Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes von Clarke, Matthew, Mackay, Alan, Ismer, Britta, Pickles, Jessica C., Tatevossian, Ruth G., Newman, Scott, Bale, Tejus A., Stoler, Iris, Izquierdo, Elisa, Temelso, Sara, Carvalho, Diana M., Molinari, Valeria, Burford, Anna, Howell, Louise, Virasami, Alex, Fairchild, Amy R., Avery, Aimee, Chalker, Jane, Kristiansen, Mark, Haupfear, Kelly, Dalton, James D., Orisme, Wilda, Wen, Ji, Hubank, Michael, Kurian, Kathreena M., Rowe, Catherine, Maybury, Mellissa, Crosier, Stephen, Knipstein, Jeffrey, Schueller, Ulrich, Kordes, Uwe, Kram, David E., Snuderl, Matija, Bridges, Leslie, Martin, Andrew J., Doey, Lawrence J., Al-Sarraj, Safa, Chandler, Christopher, Zebian, Bassel, Cairns, Claire, Natrajan, Rachael, Boult, Jessica K. R., Robinson, Simon P., Sill, Martin, Dunkel, Ira J., Gilheeney, Stephen W., Rosenblum, Marc K., Hughes, Debbie, Proszek, Paula Z., Macdonald, Tobey J., Preusser, Matthias, Haberler, Christine, Slavc, Irene, Packer, Roger, Ng, Ho-Keung, Caspi, Shani, Popovi, Mara, Kotnik, Barbara Faganel, Wood, Matthew D., Baird, Lissa, Davare, Monika Ashok, Solomon, David A., Olsen, Thale Kristin, Brandal, Petter, Farrell, Michael, Cryan, Jane B., Capra, Michael, Karremann, Michael, Schittenhelm, Jens, Schuhmann, Martin U., Ebinger, Martin, Dinjens, Winand N. M., Kerl, Kornelius, Hettmer, Simone, Pietsch, Torsten, Andreiuolo, Felipe, Driever, Pablo Hernaiz, Korshunov, Andrey, Hiddingh, Lotte, Worst, Barbara C., Sturm, Dominik, Zuckermann, Marc, Witt, Olaf, Bloom, Tabitha, Mitchell, Clare, Miele, Evelina, Colafati, Giovanna Stefania, Diomedi-Camassei, Francesca, Bailey, Simon, Moore, Andrew S., Hassall, Timothy E. G., Lowis, Stephen P., Tsoli, Maria, Cowley, Mark J., Ziegler, David S., Karajannis, Matthias A., Aquilina, Kristian, Hargrave, Darren R., Carceller, Fernando, Marshall, Lynley

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Methylation-based algorithms for diagnosis: experience from neuro-oncology von Pickles, JC, Stone, TJ, Jacques, TS

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Emergence and maintenance of actionable genetic drivers at medulloblastoma relapse von Richardson, S, Hill, RM, Kui, C, Lindsey, JC, Grabovksa, Y, Keeling, C, Pease, L, Bashton, M, Crosier, S, Vinci, M, André, N, Figarella-Branger, D, Hansford, JR, Lastowska, M, Zakrzewski, K, Jorgensen, M, Pickles, JC, Taylor, MD, Pfister, SM, Wharton, SB, Pizer, B, Michalski, A, Joshi, A, Jacques, TS, Hicks, D, Schwalbe, EC, Williamson, D, Ramaswamy, V, Bailey, S, Clifford, SC

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A rare case of paediatric astroblastoma with concomitant MN1-GTSE1 and EWSR1-PATZ1 gene fusions altering management von Chadda, KR, Holland, K, Scoffings, D, Dean, A, Pickles, JC, Behjati, S, Jacques, TS, Trotman, J, Tarpey, P, Allinson, K, Murray, MJ, Genomics England Research Consortium

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Identifying cellular signalling molecules in developmental disorders of the brain: Evidence from focal cortical dysplasia and tuberous sclerosis von Li, Y-F, Scerif, F, Picker, SR, Stone, TJ, Pickles, JC, Moulding, DA, Avery, A, Virasami, A, Fairchild, AR, Tisdall, M, Harkness, W, Cross, JH, Hargrave, D, Guillemot, F, Paine, S, Yasin, SA, Jacques, TS

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CNS embryonal tumours: WHO 2016 and beyond von Pickles, JC, Hawkins, C, Pietsch, T, Jacques, TS

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A case series of Diffuse Glioneuronal Tumours with Oligodendroglioma-like features and Nuclear Clusters (DGONC) von Pickles, JC, Mankad, K, Aizpurua, M, Paine, SM, Bridges, LR, Carceller, F, Szychot, E, Walker, M, Fairchild, AR, Mistry, T, Ogunbiyi, O, Rolland, A, Stone, TJ, Dryden, C, Addy, D, Garimberti, E, Chalker, J, Sahm, F, Jones, DT, Hargrave, D, Jacques, TS

