloto, Obdulio, Small, Donald

Volltext

Inhibitory anti-FLT3 antibodies are capable of mediating antibody-dependent cell-mediated cytotoxicity and reducing engraftment of acute myelogenous leukemia blasts in nonobese dia... von PILOTO, Obdulio, LEVIS, Mark, ZHENPING ZHU, HICKLIN, Daniel J, SMALL, Donald, HUSO, David, YIWEN LI, HONGLI LI, WANG, Mei-Nai, BASSI, Rajiv, BALDERES, Paul, LUDWIG, Dale L, WITTE, Larry

Volltext

Prolonged Exposure to FLT3 Inhibitors Leads to Resistance Via Activation of Parallel Signaling Pathways von Piloto, Obdulio, Wright, Melissa, Brown, Patrick, Kim, Kyu-Tae, Levis, Mark, Small, Donald

Volltext

Knock-In of an Internal Tandem Duplication Mutation into Murine FLT3 Confers Myeloproliferative Disease in a Mouse Model von Li, Li, Piloto, Obdulio, Nguyen, Ho Bao, Greenberg, Kathleen, Racke, Frederick, Huso, David, Small, Donald

Volltext