Advancing the pipeline of cystic fibrosis clinical trials: a new roadmap with a global trial network perspective von Mayer-Hamblett, Nicole, Clancy, John Paul, Jain, Raksha, Donaldson, Scott H, Fajac, Isabelle, Goss, Christopher H, Polineni, Deepika, Ratjen, Felix, Quon, Bradley S, Zemanick, Edith T, Bell, Scott C, Davies, Jane C, Jain, Manu, Konstan, Michael W, Kerper, Natanya R, LaRosa, Tré, Mall, Marcus A, McKone, Edward, Pearson, Kelsie, Pilewski, Joseph M, Quittell, Lynne, Rayment, Jonathan H, Rowe, Steven M, Taylor-Cousar, Jennifer L, Retsch-Bogart, George, Downey, Damian G

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Secreted and Transmembrane Mucins Inhibit Gene Transfer with AAV4 More Efficiently than AAV5 von Walters, Robert W., Pilewski, Joseph M., Chiorini, John A., Zabner, Joseph

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Cellular and Humoral Autoreactivity in Idiopathic Pulmonary Fibrosis von Feghali-Bostwick, Carol A, Tsai, Christopher G, Valentine, Vincent G, Kantrow, Stephen, Stoner, Michael W, Pilewski, Joseph M, Gadgil, Aneal, George, M. Patricia, Gibson, Kevin F, Choi, Augustine M. K, Kaminski, Naftali, Zhang, Yingze, Duncan, Steven R

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Effect of VX-770 in Persons with Cystic Fibrosis and the G551D-CFTR Mutation von Accurso, Frank J, Rowe, Steven M, Clancy, J.P, Boyle, Michael P, Dunitz, Jordan M, Durie, Peter R, Sagel, Scott D, Hornick, Douglas B, Konstan, Michael W, Donaldson, Scott H, Moss, Richard B, Pilewski, Joseph M, Rubenstein, Ronald C, Uluer, Ahmet Z, Aitken, Moira L, Freedman, Steven D, Rose, Lynn M, Mayer-Hamblett, Nicole, Dong, Qunming, Zha, Jiuhong, Stone, Anne J, Olson, Eric R, Ordoñez, Claudia L, Campbell, Preston W, Ashlock, Melissa A, Ramsey, Bonnie W

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Autoantibodies in Patients with Chronic Obstructive Pulmonary Disease von Feghali-Bostwick, Carol A, Gadgil, Aneal S, Otterbein, Leo E, Pilewski, Joseph M, Stoner, Michael W, Csizmadia, Eva, Zhang, Yingze, Sciurba, Frank C, Duncan, Steven R

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Safety and early treatment effects of the CXCR2 antagonist SB-656933 in patients with cystic fibrosis von Moss, Richard B, Mistry, Sunil J, Konstan, Michael W, Pilewski, Joseph M, Kerem, Eitan, Tal-Singer, Ruth, Lazaar, Aili L

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A Human-Mouse Chimeric Model of Obliterative Bronchiolitis after Lung Transplantation von Xue, Jianmin, Zhu, Xuehai, George, M. Patricia, Myerburg, Michael M, Stoner, Michael W, Pilewski, Joseph W, Duncan, Steven R

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Results of a phase IIa study of VX-809, an investigational CFTR corrector compound, in subjects with cystic fibrosis homozygous for the F508del-CFTR mutation von Clancy, J P, Rowe, Steven M, Accurso, Frank J, Aitken, Moira L, Amin, Raouf S, Ashlock, Melissa A, Ballmann, Manfred, Boyle, Michael P, Bronsveld, Inez, Campbell, Preston W, De Boeck, Kris, Donaldson, Scott H, Dorkin, Henry L, Dunitz, Jordan M, Durie, Peter R, Jain, Manu, Leonard, Anissa, McCoy, Karen S, Moss, Richard B, Pilewski, Joseph M, Rosenbluth, Daniel B, Rubenstein, Ronald C, Schechter, Michael S, Botfield, Martyn, Ordoñez, Claudia L, Spencer-Green, George T, Vernillet, Laurent, Wisseh, Steve, Yen, Karl, Konstan, Michael W

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Elevated CXCL10 (IP-10) in Bronchoalveolar Lavage Fluid is Associated with Acute Cellular Rejection Following Human Lung Transplantation von Husain, Shahid, Resende, Mariangela R., Rajwans, Nimerta, Zamel, Ricardo, Pilewski, Joseph M., Crespo, Maria M, Singer, Lianne G., McCurry, Kenneth R., Kolls, Jay K., Keshavjee, Shaf, Liles, W. Conrad

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Airway Surface Liquid Volume Regulates ENaC by Altering the Serine Protease-Protease Inhibitor Balance: A MECHANISM FOR SODIUM HYPERABSORPTION IN CYSTIC FIBROSIS von Myerburg, Mike M, Butterworth, Michael B, McKenna, Erin E, Peters, Kathryn W, Frizzell, Raymond A, Kleyman, Thomas R, Pilewski, Joseph M

