Immunotherapies for hepatocellular carcinoma von Llovet, Josep M., Castet, Florian, Heikenwalder, Mathias, Maini, Mala K., Mazzaferro, Vincenzo, Pinato, David J., Pikarsky, Eli, Zhu, Andrew X., Finn, Richard S.

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Hepatocellular carcinoma von Llovet, Josep M., Kelley, Robin Kate, Villanueva, Augusto, Singal, Amit G., Pikarsky, Eli, Roayaie, Sasan, Lencioni, Riccardo, Koike, Kazuhiko, Zucman-Rossi, Jessica, Finn, Richard S.

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Adult Hepatocytes Are Generated by Self-Duplication Rather than Stem Cell Differentiation von Yanger, Kilangsungla, Knigin, David, Zong, Yiwei, Maggs, Lara, Gu, Guoqiang, Akiyama, Haruhiko, Pikarsky, Eli, Stanger, Ben Z.

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Long Noncoding RNA MALAT1 Promotes Hepatocellular Carcinoma Development by SRSF1 Upregulation and mTOR Activation von Malakar, Pushkar, Shilo, Asaf, Mogilevsky, Adi, Stein, Ilan, Pikarsky, Eli, Nevo, Yuval, Benyamini, Hadar, Elgavish, Sharona, Zong, Xinying, Prasanth, Kannanganattu V, Karni, Rotem

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Predicting and affecting response to cancer therapy based on pathway-level biomarkers von Ben-Hamo, Rotem, Jacob Berger, Adi, Gavert, Nancy, Miller, Mendy, Pines, Guy, Oren, Roni, Pikarsky, Eli, Benes, Cyril H., Neuman, Tzahi, Zwang, Yaara, Efroni, Sol, Getz, Gad, Straussman, Ravid

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A single cell atlas of the human liver tumor microenvironment von Massalha, Hassan, Bahar Halpern, Keren, Abu‐Gazala, Samir, Jana, Tamar, Massasa, Efi E, Moor, Andreas E, Buchauer, Lisa, Rozenberg, Milena, Pikarsky, Eli, Amit, Ido, Zamir, Gideon, Itzkovitz, Shalev

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The microbiota programs DNA methylation to control intestinal homeostasis and inflammation von Ansari, Ihab, Raddatz, Günter, Gutekunst, Julian, Ridnik, Meshi, Cohen, Daphne, Abu-Remaileh, Monther, Tuganbaev, Timur, Shapiro, Hagit, Pikarsky, Eli, Elinav, Eran, Lyko, Frank, Bergman, Yehudit

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Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma von Finkin, Shlomi, Yuan, Detian, Stein, Ilan, Taniguchi, Koji, Weber, Achim, Unger, Kristian, Browning, Jeffrey L, Goossens, Nicolas, Nakagawa, Shigeki, Gunasekaran, Ganesh, Schwartz, Myron E, Kobayashi, Masahiro, Kumada, Hiromitsu, Berger, Michael, Pappo, Orit, Rajewsky, Klaus, Hoshida, Yujin, Karin, Michael, Heikenwalder, Mathias, Ben-Neriah, Yinon, Pikarsky, Eli

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miRNA-132 induces hepatic steatosis and hyperlipidaemia by synergistic multitarget suppression von Hanin, Geula, Yayon, Nadav, Tzur, Yonat, Haviv, Rotem, Bennett, Estelle R, Udi, Shiran, Krishnamoorthy, Yoganathan R, Kotsiliti, Eleni, Zangen, Rivka, Efron, Ben, Tam, Joseph, Pappo, Orit, Shteyer, Eyal, Pikarsky, Eli, Heikenwalder, Mathias, Greenberg, David S, Soreq, Hermona

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Splicing factor hnRNP A2 activates the Ras-MAPK-ERK pathway by controlling A-Raf splicing in hepatocellular carcinoma development von Shilo, Asaf, Ben Hur, Vered, Denichenko, Polina, Stein, Ilan, Pikarsky, Eli, Rauch, Jens, Kolch, Walter, Zender, Lars, Karni, Rotem

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A Senescence-Inflammatory Switch from Cancer-Inhibitory to Cancer-Promoting Mechanism von Pribluda, Ariel, Elyada, Ela, Wiener, Zoltan, Hamza, Haya, Goldstein, Robert E., Biton, Moshe, Burstain, Ido, Morgenstern, Yael, Brachya, Guy, Billauer, Hana, Biton, Sharon, Snir-Alkalay, Irit, Vucic, Domagoj, Schlereth, Katharina, Mernberger, Marco, Stiewe, Thorsten, Oren, Moshe, Alitalo, Kari, Pikarsky, Eli, Ben-Neriah, Yinon