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Pediatric pan-central nervous system tumor analysis of immune-cell infiltration identifies correlates of antitumor immunity von Grabovska, Y, Mackay, A, O'Hare, P, Crosier, S, Finetti, M, Schwalbe, EC, Pickles, JC, Fairchild, AR, Avery, A, Cockle, J, Hill, R, Lindsey, J, Hicks, D, Kristiansen, M, Chalker, J, Anderson, J, Hargrave, D, Jacques, TS, Straathof, K, Bailey, S, Jones, C, Clifford, SC, Williamson, D

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Early Wound Site Seeding in a Patient with Central Nervous System High-Grade Neuroepithelial Tumor with BCOR Alteration von Kirkman, MA, Pickles, JC, Fairchild, AR, Avery, A, Pietsch, T, Jacques, TS, Aquilina, K

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Therapeutic implications of improved molecular diagnostics for rare CNS-embryonal tumor entities: results of an international, retrospective study von von Hoff, K, Haberler, C, Schmitt-Hoffner, F, Schepke, E, de Rojas, T, Jacobs, S, Zapotocky, M, Sumerauer, D, Perek-Polnik, M, Dufour, C, van Vuurden, D, Slavc, I, Gojo, J, Pickles, JC, Gerber, NU, Massimino, M, Gil-da-Costa, MJ, Garami, M, Kumirova, E, Sehested, A, Scheie, D, Cruz, O, Moreno, L, Cho, J, Zeller, B, Bovenschen, N, Grotzer, M, Alderete, D, Snuderl, M, Zheludkova, O, Golanov, A, Okonechnikov, K, Mynarek, M, Juhnke, BO, Rutkowski, S, Schüller, U, Pizer, B, Zezschwitz, BV, Kwiecien, R, Wechsung, M, Konietschke, F, Hwang, EI, Sturm, D, Pfister, SM, von Deimling, A, Rushing, EJ, Ryzhova, M, Hauser, P, Łastowska, M, Wesseling, P, Giangaspero, F, Hawkins, C, Figarella-Branger, D, Eberhart, C, Burger, P, Gessi, M, Korshunov, A, Jacques, TS, Capper, D, Pietsch, T, Kool, M

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Clinical outcomes, Kadish-INSICA staging and therapeutic targeting of somatostatin receptor 2 in olfactory neuroblastoma von Lechner, M, Takahashi, Y, Turri-Zanoni, M, Liu, J, Counsell, N, Kaur, RP, Zhao, T, Ramanathan, M, Schartinger, VH, Emanuel, O, Helman, S, Varghese, J, Dudas, J, Riechelmann, H, Sprung, S, Haybaeck, J, Howard, D, Engel, NW, Stewart, S, Brooks, L, Pickles, JC, Jacques, TS, Fenton, TR, Williams, L, Vaz, FM, O'Flynn, P, Stimpson, P, Wang, S, Hannan, SA, Unadkat, S, Hughes, J, Dwivedi, R, Forde, CT, Randhawa, P, Gane, S, Joseph, J, Andrews, PJ, Royle, G, Franchi, A, Maragliano, R, Battocchio, S, Bewicke-Copley, H, Pipinikas, C, Webster, A, Thirlwell, C, Ho, D, Teschendorff, A, Zhu, T, Steele, CD, Pillay, N, Vanhaesebroeck, B, Mohyeldin, A, Fernandez-Miranda, J, Park, KW, Le, Q-T, West, RB, Saade, R, Manes, RP, Omay, SB, Vining, EM, Judson, BL, Yarbrough, WG, Sansovini, M, Silvia, N, Grassi, I, Bongiovanni, A, Capper, D, Schüller, U, Thavaraj, S, Sandison, A, Surda, P, Hopkins, C, Ferrari, M, Mattavelli, D, Rampinelli, V, Facchetti, F, Nicolai, P, Bossi, P, Henriquez, OA, Magliocca, K, Solares, CA, Wise, SK, Llorente, JL, Patel, ZM, Nayak, JV, Hwang, PH, Lacy, PD, Woods, R, O'Neill, JP, Jay, A, Carnell, D, Forster, MD, Ishii, M, London, NR, Bell, DM, Gallia, GL, Castelnuovo, P, Severi, S, Lund, VJ, Hanna, EY

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DNA methylation-based profiling for paediatric CNS tumour diagnosis and treatment: a population-based study von Pickles, JC, Fairchild, AR, Stone, TJ, Brownlee, L, Merve, A, Yasin, SA, Avery, A, Ahmed, SW, Ogunbiyi, O, Gonzalez Zapata, J, Peary, AF, Edwards, M, Wilkhu, L, Dryden, C, Ladon, D, Kristiansen, M, Rowe, C, Kurian, KM, Nicoll, JAR, Mitchell, C, Bloom, T, Hilton, DA, Al-Sarraj, S, Doey, L, Johns, PN, Bridges, LR, Chakrabarty, A, Ismail, A, Rathi, N, Syed, K, Lammie, GA, Limback-Stanic, C, Smith, C, Torgersen, A, Rae, F, Hill, RM, Clifford, SC, Grabovska, Y, Williamson, D, Clarke, M, Jones, C, Capper, D, Sill, M, von Deimling, A, Pfister, SM, Jones, DTW, Hargrave, D, Chalker, J, Jacques, TS

