PROSPER: an integrated feature-based tool for predicting protease substrate cleavage sites von Song, Jiangning, Tan, Hao, Perry, Andrew J, Akutsu, Tatsuya, Webb, Geoffrey I, Whisstock, James C, Pike, Robert N

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A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis von Scally, Stephen W, Petersen, Jan, Law, Soi Cheng, Dudek, Nadine L, Nel, Hendrik J, Loh, Khai Lee, Wijeyewickrema, Lakshmi C, Eckle, Sidonia B G, van Heemst, Jurgen, Pike, Robert N, McCluskey, James, Toes, Rene E, La Gruta, Nicole L, Purcell, Anthony W, Reid, Hugh H, Thomas, Ranjeny, Rossjohn, Jamie

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Corruption of Innate Immunity by Bacterial Proteases von Potempa, Jan, Pike, Robert N.

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The X-ray Crystal Structure of Full-Length Human Plasminogen von Law, Ruby H.P., Caradoc-Davies, Tom, Cowieson, Nathan, Horvath, Anita J., Quek, Adam J., Encarnacao, Joanna Amarante, Steer, David, Cowan, Angus, Zhang, Qingwei, Lu, Bernadine G.C., Pike, Robert N., Smith, A. Ian, Coughlin, Paul B., Whisstock, James C.

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Twenty years of bioinformatics research for protease-specific substrate and cleavage site prediction: a comprehensive revisit and benchmarking of existing methods von Li, Fuyi, Wang, Yanan, Li, Chen, Marquez-Lago, Tatiana T, Leier, André, Rawlings, Neil D, Haffari, Gholamreza, Revote, Jerico, Akutsu, Tatsuya, Chou, Kuo-Chen, Purcell, Anthony W, Pike, Robert N, Webb, Geoffrey I, Ian Smith, A, Lithgow, Trevor, Daly, Roger J, Whisstock, James C, Song, Jiangning

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Protease-associated import systems are widespread in Gram-negative bacteria von Grinter, Rhys, Leung, Pok Man, Wijeyewickrema, Lakshmi C, Littler, Dene, Beckham, Simone, Pike, Robert N, Walker, Daniel, Greening, Chris, Lithgow, Trevor

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Polyphosphate is a novel cofactor for regulation of complement by a serpin, C1 inhibitor von Wijeyewickrema, Lakshmi C., Lameignere, Emilie, Hor, Lilian, Duncan, Renee C., Shiba, Toshikazu, Travers, Richard J., Kapopara, Piyushkumar R., Lei, Victor, Smith, Stephanie A., Kim, Hugh, Morrissey, James H., Pike, Robert N., Conway, Edward M.

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Molecular basis for the folding of β-helical autotransporter passenger domains von Yuan, Xiaojun, Johnson, Matthew D., Zhang, Jing, Lo, Alvin W., Schembri, Mark A., Wijeyewickrema, Lakshmi C., Pike, Robert N., Huysmans, Gerard H. M., Henderson, Ian R., Leyton, Denisse L.

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Scabies mite inactive serine proteases are potent inhibitors of the human complement lectin pathway von Reynolds, Simone L, Pike, Robert N, Mika, Angela, Blom, Anna M, Hofmann, Andreas, Wijeyewickrema, Lakshmi C, Kemp, Dave, Fischer, Katja

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Structural basis for substrate specificity of Helicobacter pylori M17 aminopeptidase von Modak, Joyanta K., Rut, Wioletta, Wijeyewickrema, Lakshmi C., Pike, Robert N., Drag, Marcin, Roujeinikova, Anna

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Keratinocyte‐specific ablation of protease‐activated receptor 2 prevents gingival inflammation and bone loss in a mouse model of periodontal disease von Francis, Nidhish, Ayodele, Babatunde A., O'Brien‐Simpson, Neil M., Birchmeier, Walter, Pike, Robert N., Pagel, Charles N., Mackie, Eleanor J.