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Postnatal DNA demethylation and its role in tissue maturation von Reizel, Yitzhak, Sabag, Ofra, Skversky, Yael, Spiro, Adam, Steinberg, Benjamin, Bernstein, Diana, Wang, Amber, Kieckhaefer, Julia, Li, Catherine, Pikarsky, Eli, Levin-Klein, Rena, Goren, Alon, Rajewsky, Klaus, Kaestner, Klaus H., Cedar, Howard

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TET2 and TET3 loss disrupts small intestine differentiation and homeostasis von Ansari, Ihab, Solé-Boldo, Llorenç, Ridnik, Meshi, Gutekunst, Julian, Gilliam, Oliver, Korshko, Maria, Liwinski, Timur, Jickeli, Birgit, Weinberg-Corem, Noa, Shoshkes-Carmel, Michal, Pikarsky, Eli, Elinav, Eran, Lyko, Frank, Bergman, Yehudit

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RNF20 Links Histone H2B Ubiquitylation with Inflammation and Inflammation-Associated Cancer von Tarcic, Ohad, Pateras, Ioannis S., Cooks, Tomer, Shema, Efrat, Kanterman, Julia, Ashkenazi, Hadas, Boocholez, Hana, Hubert, Ayala, Rotkopf, Ron, Baniyash, Michal, Pikarsky, Eli, Gorgoulis, Vassilis G., Oren, Moshe

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Human and mouse VEGFA-amplified hepatocellular carcinomas are highly sensitive to sorafenib treatment von Horwitz, Elad, Stein, Ilan, Andreozzi, Mariacarla, Nemeth, Julia, Shoham, Avivit, Pappo, Orit, Schweitzer, Nora, Tornillo, Luigi, Kanarek, Naama, Quagliata, Luca, Zreik, Farid, Porat, Rinnat M, Finkelstein, Rutie, Reuter, Hendrik, Koschny, Ronald, Ganten, Tom, Mogler, Carolin, Shibolet, Oren, Hess, Jochen, Breuhahn, Kai, Grunewald, Myriam, Schirmacher, Peter, Vogel, Arndt, Terracciano, Luigi, Angel, Peter, Ben-Neriah, Yinon, Pikarsky, Eli

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RNF20 and histone H2B ubiquitylation exert opposing effects in Basal-Like versus luminal breast cancer von Tarcic, Ohad, Granit, Roy Z, Pateras, Ioannis S, Masury, Hadas, Maly, Bella, Zwang, Yaara, Yarden, Yosef, Gorgoulis, Vassilis G, Pikarsky, Eli, Ben-Porath, Ittai, Oren, Moshe

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PI3K/AKT/mTOR‐dependent stabilization of oncogenic far‐upstream element binding proteins in hepatocellular carcinoma cells von Samarin, Jana, Laketa, Vibor, Malz, Mona, Roessler, Stephanie, Stein, Ilan, Horwitz, Elad, Singer, Stephan, Dimou, Eleni, Cigliano, Antonio, Bissinger, Michaela, Falk, Christine Susanne, Chen, Xin, Dooley, Steven, Pikarsky, Eli, Calvisi, Diego Francesco, Schultz, Carsten, Schirmacher, Peter, Breuhahn, Kai

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VICKZ1 enhances tumor progression and metastasis in lung adenocarcinomas in mice von Rosenfeld, Yifat Bar-Zakay, Krumbein, Miriam, Yeffet, Avner, Schiffmann, Nathan, Mishalian, Inbal, Pikarsky, Eli, Oberman, Froma, Fridlender, Zvi, Yisraeli, Joel K.

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The NF-ĸB p50 subunit generated by KPC1-mediated ubiquitination and limited proteasomal processing, suppresses tumor growth von Kravtsova-Ivantsiv, Yelena, Goldhirsh, Gilad, Tomuleasa, Ciprian, Pikarsky, Eli, Ciechanover, Aaron

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Chronic expression of p16INK4a in the epidermis induces Wnt-mediated hyperplasia and promotes tumor initiation von Azazmeh, Narmen, Assouline, Benjamin, Winter, Eitan, Ruppo, Shmuel, Nevo, Yuval, Maly, Alexander, Meir, Karen, Witkiewicz, Agnieszka K., Cohen, Jonathan, Rizou, Sophia V., Pikarsky, Eli, Luxenburg, Chen, Gorgoulis, Vassilis G., Ben-Porath, Ittai

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