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Comprehensive analysis of gene expression on GOLD-2 Versus GOLD-0 smokers reveals novel genes important in the pathogenesis of COPD von Ning, Wen, Lee, Janet, Kaminski, Naftali, Feghali-Bostwick, Carol A, Watkins, Simon C, Pilewski, Joseph M, Peters, David G, Hogg, James C, Choi, Augustine M K

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Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease von Chen, Zhi-Hua, Kim, Hong Pyo, Sciurba, Frank C, Lee, Seon-Jin, Feghali-Bostwick, Carol, Stolz, Donna B, Dhir, Rajiv, Landreneau, Rodney J, Schuchert, Mathew J, Yousem, Samuel A, Nakahira, Kiichi, Pilewski, Joseph M, Lee, Janet S, Zhang, Yingze, Ryter, Stefan W, Choi, Augustine M K

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Insulin-like growth factor (IGF)-II- mediated fibrosis in pathogenic lung conditions von Garrett, Sara M, Hsu, Eileen, Thomas, Justin M, Pilewski, Joseph M, Feghali-Bostwick, Carol

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Prospective Evaluation of Coronavirus Disease 2019 (COVID-19) Vaccine Responses Across a Broad Spectrum of Immunocompromising Conditions: the COVID-19 Vaccination in the Immunocomp... von Haidar, Ghady, Agha, Mounzer, Bilderback, Andrew, Lukanski, Amy, Linstrum, Kelsey, Troyan, Rachel, Rothenberger, Scott, McMahon, Deborah K, Crandall, Melissa D, Sobolewksi, Michele D, Nathan Enick, P, Jacobs, Jana L, Collins, Kevin, Klamar-Blain, Cynthia, Macatangay, Bernard J C, Parikh, Urvi M, Heaps, Amy, Coughenour, Lindsay, Schwartz, Marc B, Dueker, Jeffrey M, Silveira, Fernanda P, Keebler, Mary E, Humar, Abhinav, Luketich, James D, Morrell, Matthew R, Pilewski, Joseph M, McDyer, John F, Pappu, Bhanu, Ferris, Robert L, Marks, Stanley M, Mahon, John, Mulvey, Katie, Hariharan, Sundaram, Updike, Glenn M, Brock, Lorraine, Edwards, Robert, Beigi, Richard H, Kip, Paula L, Wells, Alan, Minnier, Tami, Angus, Derek C, Mellors, John W

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Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis von Balch, William E, Hutt, Darren M, Herman, David, Rodrigues, Ana P C, Noel, Sabrina, Pilewski, Joseph M, Matteson, Jeanne, Hoch, Ben, Kellner, Wendy, Kelly, Jeffery W, Schmidt, Andre, Thomas, Philip J, Matsumura, Yoshihiro, Skach, William R, Gentzsch, Martina, Riordan, John R, Sorscher, Eric J, Okiyoneda, Tsukasa, Yates, John R, Lukacs, Gergely L, Frizzell, Raymond A, Manning, Gerard, Gottesfeld, Joel M

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Tezacaftor/Ivacaftor in Subjects with Cystic Fibrosis and F508del/F508del-CFTR or F508del/G551D-CFTR von Donaldson, Scott H, Pilewski, Joseph M, Griese, Matthias, Cooke, Jon, Viswanathan, Lakshmi, Tullis, Elizabeth, Davies, Jane C, Lekstrom-Himes, Julie A, Wang, Linda T

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First Characterization of the Transcriptome of Lung Fibroblasts of SSc Patients and Healthy Donors of African Ancestry von Renaud, Ludivine, Waldrep, Kristy M, da Silveira, Willian A, Pilewski, Joseph M, Feghali-Bostwick, Carol A

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Minimal Antigenic Evolution after a Decade of Norovirus GII.4 Sydney_2012 Circulation in Humans von Parra, Gabriel I, Tohma, Kentaro, Ford-Siltz, Lauren A, Eguino, Patricia, Kendra, Joseph A, Pilewski, Kelsey A, Gao, Yamei

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Routine deep vein thrombosis screening after lung transplantation: Incidence and risk factors von Jorge, Ahmed, Sanchez, Pablo G., Hayanga, J.W. Awori, Pilewski, Joseph M., Morrell, Mathew, Tuft, Marie, Ryan, John, D'Cunha, Jonathan

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A physiologically-motivated compartment-based model of the effect of inhaled hypertonic saline on mucociliary clearance and liquid transport in cystic fibrosis von Markovetz, Matthew R, Corcoran, Timothy E, Locke, Landon W, Myerburg, Michael M, Pilewski, Joseph M, Parker, Robert S

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