METABOLIC SYNDROME ALTERS THE CYP450-MEDIATED METABOLISM OF ARACHIDONIC ACID TOWARDS THE DELETERIOUS VASOCONSTRICTIVE SIDE IN HUMANS von Pilote, S, Drolet, B, Simard, C

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Evaluation of Hepatic CYP2C and CYP2E Expression and Activity in Guinea Pig Models of Diet-Induced Metabolic Syndrome von Patoine, D, Pilote, S, Mercier, P, Drolet, B, Simard, C

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469 Fingolimod (Gilenya®), a New Oral Treatment for Relapsing Forms of Multiple Sclerosis, Causes Bradycardia and Prolongs the QTC Interval von Pilote, S, Patoine, D, Simard, C, Drolet, B

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384 Liver Fatty Infiltration Correlates With Decreased CYP3A Activity in a Diet-Induced Guinea Pig Model of Metabolic Syndrome von Patoine, D, Pilote, S, Drolet, B, Simard, C

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REMDESIVIR (VEKLURY) FOR TREATING COVID-19 PATIENTS: WHAT TO EXPECT FROM A CARDIAC ELECTROPHYSIOLOGICAL PERSPECTIVE von Pilote, S, Simard, C, Drolet, B

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261 Iloperidone (fanapt), a novel atypical antipsychotic, is a potent HERG blocker and delays cardiac ventricular repolarization at clinically relevant concentration von Vigneault, P, Pilote, S, Patoine, D, Simard, C, Drolet, B

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ELECLAZINE: THE HIDDEN ANTIDIABETIC POTENTIAL? von Porlier, A., Pilote, S., Simard, C., Drolet, B.

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ELECLAZINE: THE HIDDEN ANTIDIABETIC POTENTIAL? von Porlier, A., Pilote, S., Simard, C., Drolet, B.

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Role of arginine residues on the S4 segment of the Bacillus halodurans Na+ channel in voltage-sensing von Chahine, M, Pilote, S, Pouliot, V, Takami, H, Sato, C

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THE SCN5A VARIANT C683R RESULTS IN A GAIN-OF-FUNCTION OF THE CARDIAC SODIUM CURRENT (NAV1.5) WITH ADRENERGIC MODULATION von Steinberg, C., Pilote, S., Simard, C., Drolet, B.

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Blood–brain barrier and gut barrier dysfunction in chronic kidney disease with a focus on circulating biomarkers and tight junction proteins von Hernandez, Leah, Ward, Liam J., Arefin, Samsul, Ebert, Thomas, Laucyte-Cibulskiene, Agne, Heimbürger, Olof, Barany, Peter, Wennberg, Lars, Stenvinkel, Peter, Kublickiene, Karolina

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C74 ADVANCES IN TRANSLATIONAL COPD: Effects Of A Pparã And Lxr Agonists Combination Therapy On The Pulmonary Response To Cigarette Smoke von Jubinville, E, Maranda-Robitaille, M, Talbot, M, Thibault, C, Page, M, Beaulieu, M-J, Pilote, S, Aubin, S, Pare, M-E, Drolet, B, Simard, C, Morissette, M C

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Can synthetic data be a proxy for real clinical trial data? A validation study von Azizi, Zahra, Zheng, Chaoyi, Mosquera, Lucy, Pilote, Louise, El Emam, Khaled

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Angiotensin‐converting enzyme 2 and transmembrane protease serine 2 in female and male patients with end‐stage kidney disease von Arefin, Samsul, Hernandez, Leah, Ward, Liam J., Schwarz, Angelina, Barany, Peter, Stenvinkel, Peter, Kublickiene, Karolina, Pilote, Louise, Norris, Colleen M., Raparelli, Valeria, Kautzky‐Willer, Alexandra, Kublickiene, Karolina, Trinidad Herrero, Maria

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Coronary artery calcification and aortic valve calcification in patients with kidney failure: a sex-disaggregated study von Ward, Liam J, Laucyte-Cibulskiene, Agne, Hernandez, Leah, Ripsweden, Jonaz, Stenvinkel, Peter, Kublickiene, Karolina

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Sex Differences in Acute Coronary Syndrome Symptom Presentation in Young Patients von Khan, Nadia A, Daskalopoulou, Stella S, Karp, Igor, Eisenberg, Mark J, Pelletier, Roxanne, Tsadok, Meytal Avgil, Dasgupta, Kaberi, Norris, Colleen M, Pilote, Louise

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Classic antihistamines inhibit metoprololhydroxylation in vitro von Hamelin, B., Pilote, S., Turgeon, J.

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Expanding Opportunities by Adding Accessibility to Diversity, Equity, and Inclusion von Clair, Walter K, Sumner, Anne E, Lewis, Eldrin F

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Prevalence and Characterization of Subclinical Coronary Atherosclerotic Plaque with CT among Individuals with HIV: Results from the Canadian HIV and Aging Cohort Study von Boldeanu, Irina, Sadouni, Manel, Mansour, Samer, Baril, Jean-Guy, Trottier, Benoit, Soulez, Gilles, Chin, Anne S., Leipsic, Jonathon, Tremblay, Cecile, Durand, Madeleine, Chartrand-Lefebvre, Carl

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Sex-related differences in access to care among patients with premature acute coronary syndrome von Pelletier, Roxanne, Humphries, Karin H, Shimony, Avi, Bacon, Simon L, Lavoie, Kim L, Rabi, Doreen, Karp, Igor, Tsadok, Meytal Avgil, Pilote, Louise

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