In silico agent-based modeling approach to characterize multiple in vitro tuberculosis infection models von Petrucciani, Alexa, Hoerter, Alexis, Kotze, Leigh, Du Plessis, Nelita, Pienaar, Elsje

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Agent-based model predicts that layered structure and 3D movement work synergistically to reduce bacterial load in 3D in vitro models of tuberculosis granuloma von Petrucciani, Alexa, Hoerter, Alexis, Kotze, Leigh, Du Plessis, Nelita, Pienaar, Elsje

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Mathematical modeling indicates that regulatory inhibition of CD8+ T cell cytotoxicity can limit efficacy of IL-15 immunotherapy in cases of high pre-treatment SIV viral load von Cody, Jonathan W., Ellis-Connell, Amy L., O’Connor, Shelby L., Pienaar, Elsje

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Multifidelity Analysis for Predicting Rare Events in Stochastic Computational Models of Complex Biological Systems von Pienaar, Elsje

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Emergence and selection of isoniazid and rifampin resistance in tuberculosis granulomas von Pienaar, Elsje, Linderman, Jennifer J, Kirschner, Denise E

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Systems biology approaches to investigate the role of granulomas in TB-HIV coinfection von Hoerter, Alexis, Arnett, Eusondia, Schlesinger, Larry S, Pienaar, Elsje

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Comparing efficacies of moxifloxacin, levofloxacin and gatifloxacin in tuberculosis granulomas using a multi-scale systems pharmacology approach von Pienaar, Elsje, Sarathy, Jansy, Prideaux, Brendan, Dietzold, Jillian, Dartois, Véronique, Kirschner, Denise E, Linderman, Jennifer J

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Impact of Ebola virus nucleoprotein on VP40 virus-like particle production: a computational approach von Liu, Xiao, Stahelin, Robert V., Pienaar, Elsje

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Deletion of TGF-β1 Increases Bacterial Clearance by Cytotoxic T Cells in a Tuberculosis Granuloma Model von Warsinske, Hayley C, Pienaar, Elsje, Linderman, Jennifer J, Mattila, Joshua T, Kirschner, Denise E

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Evaluation of fendiline treatment in VP40 system with nucleation-elongation process: a computational model of Ebola virus matrix protein assembly von Liu, Xiao, Husby, Monica, Stahelin, Robert V, Pienaar, Elsje

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Replication rates of Mycobacterium tuberculosis in human macrophages do not correlate with mycobacterial antibiotic susceptibility von Raffetseder, Johanna, Pienaar, Elsje, Blomgran, Robert, Eklund, Daniel, Patcha Brodin, Veronika, Andersson, Henrik, Welin, Amanda, Lerm, Maria

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Mathematical modeling of N-803 treatment in SIV-infected non-human primates von Cody, Jonathan W., Ellis-Connell, Amy L., O'Connor, Shelby L., Pienaar, Elsje

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Ribosome kinetics and aa-tRNA competition determine rate and fidelity of peptide synthesis von Fluitt, Aaron, Pienaar, Elsje, Viljoen, Hendrik

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Scaffolded team-based computational modeling and simulation projects for promoting representational competence and regulatory skills von Magana, Alejandra J., Arigye, Joreen, Udosen, Abasiafak, Lyon, Joseph A., Joshi, Parth, Pienaar, Elsje

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Microglial roles in Alzheimer's disease: An agent‐based model to elucidate microglial spatiotemporal response to beta‐amyloid von Weathered, Catherine, Bardehle, Sophia, Yoon, Choya, Kumar, Niyanta, Leyns, Cheryl E. G., Kennedy, Matthew E., Bloomingdale, Peter, Pienaar, Elsje

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Integrating Non-human Primate, Human, and Mathematical Studies to Determine the Influence of BCG Timing on H56 Vaccine Outcomes von Joslyn, Louis R, Pienaar, Elsje, DiFazio, Robert M, Suliman, Sara, Kagina, Benjamin M, Flynn, JoAnne L, Scriba, Thomas J, Linderman, Jennifer J, Kirschner, Denise E

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Reduced macrophage killing of M. avium drives infection risk in post-menopausal patients von Weathered, Catherine, Wei, Ning, Pienaar, Elsje

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Efficiency of the polymerase chain reaction von Booth, Christine S., Pienaar, Elsje, Termaat, Joel R., Whitney, Scott E., Louw, Tobias M., Viljoen, Hendrik J.

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The Role of Biofilms, Bacterial Phenotypes, and Innate Immune Response in Mycobacterium avium Colonization to Infection von Weathered, Catherine, Pennington, Kelly, Escalante, Patricio, Pienaar, Elsje

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In Vitro Granuloma Models of Tuberculosis: Potential and Challenges von Elkington, Paul, Lerm, Maria, Kapoor, Nidhi, Mahon, Robert, Pienaar, Elsje, Huh, Dongeun, Kaushal, Deepak, Schlesinger, Larry S

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