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Common Fold Mediates Vertebrate Defense and Bacterial Attack von Rosado, Carlos J, Buckle, Ashley M, Law, Ruby H.P, Butcher, Rebecca E, Kan, Wan-Ting, Bird, Catherina H, Ung, Kheng, Browne, Kylie A, Baran, Katherine, Bashtannyk-Puhalovich, Tanya A, Faux, Noel G, Wong, Wilson, Porter, Corrine J, Pike, Robert N, Ellisdon, Andrew M, Pearce, Mary C, Bottomley, Stephen P, Emsley, Jonas, Smith, A. Ian, Rossjohn, Jamie, Hartland, Elizabeth L, Voskoboinik, Ilia, Trapani, Joseph A, Bird, Phillip I, Dunstone, Michelle A, Whisstock, James C

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Assembly of the type II secretion system such as found in Vibrio cholerae depends on the novel Pilotin AspS von Dunstan, Rhys A, Heinz, Eva, Wijeyewickrema, Lakshmi C, Pike, Robert N, Purcell, Anthony W, Evans, Timothy J, Praszkier, Judyta, Robins-Browne, Roy M, Strugnell, Richard A, Korotkov, Konstantin V, Lithgow, Trevor

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Total Synthesis of Homogeneous Variants of Hirudin P6: A Post-Translationally Modified Anti-Thrombotic Leech-Derived Protein von Hsieh, Yves S. Y., Wijeyewickrema, Lakshmi C., Wilkinson, Brendan L., Pike, Robert N., Payne, Richard J.

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Cathepsin B proteases of flukes: the key to facilitating parasite control? von Smooker, Peter M, Jayaraj, Rama, Pike, Robert N, Spithill, Terry W

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GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop von Pike, Robert N, Rosado, Carlos J, Fenalti, Gustavo, Mahmood, Khalid, El-Kabbani, Ossama, Wilce, Matthew, Tuck, Kellie, Rossjohn, Jamie, Mackay, Ian R, Whisstock, James C, Schmidberger, Jason, Rowley, Merrill J, Banga, J Paul, Faux, Noel G, Smith, A Ian, Hampe, Christiane S, Langendorf, Christopher, Law, Ruby H P, Buckle, Ashley M

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Molecular Interactions Required for Activation of Complement Component C2 Include Exosites Located on the Serine Protease Domain of C1s and Mannose-Binding Lectin Associated Protea... von Hor, Lilian, Pan, Jing, Pike, Robert N, Wijeyewickrema, Lakshmi C

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PROSPERous: high-throughput prediction of substrate cleavage sites for 90 proteases with improved accuracy von Song, Jiangning, Li, Fuyi, Leier, André, Marquez-Lago, Tatiana T, Akutsu, Tatsuya, Haffari, Gholamreza, Chou, Kuo-Chen, Webb, Geoffrey I, Pike, Robert N

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The subtilisin-like protease AprV2 is required for virulence and uses a novel disulphide-tethered exosite to bind substrates von Kennan, Ruth M, Wong, Wilson, Dhungyel, Om P, Han, Xiaoyan, Wong, David, Parker, Dane, Rosado, Carlos J, Law, Ruby H P, McGowan, Sheena, Reeve, Shane B, Levina, Vita, Powers, Glenn A, Pike, Robert N, Bottomley, Stephen P, Smith, A Ian, Marsh, Ian, Whittington, Richard J, Whisstock, James C, Porter, Corrine J, Rood, Julian I

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An Immune Response Directed to Proteinase and Adhesin Functional Epitopes Protects against Porphyromonas gingivalis-Induced Periodontal Bone Loss von O'Brien-Simpson, Neil M, Pathirana, Rishi D, Paolini, Rita A, Chen, Yu-Yen, Veith, Paul D, Tam, Vivian, Ally, Nafisa, Pike, Robert N, Reynolds, Eric C

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