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Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes von Clarke, M, Mackay, A, Ismer, B, Pickles, JC, Bale, TA, Stoler, I, Izquierdo, E, Temelso, S, Carvalho, DM, Molinari, V, Burford, A, Howell, L, Virasami, A, Fairchild, AR, Avery, A, Chalker, J, Kristiansen, M, Haupfear, K, Dalton, JD, Orisme, W, Hubank, M, Kurian, KM, Rowe, C, Maybury, M, Crosier, S, Knipstein, J, Schuller, U, Kordes, U, Snuderl, M, Bridges, L, Martin, AJ, Doey, LJ, Chandler, C, Zebian, B, Cairns, C, Natrajan, R, Boult, JK, Robinson, SP, Sill, M, Dunkel, IJ, Gilheeney, SW, Rosenblum, MK, Hughes, D, Proszek, PZ, MacDonald, TJ, Preusser, M, Haberler, C, Slavc, I, Packer, R, Ng, H-K, Caspi, S, Popovic, M, Faganel Kotnik, B, Wood, MD, Davare, MA, Solomon, DA, Olsen, TK, Brandal, P, Farrell, M, Capra, M, Karremann, M, Schittenhelm, J, Schuhmann, MU, Ebinger, M, Kerl, K, Hettmer, S, Pietsch, T, Andreiuolo, F, Driever, PH, Korshunov, A, Hiddingh, L, Worst, BC, Sturm, D, Zuckermann, M, Mitchell, C, Miele, E, Colafati, GS, Diomedi-Camassei, F, Bailey, S, Moore, AS, Hassall, TE, Lowis, SP, Tsoli, M, Cowley, MJ, Ziegler, DS, Karajannis, MA, Aquilina, K, Hargrave, DR, Carceller, F, Marshall, LV, von Deimling, A, Kramm, CM, Pfister, SM, Sahm, F, Baker, SJ, Carai, A, Capper, D, Popov, S, Jacques, TS, Jones, C

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A mechanistic evaluation of the Syrian hamster embryo cell transformation assay (pH 6.7) and molecular events leading to senescence bypass in SHE cells von Pickles, JC, Pant, K, McGinty, LA, Yasaei, H, Roberts, T, Scott, AD, Newbold, RF

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Influenza M2 envelope protein augments avian influenza hemagglutinin pseudotyping of lentiviral vectors von MCKAY, T, PATEL, M, PICKLES, R. J, JOHNSON, L. G, OLSEN, J. C

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TLR7 promotes smoke-induced experimental lung damage through the activity of mast cell tryptase von Liu, G, Haw, TJ, Starkey, MR, Philp, AM, Pavlidis, S, Nalkurthi, C, Nair, PM, Gomez, HM, Hanish, I, Hsu, AC, Hortle, E, Pickles, S, Rojas-Quintero, J, Estepar, RSJ, Marshall, JE, Kim, RY, Collison, AM, Mattes, J, Idrees, S, Faiz, A, Hansbro, NG, Fukui, R, Murakami, Y, Cheng, HS, Tan, NS, Chotirmall, SH, Horvat, JC, Foster, PS, Oliver, BG, Polverino, F, Ieni, A, Monaco, F, Caramori, G, Sohal, SS, Bracke, KR, Wark, PA, Adcock, IM, Miyake, K, Sin, DD, Hansbro, PM

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Estimating early HIV risk among at risk adolescent girls and young women in Dnipro, Ukraine von Becker, Marissa, Balakireva, Olga, Isac, Shajy, Cheuk, Eve, Pavlova, Daryna, McLarty, Leigh, Mishra, Sharmistha, Pickles, Michael, Lorway, Robert, Sandstrom, Paul, Blanchard, James, Nugent, Zoann

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Light hadron spectroscopy with O ( a ) improved dynamical fermions von Allton, C. R., Booth, S. P., Bowler, K. C., Foster, M., Garden, J., Irving, A. C., Kenway, R. D., Michael, C., Peisa, J., Pickles, S. M., Sexton, J. C., Sroczynski, Z., Talevi, M., Wittig, H.

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Transduction of Non-Small Cell Lung Cancer Cells by Adenoviral and Retroviral Vectors von Batra, Raj K, Olsen, John C, Pickles, Raymond J, Hoganson, Diana K, Boucher, Richard C

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In vitro assessment of variables affecting the efficiency and efficacy of adenovirus-mediated gene transfer to cystic fibrosis airway epithelia von Johnson, L G, Pickles, R J, Boyles, S E, Morris, J C, Ye, H, Zhou, Z, Olsen, J C, Boucher, R C

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