Structure of the CaMKIIδ/Calmodulin Complex Reveals the Molecular Mechanism of CaMKII Kinase Activation von Rellos, Peter, Pike, Ashley C.W, Niesen, Frank H, Salah, Eidarus, Lee, Wen Hwa, von Delft, Frank, Knapp, Stefan

Volltext

A lower X-gate in TASK channels traps inhibitors within the vestibule von Rödström, Karin E. J., Kiper, Aytuğ K., Zhang, Wei, Rinné, Susanne, Pike, Ashley C. W., Goldstein, Matthias, Conrad, Linus J., Delbeck, Martina, Hahn, Michael G., Meier, Heinrich, Platzk, Magdalena, Quigley, Andrew, Speedman, David, Shrestha, Leela, Mukhopadhyay, Shubhashish M. M., Burgess-Brown, Nicola A., Tucker, Stephen J., Müller, Thomas, Decher, Niels, Carpenter, Elisabeth P.

Volltext

Three-dimensional Structure and Enzymatic Function of Proapoptotic Human p53-inducible Quinone Oxidoreductase PIG3 von Porté, Sergio, Valencia, Eva, Yakovtseva, Evgenia A., Borràs, Emma, Shafqat, Naeem, Debreczeny, Judit É., Pike, Ashley C.W., Oppermann, Udo, Farrés, Jaume, Fita, Ignacio, Parés, Xavier

Volltext

Structure of the human RECQ1 helicase reveals a putative strand-separation pin von Pike, Ashley C.W, Shrestha, Binesh, Popuri, Venkateswarlu, Burgess-Brown, Nicola, Muzzolini, Laura, Costantini, Silvia, Vindigni, Alessandro, Gileadi, Opher

Volltext

Structural Basis for c-KIT Inhibition by the Suppressor of Cytokine Signaling 6 (SOCS6) Ubiquitin Ligase von Zadjali, Fahad, Pike, Ashley C.W., Vesterlund, Mattias, Sun, Jianmin, Wu, Chenggang, Li, Shawn S.C., Rönnstrand, Lars, Knapp, Stefan, Bullock, Alex N., Flores-Morales, Amilcar

Volltext

Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist von Pike, Ashley C. W., Brzozowski, Andrzej M., Hubbard, Roderick E., Bonn, Tomas, Thorsell, Ann-Gerd, Engström, Owe, Ljunggren, Jan, Gustafsson, Jan-Åke, Carlquist, Mats

Volltext

Structural comparison of human mammalian ste20-like kinases von Record, Christopher J, Chaikuad, Apirat, Rellos, Peter, Das, Sanjan, Pike, Ashley C W, Fedorov, Oleg, Marsden, Brian D, Knapp, Stefan, Lee, Wen Hwa

Volltext

Structure of dystrophia myotonica protein kinase von Elkins, Jonathan M., Amos, Ann, Niesen, Frank H., Pike, Ashley C.W., Fedorov, Oleg, Knapp, Stefan

Volltext

Structural Insights into Corepressor Recognition by Antagonist-bound Estrogen Receptors von Heldring, Nina, Pawson, Tanya, McDonnell, Donald, Treuter, Eckardt, Gustafsson, Jan-Åke, Pike, Ashley C.W.

Volltext

Outcomes of renal replacement therapy in the critically ill with COVID-19 von Burke, E., Haber, E., Pike, C.W., Sonti, R.

Volltext

Outcomes of renal replacement therapy in the critically ill with COVID-19 von Burke, E., Haber, E., Pike, C.W., Sonti, R.

Volltext

Novel FXXFF and FXXMF Motifs in Androgen Receptor Cofactors Mediate High Affinity and Specific Interactions with the Ligand-binding Domain von van de Wijngaart, Dennis J., van Royen, Martin E., Hersmus, Remko, Pike, Ashley C.W., Houtsmuller, Adriaan B., Jenster, Guido, Trapman, Jan, Dubbink, Hendrikus J.

Volltext

A structural biologist's view of the oestrogen receptor von Pike, Ashley C.W, Brzozowski, Andrzej M, Hubbard, Roderick E

Volltext

K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac von Dong, Yin Yao, Pike, Ashley C. W., Mackenzie, Alexandra, McClenaghan, Conor, Aryal, Prafulla, Dong, Liang, Quigley, Andrew, Grieben, Mariana, Goubin, Solenne, Mukhopadhyay, Shubhashish, Ruda, Gian Filippo, Clausen, Michael V., Cao, Lishuang, Brennan, Paul E., Burgess-Brown, Nicola A., Sansom, Mark S. P., Tucker, Stephen J., Carpenter, Elisabeth P.

Volltext

A pharmacological master key mechanism that unlocks the selectivity filter gate in K⁺ channels von Schewe, Marcus, Sun, Han, Mert, Ümit, Mackenzie, Alexandra, Pike, Ashley C. W., Schulz, Friederike, Constantin, Cristina, Vowinkel, Kirsty S., Conrad, Linus J., Kiper, Aytug K., Gonzalez, Wendy, Musinszki, Marianne, Tegtmeier, Marie, Pryde, David C., Belabed, Hassane, Nazare, Marc, de Groot, Bert L., Decher, Niels, Fakler, Bernd, Carpenter, Elisabeth P., Tucker, Stephen J., Baukrowitz, Thomas

Volltext

Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2) von Grieben, Mariana, Pike, Ashley C W, Shintre, Chitra A, Venturi, Elisa, El-Ajouz, Sam, Tessitore, Annamaria, Shrestha, Leela, Mukhopadhyay, Shubhashish, Mahajan, Pravin, Chalk, Rod, Burgess-Brown, Nicola A, Sitsapesan, Rebecca, Huiskonen, Juha T, Carpenter, Elisabeth P

Volltext

Outcomes of renal replacement therapy in the critically ill with COVID-19 von Burke, E, Haber, E, Pike, C W, Sonti, R

Volltext

Structural Basis for Cul3 Protein Assembly with the BTB-Kelch Family of E3 Ubiquitin Ligases von Canning, Peter, Cooper, Christopher D.O., Krojer, Tobias, Murray, James W., Pike, Ashley C.W., Chaikuad, Apirat, Keates, Tracy, Thangaratnarajah, Chancievan, Hojzan, Viktorija, Marsden, Brian D., Gileadi, Opher, Knapp, Stefan, von Delft, Frank, Bullock, Alex N.

Volltext

The structural basis of fatty acid elongation by the ELOVL elongases von Nie, Laiyin, Pascoa, Tomas C., Pike, Ashley C. W., Bushell, Simon R., Quigley, Andrew, Ruda, Gian Filippo, Chu, Amy, Cole, Victoria, Speedman, David, Moreira, Tiago, Shrestha, Leela, Mukhopadhyay, Shubhashish M. M., Burgess-Brown, Nicola A., Love, James D., Brennan, Paul E., Carpenter, Elisabeth P.

Volltext

The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K von Bushell, Simon R., Pike, Ashley C. W., Falzone, Maria E., Rorsman, Nils J. G., Ta, Chau M., Corey, Robin A., Newport, Thomas D., Christianson, John C., Scofano, Lara F., Shintre, Chitra A., Tessitore, Annamaria, Chu, Amy, Wang, Qinrui, Shrestha, Leela, Mukhopadhyay, Shubhashish M. M., Love, James D., Burgess-Brown, Nicola A., Sitsapesan, Rebecca, Stansfeld, Phillip J., Huiskonen, Juha T., Tammaro, Paolo, Accardi, Alessio, Carpenter, Elisabeth P.

Volltext